| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.198673 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.12347 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0780174 |
| ITGA6 | integrin, alpha 6 | 0.0773904 |
| EZR | ezrin | 0.0764852 |
| ANXA2 | annexin A2 | 0.0740799 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0730035 |
| BCL2L1 | BCL2-like 1 | 0.0680391 |
| MYOF | myoferlin | 0.0642299 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0625331 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0623039 |
| OGA | O-GlcNAcase | 0.0603422 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0573048 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0568917 |
| TGM2 | transglutaminase 2 | 0.0557674 |
| PTK2 | protein tyrosine kinase 2 | 0.0547803 |
| CANX | calnexin | 0.0541967 |
| NDRG1 | N-myc downstream regulated 1 | 0.0539083 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0538331 |
| MEF2A | myocyte enhancer factor 2A | 0.0529618 |
| EMP1 | epithelial membrane protein 1 | 0.0527359 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0508027 |
| FOXO1 | forkhead box O1 | 0.049701 |
| NEK7 | NIMA-related kinase 7 | 0.0496839 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.048924 |
| CD44 | CD44 molecule (Indian blood group) | 0.0474107 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0473259 |
| AHNAK | AHNAK nucleoprotein | 0.0471495 |
| KRT17 | keratin 17, type I | 0.046333 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0463244 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0459315 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0458013 |
| PGK1 | phosphoglycerate kinase 1 | 0.0451586 |
| ANLN | anillin, actin binding protein | 0.0448287 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0448105 |
| PLEC | plectin | 0.0434701 |
| RBM39 | RNA binding motif protein 39 | 0.043379 |
| AOPEP | aminopeptidase O (putative) | 0.042956 |
| ENO1 | enolase 1, (alpha) | 0.0424991 |
| NRG1 | neuregulin 1 | 0.0424734 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0423581 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0420902 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0414118 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0407597 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0397288 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0395585 |
| PRELID2 | PRELI domain containing 2 | 0.0390528 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.038017 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0375576 |
| B2M | beta-2-microglobulin | 0.0375518 |
| RIN2 | Ras and Rab interactor 2 | 0.0372601 |
| SULF1 | sulfatase 1 | 0.0371198 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0369019 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0367862 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0367144 |
| CUL4B | cullin 4B | 0.0361162 |
| MSN | moesin | 0.036047 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0358723 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0358529 |
| EFHD2 | EF-hand domain family, member D2 | 0.0354468 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0351461 |
| KRT6A | keratin 6A, type II | 0.0350554 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | 0.0348302 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0346564 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0346361 |
| ASPH | aspartate beta-hydroxylase | 0.034335 |
| CALU | calumenin | 0.0340868 |
| SLK | STE20-like kinase | 0.0339892 |
| TPM3 | tropomyosin 3 | 0.0338694 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0337012 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335239 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0332497 |
| DST | dystonin | 0.0330398 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.032444 |
| FNIP1 | folliculin interacting protein 1 | 0.0324242 |
| PODXL | podocalyxin-like | 0.0322776 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0322254 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0321602 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0319859 |
| SMAD3 | SMAD family member 3 | 0.0319269 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0318751 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0317179 |
| KIAA1217 | KIAA1217 | 0.0314642 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0313531 |
| APP | amyloid beta (A4) precursor protein | 0.0311226 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0310737 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0308726 |
| ARRDC3 | arrestin domain containing 3 | 0.0308097 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0306435 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0306225 |
| BLCAP | bladder cancer associated protein | 0.0305881 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0304239 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0302776 |
| CLU | clusterin | 0.0301252 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0299308 |
| YEATS2 | YEATS domain containing 2 | 0.0299038 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0294463 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0292555 |
| FOXP1 | forkhead box P1 | 0.0292465 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0291035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.106924 |
| RPS6 | ribosomal protein S6 | -0.0790439 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0658284 |
| INTS6 | integrator complex subunit 6 | -0.0649976 |
| TMSB10 | thymosin beta 10 | -0.0631525 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.059523 |
| SULF2 | sulfatase 2 | -0.0511555 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0475659 |
| RPL37A | ribosomal protein L37a | -0.0448111 |
| RPS19 | ribosomal protein S19 | -0.042858 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0414815 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0391512 |
| RPS21 | ribosomal protein S21 | -0.0384028 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0380071 |
| RPS8 | ribosomal protein S8 | -0.0376124 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0375198 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354852 |
| EGR1 | early growth response 1 | -0.0352854 |
| RPS3 | ribosomal protein S3 | -0.0350897 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0346648 |
| FTL | ferritin, light polypeptide | -0.0338934 |
| RPL23 | ribosomal protein L23 | -0.033168 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325249 |
| RAI14 | retinoic acid induced 14 | -0.0324942 |
| RPS25 | ribosomal protein S25 | -0.0316514 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0313131 |
| RPS24 | ribosomal protein S24 | -0.0303738 |
| S100A10 | S100 calcium binding protein A10 | -0.0300395 |
| RPL8 | ribosomal protein L8 | -0.0299454 |
| RPL35A | ribosomal protein L35a | -0.0290517 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0278153 |
| RPL31 | ribosomal protein L31 | -0.0273075 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0271694 |
| RPS14 | ribosomal protein S14 | -0.0258981 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0257996 |
| RPLP1 | ribosomal protein, large, P1 | -0.025781 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.025189 |
| ACTG1 | actin gamma 1 | -0.0244698 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0243054 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0241962 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0241715 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0239757 |
| SIK3 | SIK family kinase 3 | -0.0238682 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0236637 |
| ATF4 | activating transcription factor 4 | -0.0230771 |
| RPS13 | ribosomal protein S13 | -0.0229892 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.022687 |
| RPL34 | ribosomal protein L34 | -0.0224999 |
| SEC61G | Sec61 gamma subunit | -0.0214214 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0208086 |
| DUSP6 | dual specificity phosphatase 6 | -0.0207147 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0206232 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0202392 |
| RPL11 | ribosomal protein L11 | -0.0197853 |
| RPL28 | ribosomal protein L28 | -0.0196208 |
| THBD | thrombomodulin | -0.0194796 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0189854 |
| RPL36 | ribosomal protein L36 | -0.0189341 |
| RPL7A | ribosomal protein L7a | -0.0189068 |
| S100A9 | S100 calcium binding protein A9 | -0.0188904 |
| TENM4 | teneurin transmembrane protein 4 | -0.0188199 |
| ASTN2 | astrotactin 2 | -0.0186567 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0185262 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0185068 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0184541 |
| SYN3 | synapsin III | -0.0184459 |
| S100A11 | S100 calcium binding protein A11 | -0.0183662 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0183425 |
| RPL37 | ribosomal protein L37 | -0.017684 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0176503 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0175321 |
| KIAA1671 | KIAA1671 | -0.0175262 |
| RPL36A | ribosomal protein L36a | -0.0171027 |
| PURA | purine-rich element binding protein A | -0.0170701 |
| LMO7 | LIM domain 7 | -0.017054 |
| ADIRF | adipogenesis regulatory factor | -0.0168877 |
| HMGA1 | high mobility group AT-hook 1 | -0.0168344 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0167406 |
| RPS4X | ribosomal protein S4, X-linked | -0.0167296 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0167128 |
| TLE4 | transducin-like enhancer of split 4 | -0.0166428 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0162823 |
| CDK17 | cyclin-dependent kinase 17 | -0.0161807 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0160987 |
| CSTB | cystatin B (stefin B) | -0.0160879 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0157149 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0153681 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0153501 |
| ARF1 | ADP-ribosylation factor 1 | -0.015298 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.015175 |
| MT2A | metallothionein 2A | -0.0151126 |
| LRRC8A | leucine rich repeat containing 8 family, member A | -0.014994 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.014832 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0147941 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0147373 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.0146922 |
| RPL35 | ribosomal protein L35 | -0.0146593 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0146472 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0146429 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0145747 |
