| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.117377 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.117065 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0856352 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0677488 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0629478 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0560411 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0549576 |
| EFNB2 | ephrin-B2 | 0.0545673 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0446692 |
| CANX | calnexin | 0.0444631 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0419097 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0418053 |
| RUNX1 | runt-related transcription factor 1 | 0.0414978 |
| PHF3 | PHD finger protein 3 | 0.0402511 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0384062 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0381386 |
| EHF | ets homologous factor | 0.0377923 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0369878 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.036923 |
| GOLGB1 | golgin B1 | 0.0362068 |
| SMAD3 | SMAD family member 3 | 0.035496 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0348837 |
| RNF43 | ring finger protein 43 | 0.0332505 |
| SEC24D | SEC24 family member D | 0.0331197 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0320005 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0316957 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0307005 |
| MEIS2 | Meis homeobox 2 | 0.03048 |
| H1-0 | H1.0 linker histone | 0.0303564 |
| RBM39 | RNA binding motif protein 39 | 0.0299092 |
| FAT1 | FAT atypical cadherin 1 | 0.0292372 |
| PRELID2 | PRELI domain containing 2 | 0.0287964 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0284217 |
| KIF16B | kinesin family member 16B | 0.0281642 |
| INTS6 | integrator complex subunit 6 | 0.0280776 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0279819 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0273557 |
| AFF1 | AF4/FMR2 family, member 1 | 0.027345 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0273145 |
| NDRG1 | N-myc downstream regulated 1 | 0.0272151 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0271555 |
| COG6 | component of oligomeric golgi complex 6 | 0.0266618 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0266425 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0264228 |
| DST | dystonin | 0.0263899 |
| IFNGR1 | interferon gamma receptor 1 | 0.0262241 |
| UBL3 | ubiquitin-like 3 | 0.0261845 |
| SQSTM1 | sequestosome 1 | 0.026081 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.025627 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0253886 |
| SUCO | SUN domain containing ossification factor | 0.0247392 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0243164 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.024293 |
| TC2N | tandem C2 domains, nuclear | 0.0241879 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0240831 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0239084 |
| HDLBP | high density lipoprotein binding protein | 0.023447 |
| AHI1 | Abelson helper integration site 1 | 0.023304 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0231184 |
| NCKAP5 | NCK-associated protein 5 | 0.0228722 |
| ANXA2 | annexin A2 | 0.0226845 |
| DSPP | dentin sialophosphoprotein | 0.0226688 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0226061 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0224185 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.022271 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0222519 |
| OGA | O-GlcNAcase | 0.0222066 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0221103 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0218717 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.02185 |
| CMIP | c-Maf inducing protein | 0.0217821 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0217186 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0216855 |
| FNIP1 | folliculin interacting protein 1 | 0.0216326 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0214641 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0209729 |
| ARRDC3 | arrestin domain containing 3 | 0.0208104 |
| CDHR2 | cadherin-related family member 2 | 0.0205172 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 0.0204427 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.020381 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0202714 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0201801 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0200934 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0197486 |
| CALU | calumenin | 0.0196396 |
| RNF149 | ring finger protein 149 | 0.0195657 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0193822 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0192428 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0192187 |
| AHNAK | AHNAK nucleoprotein | 0.0191012 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0189852 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.0188982 |
| ABHD2 | abhydrolase domain containing 2 | 0.0188638 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0188429 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0187816 |
| EZR | ezrin | 0.0187654 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0186102 |
| TUFT1 | tuftelin 1 | 0.0185531 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0185022 |
| STK24 | serine/threonine kinase 24 | 0.018275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | -0.165233 |
| LYZ | lysozyme | -0.138972 |
| B2M | beta-2-microglobulin | -0.136508 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.132665 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.115938 |
| PTMA | prothymosin, alpha | -0.0891458 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0838689 |
| SP100 | SP100 nuclear antigen | -0.0820053 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0771715 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0753506 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0724627 |
| VCL | vinculin | -0.0722023 |
| FTL | ferritin, light polypeptide | -0.0721396 |
| MX2 | MX dynamin-like GTPase 2 | -0.068657 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0683389 |
| RIGI | RNA sensor RIG-I | -0.0672048 |
| HLA-B | major histocompatibility complex, class I, B | -0.0669728 |
| MX1 | MX dynamin-like GTPase 1 | -0.0663472 |
| TMSB10 | thymosin beta 10 | -0.0658348 |
| RPL35A | ribosomal protein L35a | -0.064058 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.063599 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0623921 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0581086 |
| RNF213 | ring finger protein 213 | -0.0575515 |
| RPS6 | ribosomal protein S6 | -0.0544868 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0540159 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0529948 |
| TMC5 | transmembrane channel-like 5 | -0.0528217 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.051942 |
| RPL23 | ribosomal protein L23 | -0.0517213 |
| NPSR1 | neuropeptide S receptor 1 | -0.0507504 |
| XAF1 | XIAP associated factor 1 | -0.0487577 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0479866 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0445865 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0433942 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0430062 |
| ACTG1 | actin gamma 1 | -0.0425204 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.04194 |
| HLA-A | major histocompatibility complex, class I, A | -0.040551 |
| PKM | pyruvate kinase, muscle | -0.0402441 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.039298 |
| RPL34 | ribosomal protein L34 | -0.0370545 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0368821 |
| MT2A | metallothionein 2A | -0.0367363 |
| RPS19 | ribosomal protein S19 | -0.0367339 |
| PMP22 | peripheral myelin protein 22 | -0.0367191 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0364676 |
| RPS8 | ribosomal protein S8 | -0.036296 |
| RPL31 | ribosomal protein L31 | -0.0362579 |
| JUN | jun proto-oncogene | -0.0362377 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0353779 |
| ATP11A | ATPase, class VI, type 11A | -0.0351195 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0350908 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0348605 |
| RPS12 | ribosomal protein S12 | -0.0336962 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0335802 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0331001 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0329113 |
| RPS29 | ribosomal protein S29 | -0.0327993 |
| RPS27 | ribosomal protein S27 | -0.0325804 |
| RPS24 | ribosomal protein S24 | -0.0323564 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0322259 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0321606 |
| POTEF | POTE ankyrin domain family, member F | -0.031968 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0316145 |
| RPLP1 | ribosomal protein, large, P1 | -0.0306498 |
| EGR1 | early growth response 1 | -0.0305381 |
| EPHB2 | EPH receptor B2 | -0.0304545 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0301315 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0297808 |
| PLSCR1 | phospholipid scramblase 1 | -0.0293598 |
| RPS3 | ribosomal protein S3 | -0.0290428 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0288782 |
| RPL37A | ribosomal protein L37a | -0.0288683 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0288045 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0286612 |
| SSH2 | slingshot protein phosphatase 2 | -0.0281067 |
| RPL36A | ribosomal protein L36a | -0.0278041 |
| RPL37 | ribosomal protein L37 | -0.0274119 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0271084 |
| RPL26 | ribosomal protein L26 | -0.0270445 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0269451 |
| MUC20 | mucin 20, cell surface associated | -0.026865 |
| CST3 | cystatin C | -0.0267536 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0265637 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0264444 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0264242 |
| ETV6 | ets variant 6 | -0.0260301 |
| TNS4 | tensin 4 | -0.0257442 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0252827 |
| RPL28 | ribosomal protein L28 | -0.0252641 |
| RPL11 | ribosomal protein L11 | -0.0250114 |
| RPL19 | ribosomal protein L19 | -0.024924 |
| S100P | S100 calcium binding protein P | -0.0249121 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0247003 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0245734 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243613 |
| RPS17 | ribosomal protein S17 | -0.0243455 |
| RPL9 | ribosomal protein L9 | -0.024342 |
| LIMA1 | LIM domain and actin binding 1 | -0.0241994 |
