| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.130406 |
| DST | dystonin | 0.129595 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0953634 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0881407 |
| CANX | calnexin | 0.0729025 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0719414 |
| CD44 | CD44 molecule (Indian blood group) | 0.0709406 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0709378 |
| EHBP1 | EH domain binding protein 1 | 0.0667374 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0660836 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0654754 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0654646 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0649409 |
| RAI1 | retinoic acid induced 1 | 0.064673 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.064072 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0635453 |
| HLA-B | major histocompatibility complex, class I, B | 0.0597189 |
| YEATS2 | YEATS domain containing 2 | 0.0596839 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0586294 |
| EFNA5 | ephrin-A5 | 0.0572895 |
| LOXL2 | lysyl oxidase-like 2 | 0.0563066 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0558769 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0542004 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0524126 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0498693 |
| PGK1 | phosphoglycerate kinase 1 | 0.0491351 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.046445 |
| RAD51B | RAD51 paralog B | 0.0462718 |
| SLK | STE20-like kinase | 0.0455747 |
| EPHA4 | EPH receptor A4 | 0.0446622 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0443141 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0442965 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0440249 |
| TMEM123 | transmembrane protein 123 | 0.0438634 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0429159 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0428056 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0424464 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0420966 |
| FMNL2 | formin-like 2 | 0.0408751 |
| TPM4 | tropomyosin 4 | 0.040635 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0404552 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0398046 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0396172 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0393047 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.038795 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0382251 |
| RUNX1 | runt-related transcription factor 1 | 0.0377583 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0377542 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.037547 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0372517 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.036592 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0353396 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0351796 |
| ANXA2 | annexin A2 | 0.0351408 |
| CENPF | centromere protein F, 350/400kDa | 0.0351181 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.035067 |
| SQSTM1 | sequestosome 1 | 0.0348981 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0346965 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0346302 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0341781 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0337419 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333358 |
| RPL37A | ribosomal protein L37a | 0.0332527 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0321762 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321671 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0317704 |
| EZR | ezrin | 0.0313416 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0311076 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0310845 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0310136 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0310049 |
| TNS3 | tensin 3 | 0.0306011 |
| RPL12 | ribosomal protein L12 | 0.0303604 |
| RPS27 | ribosomal protein S27 | 0.0301894 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0301312 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0297171 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | 0.0291368 |
| SFTPA2 | surfactant protein A2 | 0.0289632 |
| PYGL | phosphorylase, glycogen, liver | 0.0288305 |
| RPS2 | ribosomal protein S2 | 0.0287513 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0285839 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0285024 |
| BPTF | bromodomain PHD finger transcription factor | 0.0284821 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0279477 |
| RPLP0 | ribosomal protein, large, P0 | 0.0277203 |
| TP63 | tumor protein p63 | 0.0276121 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0275481 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0275248 |
| GOLGB1 | golgin B1 | 0.0268011 |
| ADAR | adenosine deaminase, RNA-specific | 0.0267567 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0266886 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0265359 |
| RPL11 | ribosomal protein L11 | 0.0264938 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0264479 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.025923 |
| APP | amyloid beta (A4) precursor protein | 0.025867 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.025794 |
| LRRC49 | leucine rich repeat containing 49 | 0.0257442 |
| DENND1A | DENN/MADD domain containing 1A | 0.0256087 |
| ZNF217 | zinc finger protein 217 | 0.0255785 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.219827 |
| UBC | ubiquitin C | -0.173762 |
| MT2A | metallothionein 2A | -0.140431 |
| VIM | vimentin | -0.121281 |
| MT1X | metallothionein 1X | -0.116209 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.113606 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0957562 |
| JUN | jun proto-oncogene | -0.0954027 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0909711 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.087078 |
| RPS27A | ribosomal protein S27a | -0.0761322 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0724967 |
| POTEF | POTE ankyrin domain family, member F | -0.062698 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0597921 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0557759 |
| S100A6 | S100 calcium binding protein A6 | -0.0446365 |
| EMP1 | epithelial membrane protein 1 | -0.0393827 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0348624 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0328701 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0317543 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0317474 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0310781 |
| TXNRD1 | thioredoxin reductase 1 | -0.0306821 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0285815 |
| PCBP2 | poly(rC) binding protein 2 | -0.0283684 |
| RPL23 | ribosomal protein L23 | -0.027983 |
| EGR1 | early growth response 1 | -0.0277312 |
| MCL1 | myeloid cell leukemia 1 | -0.0255139 |
| S100A10 | S100 calcium binding protein A10 | -0.0248173 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0247473 |
| AHNAK | AHNAK nucleoprotein | -0.024421 |
| ENO1 | enolase 1, (alpha) | -0.0238043 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0237956 |
| RBM25 | RNA binding motif protein 25 | -0.0237047 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0236857 |
| YBX3 | Y box binding protein 3 | -0.0236414 |
| RHOA | ras homolog family member A | -0.0236264 |
| PFN1 | profilin 1 | -0.0235332 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0232732 |
| RPL18 | ribosomal protein L18 | -0.0228847 |
| ACTG1 | actin gamma 1 | -0.022458 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0223909 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0223222 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0207621 |
| RPLP2 | ribosomal protein, large, P2 | -0.0205762 |
| RPS3 | ribosomal protein S3 | -0.0194175 |
| RPS4X | ribosomal protein S4, X-linked | -0.0192618 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.019081 |
| SDC4 | syndecan 4 | -0.0189942 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0187805 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0185783 |
| RPL5 | ribosomal protein L5 | -0.0185444 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0184751 |
| VMP1 | vacuole membrane protein 1 | -0.0184652 |
| FTL | ferritin, light polypeptide | -0.018244 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0181612 |
| RTN4 | reticulon 4 | -0.0177498 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0177482 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0174319 |
| HMGB2 | high mobility group box 2 | -0.0174093 |
| MT1E | metallothionein 1E | -0.0172992 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0172366 |
| RPL32 | ribosomal protein L32 | -0.0172315 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0170835 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0170146 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0169575 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | -0.0166693 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0163388 |
| RPL15 | ribosomal protein L15 | -0.016118 |
| HMGB1 | high mobility group box 1 | -0.0159701 |
| RAB7A | RAB7A, member RAS oncogene family | -0.015907 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0158318 |
| RPS15 | ribosomal protein S15 | -0.0158154 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0156513 |
| UPP1 | uridine phosphorylase 1 | -0.0156308 |
| RPL28 | ribosomal protein L28 | -0.0155563 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0155356 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.015218 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | -0.0151653 |
| CERS2 | ceramide synthase 2 | -0.0151511 |
| RPL8 | ribosomal protein L8 | -0.0150311 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0149 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0146998 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0146786 |
| RPS24 | ribosomal protein S24 | -0.0142483 |
| KHSRP | KH-type splicing regulatory protein | -0.0142154 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0140622 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0139274 |
| BRD2 | bromodomain containing 2 | -0.0137091 |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) | -0.013615 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0133449 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.013265 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0132542 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0132173 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0131396 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | -0.0130816 |
| SON | SON DNA binding protein | -0.0130255 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0126976 |
| SET | SET nuclear proto-oncogene | -0.0125993 |
| RECQL | RecQ helicase-like | -0.0125702 |
