| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.138121 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.131112 |
| PTMA | prothymosin, alpha | 0.125277 |
| VCL | vinculin | 0.0964584 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0754646 |
| TXNRD1 | thioredoxin reductase 1 | 0.0697795 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0673966 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0587647 |
| PKM | pyruvate kinase, muscle | 0.0563762 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0561212 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0548125 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0511921 |
| GOLGA4 | golgin A4 | 0.0499911 |
| FLNB | filamin B, beta | 0.0467014 |
| RPS6 | ribosomal protein S6 | 0.045628 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0445981 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0433926 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0430317 |
| RHOA | ras homolog family member A | 0.0418843 |
| RTN4 | reticulon 4 | 0.0414896 |
| B2M | beta-2-microglobulin | 0.0413841 |
| S100A6 | S100 calcium binding protein A6 | 0.0392807 |
| PYGB | phosphorylase, glycogen; brain | 0.0392644 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0390608 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0365412 |
| RPL26 | ribosomal protein L26 | 0.0358904 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0351469 |
| SQSTM1 | sequestosome 1 | 0.0341909 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0340851 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0337234 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0335429 |
| EGFR | epidermal growth factor receptor | 0.0334156 |
| PDGFC | platelet derived growth factor C | 0.0323089 |
| ANK2 | ankyrin 2, neuronal | 0.0317616 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0311569 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0306292 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.030557 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0300907 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0297937 |
| RPL3 | ribosomal protein L3 | 0.0294591 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.029123 |
| JMJD1C | jumonji domain containing 1C | 0.0288553 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0287515 |
| VMP1 | vacuole membrane protein 1 | 0.0283622 |
| RPL12 | ribosomal protein L12 | 0.0282568 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0274982 |
| METTL15 | methyltransferase like 15 | 0.0274258 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0265827 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0260193 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0258766 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0258134 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0254918 |
| SBF2 | SET binding factor 2 | 0.0254684 |
| COG5 | component of oligomeric golgi complex 5 | 0.0254525 |
| RNF145 | ring finger protein 145 | 0.0254202 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0253672 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0253479 |
| ENO1 | enolase 1, (alpha) | 0.0252504 |
| TMEM65 | transmembrane protein 65 | 0.0246652 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0244589 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0237758 |
| RPL11 | ribosomal protein L11 | 0.0237311 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0234322 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0232783 |
| PTEN | phosphatase and tensin homolog | 0.0232253 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0229457 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0226007 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0223958 |
| RACK1 | receptor for activated C kinase 1 | 0.0223507 |
| CLTC | clathrin, heavy chain (Hc) | 0.0220283 |
| RBM25 | RNA binding motif protein 25 | 0.021956 |
| ATF4 | activating transcription factor 4 | 0.0216971 |
| RUSC2 | RUN and SH3 domain containing 2 | 0.0216951 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0216325 |
| THOC2 | THO complex 2 | 0.0215424 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0215107 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0214686 |
| TMEM14B | transmembrane protein 14B | 0.0212481 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0209946 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0204745 |
| ZNF148 | zinc finger protein 148 | 0.0203416 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0201927 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0201591 |
| RPL7A | ribosomal protein L7a | 0.0201421 |
| TMEM41B | transmembrane protein 41B | 0.0200075 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0198877 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0198395 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0197438 |
| AMOTL2 | angiomotin like 2 | 0.0195894 |
| CEP95 | centrosomal protein 95kDa | 0.0195371 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0195117 |
| DSTN | destrin (actin depolymerizing factor) | 0.0192007 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0191811 |
| RPS18 | ribosomal protein S18 | 0.0190233 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0189986 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0187917 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0187129 |
| PNN | pinin, desmosome associated protein | 0.0186834 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0185885 |
| GGNBP2 | gametogenetin binding protein 2 | 0.0185786 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.101239 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0961587 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0955446 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0906778 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0646727 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0583967 |
| BMP10 | bone morphogenetic protein 10 | -0.0556522 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0445198 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0442233 |
| FOXP1 | forkhead box P1 | -0.0430118 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0377746 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0367316 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0355215 |
| GLI3 | GLI family zinc finger 3 | -0.0354793 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0321565 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0304074 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.030306 |
| HDAC9 | histone deacetylase 9 | -0.0277241 |
| NFIA | nuclear factor I/A | -0.0270565 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0251905 |
| QKI | QKI, KH domain containing, RNA binding | -0.0246164 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0238818 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0233126 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.02308 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0219581 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0218418 |
| DIAPH3 | diaphanous-related formin 3 | -0.0212106 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0208375 |
| FUS | FUS RNA binding protein | -0.0207154 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0207099 |
| NAV2 | neuron navigator 2 | -0.0205847 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0205413 |
| BCOR | BCL6 corepressor | -0.0204096 |
| ANXA1 | annexin A1 | -0.0202776 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0197823 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0194543 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0193917 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0192018 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0189778 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0189115 |
| INTS6 | integrator complex subunit 6 | -0.0188387 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.018808 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0182896 |
| ECT2 | epithelial cell transforming 2 | -0.0180419 |
| MYO5C | myosin VC | -0.0173036 |
| RLF | rearranged L-myc fusion | -0.0172063 |
| RYBP | RING1 and YY1 binding protein | -0.0171739 |
| ATOSA | atos homolog A | -0.0171427 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0171105 |
| FER1L6 | fer-1-like family member 6 | -0.016951 |
| ACTN4 | actinin, alpha 4 | -0.0167001 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0166318 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0166295 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0166029 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase | -0.0163765 |
| PDE7B | phosphodiesterase 7B | -0.0163493 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.016264 |
| NOP58 | NOP58 ribonucleoprotein | -0.0161784 |
| RAD18 | RAD18 E3 ubiquitin protein ligase | -0.0160245 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0159684 |
| SEPTIN7 | septin 7 | -0.0157124 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0156222 |
| ZNF438 | zinc finger protein 438 | -0.0155871 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0155522 |
| CTBP2 | C-terminal binding protein 2 | -0.0154636 |
| PSPC1 | paraspeckle component 1 | -0.0154286 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0153944 |
| AEBP2 | AE binding protein 2 | -0.0153375 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.015326 |
| APLF | aprataxin and PNKP like factor | -0.0147627 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.0147063 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0146363 |
| TRERF1 | transcriptional regulating factor 1 | -0.0145039 |
| HMGB1 | high mobility group box 1 | -0.0144179 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0142348 |
| TOP1 | topoisomerase (DNA) I | -0.0142133 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | -0.0139879 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.013852 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0138363 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0137901 |
| MEIS2 | Meis homeobox 2 | -0.0137109 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0136308 |
| SEC24B | SEC24 family member B | -0.0136116 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0134835 |
| PTBP1 | polypyrimidine tract binding protein 1 | -0.0134819 |
| MACROD2 | MACRO domain containing 2 | -0.0133944 |
| ATP11A | ATPase, class VI, type 11A | -0.0133388 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0133224 |
| SGMS2 | sphingomyelin synthase 2 | -0.0132265 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0128567 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0128139 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0128091 |
| SAFB2 | scaffold attachment factor B2 | -0.0127751 |
| NASP | nuclear autoantigenic sperm protein (histone-binding) | -0.0126616 |
| SON | SON DNA binding protein | -0.0125488 |
| SDCBP | syndecan binding protein (syntenin) | -0.0124941 |
| CCDC88A | coiled-coil domain containing 88A | -0.0123942 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.012349 |
| JUN | jun proto-oncogene | -0.0123044 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0122493 |
