Methylosome Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains. (Gene Ontology, GO_0034709)
External Link http://amigo.geneontology.org/amigo/term/GO:0034709
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462 proteins co-occuring with the Methylosome cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
WDR77 WD repeat domain 77 3.496
PRMT5 protein arginine methyltransferase 5 3.252
RIOK1 RIO kinase 1 2.763
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.617
CHTOP chromatin target of PRMT1 2.54
COPRS coordinator of PRMT5, differentiation stimulator 2.456
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 2.455
PRMT7 protein arginine methyltransferase 7 2.432
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.423
PRMT1 protein arginine methyltransferase 1 2.371
GEMIN2 gem (nuclear organelle) associated protein 2 2.264
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 2.258
MTAP methylthioadenosine phosphorylase 2.154
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 2.079
SRFBP1 serum response factor binding protein 1 2.06
SNRPE small nuclear ribonucleoprotein polypeptide E 1.969
PRMT6 protein arginine methyltransferase 6 1.925
PRMT8 protein arginine methyltransferase 8 1.923
ZNF326 zinc finger protein 326 1.884
PRMT2 protein arginine methyltransferase 2 1.789
GEMIN5 gem (nuclear organelle) associated protein 5 1.781
ERH enhancer of rudimentary homolog (Drosophila) 1.728
GEMIN8 gem (nuclear organelle) associated protein 8 1.721
CARM1 coactivator-associated arginine methyltransferase 1 1.699
MAGOHB mago-nashi homolog B (Drosophila) 1.697
H4C7 H4 clustered histone 7 1.695
VIRMA vir like m6A methyltransferase associated 1.692
H4C15 H4 clustered histone 15 1.677
TDRD6 tudor domain containing 6 1.677
LIN9 lin-9 DREAM MuvB core complex component 1.673
COIL coilin 1.656
GEMIN7 gem (nuclear organelle) associated protein 7 1.653
TDRD1 tudor domain containing 1 1.639
LSM10 LSM10, U7 small nuclear RNA associated 1.635
PRMT3 protein arginine methyltransferase 3 1.635
SLMAP sarcolemma associated protein 1.624
DYDC1 DPY30 domain containing 1 1.622
METTL14 methyltransferase like 14 1.612
WTAP Wilms tumor 1 associated protein 1.59
METTL3 methyltransferase like 3 1.588
LSM11 LSM11, U7 small nuclear RNA associated 1.584
SMN1 survival of motor neuron 1, telomeric 1.576
RPS10 ribosomal protein S10 1.572
AREG amphiregulin 1.571
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.553
RIOK2 RIO kinase 2 1.537
TDRD3 tudor domain containing 3 1.514
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.496
TET1 tet methylcytosine dioxygenase 1 1.486
SMN2 survival of motor neuron 2, centromeric 1.472
GEMIN6 gem (nuclear organelle) associated protein 6 1.457
SMG7 SMG7 nonsense mediated mRNA decay factor 1.452
RBM15 RNA binding motif protein 15 1.45
MDM4 MDM4, p53 regulator 1.448
TDRKH tudor and KH domain containing 1.442
TXNL4B thioredoxin-like 4B 1.431
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 1.407
RIOK3 RIO kinase 3 1.406
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 1.4
PIWIL1 piwi-like RNA-mediated gene silencing 1 1.399
GEMIN4 gem (nuclear organelle) associated protein 4 1.392
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 1.377
SMNDC1 survival motor neuron domain containing 1 1.369
PIWIL4 piwi-like RNA-mediated gene silencing 4 1.36
TP53 tumor protein p53 1.357
E2F1 E2F transcription factor 1 1.357
H2AC20 H2A clustered histone 20 1.345
H2AC19 H2A clustered histone 19 1.344
ZC3H13 zinc finger CCCH-type containing 13 1.33
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.328
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.307
RPL7L1 ribosomal protein L7-like 1 1.302
OBI1 ORC ubiquitin ligase 1 1.295
SNRPC small nuclear ribonucleoprotein polypeptide C 1.289
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 1.282
TRIML2 tripartite motif family-like 2 1.265
AKT3 v-akt murine thymoma viral oncogene homolog 3 1.26
ALKBH5 AlkB family member 5, RNA demethylase 1.257
WDR5 WD repeat domain 5 1.255
LRP12 low density lipoprotein receptor-related protein 12 1.25
TRNAU1AP tRNA selenocysteine 1 associated protein 1 1.245
FTO fat mass and obesity associated 1.241
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 1.226
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.223
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) 1.222
TDRD12 tudor domain containing 12 1.221
GIGYF1 GRB10 interacting GYF protein 1 1.22
RBM8A RNA binding motif protein 8A 1.217
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1.211
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.21
EGFR epidermal growth factor receptor 1.207
NOAZFP nucleolar atypical zinc finger 1.206
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 1.189
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 1.187
RPL3L ribosomal protein L3-like 1.183
MAPK4 mitogen-activated protein kinase 4 1.172
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.163
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 1.162
PPHLN1 periphilin 1 1.155
ESR1 estrogen receptor 1 1.151
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.151
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.15
TCERG1 transcription elongation regulator 1 1.148
TASOR transcription activation suppressor 1.14
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 1.135
SNRPN small nuclear ribonucleoprotein polypeptide N 1.133
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) 1.126
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 1.125
OTUD6B OTU domain containing 6B 1.122
BYSL bystin-like 1.119
RNF17 ring finger protein 17 1.109
MAT2A methionine adenosyltransferase II, alpha 1.105
PRMT9 protein arginine methyltransferase 9 1.099
AVEN apoptosis, caspase activation inhibitor 1.089
BRWD3 bromodomain and WD repeat domain containing 3 1.086
CDK6 cyclin-dependent kinase 6 1.084
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 1.082
SNRPA small nuclear ribonucleoprotein polypeptide A 1.078
H3-5 H3.5 histone 1.077
H3-4 H3.4 histone, cluster member 1.076
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.076
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 1.073
SNRPG small nuclear ribonucleoprotein polypeptide G 1.071
CDKN2A cyclin-dependent kinase inhibitor 2A 1.069
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 1.066
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.063
SF3B2 splicing factor 3b, subunit 2, 145kDa 1.063
ZNF598 zinc finger protein 598 1.061
KMT5A lysine methyltransferase 5A 1.058
H1-2 H1.2 linker histone, cluster member 1.056
SETD7 SET domain containing (lysine methyltransferase) 7 1.052
TET3 tet methylcytosine dioxygenase 3 1.052
H3C7 H3 clustered histone 7 1.05
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 1.049
SF3A1 splicing factor 3a, subunit 1, 120kDa 1.044
DPEP2 dipeptidase 2 1.043
H3-7 H3.7 histone (putative) 1.04
PIWIL2 piwi-like RNA-mediated gene silencing 2 1.039
H3C13 H3 clustered histone 13 1.039
SRSF2 serine/arginine-rich splicing factor 2 1.039
EWSR1 EWS RNA-binding protein 1 1.038
SNRPF small nuclear ribonucleoprotein polypeptide F 1.034
SF3B5 splicing factor 3b, subunit 5, 10kDa 1.032
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B 1.031
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.029
SRP72 signal recognition particle 72kDa 1.028
TDRD7 tudor domain containing 7 1.018
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 1.011
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.009
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) 1.008
EIF4E eukaryotic translation initiation factor 4E 1.007
CCND2 cyclin D2 1.007
RNF6 ring finger protein (C3H2C3 type) 6 1.005
REPIN1 replication initiator 1 1.004
KAT5 K(lysine) acetyltransferase 5 0.994
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.987
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 0.987
CDK4 cyclin-dependent kinase 4 0.986
EHMT2 euchromatic histone-lysine N-methyltransferase 2 0.981
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 0.98
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 0.978
FUS FUS RNA binding protein 0.977
LSM1 LSM1, U6 small nuclear RNA associated 0.976
YTHDC1 YTH domain containing 1 0.975
RPS26 ribosomal protein S26 0.972
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.971
CCNE1 cyclin E1 0.97
LZTR1 leucine-zipper-like transcription regulator 1 0.97
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.97
RBM5 RNA binding motif protein 5 0.964
TSLIG3A tRNA splicing ligase complex subunit 3A 0.964
NCDN neurochondrin 0.963
SMG5 SMG5 nonsense mediated mRNA decay factor 0.962
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.96
KMT5C lysine methyltransferase 5C 0.959
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.956
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) 0.95
FBXO6 F-box protein 6 0.938
ZNF579 zinc finger protein 579 0.937
YBX1 Y box binding protein 1 0.934
SRSF1 serine/arginine-rich splicing factor 1 0.934
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.932
SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.931
EIF3M eukaryotic translation initiation factor 3, subunit M 0.93
LTV1 LTV1 ribosome biogenesis factor 0.928
KMT5B lysine methyltransferase 5B 0.925
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 0.923
ZNF224 zinc finger protein 224 0.922
KDM1A lysine (K)-specific demethylase 1A 0.922
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 0.922
RPS2 ribosomal protein S2 0.917
EIF4A3 eukaryotic translation initiation factor 4A3 0.917
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.914
TASOR2 transcription activation suppressor family member 2 0.912
CCND1 cyclin D1 0.908
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.896
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.894
TRA2B transformer 2 beta homolog (Drosophila) 0.894
GPATCH3 G patch domain containing 3 0.892
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.891
MSL2 male-specific lethal 2 homolog (Drosophila) 0.889
RUVBL1 RuvB-like AAA ATPase 1 0.887
PHAX phosphorylated adaptor for RNA export 0.887
SRP19 signal recognition particle 19kDa 0.885
FBL fibrillarin 0.885
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.875
SSC4D scavenger receptor cysteine rich family, 4 domains 0.874
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.872
SRSF3 serine/arginine-rich splicing factor 3 0.864
PMPCA peptidase (mitochondrial processing) alpha 0.861
SELENOT selenoprotein T 0.857
CDK2 cyclin-dependent kinase 2 0.857
PTEN phosphatase and tensin homolog 0.856
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) 0.856
EEFSEC eukaryotic elongation factor, selenocysteine-tRNA-specific 0.849
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.848
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.845
SECISBP2 SECIS binding protein 2 0.836
KLF14 Kruppel-like factor 14 0.835
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.832
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 0.828
SHARPIN SHANK-associated RH domain interactor 0.826
FMR1 fragile X mental retardation 1 0.826
CAPRIN1 cell cycle associated protein 1 0.819
METTL1 methyltransferase like 1 0.816
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 0.815
MSRB1 methionine sulfoxide reductase B1 0.814
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.814
RUVBL2 RuvB-like AAA ATPase 2 0.813
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) 0.811
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.805
SND1 staphylococcal nuclease and tudor domain containing 1 0.8
MTDH metadherin 0.8
RPS3 ribosomal protein S3 0.797
EIF4E2 eukaryotic translation initiation factor 4E family member 2 0.796
RBM48 RNA binding motif protein 48 0.794
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 0.793
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.793
TUBA1A tubulin, alpha 1a 0.791
SLX9 SLX9 ribosome biogenesis factor 0.79
FBXO24 F-box protein 24 0.788
TSPYL4 TSPY-like 4 0.787
TET2 tet methylcytosine dioxygenase 2 0.786
GMPR2 guanosine monophosphate reductase 2 0.785
PSME3IP1 proteasome activator subunit 3 interacting protein 1 0.784
PRDM1 PR domain containing 1, with ZNF domain 0.781
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.781
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.779
HRH4 histamine receptor H4 0.778
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.772
POTEF POTE ankyrin domain family, member F 0.771
PHF1 PHD finger protein 1 0.768
FXR1 fragile X mental retardation, autosomal homolog 1 0.765
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.765
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 0.761
CCNA2 cyclin A2 0.76
RELL2 RELT-like 2 0.757
EFHB EF-hand domain family, member B 0.752
TUBA3E tubulin, alpha 3e 0.752
AGO1 argonaute RISC catalytic component 1 0.752
TUBAL3 tubulin, alpha-like 3 0.749
MYO15B myosin XVB 0.749
RAD23A RAD23 homolog A (S. cerevisiae) 0.748
TRIM28 tripartite motif containing 28 0.748
H3-3B H3.3 histone B 0.746
SETDB1 SET domain, bifurcated 1 0.746
PABPC1 poly(A) binding protein, cytoplasmic 1 0.745
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.745
RBM23 RNA binding motif protein 23 0.741
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.74
DNAAF2 dynein, axonemal, assembly factor 2 0.74
PLRG1 pleiotropic regulator 1 0.739
SETD1A SET domain containing 1A 0.739
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.739
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.737
XPO1 exportin 1 0.734
JDP2 Jun dimerization protein 2 0.734
EGF epidermal growth factor 0.728
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 0.728
KHDC4 KH domain containing 4, pre-mRNA splicing factor 0.727
EIF1AD eukaryotic translation initiation factor 1A domain containing 0.725
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.724
RBM39 RNA binding motif protein 39 0.724
FAF1 Fas (TNFRSF6) associated factor 1 0.724
CLSTN1 calsyntenin 1 0.724
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.722
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.721
CENPV centromere protein V 0.715
NUAK1 NUAK family, SNF1-like kinase, 1 0.715
SMG6 SMG6 nonsense mediated mRNA decay factor 0.714
LCE1C late cornified envelope 1C 0.714
FXR2 fragile X mental retardation, autosomal homolog 2 0.714
CCNA1 cyclin A1 0.713
SETD2 SET domain containing 2 0.706
TUBA3D tubulin, alpha 3d 0.705
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.705
RUFY2 RUN and FYVE domain containing 2 0.703
FBLL1 fibrillarin-like 1 0.702
NHEJ1 nonhomologous end-joining factor 1 0.701
TUBA8 tubulin, alpha 8 0.701
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 0.699
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 0.698
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa 0.695
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.694
MEN1 multiple endocrine neoplasia I 0.692
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.689
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.688
PRPF31 pre-mRNA processing factor 31 0.687
SMYD3 SET and MYND domain containing 3 0.683
TUBA4A tubulin, alpha 4a 0.682
TRA2A transformer 2 alpha homolog (Drosophila) 0.681
KLK10 kallikrein-related peptidase 10 0.679
PXDNL peroxidasin-like 0.679
PXDN peroxidasin 0.678
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 0.677
RUNX1 runt-related transcription factor 1 0.677
CCDC59 coiled-coil domain containing 59 0.675
MGMT O-6-methylguanine-DNA methyltransferase 0.674
DNAH8 dynein, axonemal, heavy chain 8 0.674
HRH3 histamine receptor H3 0.673
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.668
PRPF4B pre-mRNA processing factor 4B 0.668
TCHP trichoplein, keratin filament binding 0.665
FOXD1 forkhead box D1 0.664
SRSF10 serine/arginine-rich splicing factor 10 0.663
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 0.663
ALYREF Aly/REF export factor 0.662
RPL13A ribosomal protein L13a 0.661
AHCY adenosylhomocysteinase 0.656
LIN28B lin-28 homolog B (C. elegans) 0.656
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 0.651
CHEK2 checkpoint kinase 2 0.65
METTL21A methyltransferase like 21A 0.65
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.649
NCOA4 nuclear receptor coactivator 4 0.649
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 0.647
JUN jun proto-oncogene 0.646
DROSHA drosha, ribonuclease type III 0.646
TUBA1C tubulin, alpha 1c 0.644
TDRD9 tudor domain containing 9 0.643
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 0.642
RBM26 RNA binding motif protein 26 0.64
CREB3L1 cAMP responsive element binding protein 3-like 1 0.637
HNRNPF heterogeneous nuclear ribonucleoprotein F 0.636
SREBF1 sterol regulatory element binding transcription factor 1 0.635
JMJD6 jumonji domain containing 6 0.633
THRAP3 thyroid hormone receptor associated protein 3 0.632
ZPR1 ZPR1 zinc finger 0.63
CWC22 CWC22 spliceosome-associated protein 0.63
DCP1A decapping mRNA 1A 0.63
RCOR1 REST corepressor 1 0.63
MAEL maelstrom spermatogenic transposon silencer 0.628
SP6 Sp6 transcription factor 0.627
STAU2 staufen double-stranded RNA binding protein 2 0.626
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.624
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.623
BTG2 BTG family, member 2 0.62
TUBA1B tubulin, alpha 1b 0.619
FOXM1 forkhead box M1 0.616
LARP1 La ribonucleoprotein domain family, member 1 0.615
RAD9A RAD9 homolog A (S. pombe) 0.615
RBM17 RNA binding motif protein 17 0.615
SRPK1 SRSF protein kinase 1 0.615
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.613
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.611
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.61
METTL16 methyltransferase like 16 0.606
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.606
VCX3A variable charge, X-linked 3A 0.605
PNRC1 proline-rich nuclear receptor coactivator 1 0.603
CDCA3 cell division cycle associated 3 0.603
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.601
KAT2A K(lysine) acetyltransferase 2A 0.601
MAP2K1 mitogen-activated protein kinase kinase 1 0.6
MTREX Mtr4 exosome RNA helicase 0.599
METTL4 methyltransferase like 4 0.598
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) 0.597
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.595
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 0.594
SMIM44 small integral membrane protein 44 0.593
FBF1 Fas (TNFRSF6) binding factor 1 0.593
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.589
REST RE1-silencing transcription factor 0.588
ZNHIT2 zinc finger, HIT-type containing 2 0.588
SOX2 SRY (sex determining region Y)-box 2 0.587
ATM ATM serine/threonine kinase 0.584
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.577
SRP9 signal recognition particle 9kDa 0.577
CDK1 cyclin-dependent kinase 1 0.577
TOP1 topoisomerase (DNA) I 0.576
NANOG Nanog homeobox 0.576
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.575
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 0.573
BRCA1 breast cancer 1, early onset 0.572
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.571
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.57
MRPL54 mitochondrial ribosomal protein L54 0.568
GAR1 GAR1 ribonucleoprotein 0.567
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.567
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.566
VASP vasodilator-stimulated phosphoprotein 0.565
NOBOX NOBOX oogenesis homeobox 0.565
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.564
TP53BP1 tumor protein p53 binding protein 1 0.562
MRPL55 mitochondrial ribosomal protein L55 0.562
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.559
H3Y2 H3.Y histone 2 0.558
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.557
MRPS11 mitochondrial ribosomal protein S11 0.554
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.552
FBXO11 F-box protein 11 0.551
CCT7 chaperonin containing TCP1, subunit 7 (eta) 0.55
TPI1 triosephosphate isomerase 1 0.55
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.548
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 0.547
CENPF centromere protein F, 350/400kDa 0.547
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.546
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.546
FAT3 FAT atypical cadherin 3 0.544
NR4A1AS NR4A1 antisense RNA 0.541
CDPF1 cysteine-rich, DPF motif domain containing 1 0.539
PRPF39 pre-mRNA processing factor 39 0.538
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.538
PTCH1 patched 1 0.537
TCF21 transcription factor 21 0.536
AKAP9 A kinase (PRKA) anchor protein 9 0.535
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 0.532
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.531
PNN pinin, desmosome associated protein 0.53
RSAD2 radical S-adenosyl methionine domain containing 2 0.529
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.529
AURKA aurora kinase A 0.528
MEPCE methylphosphate capping enzyme 0.528
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.527
FOXP1 forkhead box P1 0.527
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.526
FOCAD focadhesin 0.526
SERBP1 SERPINE1 mRNA binding protein 1 0.525
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.522
CDC5L cell division cycle 5-like 0.522
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.52
DAPK3 death-associated protein kinase 3 0.519
GSK3B glycogen synthase kinase 3 beta 0.518
SLCO5A1 solute carrier organic anion transporter family, member 5A1 0.517
SRPK2 SRSF protein kinase 2 0.517
FOS FBJ murine osteosarcoma viral oncogene homolog 0.515
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.513
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 0.511
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.51
RBM10 RNA binding motif protein 10 0.51
MRPS9 mitochondrial ribosomal protein S9 0.509
CDK19 cyclin-dependent kinase 19 0.507
U2SURP U2 snRNP-associated SURP domain containing 0.507
NCOA3 nuclear receptor coactivator 3 0.507
PRDX2 peroxiredoxin 2 0.506
MDC1 mediator of DNA-damage checkpoint 1 0.506
KLF4 Kruppel-like factor 4 (gut) 0.506
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.504
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 0.503
PABPN1 poly(A) binding protein, nuclear 1 0.502
SRSF9 serine/arginine-rich splicing factor 9 0.502
FBXO10 F-box protein 10 0.502