| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.17772 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.124897 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.1124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.109794 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.107425 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.106568 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0937044 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0822775 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0770034 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0763832 |
| RNF43 | ring finger protein 43 | 0.0713682 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0672683 |
| FAM13A | family with sequence similarity 13, member A | 0.0666467 |
| MED13L | mediator complex subunit 13-like | 0.0666313 |
| NDRG1 | N-myc downstream regulated 1 | 0.06188 |
| TRIM2 | tripartite motif containing 2 | 0.05837 |
| LDHA | lactate dehydrogenase A | 0.0581019 |
| PCBP2 | poly(rC) binding protein 2 | 0.0575275 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0545939 |
| OGA | O-GlcNAcase | 0.0540904 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0534298 |
| ITGA6 | integrin, alpha 6 | 0.0526063 |
| GOLGA4 | golgin A4 | 0.0523464 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0514037 |
| TXNIP | thioredoxin interacting protein | 0.0510812 |
| RNF145 | ring finger protein 145 | 0.051066 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0500168 |
| EREG | epiregulin | 0.049877 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0484539 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0484493 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0478738 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.047858 |
| DSPP | dentin sialophosphoprotein | 0.0476919 |
| CALR | calreticulin | 0.0476079 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0474935 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0464527 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0463466 |
| VEGFA | vascular endothelial growth factor A | 0.0462391 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0461634 |
| ANXA2 | annexin A2 | 0.0459921 |
| PTEN | phosphatase and tensin homolog | 0.0453751 |
| CANX | calnexin | 0.0450789 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0449228 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0445766 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0444121 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0438583 |
| NEBL | nebulette | 0.0435402 |
| LMO7 | LIM domain 7 | 0.0432963 |
| GPHN | gephyrin | 0.0414264 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0414115 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0409664 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0406368 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0396801 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0396429 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0395583 |
| PRELID2 | PRELI domain containing 2 | 0.0391982 |
| SETD5 | SET domain containing 5 | 0.0390123 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0389071 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0388839 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0388399 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0386521 |
| RBM39 | RNA binding motif protein 39 | 0.0382519 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0381997 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0374921 |
| COG5 | component of oligomeric golgi complex 5 | 0.0374846 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0369528 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.036571 |
| CADPS | Ca++-dependent secretion activator | 0.0365685 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0365293 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0360136 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0351404 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0350321 |
| PGK1 | phosphoglycerate kinase 1 | 0.0349296 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0344997 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0344027 |
| TFG | TRK-fused gene | 0.0336597 |
| COPA | coatomer protein complex, subunit alpha | 0.0336166 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0333088 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0330354 |
| PDZD8 | PDZ domain containing 8 | 0.0329321 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0326929 |
| CLTC | clathrin, heavy chain (Hc) | 0.0326879 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0323702 |
| MUC13 | mucin 13, cell surface associated | 0.032233 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0321386 |
| TNS4 | tensin 4 | 0.0321115 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0320603 |
| RREB1 | ras responsive element binding protein 1 | 0.0319077 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0315747 |
| EHF | ets homologous factor | 0.0313505 |
| ATXN1 | ataxin 1 | 0.0311094 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0309817 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0307408 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0306354 |
| YTHDC1 | YTH domain containing 1 | 0.0305549 |
| ETNK1 | ethanolamine kinase 1 | 0.0304916 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0303127 |
| ZNF148 | zinc finger protein 148 | 0.0300227 |
| PTMA | prothymosin, alpha | 0.0299718 |
| SUCO | SUN domain containing ossification factor | 0.029824 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.148723 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.148516 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.142472 |
| TMSB10 | thymosin beta 10 | -0.13651 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0725821 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0711882 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0697683 |
| S100A6 | S100 calcium binding protein A6 | -0.0587052 |
| ACTG1 | actin gamma 1 | -0.0567978 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0533896 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0496562 |
| RPS6 | ribosomal protein S6 | -0.0464581 |
| FTL | ferritin, light polypeptide | -0.0434553 |
| RPL35A | ribosomal protein L35a | -0.0433806 |
| TFF1 | trefoil factor 1 | -0.0406306 |
| IER3 | immediate early response 3 | -0.0403435 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0361789 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0354045 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0347622 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0329686 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0316018 |
| LAMA4 | laminin, alpha 4 | -0.0302266 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0302242 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0301519 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0297527 |
| TFF3 | trefoil factor 3 (intestinal) | -0.0289863 |
| RPL34 | ribosomal protein L34 | -0.0285564 |
| RPS19 | ribosomal protein S19 | -0.0273527 |
| EGFR | epidermal growth factor receptor | -0.0271364 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0265182 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0264956 |
| FERMT1 | fermitin family member 1 | -0.0261962 |
| CCND1 | cyclin D1 | -0.0255849 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0254431 |
| RPLP2 | ribosomal protein, large, P2 | -0.0253475 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0249612 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0247698 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241474 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0241176 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0239405 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0238156 |
| HMGB1 | high mobility group box 1 | -0.0235234 |
| MT2A | metallothionein 2A | -0.0234636 |
| EGR1 | early growth response 1 | -0.0213641 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.021317 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0209875 |
| FHIT | fragile histidine triad | -0.0205907 |
| RNF217 | ring finger protein 217 | -0.0205877 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0203855 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0202209 |
| LMNA | lamin A/C | -0.0202078 |
| SH3D19 | SH3 domain containing 19 | -0.0199223 |
| KLK10 | kallikrein-related peptidase 10 | -0.0199179 |
| RPL32 | ribosomal protein L32 | -0.019731 |
| RPS14 | ribosomal protein S14 | -0.0195854 |
| RPS21 | ribosomal protein S21 | -0.0195204 |
| RPS24 | ribosomal protein S24 | -0.0194002 |
| PCED1B | PC-esterase domain containing 1B | -0.0193188 |
| FRMD5 | FERM domain containing 5 | -0.0192484 |
| RPL18 | ribosomal protein L18 | -0.0192182 |
| S100A10 | S100 calcium binding protein A10 | -0.0192128 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0190193 |
| DIAPH2 | diaphanous-related formin 2 | -0.0189401 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0188901 |
| RRBP1 | ribosome binding protein 1 | -0.0188359 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0187509 |
| DGKH | diacylglycerol kinase, eta | -0.018588 |
| RIN2 | Ras and Rab interactor 2 | -0.0177138 |
| MT1X | metallothionein 1X | -0.0176645 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0173951 |
| CBX3 | chromobox homolog 3 | -0.0173631 |
| AHI1 | Abelson helper integration site 1 | -0.0173335 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0171419 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0171147 |
| JUN | jun proto-oncogene | -0.0169025 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0167188 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0165524 |
| GNAS | GNAS complex locus | -0.0165072 |
| LSAMP | limbic system-associated membrane protein | -0.0163171 |
| DEK | DEK proto-oncogene | -0.016293 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0161461 |
| ONECUT3 | one cut homeobox 3 | -0.0161395 |
| CSTB | cystatin B (stefin B) | -0.0161231 |
| AGR2 | anterior gradient 2 | -0.0161199 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0160483 |
| CNKSR3 | CNKSR family member 3 | -0.0155894 |
| RPS10 | ribosomal protein S10 | -0.0155137 |
| ZNF33A | zinc finger protein 33A | -0.015508 |
| GPR39 | G protein-coupled receptor 39 | -0.015356 |
| S100A9 | S100 calcium binding protein A9 | -0.015248 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0151921 |
| VCAN | versican | -0.0148346 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.014829 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0145898 |
| SERF2 | small EDRK-rich factor 2 | -0.01429 |
| PKP2 | plakophilin 2 | -0.0141444 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0140403 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0140108 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0139991 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0138341 |
