| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.086701 |
| POTEF | POTE ankyrin domain family, member F | 0.0809477 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0792849 |
| B2M | beta-2-microglobulin | 0.0786518 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0780714 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.076178 |
| FLNB | filamin B, beta | 0.0705771 |
| CALR | calreticulin | 0.0633803 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0605159 |
| MSN | moesin | 0.0558093 |
| PKM | pyruvate kinase, muscle | 0.0538615 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0538249 |
| VEGFA | vascular endothelial growth factor A | 0.0524341 |
| PCBP2 | poly(rC) binding protein 2 | 0.0507247 |
| FN1 | fibronectin 1 | 0.0503434 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.048633 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0479817 |
| TPM3 | tropomyosin 3 | 0.0477433 |
| NAV2 | neuron navigator 2 | 0.0476703 |
| MT2A | metallothionein 2A | 0.0451713 |
| ENO1 | enolase 1, (alpha) | 0.0433764 |
| FNDC3B | fibronectin type III domain containing 3B | 0.04274 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0409648 |
| L1CAM | L1 cell adhesion molecule | 0.0395821 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0388566 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0383586 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0376028 |
| BRD2 | bromodomain containing 2 | 0.0373954 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0371735 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.036446 |
| NCOR2 | nuclear receptor corepressor 2 | 0.036062 |
| SET | SET nuclear proto-oncogene | 0.035885 |
| PTMA | prothymosin, alpha | 0.0357873 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0353721 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0352385 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0351926 |
| INTS6 | integrator complex subunit 6 | 0.0351741 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0349624 |
| RPS12 | ribosomal protein S12 | 0.0348575 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0339573 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0336209 |
| SEPTIN9 | septin 9 | 0.0335837 |
| ADM | adrenomedullin | 0.0334485 |
| SFTPA2 | surfactant protein A2 | 0.0309844 |
| STC2 | stanniocalcin 2 | 0.0303854 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0303683 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0300401 |
| HLA-A | major histocompatibility complex, class I, A | 0.0298045 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0297465 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0296526 |
| FOSL1 | FOS-like antigen 1 | 0.0295508 |
| PLIN2 | perilipin 2 | 0.0295109 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.029424 |
| ANXA1 | annexin A1 | 0.0294215 |
| MCL1 | myeloid cell leukemia 1 | 0.0293523 |
| RPL37A | ribosomal protein L37a | 0.0293454 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0292794 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0288801 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0284601 |
| RPS3 | ribosomal protein S3 | 0.028438 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0278554 |
| NUP58 | nucleoporin 58 | 0.027821 |
| FAM219A | family with sequence similarity 219, member A | 0.0277951 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0275957 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0275866 |
| CEP250 | centrosomal protein 250kDa | 0.0272397 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0267763 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.026573 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0265299 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0264774 |
| PLEC | plectin | 0.0263464 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0258109 |
| COL5A1 | collagen, type V, alpha 1 | 0.0252779 |
| ASPH | aspartate beta-hydroxylase | 0.0252251 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.025018 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0246374 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0245217 |
| DTNA | dystrobrevin, alpha | 0.0242742 |
| CCNL1 | cyclin L1 | 0.0239182 |
| YEATS2 | YEATS domain containing 2 | 0.0237074 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0235889 |
| DST | dystonin | 0.0227094 |
| DIPK2A | divergent protein kinase domain 2A | 0.0226327 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0225299 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0225163 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0223943 |
| PDE10A | phosphodiesterase 10A | 0.0222294 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0221077 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0219984 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0218427 |
| INSIG2 | insulin induced gene 2 | 0.0216144 |
| NOTCH2 | notch 2 | 0.021596 |
| RPL7 | ribosomal protein L7 | 0.0214745 |
| ARF4 | ADP-ribosylation factor 4 | 0.0214039 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0213428 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0213015 |
| YBX1 | Y box binding protein 1 | 0.0211059 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0209229 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0206396 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0206164 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | -0.113965 |
| MT1X | metallothionein 1X | -0.10997 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105584 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.101666 |
| CD44 | CD44 molecule (Indian blood group) | -0.0880588 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0814987 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0790899 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0601159 |
| CAVIN1 | caveolae associated protein 1 | -0.0576261 |
| OSMR | oncostatin M receptor | -0.0483427 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0482553 |
| ZNF432 | zinc finger protein 432 | -0.0465279 |
| TXNRD1 | thioredoxin reductase 1 | -0.0461359 |
| AHNAK | AHNAK nucleoprotein | -0.0438953 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0434445 |
| ACTG1 | actin gamma 1 | -0.0425487 |
| HLA-C | major histocompatibility complex, class I, C | -0.0402172 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.037392 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0347399 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0339362 |
| IER3 | immediate early response 3 | -0.0329643 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0327021 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.03257 |
| DEK | DEK proto-oncogene | -0.0322631 |
| TMSB4X | thymosin beta 4, X-linked | -0.0320134 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0317967 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.03122 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0295207 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0288374 |
| PLSCR1 | phospholipid scramblase 1 | -0.0286889 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0286027 |
| RRBP1 | ribosome binding protein 1 | -0.0277115 |
| ARF1 | ADP-ribosylation factor 1 | -0.0270403 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0264928 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0260525 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0259502 |
| CCND1 | cyclin D1 | -0.0258008 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0251578 |
| LAMP1 | lysosomal-associated membrane protein 1 | -0.0249818 |
| PLCB4 | phospholipase C, beta 4 | -0.0247036 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0246018 |
| GLIS3 | GLIS family zinc finger 3 | -0.0239779 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0238163 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0238128 |
| TUBB | tubulin, beta class I | -0.0231674 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0229216 |
| EGR1 | early growth response 1 | -0.0228254 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0227793 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0225356 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0223814 |
| TMSB10 | thymosin beta 10 | -0.022225 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0215137 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0213585 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.021297 |
| LOX | lysyl oxidase | -0.0212532 |
| HMGB1 | high mobility group box 1 | -0.0210818 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0209414 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0204175 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0202577 |
| EMP1 | epithelial membrane protein 1 | -0.0202449 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0196687 |
| FUS | FUS RNA binding protein | -0.0196346 |
| NF1 | neurofibromin 1 | -0.0196268 |
| MORF4L2 | mortality factor 4 like 2 | -0.0194436 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.019272 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0192004 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0190825 |
| GOLGA3 | golgin A3 | -0.0188695 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0187396 |
| H1-4 | H1.4 linker histone, cluster member | -0.0185647 |
| POSTN | periostin, osteoblast specific factor | -0.0184547 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0181475 |
| TLK1 | tousled-like kinase 1 | -0.0179564 |
| ERBIN | erbb2 interacting protein | -0.0179029 |
| CBX3 | chromobox homolog 3 | -0.0178333 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.017744 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0176393 |
| CDK12 | cyclin-dependent kinase 12 | -0.0175736 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0175429 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0172908 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0172462 |
| COL12A1 | collagen, type XII, alpha 1 | -0.0169867 |
| GOLT1B | golgi transport 1B | -0.0169602 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0169262 |
| DIAPH3 | diaphanous-related formin 3 | -0.016839 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0167583 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0167351 |
| VCL | vinculin | -0.0166644 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0166234 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0166118 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0166105 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0164812 |
| STK4 | serine/threonine kinase 4 | -0.0164071 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0163852 |
| MTAP | methylthioadenosine phosphorylase | -0.0163839 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0163574 |
| RAB1B | RAB1B, member RAS oncogene family | -0.0163126 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0163095 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0162929 |
| ZNF43 | zinc finger protein 43 | -0.0160126 |
