| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.368402 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.122624 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.100307 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0951358 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0921911 |
| PEG10 | paternally expressed 10 | 0.086731 |
| OGA | O-GlcNAcase | 0.0753064 |
| MED13L | mediator complex subunit 13-like | 0.0734451 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0710758 |
| ZNF292 | zinc finger protein 292 | 0.0629906 |
| NFIB | nuclear factor I/B | 0.0557521 |
| PCBP2 | poly(rC) binding protein 2 | 0.0519285 |
| CALR | calreticulin | 0.0515371 |
| PRELID2 | PRELI domain containing 2 | 0.0510701 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0497791 |
| SBF2 | SET binding factor 2 | 0.0495313 |
| ENO1 | enolase 1, (alpha) | 0.0490823 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0483205 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0479163 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0468623 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0458178 |
| SFTPA2 | surfactant protein A2 | 0.0454422 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0421089 |
| SPAG9 | sperm associated antigen 9 | 0.0418921 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0416831 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0415304 |
| GOLGA4 | golgin A4 | 0.0407426 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.0392534 |
| PDGFC | platelet derived growth factor C | 0.037532 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0371865 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0362171 |
| GSE1 | Gse1 coiled-coil protein | 0.0355246 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0345403 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0343499 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0339644 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0337289 |
| COL1A2 | collagen, type I, alpha 2 | 0.0333664 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0332862 |
| JMJD1C | jumonji domain containing 1C | 0.0331261 |
| EXOC4 | exocyst complex component 4 | 0.0327888 |
| SEPTIN11 | septin 11 | 0.0327602 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0326908 |
| APP | amyloid beta (A4) precursor protein | 0.0322116 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0321463 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0319389 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0318561 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0316954 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0314062 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0312877 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0311212 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0309652 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.030469 |
| SRPK2 | SRSF protein kinase 2 | 0.030183 |
| EGFR | epidermal growth factor receptor | 0.0300784 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0300123 |
| KIF11 | kinesin family member 11 | 0.0300023 |
| BBX | bobby sox homolog (Drosophila) | 0.0299768 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.029499 |
| RAD51B | RAD51 paralog B | 0.0293124 |
| UBQLN1 | ubiquilin 1 | 0.0292612 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0290885 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0290875 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0289596 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0288794 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0288216 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0285047 |
| XPO1 | exportin 1 | 0.0284847 |
| HMGA2 | high mobility group AT-hook 2 | 0.0284496 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0281905 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0280324 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0278632 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0278419 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0277946 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0277342 |
| SMAP1 | small ArfGAP 1 | 0.0274755 |
| PGK1 | phosphoglycerate kinase 1 | 0.0271664 |
| NBAS | neuroblastoma amplified sequence | 0.0270138 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0269514 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0268636 |
| PANK3 | pantothenate kinase 3 | 0.0268483 |
| TPM4 | tropomyosin 4 | 0.0263262 |
| YEATS2 | YEATS domain containing 2 | 0.0262527 |
| MKI67 | marker of proliferation Ki-67 | 0.026118 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0260936 |
| DIPK2A | divergent protein kinase domain 2A | 0.0260177 |
| TPK1 | thiamin pyrophosphokinase 1 | 0.0259307 |
| CENPE | centromere protein E, 312kDa | 0.0258086 |
| ARRDC3 | arrestin domain containing 3 | 0.025631 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0256184 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.025504 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0252148 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0251957 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0251859 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0251823 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0251731 |
| WWOX | WW domain containing oxidoreductase | 0.0251637 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.025134 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0251086 |
| LDHA | lactate dehydrogenase A | 0.0249601 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0249445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0842695 |
| TMSB10 | thymosin beta 10 | -0.0523908 |
| MT2A | metallothionein 2A | -0.0445894 |
| MGP | matrix Gla protein | -0.0429997 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0421513 |
| RPL35A | ribosomal protein L35a | -0.0416528 |
| RPS8 | ribosomal protein S8 | -0.0381186 |
| RPL31 | ribosomal protein L31 | -0.0380573 |
| RPS23 | ribosomal protein S23 | -0.0367274 |
| RPS6 | ribosomal protein S6 | -0.0358903 |
| RPS19 | ribosomal protein S19 | -0.0354697 |
| RPL32 | ribosomal protein L32 | -0.0313405 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0301949 |
| ACTG1 | actin gamma 1 | -0.0294136 |
| RPLP2 | ribosomal protein, large, P2 | -0.027211 |
| RPS24 | ribosomal protein S24 | -0.0267921 |
| FTL | ferritin, light polypeptide | -0.026288 |
| IER3 | immediate early response 3 | -0.0260559 |
| RPL23 | ribosomal protein L23 | -0.0246884 |
| EGR1 | early growth response 1 | -0.0241258 |
| RPLP1 | ribosomal protein, large, P1 | -0.024033 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0238239 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | -0.0236735 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0236597 |
| RPS14 | ribosomal protein S14 | -0.0233371 |
| VIM | vimentin | -0.02316 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0229726 |
| RPL36 | ribosomal protein L36 | -0.0228858 |
| RPS29 | ribosomal protein S29 | -0.0224096 |
| CDK12 | cyclin-dependent kinase 12 | -0.0220474 |
| RPS25 | ribosomal protein S25 | -0.0218835 |
| CADM2 | cell adhesion molecule 2 | -0.0216384 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0214062 |
| RPL34 | ribosomal protein L34 | -0.0212189 |
| GPC6 | glypican 6 | -0.020886 |
| PHF14 | PHD finger protein 14 | -0.0205437 |
| HDAC8 | histone deacetylase 8 | -0.0203419 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0201374 |
| RPS4X | ribosomal protein S4, X-linked | -0.0200472 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0196991 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0196653 |
| NSA2 | NSA2 ribosome biogenesis homolog (S. cerevisiae) | -0.0194356 |
| CBFB | core-binding factor, beta subunit | -0.019153 |
| FBXO11 | F-box protein 11 | -0.0190829 |
| RPL26 | ribosomal protein L26 | -0.0190746 |
| RPL38 | ribosomal protein L38 | -0.0188159 |
| RACK1 | receptor for activated C kinase 1 | -0.0186796 |
| RPL12 | ribosomal protein L12 | -0.0184183 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0183506 |
| HECTD4 | HECT domain containing E3 ubiquitin protein ligase 4 | -0.0182766 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0182097 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -0.018109 |
| TUT4 | terminal uridylyl transferase 4 | -0.0178833 |
| RPL19 | ribosomal protein L19 | -0.0178487 |
| RPL36A | ribosomal protein L36a | -0.0177966 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0177428 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0176448 |
| ATP11A | ATPase, class VI, type 11A | -0.0175797 |
| RPL37 | ribosomal protein L37 | -0.0174268 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0173835 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | -0.0171786 |
| CFDP1 | craniofacial development protein 1 | -0.0171118 |
| RPS15 | ribosomal protein S15 | -0.017082 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.016896 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0168563 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0168413 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.016802 |
| RPS27A | ribosomal protein S27a | -0.0166414 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0165497 |
| PRAME | preferentially expressed antigen in melanoma | -0.0164686 |
| HMGB1 | high mobility group box 1 | -0.0163119 |
| NPR2 | natriuretic peptide receptor 2 | -0.0159712 |
| RPS5 | ribosomal protein S5 | -0.0159154 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0158139 |
| HMGA1 | high mobility group AT-hook 1 | -0.0154782 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0154739 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0152907 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0152164 |
| AGMO | alkylglycerol monooxygenase | -0.0151244 |
| S100A9 | S100 calcium binding protein A9 | -0.0149755 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0149711 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0149342 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0149191 |
| KLHL20 | kelch-like family member 20 | -0.0146164 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | -0.014532 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0144735 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0144579 |
| NNT | nicotinamide nucleotide transhydrogenase | -0.0142315 |
| PFN1 | profilin 1 | -0.0141756 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0141746 |
| RBM25 | RNA binding motif protein 25 | -0.0141642 |
| RPS16 | ribosomal protein S16 | -0.0141325 |
| POM121C | POM121 transmembrane nucleoporin C | -0.014078 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -0.0140755 |
| CTSD | cathepsin D | -0.0140611 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0138966 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa | -0.0138421 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0138279 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0137591 |
| RPL7A | ribosomal protein L7a | -0.0137561 |
