| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.122163 |
| CES1 | carboxylesterase 1 | 0.0825449 |
| FAM13A | family with sequence similarity 13, member A | 0.0771823 |
| SPAG9 | sperm associated antigen 9 | 0.0598146 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0566359 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0554605 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0542076 |
| OGA | O-GlcNAcase | 0.0523325 |
| NGLY1 | N-glycanase 1 | 0.0491095 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.048857 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0478443 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0468337 |
| RUNX1 | runt-related transcription factor 1 | 0.0468277 |
| ARRDC3 | arrestin domain containing 3 | 0.0460427 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0447923 |
| TOP1 | topoisomerase (DNA) I | 0.0441635 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0430287 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0423139 |
| HELZ | helicase with zinc finger | 0.0417115 |
| MKI67 | marker of proliferation Ki-67 | 0.0414926 |
| JMJD1C | jumonji domain containing 1C | 0.0400505 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0392441 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0387974 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0382135 |
| USP34 | ubiquitin specific peptidase 34 | 0.0375091 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0368091 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0367184 |
| NPTN | neuroplastin | 0.0364779 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0362217 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.03589 |
| TMEM165 | transmembrane protein 165 | 0.0353724 |
| ATXN7 | ataxin 7 | 0.0348229 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0348112 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0332823 |
| FNIP1 | folliculin interacting protein 1 | 0.0330224 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0325052 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0322124 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0320465 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0319831 |
| YEATS2 | YEATS domain containing 2 | 0.0319333 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0318541 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0315259 |
| ZNF638 | zinc finger protein 638 | 0.0313919 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0312943 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0308027 |
| PCBP2 | poly(rC) binding protein 2 | 0.0305477 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0304816 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0297772 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0289178 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0284843 |
| UVRAG | UV radiation resistance associated | 0.0283333 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0280518 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0279214 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.027882 |
| CANX | calnexin | 0.0277331 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0276764 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0275953 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0274945 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.027273 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0271943 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.027155 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0270334 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0263686 |
| METTL15 | methyltransferase like 15 | 0.0261246 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0260949 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0259733 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0258898 |
| ANO6 | anoctamin 6 | 0.0257752 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0255814 |
| YAP1 | Yes-associated protein 1 | 0.025527 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0254049 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0252712 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0252707 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0251842 |
| HYOU1 | hypoxia up-regulated 1 | 0.0248747 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0248289 |
| WDR45B | WD repeat domain 45B | 0.024723 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0244637 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0243843 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0243434 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.024058 |
| SUCO | SUN domain containing ossification factor | 0.023996 |
| SLTM | SAFB-like, transcription modulator | 0.0238461 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0237984 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0237371 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0237244 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0237163 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0234272 |
| YTHDC1 | YTH domain containing 1 | 0.0231973 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0230603 |
| NCKAP1 | NCK-associated protein 1 | 0.0230594 |
| HDLBP | high density lipoprotein binding protein | 0.022961 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0228752 |
| TFG | TRK-fused gene | 0.0227218 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0225497 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0225163 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0223503 |
| MED13L | mediator complex subunit 13-like | 0.0223236 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0219298 |
| CUL4A | cullin 4A | 0.0218093 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.154425 |
| ASPH | aspartate beta-hydroxylase | -0.102617 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0973742 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0927637 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0820609 |
| ACTG1 | actin gamma 1 | -0.0793728 |
| S100A10 | S100 calcium binding protein A10 | -0.0728882 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0722192 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.071218 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0677931 |
| LAMC2 | laminin, gamma 2 | -0.0634292 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0598009 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0585939 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.058079 |
| EFNA5 | ephrin-A5 | -0.0543835 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0529341 |
| CST3 | cystatin C | -0.052817 |
| EGR1 | early growth response 1 | -0.0510531 |
| CCND1 | cyclin D1 | -0.0495209 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0462361 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0455678 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0454342 |
| RNF213 | ring finger protein 213 | -0.0443274 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.043702 |
| KRT18 | keratin 18, type I | -0.0429543 |
| OSMR | oncostatin M receptor | -0.0427736 |
| KRT7 | keratin 7, type II | -0.0380325 |
| FOXP1 | forkhead box P1 | -0.0378797 |
| FTL | ferritin, light polypeptide | -0.0376016 |
| AREG | amphiregulin | -0.0373941 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0372042 |
| GRAMD1B | GRAM domain containing 1B | -0.0368345 |
| RPL35A | ribosomal protein L35a | -0.036561 |
| TPM4 | tropomyosin 4 | -0.0355029 |
| MYOF | myoferlin | -0.0352155 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0350754 |
| LOC112694756 | uncharaterized LOC112694756 | -0.034484 |
| HLA-B | major histocompatibility complex, class I, B | -0.0342877 |
| SCEL | sciellin | -0.0339681 |
| B2M | beta-2-microglobulin | -0.0338851 |
| CUX1 | cut-like homeobox 1 | -0.0324049 |
| AHNAK | AHNAK nucleoprotein | -0.0317407 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0315826 |
| PKM | pyruvate kinase, muscle | -0.0314711 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0313862 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0313496 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0305872 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0305252 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0301718 |
| LMO7 | LIM domain 7 | -0.0301358 |
| VCL | vinculin | -0.0298757 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0298047 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0296991 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0296821 |
| MYO1E | myosin IE | -0.0295889 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0293517 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0291732 |
| S100A11 | S100 calcium binding protein A11 | -0.0290793 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0289704 |
| TRIM56 | tripartite motif containing 56 | -0.028963 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.028922 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0284616 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0284262 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0283255 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0275519 |
| RPS24 | ribosomal protein S24 | -0.0274495 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0270464 |
| TNS3 | tensin 3 | -0.0269974 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0268351 |
| IER3 | immediate early response 3 | -0.0265422 |
| LAMA4 | laminin, alpha 4 | -0.0263185 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0261435 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0256704 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0255462 |
| SP100 | SP100 nuclear antigen | -0.0253062 |
| SMYD3 | SET and MYND domain containing 3 | -0.02425 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239678 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0237609 |
| MYO1D | myosin ID | -0.0236718 |
| RAB10 | RAB10, member RAS oncogene family | -0.0235459 |
| INTS6 | integrator complex subunit 6 | -0.0234632 |
| NTN4 | netrin 4 | -0.0232497 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.022894 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0225791 |
| ENO1 | enolase 1, (alpha) | -0.0225585 |
| LDHA | lactate dehydrogenase A | -0.0225273 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0223585 |
| RPL34 | ribosomal protein L34 | -0.0223 |
| MT2A | metallothionein 2A | -0.0221025 |
| S100A6 | S100 calcium binding protein A6 | -0.0220773 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0220561 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0219783 |
| RPS25 | ribosomal protein S25 | -0.0217678 |
| RAD51B | RAD51 paralog B | -0.0213506 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0211418 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0207319 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0207128 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0206841 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0204154 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0202636 |
