| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.12401 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.119363 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.100288 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0911722 |
| APP | amyloid beta (A4) precursor protein | 0.0847915 |
| ITGB8 | integrin, beta 8 | 0.0756682 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0720535 |
| ANXA2 | annexin A2 | 0.0695239 |
| ZNF292 | zinc finger protein 292 | 0.0651312 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0625963 |
| ANLN | anillin, actin binding protein | 0.0567419 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0539377 |
| TXNRD1 | thioredoxin reductase 1 | 0.0536678 |
| SNX9 | sorting nexin 9 | 0.05351 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0532611 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0531932 |
| HELZ | helicase with zinc finger | 0.0531455 |
| OGA | O-GlcNAcase | 0.0531323 |
| NCKAP1 | NCK-associated protein 1 | 0.0513014 |
| AFDN | afadin, adherens junction formation factor | 0.0506399 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0496122 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0495517 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0487604 |
| ZNF148 | zinc finger protein 148 | 0.0486942 |
| ANKRD36 | ankyrin repeat domain 36 | 0.047541 |
| SBF2 | SET binding factor 2 | 0.0473611 |
| CANX | calnexin | 0.0472516 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0469356 |
| SETD5 | SET domain containing 5 | 0.0468195 |
| RNF145 | ring finger protein 145 | 0.0468131 |
| RTN4 | reticulon 4 | 0.044918 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0447748 |
| PCBP2 | poly(rC) binding protein 2 | 0.0431761 |
| GOLGA4 | golgin A4 | 0.0425497 |
| YEATS2 | YEATS domain containing 2 | 0.0422101 |
| PTK2 | protein tyrosine kinase 2 | 0.041273 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0405623 |
| MATR3 | matrin 3 | 0.0404022 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.04018 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0401091 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0394871 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0394557 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0387943 |
| DIAPH1 | diaphanous-related formin 1 | 0.0384921 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0381946 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.03787 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0377211 |
| PAX8 | paired box 8 | 0.0373848 |
| XPO1 | exportin 1 | 0.0372812 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0372203 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0353441 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0351664 |
| NUP58 | nucleoporin 58 | 0.0347737 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0345417 |
| SLMAP | sarcolemma associated protein | 0.0344943 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0340183 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0339788 |
| ZNF207 | zinc finger protein 207 | 0.0339781 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0337988 |
| PLEC | plectin | 0.0336873 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0336199 |
| SLTM | SAFB-like, transcription modulator | 0.0335906 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0334164 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0333643 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0332787 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0332483 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0329985 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0329981 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0328951 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0328801 |
| RBM39 | RNA binding motif protein 39 | 0.0327666 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0326941 |
| CCNL1 | cyclin L1 | 0.0326376 |
| PGK1 | phosphoglycerate kinase 1 | 0.0323868 |
| JMJD1C | jumonji domain containing 1C | 0.0323293 |
| TFG | TRK-fused gene | 0.0322283 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0322009 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0321527 |
| SMAD3 | SMAD family member 3 | 0.0320832 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0319728 |
| RLF | rearranged L-myc fusion | 0.0319599 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0318218 |
| FLNB | filamin B, beta | 0.0313282 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0311619 |
| SEPTIN9 | septin 9 | 0.0307772 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0307512 |
| PDS5B | PDS5 cohesin associated factor B | 0.0307447 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0305283 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0302116 |
| NKTR | natural killer cell triggering receptor | 0.0300856 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | 0.0299197 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0298442 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0298065 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0297262 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0296847 |
| ACTN4 | actinin, alpha 4 | 0.0296685 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0295922 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0295853 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0294311 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.029419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.18025 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0959118 |
| MT2A | metallothionein 2A | -0.0880947 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.076293 |
| RPL35A | ribosomal protein L35a | -0.0734998 |
| RPL31 | ribosomal protein L31 | -0.0619705 |
| FTL | ferritin, light polypeptide | -0.0603423 |
| RPS6 | ribosomal protein S6 | -0.0573887 |
| RPS19 | ribosomal protein S19 | -0.0568683 |
| RPL23 | ribosomal protein L23 | -0.0547664 |
| RPS12 | ribosomal protein S12 | -0.0541611 |
| RPL37A | ribosomal protein L37a | -0.0487853 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0456996 |
| HMGA2 | high mobility group AT-hook 2 | -0.0410456 |
| INTS6 | integrator complex subunit 6 | -0.0388814 |
| RPS3 | ribosomal protein S3 | -0.0387271 |
| RPS27A | ribosomal protein S27a | -0.0382607 |
| RPL7A | ribosomal protein L7a | -0.0374523 |
| RPS17 | ribosomal protein S17 | -0.0370838 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0365583 |
| RPS24 | ribosomal protein S24 | -0.0341458 |
| RPS14 | ribosomal protein S14 | -0.0332629 |
| RPL28 | ribosomal protein L28 | -0.0325971 |
| ACTG1 | actin gamma 1 | -0.0323672 |
| RPS8 | ribosomal protein S8 | -0.0315701 |
| NDRG1 | N-myc downstream regulated 1 | -0.0314413 |
| RPL9 | ribosomal protein L9 | -0.0299001 |
| RPLP2 | ribosomal protein, large, P2 | -0.0283672 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0277843 |
| ATF4 | activating transcription factor 4 | -0.0276911 |
| RPS25 | ribosomal protein S25 | -0.0259483 |
| FHIT | fragile histidine triad | -0.0258053 |
| RACK1 | receptor for activated C kinase 1 | -0.0255922 |
| CCDC138 | coiled-coil domain containing 138 | -0.0251434 |
| RPLP1 | ribosomal protein, large, P1 | -0.0242871 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0239049 |
| RPS4X | ribosomal protein S4, X-linked | -0.0238822 |
| RPL36 | ribosomal protein L36 | -0.0237979 |
| RPL12 | ribosomal protein L12 | -0.0233053 |
| RPS29 | ribosomal protein S29 | -0.0228904 |
| RPL34 | ribosomal protein L34 | -0.0227491 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0226416 |
| KRT86 | keratin 86, type II | -0.0223815 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0221712 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0220511 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0220074 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0217686 |
| RAD51B | RAD51 paralog B | -0.0216137 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0215079 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0211312 |
| RPL26 | ribosomal protein L26 | -0.0209539 |
| RPL11 | ribosomal protein L11 | -0.0209455 |
| S100A10 | S100 calcium binding protein A10 | -0.0206711 |
| ASPH | aspartate beta-hydroxylase | -0.0206276 |
| RPL4 | ribosomal protein L4 | -0.0205422 |
| PTMA | prothymosin, alpha | -0.0203299 |
| GNAS | GNAS complex locus | -0.0202788 |
| LAMA4 | laminin, alpha 4 | -0.0201225 |
| RPL32 | ribosomal protein L32 | -0.0200616 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0195751 |
| RPL27 | ribosomal protein L27 | -0.0193738 |
| RPL19 | ribosomal protein L19 | -0.0192193 |
| HMGB1 | high mobility group box 1 | -0.0189934 |
| RPL5 | ribosomal protein L5 | -0.0189736 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0189321 |
| LAMB3 | laminin, beta 3 | -0.0188937 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0186464 |
| RPL38 | ribosomal protein L38 | -0.0186032 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0184058 |
| SPATA13 | spermatogenesis associated 13 | -0.0184054 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0178626 |
| LRRC23 | leucine rich repeat containing 23 | -0.0178368 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0177925 |
| RPS16 | ribosomal protein S16 | -0.0174553 |
| PRKCA | protein kinase C, alpha | -0.0173555 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.017251 |
| RPS10 | ribosomal protein S10 | -0.0169207 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0167802 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.016564 |
| RPL36A | ribosomal protein L36a | -0.0165324 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0164063 |
| EGFR | epidermal growth factor receptor | -0.0162174 |
| RPL35 | ribosomal protein L35 | -0.0161195 |
| RPL18 | ribosomal protein L18 | -0.0159357 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0159042 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0157546 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0157177 |
| UBAP2 | ubiquitin associated protein 2 | -0.0155085 |
| EHBP1 | EH domain binding protein 1 | -0.0154287 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0153402 |
| NABP1 | nucleic acid binding protein 1 | -0.0151525 |
| S100A11 | S100 calcium binding protein A11 | -0.015127 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0150976 |
| DENND1A | DENN/MADD domain containing 1A | -0.0149925 |
| CD44 | CD44 molecule (Indian blood group) | -0.0148656 |
| RPL15 | ribosomal protein L15 | -0.0148055 |
| RPL37 | ribosomal protein L37 | -0.0146708 |
| MTAP | methylthioadenosine phosphorylase | -0.0145083 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0142784 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0141348 |
