| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEP250 | centrosomal protein 250kDa | 0.10778 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0790268 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0712112 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0580905 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0563184 |
| CLTC | clathrin, heavy chain (Hc) | 0.0552669 |
| PTK2 | protein tyrosine kinase 2 | 0.0537733 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0459112 |
| JMJD1C | jumonji domain containing 1C | 0.0441487 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0433805 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0429701 |
| GRB10 | growth factor receptor-bound protein 10 | 0.042151 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0385059 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0384169 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.038126 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0355262 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0345482 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0334037 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0327998 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0319397 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0312811 |
| ANXA2 | annexin A2 | 0.0311829 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0311155 |
| EFNA5 | ephrin-A5 | 0.0302799 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0301821 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.029877 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0296033 |
| LASP1 | LIM and SH3 protein 1 | 0.0294656 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0293526 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0286183 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0285912 |
| MSI2 | musashi RNA-binding protein 2 | 0.0281677 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0273093 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0270173 |
| GATAD2B | GATA zinc finger domain containing 2B | 0.0265941 |
| SBF2 | SET binding factor 2 | 0.0259932 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.025875 |
| TC2N | tandem C2 domains, nuclear | 0.0257777 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.025482 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 0.0252659 |
| KIAA1217 | KIAA1217 | 0.024718 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.024349 |
| SETD5 | SET domain containing 5 | 0.0239113 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.023824 |
| TTC6 | tetratricopeptide repeat domain 6 | 0.023515 |
| ADAR | adenosine deaminase, RNA-specific | 0.0235094 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0234698 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0233741 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0232979 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0230446 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0225993 |
| RBM47 | RNA binding motif protein 47 | 0.0221186 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0221075 |
| USP34 | ubiquitin specific peptidase 34 | 0.0217994 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0217417 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0216365 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0214414 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0203927 |
| DENND1B | DENN/MADD domain containing 1B | 0.0203402 |
| KIF16B | kinesin family member 16B | 0.020245 |
| PRELID2 | PRELI domain containing 2 | 0.0201505 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0200806 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0198153 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0196772 |
| CTBP2 | C-terminal binding protein 2 | 0.0195186 |
| PTEN | phosphatase and tensin homolog | 0.0195005 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0194601 |
| PARD3 | par-3 family cell polarity regulator | 0.0193976 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0190416 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0187433 |
| RBPMS | RNA binding protein with multiple splicing | 0.0187003 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0186012 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0185897 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.0184733 |
| RAD51B | RAD51 paralog B | 0.0184192 |
| INTS6 | integrator complex subunit 6 | 0.0184157 |
| SEPTIN11 | septin 11 | 0.0183273 |
| CDK13 | cyclin-dependent kinase 13 | 0.0182443 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0181642 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0181601 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0181174 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0180875 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0179932 |
| FAM168A | family with sequence similarity 168, member A | 0.0176248 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0174636 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.017408 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0173337 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0172605 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | 0.0171921 |
| BBX | bobby sox homolog (Drosophila) | 0.0171788 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0171563 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0170646 |
| ENAH | enabled homolog (Drosophila) | 0.0170367 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0170156 |
| PLEC | plectin | 0.0169942 |
| KMT5B | lysine methyltransferase 5B | 0.0169542 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0167236 |
| AHCTF1 | AT hook containing transcription factor 1 | 0.0166659 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0166056 |
| TFRC | transferrin receptor | 0.0165668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.260898 |
| RPL19 | ribosomal protein L19 | -0.119571 |
| UBC | ubiquitin C | -0.0958716 |
| TMSB10 | thymosin beta 10 | -0.0854328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0825204 |
| MT2A | metallothionein 2A | -0.0814525 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0775246 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0706162 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0629381 |
| S100A9 | S100 calcium binding protein A9 | -0.055793 |
| ACTG1 | actin gamma 1 | -0.0531448 |
| AHNAK | AHNAK nucleoprotein | -0.0482794 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0474425 |
| CCNI | cyclin I | -0.0454519 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0452203 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0449437 |
| S100A8 | S100 calcium binding protein A8 | -0.0444118 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0439763 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0426938 |
| PTMA | prothymosin, alpha | -0.0415429 |
| SDC4 | syndecan 4 | -0.0407469 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0384415 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0383008 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0361317 |
| CDK12 | cyclin-dependent kinase 12 | -0.0361167 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0360796 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0353952 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0353504 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0327581 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0323696 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0323491 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0322252 |
| TMSB4X | thymosin beta 4, X-linked | -0.032146 |
| RPS19 | ribosomal protein S19 | -0.0320692 |
| RPL32 | ribosomal protein L32 | -0.0314826 |
| S100A6 | S100 calcium binding protein A6 | -0.0302052 |
| IER3 | immediate early response 3 | -0.0295874 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0294449 |
| JUN | jun proto-oncogene | -0.0288522 |
| S100A7 | S100 calcium binding protein A7 | -0.0287638 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0282585 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0281251 |
| RPL8 | ribosomal protein L8 | -0.0272893 |
| GRHL1 | grainyhead-like 1 (Drosophila) | -0.0265091 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0255106 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0254137 |
| RPS3 | ribosomal protein S3 | -0.0250517 |
| KRT8 | keratin 8, type II | -0.0249232 |
| RPL34 | ribosomal protein L34 | -0.0244542 |
| PFDN4 | prefoldin subunit 4 | -0.0243223 |
| CBX3 | chromobox homolog 3 | -0.0239776 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0236833 |
| MT1X | metallothionein 1X | -0.0236206 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235729 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0230536 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.022861 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0224444 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0224135 |
| S100A10 | S100 calcium binding protein A10 | -0.0223536 |
| GOLGA4 | golgin A4 | -0.0220372 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0218619 |
| CCND1 | cyclin D1 | -0.0216543 |
| KRT7 | keratin 7, type II | -0.0215582 |
| CD63 | CD63 molecule | -0.021302 |
| LMNA | lamin A/C | -0.0211489 |
| MIEN1 | migration and invasion enhancer 1 | -0.0207156 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.020624 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0204778 |
| TENM2 | teneurin transmembrane protein 2 | -0.0203695 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0202913 |
| DUSP6 | dual specificity phosphatase 6 | -0.0201548 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0200602 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0198548 |
| UBE2Z | ubiquitin-conjugating enzyme E2Z | -0.019768 |
| RPL35A | ribosomal protein L35a | -0.0196058 |
| IPO7 | importin 7 | -0.0196018 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0195976 |
| CD164 | CD164 molecule, sialomucin | -0.0192637 |
| YBX3 | Y box binding protein 3 | -0.0192433 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0191907 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0190575 |
| RPS13 | ribosomal protein S13 | -0.018975 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0187767 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0185069 |
| RRBP1 | ribosome binding protein 1 | -0.0184579 |
| VMP1 | vacuole membrane protein 1 | -0.0184007 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0175351 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0171704 |
| HRNR | hornerin | -0.0169356 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0166315 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0165425 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0165143 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0163079 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0161237 |
| TXNRD1 | thioredoxin reductase 1 | -0.0159703 |
| FTL | ferritin, light polypeptide | -0.0159039 |
| DSG2 | desmoglein 2 | -0.0158488 |
| STK4 | serine/threonine kinase 4 | -0.0158159 |
| AREG | amphiregulin | -0.0157542 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0156633 |
