| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.283308 |
| VIM | vimentin | 0.21808 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.195305 |
| COL6A3 | collagen, type VI, alpha 3 | 0.113741 |
| COL5A1 | collagen, type V, alpha 1 | 0.10571 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.102615 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0769224 |
| ANXA2 | annexin A2 | 0.0736065 |
| ENO1 | enolase 1, (alpha) | 0.0711136 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0663874 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0636552 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0629064 |
| GLIS3 | GLIS family zinc finger 3 | 0.0600366 |
| FLNB | filamin B, beta | 0.0582942 |
| SEPTIN9 | septin 9 | 0.0540681 |
| PLEC | plectin | 0.0533507 |
| NAV2 | neuron navigator 2 | 0.050988 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0502618 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0459638 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.044669 |
| RPL37A | ribosomal protein L37a | 0.0436402 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0432307 |
| PDE10A | phosphodiesterase 10A | 0.0409804 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0405602 |
| NAV1 | neuron navigator 1 | 0.0402742 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.039806 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0389404 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0388649 |
| CD109 | CD109 molecule | 0.0386464 |
| MT2A | metallothionein 2A | 0.0383775 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0381143 |
| OGA | O-GlcNAcase | 0.0379062 |
| L1CAM | L1 cell adhesion molecule | 0.0377876 |
| DST | dystonin | 0.0371622 |
| TPM4 | tropomyosin 4 | 0.0370072 |
| FLNA | filamin A, alpha | 0.035374 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0348822 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0347833 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0346044 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0345095 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0332923 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0332566 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0330508 |
| RPS12 | ribosomal protein S12 | 0.0322437 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0321721 |
| AHNAK | AHNAK nucleoprotein | 0.0321291 |
| ZNF148 | zinc finger protein 148 | 0.0320231 |
| RRM2 | ribonucleotide reductase M2 | 0.0319668 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0319595 |
| SETD5 | SET domain containing 5 | 0.0316673 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0311761 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0310266 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0307796 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.030763 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0303661 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0301776 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0301595 |
| GRB10 | growth factor receptor-bound protein 10 | 0.029853 |
| SBF2 | SET binding factor 2 | 0.0296997 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0293461 |
| TENM2 | teneurin transmembrane protein 2 | 0.0292709 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0291388 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0288153 |
| AFDN | afadin, adherens junction formation factor | 0.0283863 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0283691 |
| TPI1 | triosephosphate isomerase 1 | 0.0281488 |
| G0S2 | G0/G1 switch 2 | 0.0275082 |
| EFNA5 | ephrin-A5 | 0.0274228 |
| GANAB | glucosidase, alpha; neutral AB | 0.0273003 |
| CANX | calnexin | 0.0270638 |
| DIAPH2 | diaphanous-related formin 2 | 0.0269346 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0265626 |
| PCBP2 | poly(rC) binding protein 2 | 0.0261819 |
| ZNF638 | zinc finger protein 638 | 0.0258429 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.025836 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0256177 |
| TPM3 | tropomyosin 3 | 0.0255265 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0253883 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0253167 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0250476 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0249658 |
| CENPF | centromere protein F, 350/400kDa | 0.0248762 |
| SMAD3 | SMAD family member 3 | 0.0247421 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0246497 |
| AXL | AXL receptor tyrosine kinase | 0.0246007 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0245143 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0242991 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0242789 |
| SP3 | Sp3 transcription factor | 0.0239615 |
| YEATS2 | YEATS domain containing 2 | 0.0238594 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0238429 |
| LDHA | lactate dehydrogenase A | 0.0233194 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.023284 |
| CMIP | c-Maf inducing protein | 0.0232788 |
| ETV6 | ets variant 6 | 0.0231961 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0230981 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0230666 |
| HLA-A | major histocompatibility complex, class I, A | 0.022846 |
| PGK1 | phosphoglycerate kinase 1 | 0.0227602 |
| VEGFA | vascular endothelial growth factor A | 0.0227024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.289912 |
| EGR1 | early growth response 1 | -0.130729 |
| TMSB10 | thymosin beta 10 | -0.123098 |
| EXT1 | exostosin glycosyltransferase 1 | -0.110417 |
| IER3 | immediate early response 3 | -0.0902698 |
| CD44 | CD44 molecule (Indian blood group) | -0.0882615 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0790281 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0742768 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0662618 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0633952 |
| NDRG1 | N-myc downstream regulated 1 | -0.0632534 |
| IL1B | interleukin 1, beta | -0.0598995 |
| IGF2 | insulin-like growth factor 2 | -0.0586762 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.053416 |
| ACTG1 | actin gamma 1 | -0.0510621 |
| IL11 | interleukin 11 | -0.0486473 |
| INHBA | inhibin, beta A | -0.0481124 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0478042 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0451051 |
| RPS19 | ribosomal protein S19 | -0.0441788 |
| DUSP6 | dual specificity phosphatase 6 | -0.0439442 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0436697 |
| RPS24 | ribosomal protein S24 | -0.043096 |
| ASPH | aspartate beta-hydroxylase | -0.0415717 |
| CAVIN1 | caveolae associated protein 1 | -0.0414307 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0399087 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0370907 |
| RPL35A | ribosomal protein L35a | -0.0367238 |
| RPL34 | ribosomal protein L34 | -0.0354346 |
| RRBP1 | ribosome binding protein 1 | -0.0338376 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0321754 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0315137 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0311611 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0306148 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302383 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.030142 |
| GOLGA4 | golgin A4 | -0.0287663 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0285308 |
| PTMA | prothymosin, alpha | -0.0282531 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0278111 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0277157 |
| RPL32 | ribosomal protein L32 | -0.0276522 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0274443 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0273926 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0263445 |
| SQSTM1 | sequestosome 1 | -0.0252005 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0251771 |
| HPCAL1 | hippocalcin-like 1 | -0.0250913 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0250012 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0249123 |
| ADM | adrenomedullin | -0.0248545 |
| POU2F2 | POU class 2 homeobox 2 | -0.0242072 |
| TMEM263 | transmembrane protein 263 | -0.023965 |
| COL1A1 | collagen, type I, alpha 1 | -0.0239519 |
| ASTN2 | astrotactin 2 | -0.0238425 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0237406 |
| HLA-B | major histocompatibility complex, class I, B | -0.0236456 |
| LRRC23 | leucine rich repeat containing 23 | -0.0223524 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0221909 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0218657 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0213712 |
| MT1X | metallothionein 1X | -0.0211854 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0211022 |
| RPS16 | ribosomal protein S16 | -0.0209306 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0206661 |
| MYO1D | myosin ID | -0.0203371 |
| FTL | ferritin, light polypeptide | -0.0203085 |
| FMN1 | formin 1 | -0.0201551 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.019834 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0197719 |
| ZNF292 | zinc finger protein 292 | -0.0189589 |
| CDCP1 | CUB domain containing protein 1 | -0.0189527 |
| RPL15 | ribosomal protein L15 | -0.0187573 |
| SEC61G | Sec61 gamma subunit | -0.0186943 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0184868 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0183148 |
| RPL38 | ribosomal protein L38 | -0.0181916 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0181888 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0179119 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0178638 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.017817 |
| RBM39 | RNA binding motif protein 39 | -0.0177981 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0176653 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0175969 |
| RPL19 | ribosomal protein L19 | -0.0175776 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0173664 |
| CCND1 | cyclin D1 | -0.0171163 |
| RCOR1 | REST corepressor 1 | -0.017098 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.017088 |
| S100A10 | S100 calcium binding protein A10 | -0.0170401 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0170228 |
| RIOK3 | RIO kinase 3 | -0.0169737 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0169589 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0168916 |
| SHISA5 | shisa family member 5 | -0.016842 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0167213 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0165928 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0165906 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) | -0.0165569 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0165547 |
