| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DTNA | dystrobrevin, alpha | 0.162796 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0983343 |
| ASPH | aspartate beta-hydroxylase | 0.0896581 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0755547 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0748244 |
| NDRG1 | N-myc downstream regulated 1 | 0.0695482 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0664745 |
| ANXA2 | annexin A2 | 0.0624355 |
| USP15 | ubiquitin specific peptidase 15 | 0.0544893 |
| USP34 | ubiquitin specific peptidase 34 | 0.0544598 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0537326 |
| BRD2 | bromodomain containing 2 | 0.0510233 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0507115 |
| SMAP1 | small ArfGAP 1 | 0.0487764 |
| RASA2 | RAS p21 protein activator 2 | 0.0462611 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.046055 |
| PRKCE | protein kinase C, epsilon | 0.0458774 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0449464 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0439792 |
| OSMR | oncostatin M receptor | 0.0432125 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0413794 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0411767 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0410659 |
| LDHA | lactate dehydrogenase A | 0.0410596 |
| NBAS | neuroblastoma amplified sequence | 0.0393816 |
| TRIM44 | tripartite motif containing 44 | 0.0386133 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0385905 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0377162 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0374157 |
| PSPC1 | paraspeckle component 1 | 0.037353 |
| ARFGEF3 | ARFGEF family member 3 | 0.0373192 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0356349 |
| PKM | pyruvate kinase, muscle | 0.0353427 |
| FCHO2 | FCH domain only 2 | 0.0349047 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0346724 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0342566 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0336934 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0336929 |
| CANX | calnexin | 0.0334725 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0332426 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0332223 |
| RBM39 | RNA binding motif protein 39 | 0.032984 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0328982 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0327296 |
| NCKAP1 | NCK-associated protein 1 | 0.0325314 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0322879 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0315294 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0314498 |
| BPTF | bromodomain PHD finger transcription factor | 0.031395 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0311678 |
| TBC1D4 | TBC1 domain family, member 4 | 0.0307848 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0307019 |
| ATM | ATM serine/threonine kinase | 0.0305278 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0302542 |
| FN1 | fibronectin 1 | 0.0301708 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.0298732 |
| NOTCH2 | notch 2 | 0.0298547 |
| FNIP1 | folliculin interacting protein 1 | 0.0296323 |
| PTCHD4 | patched domain containing 4 | 0.0294283 |
| PAX3 | paired box 3 | 0.0294161 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0293557 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0293313 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0290148 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0286979 |
| ABHD5 | abhydrolase domain containing 5 | 0.0286684 |
| MED13L | mediator complex subunit 13-like | 0.0285683 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0285397 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.028445 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0282524 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0281326 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.027783 |
| SPAG9 | sperm associated antigen 9 | 0.0276289 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.027622 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0272266 |
| OGA | O-GlcNAcase | 0.0271462 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0270194 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0269443 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0268515 |
| NGLY1 | N-glycanase 1 | 0.0267668 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.026483 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0264202 |
| RAI14 | retinoic acid induced 14 | 0.0263573 |
| CEP85L | centrosomal protein 85kDa-like | 0.0262676 |
| PARD3 | par-3 family cell polarity regulator | 0.0259534 |
| FOCAD | focadhesin | 0.0257392 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0255263 |
| RUNX1 | runt-related transcription factor 1 | 0.0255007 |
| CREBBP | CREB binding protein | 0.0253313 |
| DGKH | diacylglycerol kinase, eta | 0.025254 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.025025 |
| PLEC | plectin | 0.024913 |
| PTK2 | protein tyrosine kinase 2 | 0.0247712 |
| EP400 | E1A binding protein p400 | 0.0247462 |
| RPL37A | ribosomal protein L37a | 0.0246226 |
| APP | amyloid beta (A4) precursor protein | 0.024457 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0243935 |
| CERT1 | ceramide transporter 1 | 0.0243158 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0242837 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0242825 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0240966 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.155028 |
| VIM | vimentin | -0.119698 |
| TMSB10 | thymosin beta 10 | -0.111384 |
| LSAMP | limbic system-associated membrane protein | -0.0677745 |
| EGR1 | early growth response 1 | -0.0605773 |
| RPS6 | ribosomal protein S6 | -0.0598373 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0554253 |
| NTM | neurotrimin | -0.0551861 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0517788 |
| FTL | ferritin, light polypeptide | -0.0509576 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0506038 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.050477 |
| RPS19 | ribosomal protein S19 | -0.0502702 |
| MT2A | metallothionein 2A | -0.0479274 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0440077 |
| KIAA1549L | KIAA1549-like | -0.042084 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0409418 |
| MMP12 | matrix metallopeptidase 12 | -0.0389016 |
| FOXP1 | forkhead box P1 | -0.0384847 |
| RTN4 | reticulon 4 | -0.0381419 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0368541 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0339836 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0333173 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0327849 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0326265 |
| CSTB | cystatin B (stefin B) | -0.0317371 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0308568 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0307993 |
| RPL8 | ribosomal protein L8 | -0.0306117 |
| CDH13 | cadherin 13 | -0.0300994 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0299111 |
| PFN1 | profilin 1 | -0.0290253 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0289264 |
| RPS4X | ribosomal protein S4, X-linked | -0.0285464 |
| H1-0 | H1.0 linker histone | -0.0279334 |
| RPL32 | ribosomal protein L32 | -0.0269176 |
| RPL12 | ribosomal protein L12 | -0.0268553 |
| TNNC1 | troponin C type 1 (slow) | -0.0267973 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.026319 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0255462 |
| CDK14 | cyclin-dependent kinase 14 | -0.0253237 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0245297 |
| RPL19 | ribosomal protein L19 | -0.0244744 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0244176 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239637 |
| INHBA | inhibin, beta A | -0.0236215 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0235477 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0234444 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0232748 |
| RPL18 | ribosomal protein L18 | -0.0228235 |
| IER3 | immediate early response 3 | -0.0226535 |
| RPL36 | ribosomal protein L36 | -0.0224112 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.022297 |
| CDK17 | cyclin-dependent kinase 17 | -0.022055 |
| JUN | jun proto-oncogene | -0.0219361 |
| ASTN2 | astrotactin 2 | -0.0216461 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0214071 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0212728 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0210729 |
| KLF6 | Kruppel-like factor 6 | -0.0207527 |
| RPS21 | ribosomal protein S21 | -0.0202859 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0198964 |
| CDK6 | cyclin-dependent kinase 6 | -0.0198112 |
| CUX1 | cut-like homeobox 1 | -0.0186132 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0185377 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0185002 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0183795 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0179324 |
| FOSL1 | FOS-like antigen 1 | -0.0177998 |
| HMGB1 | high mobility group box 1 | -0.0174713 |
| ETV6 | ets variant 6 | -0.0174311 |
| MEIS2 | Meis homeobox 2 | -0.0172244 |
| GPC6 | glypican 6 | -0.0171868 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0170301 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0170068 |
| TENM2 | teneurin transmembrane protein 2 | -0.0168912 |
| RPLP2 | ribosomal protein, large, P2 | -0.0168096 |
| RIGI | RNA sensor RIG-I | -0.016653 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0166518 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0166312 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0163364 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0163163 |
| RPL23 | ribosomal protein L23 | -0.0161945 |
| TXNIP | thioredoxin interacting protein | -0.0161643 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0159927 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0158986 |
| RPL36A | ribosomal protein L36a | -0.0158951 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0156694 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0156151 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0156098 |
| SDC4 | syndecan 4 | -0.0155222 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.015437 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0153279 |
| RPL35 | ribosomal protein L35 | -0.0152715 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0151691 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0151097 |
| RPLP1 | ribosomal protein, large, P1 | -0.0151018 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.014997 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.014964 |
| TPI1 | triosephosphate isomerase 1 | -0.0149228 |
