| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.336621 |
| LSAMP | limbic system-associated membrane protein | 0.147294 |
| PRKCA | protein kinase C, alpha | 0.110869 |
| VCL | vinculin | 0.110346 |
| FMN1 | formin 1 | 0.0994421 |
| NRG1 | neuregulin 1 | 0.0961596 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0942242 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0844999 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0783423 |
| MSI2 | musashi RNA-binding protein 2 | 0.0777284 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0764254 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0740091 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0698525 |
| LPIN1 | lipin 1 | 0.0679221 |
| TRIB2 | tribbles pseudokinase 2 | 0.0658208 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0648036 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.062647 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0569756 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0564497 |
| CADM2 | cell adhesion molecule 2 | 0.0561157 |
| AUTS2 | autism susceptibility candidate 2 | 0.0536585 |
| SEPTIN9 | septin 9 | 0.0511078 |
| ZNF804A | zinc finger protein 804A | 0.0508772 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0503688 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0495192 |
| FN1 | fibronectin 1 | 0.0495153 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0469452 |
| RNF213 | ring finger protein 213 | 0.0468724 |
| NREP | neuronal regeneration related protein | 0.0463535 |
| RAD51B | RAD51 paralog B | 0.0462569 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0452995 |
| DST | dystonin | 0.0444388 |
| DPH6 | diphthamine biosynthesis 6 | 0.0442938 |
| SYT1 | synaptotagmin I | 0.0442348 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0435118 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0421856 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0413192 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0400065 |
| TPM4 | tropomyosin 4 | 0.0395597 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0394935 |
| CANX | calnexin | 0.0393389 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0385989 |
| COL3A1 | collagen, type III, alpha 1 | 0.0377417 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0369514 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0366015 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0363449 |
| SMYD3 | SET and MYND domain containing 3 | 0.0356412 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0355829 |
| MEIS2 | Meis homeobox 2 | 0.0355068 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0354175 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0352764 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0351113 |
| CRH | corticotropin releasing hormone | 0.034992 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0348114 |
| VIM | vimentin | 0.0343872 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0342074 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0340577 |
| DNM3 | dynamin 3 | 0.0337461 |
| PCNX4 | pecanex 4 | 0.0335669 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0331956 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0331075 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.0330219 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0326141 |
| YEATS2 | YEATS domain containing 2 | 0.0323364 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.032299 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0321106 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0315392 |
| PRKCE | protein kinase C, epsilon | 0.0313658 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0313064 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0312306 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0311521 |
| AHNAK | AHNAK nucleoprotein | 0.0311333 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0307319 |
| ATRNL1 | attractin-like 1 | 0.0306516 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0304002 |
| GLI3 | GLI family zinc finger 3 | 0.0303456 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0295994 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0295256 |
| STK38L | serine/threonine kinase 38 like | 0.0293292 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0291441 |
| EXOC4 | exocyst complex component 4 | 0.0290257 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0289843 |
| GPC5 | glypican 5 | 0.0287846 |
| TENM4 | teneurin transmembrane protein 4 | 0.0287514 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0286309 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0285505 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0284962 |
| MTAP | methylthioadenosine phosphorylase | 0.0284743 |
| ZNF609 | zinc finger protein 609 | 0.0274838 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0273435 |
| VMP1 | vacuole membrane protein 1 | 0.0273021 |
| NBEA | neurobeachin | 0.0268341 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0267857 |
| ANGPT1 | angiopoietin 1 | 0.0266544 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.026437 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0262 |
| KANTR | KDM5C adjacent non-coding transcript | 0.0256965 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0255104 |
| ACTN4 | actinin, alpha 4 | 0.0251505 |
| GPC6 | glypican 6 | 0.0250904 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.179307 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0884178 |
| COL1A1 | collagen, type I, alpha 1 | -0.0521816 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0506569 |
| RPL38 | ribosomal protein L38 | -0.0497711 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.047238 |
| PRRC2C | proline-rich coiled-coil 2C | -0.043554 |
| RPS6 | ribosomal protein S6 | -0.0426692 |
| GOLGA4 | golgin A4 | -0.0387147 |
| TMSB10 | thymosin beta 10 | -0.0384262 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0383029 |
| RPL7A | ribosomal protein L7a | -0.0339599 |
| RPL35A | ribosomal protein L35a | -0.0338987 |
| RUNX1 | runt-related transcription factor 1 | -0.0335753 |
| RPLP1 | ribosomal protein, large, P1 | -0.0333803 |
| MTDH | metadherin | -0.0326835 |
| RPS2 | ribosomal protein S2 | -0.0318373 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0302184 |
| RPS25 | ribosomal protein S25 | -0.0301867 |
| PHIP | pleckstrin homology domain interacting protein | -0.0299449 |
| RTN4 | reticulon 4 | -0.0297028 |
| FTL | ferritin, light polypeptide | -0.0295653 |
| B2M | beta-2-microglobulin | -0.0294067 |
| RPS12 | ribosomal protein S12 | -0.0290114 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0285543 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0281817 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.0277528 |
| RPL36 | ribosomal protein L36 | -0.0276961 |
| RPS3 | ribosomal protein S3 | -0.0274558 |
| PLAT | plasminogen activator, tissue | -0.0274182 |
| RPL19 | ribosomal protein L19 | -0.0270566 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0268048 |
| CDC27 | cell division cycle 27 | -0.0262021 |
| GLG1 | golgi glycoprotein 1 | -0.0260917 |
| CLINT1 | clathrin interactor 1 | -0.0257931 |
| ZNF292 | zinc finger protein 292 | -0.0257133 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0255469 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0254743 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0241555 |
| SRP54 | signal recognition particle 54kDa | -0.0239655 |
| PHF21A | PHD finger protein 21A | -0.0238293 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0235517 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.0233341 |
| PCBP2 | poly(rC) binding protein 2 | -0.0227097 |
| S100A6 | S100 calcium binding protein A6 | -0.0226144 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0221286 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0221133 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0219871 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0211496 |
| MED13 | mediator complex subunit 13 | -0.0210298 |
| RPS14 | ribosomal protein S14 | -0.0209797 |
| RLF | rearranged L-myc fusion | -0.020902 |
| PCM1 | pericentriolar material 1 | -0.0208685 |
| RPL12 | ribosomal protein L12 | -0.0208526 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0208159 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0205762 |
| ACTG1 | actin gamma 1 | -0.0205602 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0205546 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.0201705 |
| LYST | lysosomal trafficking regulator | -0.020159 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0200213 |
| SBF2 | SET binding factor 2 | -0.0197718 |
| SON | SON DNA binding protein | -0.0197425 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0196429 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0195491 |
| MEF2A | myocyte enhancer factor 2A | -0.0195458 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | -0.0195327 |
| RPS19 | ribosomal protein S19 | -0.0194289 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0193797 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0190584 |
| LMNA | lamin A/C | -0.0189761 |
| RPS16 | ribosomal protein S16 | -0.0188641 |
| PRR11 | proline rich 11 | -0.0188322 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0186615 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0186196 |
| RPL34 | ribosomal protein L34 | -0.0185529 |
| CBFB | core-binding factor, beta subunit | -0.0184269 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0183299 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0183231 |
| STC1 | stanniocalcin 1 | -0.0178974 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0177391 |
| CBX3 | chromobox homolog 3 | -0.0176047 |
| GDF15 | growth differentiation factor 15 | -0.0175721 |
| RBM25 | RNA binding motif protein 25 | -0.0174615 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | -0.0174432 |
| CABIN1 | calcineurin binding protein 1 | -0.0174038 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0173657 |
| H3-3B | H3.3 histone B | -0.0173581 |
| CCNL1 | cyclin L1 | -0.017325 |
| USP32 | ubiquitin specific peptidase 32 | -0.0173189 |
| RPL28 | ribosomal protein L28 | -0.0172442 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0172298 |
| ANGPTL4 | angiopoietin-like 4 | -0.0171853 |
| H1-4 | H1.4 linker histone, cluster member | -0.0170233 |
| MCFD2 | multiple coagulation factor deficiency 2 | -0.0169753 |
| TP53 | tumor protein p53 | -0.0168736 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0167851 |
| S100A9 | S100 calcium binding protein A9 | -0.0167396 |
| XPO1 | exportin 1 | -0.0166934 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.0166065 |
