| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Methylprednisolone succinate_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.165219 |
| FLNB | filamin B, beta | 0.154947 |
| NDRG1 | N-myc downstream regulated 1 | 0.137554 |
| POTEF | POTE ankyrin domain family, member F | 0.137439 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.117718 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.116268 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.113741 |
| MUC17 | mucin 17, cell surface associated | 0.112531 |
| EZR | ezrin | 0.0975934 |
| SPAG9 | sperm associated antigen 9 | 0.0902057 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.089628 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0853221 |
| PCBP2 | poly(rC) binding protein 2 | 0.0805104 |
| FAM107B | family with sequence similarity 107, member B | 0.080426 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0752809 |
| RIOK3 | RIO kinase 3 | 0.0735716 |
| PGK1 | phosphoglycerate kinase 1 | 0.0657926 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0640019 |
| ITGA6 | integrin, alpha 6 | 0.0637644 |
| PTMA | prothymosin, alpha | 0.0636609 |
| PLEC | plectin | 0.0630495 |
| LDHA | lactate dehydrogenase A | 0.0616254 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0607412 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0594638 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0586043 |
| TPM3 | tropomyosin 3 | 0.0573515 |
| RCOR1 | REST corepressor 1 | 0.0573006 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0568006 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0567174 |
| OGA | O-GlcNAcase | 0.0564934 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0540964 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0539695 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0507557 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0502564 |
| EGFR | epidermal growth factor receptor | 0.0478599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0460486 |
| DSPP | dentin sialophosphoprotein | 0.0458535 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0441976 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.044125 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0440394 |
| CAPRIN2 | caprin family member 2 | 0.0436595 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0431904 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0431197 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0416765 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0413398 |
| AHNAK | AHNAK nucleoprotein | 0.0401291 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.039494 |
| CD9 | CD9 molecule | 0.0389108 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0380492 |
| PKM | pyruvate kinase, muscle | 0.0379773 |
| ANXA2 | annexin A2 | 0.0376992 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.037221 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0369488 |
| FAM13A | family with sequence similarity 13, member A | 0.0366917 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.036373 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0360986 |
| SUCO | SUN domain containing ossification factor | 0.0358679 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0357012 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.035691 |
| MED13L | mediator complex subunit 13-like | 0.0352764 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0349628 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0341644 |
| NCKAP1 | NCK-associated protein 1 | 0.033646 |
| ZNF292 | zinc finger protein 292 | 0.0336203 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.033594 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0335695 |
| SLK | STE20-like kinase | 0.0333156 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0332191 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.033034 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0330151 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0328401 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0327348 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0327115 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.032502 |
| VEZT | vezatin, adherens junctions transmembrane protein | 0.0324088 |
| NUP58 | nucleoporin 58 | 0.0323199 |
| FAT1 | FAT atypical cadherin 1 | 0.031509 |
| INSIG2 | insulin induced gene 2 | 0.0314722 |
| ANLN | anillin, actin binding protein | 0.0314265 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0313388 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0312237 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0311402 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0310923 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0303284 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0301557 |
| CTBP2 | C-terminal binding protein 2 | 0.0300222 |
| ARRDC3 | arrestin domain containing 3 | 0.029476 |
| CD47 | CD47 molecule | 0.0294264 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0291952 |
| SFTPA2 | surfactant protein A2 | 0.0290845 |
| RUNX1 | runt-related transcription factor 1 | 0.0289961 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0289807 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0289508 |
| DSTN | destrin (actin depolymerizing factor) | 0.0288379 |
| KCTD9 | potassium channel tetramerization domain containing 9 | 0.0287017 |
| ACVR1 | activin A receptor, type I | 0.0281842 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.0280935 |
| CCDC88A | coiled-coil domain containing 88A | 0.0279725 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0278823 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0277726 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.201607 |
| LAMB3 | laminin, beta 3 | -0.147048 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.135661 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.125054 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.107092 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.103122 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0727611 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0724566 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0715696 |
| KLK10 | kallikrein-related peptidase 10 | -0.0696187 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0594273 |
| RRBP1 | ribosome binding protein 1 | -0.057849 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0539771 |
| PRSS3 | protease, serine, 3 | -0.0487774 |
| LAMC2 | laminin, gamma 2 | -0.0473355 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0459824 |
| KLF6 | Kruppel-like factor 6 | -0.045723 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0450951 |
| RPS24 | ribosomal protein S24 | -0.0441411 |
| CLMP | CXADR-like membrane protein | -0.0437345 |
| FERMT1 | fermitin family member 1 | -0.042202 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0402783 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0396448 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0394128 |
| MIDN | midnolin | -0.0391082 |
| RPL35A | ribosomal protein L35a | -0.0360353 |
| VCL | vinculin | -0.0356357 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0353675 |
| SP100 | SP100 nuclear antigen | -0.0340523 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0337734 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0321689 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0314841 |
| TPM4 | tropomyosin 4 | -0.0311562 |
| THBD | thrombomodulin | -0.0311103 |
| RPS21 | ribosomal protein S21 | -0.0309845 |
| S100A4 | S100 calcium binding protein A4 | -0.0308265 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0300625 |
| RESF1 | retroelement silencing factor 1 | -0.0296101 |
| RIGI | RNA sensor RIG-I | -0.0293427 |
| RPL34 | ribosomal protein L34 | -0.0293337 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0290635 |
| SERINC5 | serine incorporator 5 | -0.0290459 |
| HMGA2 | high mobility group AT-hook 2 | -0.0281448 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0280033 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0275805 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0275027 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0274722 |
| TXNRD1 | thioredoxin reductase 1 | -0.0270187 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0263356 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0261846 |
| AK1 | adenylate kinase 1 | -0.0261517 |
| VCAN | versican | -0.0261054 |
| NPSR1 | neuropeptide S receptor 1 | -0.0244805 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.024314 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0242605 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0241252 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0240683 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0239741 |
| HDAC9 | histone deacetylase 9 | -0.0235762 |
| TMSB4X | thymosin beta 4, X-linked | -0.0233505 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0233231 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0233095 |
| IER3 | immediate early response 3 | -0.0231737 |
| EFNB2 | ephrin-B2 | -0.0230613 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0230469 |
| ARF1 | ADP-ribosylation factor 1 | -0.0228661 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0223595 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0222683 |
| LMO7 | LIM domain 7 | -0.0222574 |
| NPC1 | Niemann-Pick disease, type C1 | -0.022225 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0222244 |
| GNAS | GNAS complex locus | -0.0221648 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0220494 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0211341 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0207685 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0207473 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0206541 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0205043 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0204608 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0203144 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0202314 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0199842 |
| TGFA | transforming growth factor, alpha | -0.0198608 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0196409 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0196006 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0194224 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0191899 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0190716 |
| PLSCR1 | phospholipid scramblase 1 | -0.018898 |
| DENND2C | DENN/MADD domain containing 2C | -0.0188449 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0188238 |
| CAB39 | calcium binding protein 39 | -0.0188079 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0186735 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0184878 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0183636 |
| RASAL2 | RAS protein activator like 2 | -0.0183543 |
| MX2 | MX dynamin-like GTPase 2 | -0.0181481 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0180724 |
| RPL36A | ribosomal protein L36a | -0.0179147 |
| CD63 | CD63 molecule | -0.0178031 |
