| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methyl aminolevulinate (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methyl aminolevulinate (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.135646 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.115395 |
| B2M | beta-2-microglobulin | 0.107977 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.101178 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0708832 |
| VEGFA | vascular endothelial growth factor A | 0.0706983 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0630578 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0605467 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0599516 |
| GOLGA4 | golgin A4 | 0.0524743 |
| VMP1 | vacuole membrane protein 1 | 0.0520483 |
| COL6A1 | collagen, type VI, alpha 1 | 0.051538 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0513707 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0480678 |
| COPA | coatomer protein complex, subunit alpha | 0.0477306 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0469369 |
| ADM | adrenomedullin | 0.0468217 |
| MYO10 | myosin X | 0.0462214 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0460448 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0447107 |
| SETD5 | SET domain containing 5 | 0.0436463 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0428954 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0424875 |
| RPS6 | ribosomal protein S6 | 0.0418689 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.038008 |
| MMP12 | matrix metallopeptidase 12 | 0.0353037 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0340608 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.03258 |
| TMEM165 | transmembrane protein 165 | 0.0324472 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0310804 |
| TMF1 | TATA element modulatory factor 1 | 0.0305111 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0304976 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0304581 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0301194 |
| ATP13A3 | ATPase type 13A3 | 0.0298429 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0295123 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0294503 |
| NBAS | neuroblastoma amplified sequence | 0.0292233 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.028838 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0280711 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.027851 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0274468 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0269966 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0263171 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0257496 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0256144 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0254625 |
| RPS12 | ribosomal protein S12 | 0.0252656 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0252327 |
| RNF145 | ring finger protein 145 | 0.024695 |
| MSN | moesin | 0.0241411 |
| DNER | delta/notch-like EGF repeat containing | 0.02411 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0240779 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0238901 |
| NAV1 | neuron navigator 1 | 0.023876 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0234604 |
| PDE8A | phosphodiesterase 8A | 0.0231503 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0229985 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0229849 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0228128 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0226196 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0224627 |
| CLMP | CXADR-like membrane protein | 0.0224598 |
| YBX1 | Y box binding protein 1 | 0.0223884 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0221838 |
| GPHN | gephyrin | 0.0220346 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0219007 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0218641 |
| CALR | calreticulin | 0.021758 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0216697 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0206577 |
| NKTR | natural killer cell triggering receptor | 0.0206257 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0205174 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0201509 |
| ZNF148 | zinc finger protein 148 | 0.0197424 |
| FMNL2 | formin-like 2 | 0.0197404 |
| RPS18 | ribosomal protein S18 | 0.0197047 |
| CALD1 | caldesmon 1 | 0.0196801 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0196035 |
| TPM3 | tropomyosin 3 | 0.0195869 |
| CTBP2 | C-terminal binding protein 2 | 0.0195293 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0193902 |
| NOTCH2 | notch 2 | 0.0193686 |
| RPL21 | ribosomal protein L21 | 0.019335 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0193145 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0191786 |
| RPL11 | ribosomal protein L11 | 0.0188889 |
| TFG | TRK-fused gene | 0.0188879 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0188824 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0188808 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0188699 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0188401 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0188076 |
| NUP58 | nucleoporin 58 | 0.0187371 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0186471 |
| RPL26 | ribosomal protein L26 | 0.0185039 |
| MED13L | mediator complex subunit 13-like | 0.018485 |
| TNS1 | tensin 1 | 0.0184536 |
| COL5A3 | collagen, type V, alpha 3 | 0.0184379 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0183485 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.187207 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167703 |
| FN1 | fibronectin 1 | -0.124196 |
| TMSB10 | thymosin beta 10 | -0.0903928 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0710772 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0703131 |
| COL1A1 | collagen, type I, alpha 1 | -0.0661489 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0657309 |
| MMP1 | matrix metallopeptidase 1 | -0.0650334 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0614871 |
| ACTG1 | actin gamma 1 | -0.0608783 |
| INHBA | inhibin, beta A | -0.0570491 |
| ASPH | aspartate beta-hydroxylase | -0.0558077 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0544237 |
| IER3 | immediate early response 3 | -0.0535456 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0489988 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0475377 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0404867 |
| OSMR | oncostatin M receptor | -0.0389818 |
| NDRG1 | N-myc downstream regulated 1 | -0.0385105 |
| COL1A2 | collagen, type I, alpha 2 | -0.0375385 |
| LOXL2 | lysyl oxidase-like 2 | -0.0374145 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0368137 |
| PGK1 | phosphoglycerate kinase 1 | -0.0362689 |
| LDHA | lactate dehydrogenase A | -0.0353257 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0344093 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0341731 |
| VIM | vimentin | -0.0335042 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0328273 |
| STC1 | stanniocalcin 1 | -0.0327491 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0326454 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320022 |
| CAVIN1 | caveolae associated protein 1 | -0.0317192 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0306921 |
| EMP1 | epithelial membrane protein 1 | -0.0306633 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0304225 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0298434 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0291436 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0281999 |
| CCND1 | cyclin D1 | -0.0281672 |
| PLPP3 | phospholipid phosphatase 3 | -0.0277129 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0267587 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.02646 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0263403 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0258305 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0256259 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0255555 |
| SMAD3 | SMAD family member 3 | -0.0253907 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0253351 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0250036 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0246562 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.024625 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0245931 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0245356 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0241202 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0239364 |
| RAI14 | retinoic acid induced 14 | -0.0236995 |
| RUNX1 | runt-related transcription factor 1 | -0.0235133 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0233658 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0232619 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0227978 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0226077 |
| HDLBP | high density lipoprotein binding protein | -0.0224388 |
| RPL27A | ribosomal protein L27a | -0.0221826 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0221079 |
| HLA-E | major histocompatibility complex, class I, E | -0.0220293 |
| RPS24 | ribosomal protein S24 | -0.0219509 |
| ARF1 | ADP-ribosylation factor 1 | -0.0216067 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0203155 |
| THBS2 | thrombospondin 2 | -0.0202138 |
| RTN4 | reticulon 4 | -0.0201816 |
| RYBP | RING1 and YY1 binding protein | -0.0198691 |
| FRMD4A | FERM domain containing 4A | -0.0196249 |
| TXNRD1 | thioredoxin reductase 1 | -0.0195992 |
| HLA-C | major histocompatibility complex, class I, C | -0.0193902 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0193875 |
| RPL38 | ribosomal protein L38 | -0.0193363 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.019066 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0189319 |
| SQSTM1 | sequestosome 1 | -0.0188731 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0183669 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0180785 |
| SYAP1 | synapse associated protein 1 | -0.0179193 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0179108 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0177531 |
| CALU | calumenin | -0.0177277 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0177106 |
| HMGB1 | high mobility group box 1 | -0.0176242 |
| UBB | ubiquitin B | -0.0173993 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0172612 |
| NRP1 | neuropilin 1 | -0.017257 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0172534 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0172332 |
| AFAP1 | actin filament associated protein 1 | -0.0172056 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | -0.017083 |
| COL5A2 | collagen, type V, alpha 2 | -0.017033 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0168837 |
| FRMD6 | FERM domain containing 6 | -0.0168827 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0168736 |
| TPM4 | tropomyosin 4 | -0.0168543 |
