| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109168 |
| COL6A3 | collagen, type VI, alpha 3 | 0.103817 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0904328 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0820628 |
| CANX | calnexin | 0.0786798 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0658644 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0576194 |
| EGFR | epidermal growth factor receptor | 0.0567203 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0533289 |
| SMAD3 | SMAD family member 3 | 0.0529531 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0500788 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0480612 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0474255 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0439149 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0425565 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0418117 |
| ANKRD17 | ankyrin repeat domain 17 | 0.04123 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0395214 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0386662 |
| GOLGB1 | golgin B1 | 0.0373148 |
| ATP13A3 | ATPase type 13A3 | 0.0372 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0366623 |
| FOXJ3 | forkhead box J3 | 0.0357901 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0353725 |
| MSN | moesin | 0.0351202 |
| FAM13A | family with sequence similarity 13, member A | 0.0337278 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0334241 |
| GOLGA4 | golgin A4 | 0.0321411 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.031962 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0317612 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0316408 |
| OGA | O-GlcNAcase | 0.0313815 |
| GLIS3 | GLIS family zinc finger 3 | 0.0303316 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0301308 |
| TPM3 | tropomyosin 3 | 0.0300173 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0294257 |
| SNX13 | sorting nexin 13 | 0.0284629 |
| RLIM | ring finger protein, LIM domain interacting | 0.0282599 |
| TXNIP | thioredoxin interacting protein | 0.0282409 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0280308 |
| NDRG1 | N-myc downstream regulated 1 | 0.0277631 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0259403 |
| COG5 | component of oligomeric golgi complex 5 | 0.0257574 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0257278 |
| RBM39 | RNA binding motif protein 39 | 0.025584 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0253475 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0251397 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0248729 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0244948 |
| BRD2 | bromodomain containing 2 | 0.0243061 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.023721 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0234914 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0234512 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0234407 |
| METTL15 | methyltransferase like 15 | 0.0231457 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0230991 |
| SUCO | SUN domain containing ossification factor | 0.0229899 |
| YBX1 | Y box binding protein 1 | 0.0227378 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226763 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0226695 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0225704 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0225237 |
| ANXA2 | annexin A2 | 0.0224764 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0224037 |
| HELZ | helicase with zinc finger | 0.0223915 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0220777 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0220301 |
| ANXA5 | annexin A5 | 0.0219972 |
| CADM1 | cell adhesion molecule 1 | 0.0219885 |
| COPA | coatomer protein complex, subunit alpha | 0.0219321 |
| PKM | pyruvate kinase, muscle | 0.0218755 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0216913 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0216896 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0216584 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0216046 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0215624 |
| TLN1 | talin 1 | 0.0215598 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0215261 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0214493 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0213241 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0212048 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0211728 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.020838 |
| USP47 | ubiquitin specific peptidase 47 | 0.020827 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0206589 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0206506 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0205999 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0205938 |
| SRP54 | signal recognition particle 54kDa | 0.0205858 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0204465 |
| TFG | TRK-fused gene | 0.0203839 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0202577 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0201822 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0201668 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | 0.0201518 |
| ARHGAP10 | Rho GTPase activating protein 10 | 0.0201314 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0200335 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0200165 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0199939 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0199388 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.266525 |
| TMSB10 | thymosin beta 10 | -0.233614 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.196274 |
| VIM | vimentin | -0.136141 |
| HLA-B | major histocompatibility complex, class I, B | -0.105205 |
| MT2A | metallothionein 2A | -0.104472 |
| B2M | beta-2-microglobulin | -0.101645 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0974187 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0969867 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0880255 |
| NLGN1 | neuroligin 1 | -0.076999 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0744913 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0721213 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0696379 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0658939 |
| IGF2 | insulin-like growth factor 2 | -0.0614897 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0599947 |
| FN1 | fibronectin 1 | -0.0555839 |
| CALD1 | caldesmon 1 | -0.0539318 |
| ASPH | aspartate beta-hydroxylase | -0.0537016 |
| RPS6 | ribosomal protein S6 | -0.0504023 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0500288 |
| RPL35A | ribosomal protein L35a | -0.0491292 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0457892 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0456346 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.045205 |
| CLMP | CXADR-like membrane protein | -0.0424712 |
| EGR1 | early growth response 1 | -0.0423104 |
| TPM4 | tropomyosin 4 | -0.0415279 |
| HIP1 | huntingtin interacting protein 1 | -0.0414116 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0401384 |
| S100A10 | S100 calcium binding protein A10 | -0.03912 |
| PRSS23 | protease, serine, 23 | -0.0388522 |
| S100A6 | S100 calcium binding protein A6 | -0.0380148 |
| HLA-A | major histocompatibility complex, class I, A | -0.0378347 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0377673 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0371633 |
| NAV1 | neuron navigator 1 | -0.0366741 |
| H3-3B | H3.3 histone B | -0.0350297 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0349321 |
| RPS19 | ribosomal protein S19 | -0.0348758 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0342807 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0338868 |
| FTL | ferritin, light polypeptide | -0.0336102 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0333249 |
| CCND1 | cyclin D1 | -0.0332084 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0331751 |
| CBX3 | chromobox homolog 3 | -0.0330407 |
| AHNAK | AHNAK nucleoprotein | -0.0330107 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0328518 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0320201 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.031815 |
| ATXN1 | ataxin 1 | -0.0309825 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0306956 |
| ENO1 | enolase 1, (alpha) | -0.0306778 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0305125 |
| CUX1 | cut-like homeobox 1 | -0.030177 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0298982 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0297993 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0296213 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.029057 |
| HLA-C | major histocompatibility complex, class I, C | -0.0288354 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0285457 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0283871 |
| ACTG1 | actin gamma 1 | -0.0280259 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.0279844 |
| KYNU | kynureninase | -0.0277139 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0276009 |
| ASTN2 | astrotactin 2 | -0.0275777 |
| MT1X | metallothionein 1X | -0.0275629 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0273168 |
| VCL | vinculin | -0.0269552 |
| GNAS | GNAS complex locus | -0.026639 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | -0.0265987 |
| S100A9 | S100 calcium binding protein A9 | -0.0264146 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0262185 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0261198 |
| POTEF | POTE ankyrin domain family, member F | -0.025641 |
| RPL23 | ribosomal protein L23 | -0.0256272 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0253958 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0253286 |
| LMNA | lamin A/C | -0.0253147 |
| FBXO11 | F-box protein 11 | -0.0252338 |
| CAVIN1 | caveolae associated protein 1 | -0.024907 |
| PXDN | peroxidasin | -0.0247777 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0247326 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0247136 |
| NAV3 | neuron navigator 3 | -0.0244907 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0242913 |
| SDC4 | syndecan 4 | -0.0239178 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0238818 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.023872 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0236798 |
| FSTL1 | follistatin-like 1 | -0.0236095 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0235995 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0235709 |
| ITGA1 | integrin, alpha 1 | -0.0233597 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0233377 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0232718 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.023174 |
