| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.104533 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0566477 |
| CCNL1 | cyclin L1 | 0.0551051 |
| ZNF292 | zinc finger protein 292 | 0.0512687 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.051215 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.048564 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.047141 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0465486 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0443656 |
| USP3 | ubiquitin specific peptidase 3 | 0.0438548 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0418285 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0405415 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0400469 |
| MATR3 | matrin 3 | 0.0387392 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0383404 |
| SNX9 | sorting nexin 9 | 0.0377912 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0371611 |
| NCKAP1 | NCK-associated protein 1 | 0.0355176 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0353028 |
| TMSB4X | thymosin beta 4, X-linked | 0.034013 |
| VMP1 | vacuole membrane protein 1 | 0.0339715 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0332918 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0324794 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0324325 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0320262 |
| MTMR3 | myotubularin related protein 3 | 0.0319689 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0318438 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0317621 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0314365 |
| RNF145 | ring finger protein 145 | 0.0312462 |
| NPTN | neuroplastin | 0.0288701 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0288643 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0275062 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0273564 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0272509 |
| FMR1 | fragile X mental retardation 1 | 0.0271663 |
| OLA1 | Obg-like ATPase 1 | 0.025474 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0253147 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0251353 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0250467 |
| MEF2A | myocyte enhancer factor 2A | 0.0247569 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0247475 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0239344 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0235241 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.023479 |
| RBM39 | RNA binding motif protein 39 | 0.0234144 |
| TPM3 | tropomyosin 3 | 0.0231474 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0230157 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0227658 |
| EWSR1 | EWS RNA-binding protein 1 | 0.022344 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.02233 |
| CRY1 | cryptochrome circadian clock 1 | 0.0220541 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0218252 |
| USP6NL | USP6 N-terminal like | 0.0207592 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0207495 |
| FOXJ3 | forkhead box J3 | 0.0207064 |
| PNN | pinin, desmosome associated protein | 0.0203304 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0202845 |
| RTN4 | reticulon 4 | 0.0202594 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0202219 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0201389 |
| RAB18 | RAB18, member RAS oncogene family | 0.0201369 |
| TFG | TRK-fused gene | 0.0200898 |
| TCERG1 | transcription elongation regulator 1 | 0.0200634 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0200366 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0199254 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0197908 |
| AFDN | afadin, adherens junction formation factor | 0.0196496 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0195772 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0194322 |
| DSPP | dentin sialophosphoprotein | 0.0193861 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0192056 |
| SET | SET nuclear proto-oncogene | 0.0190201 |
| ZNF148 | zinc finger protein 148 | 0.0188312 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0186746 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0186518 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0184497 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0183428 |
| TEX10 | testis expressed 10 | 0.0180523 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0180258 |
| ATP13A3 | ATPase type 13A3 | 0.0178583 |
| CCNT2 | cyclin T2 | 0.0178531 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0178513 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0177568 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0175841 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0175692 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0174621 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.017406 |
| FNBP1L | formin binding protein 1-like | 0.0172099 |
| VEGFA | vascular endothelial growth factor A | 0.0171381 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0171167 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0169538 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0169116 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0168539 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0168122 |
| MKRN1 | makorin ring finger protein 1 | 0.0167467 |
| XPO1 | exportin 1 | 0.0167101 |
| SF1 | splicing factor 1 | 0.0166573 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0165679 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0165436 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132446 |
| FTL | ferritin, light polypeptide | -0.118778 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.111046 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0793087 |
| TMSB10 | thymosin beta 10 | -0.0775265 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0763391 |
| RPLP1 | ribosomal protein, large, P1 | -0.0636561 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0626698 |
| EHBP1 | EH domain binding protein 1 | -0.0604989 |
| PTMA | prothymosin, alpha | -0.0593844 |
| RPL35A | ribosomal protein L35a | -0.0588412 |
| EGR1 | early growth response 1 | -0.0582746 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0559315 |
| HM13 | histocompatibility (minor) 13 | -0.0512942 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0489217 |
| RPL23 | ribosomal protein L23 | -0.0489133 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0484701 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0480799 |
| BCL2L1 | BCL2-like 1 | -0.0478068 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.047728 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0471974 |
| ACTG1 | actin gamma 1 | -0.0467029 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0464275 |
| RPLP2 | ribosomal protein, large, P2 | -0.046102 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0460497 |
| VCL | vinculin | -0.042536 |
| RPS19 | ribosomal protein S19 | -0.0416162 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0414824 |
| RPL31 | ribosomal protein L31 | -0.0406419 |
| LDHA | lactate dehydrogenase A | -0.0398879 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0398572 |
| GNAS | GNAS complex locus | -0.0393857 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0386871 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.038656 |
| RPL28 | ribosomal protein L28 | -0.0384729 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0383915 |
| RPS8 | ribosomal protein S8 | -0.0382814 |
| RPL12 | ribosomal protein L12 | -0.0380898 |
| CUX1 | cut-like homeobox 1 | -0.0376229 |
| NEBL | nebulette | -0.0374475 |
| RPS6 | ribosomal protein S6 | -0.0373208 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0372636 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0369775 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0369189 |
| RPS25 | ribosomal protein S25 | -0.0367991 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0366237 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.036271 |
| MYO1E | myosin IE | -0.0359725 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0356506 |
| GOLGB1 | golgin B1 | -0.0355902 |
| CDK13 | cyclin-dependent kinase 13 | -0.0354865 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0350832 |
| IER3 | immediate early response 3 | -0.0349738 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0348146 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0346361 |
| RPL19 | ribosomal protein L19 | -0.0345493 |
| RPL37A | ribosomal protein L37a | -0.0345437 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0341558 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0338161 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0333979 |
| RPS21 | ribosomal protein S21 | -0.0331025 |
| RPS13 | ribosomal protein S13 | -0.0327828 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0320172 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0317272 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0315705 |
| NF1 | neurofibromin 1 | -0.0313918 |
| NFIA | nuclear factor I/A | -0.0312596 |
| PERP | PERP, TP53 apoptosis effector | -0.0301915 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0300737 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0300586 |
| RPS14 | ribosomal protein S14 | -0.030025 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0299537 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0298383 |
| BBX | bobby sox homolog (Drosophila) | -0.0297842 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0296781 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0295975 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0295817 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0295043 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0294942 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0292724 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0290993 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0290989 |
| FRMD5 | FERM domain containing 5 | -0.0290614 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0290302 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0290254 |
| TGFA | transforming growth factor, alpha | -0.0290057 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0289175 |
| HDLBP | high density lipoprotein binding protein | -0.0287566 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0286709 |
| RPS11 | ribosomal protein S11 | -0.0285619 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0285201 |
| SP100 | SP100 nuclear antigen | -0.0282346 |
| RPL32 | ribosomal protein L32 | -0.0280425 |
| TMEM123 | transmembrane protein 123 | -0.0279479 |
| S100A6 | S100 calcium binding protein A6 | -0.027937 |
| RPLP0 | ribosomal protein, large, P0 | -0.027573 |
| RPS24 | ribosomal protein S24 | -0.0275524 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0275241 |
| NDRG1 | N-myc downstream regulated 1 | -0.0273786 |
| RAD51B | RAD51 paralog B | -0.0272461 |