| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.101083 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.093777 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0668491 |
| RBM39 | RNA binding motif protein 39 | 0.0655368 |
| GOLGA4 | golgin A4 | 0.0601878 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0574562 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0566161 |
| NAV2 | neuron navigator 2 | 0.047559 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0474544 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0448837 |
| FAM13A | family with sequence similarity 13, member A | 0.0437857 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0431004 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0430825 |
| SETD5 | SET domain containing 5 | 0.0426334 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0414846 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0409655 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0403869 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0399544 |
| NGLY1 | N-glycanase 1 | 0.0399309 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0387873 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0378608 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0375323 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0367429 |
| YEATS2 | YEATS domain containing 2 | 0.0365014 |
| CD109 | CD109 molecule | 0.03521 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0350968 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0350526 |
| PRELID2 | PRELI domain containing 2 | 0.0335417 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0333867 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0331325 |
| OSMR | oncostatin M receptor | 0.032753 |
| RAD51B | RAD51 paralog B | 0.032564 |
| SRP54 | signal recognition particle 54kDa | 0.0310142 |
| ADD3 | adducin 3 (gamma) | 0.0301385 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0295719 |
| ARF4 | ADP-ribosylation factor 4 | 0.0295235 |
| ZNF292 | zinc finger protein 292 | 0.0294537 |
| AOPEP | aminopeptidase O (putative) | 0.029427 |
| ANXA2 | annexin A2 | 0.0287925 |
| USP34 | ubiquitin specific peptidase 34 | 0.0283082 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0278263 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0276609 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0275895 |
| RUNX2 | runt-related transcription factor 2 | 0.0275802 |
| OGA | O-GlcNAcase | 0.0275263 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0274451 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0268801 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0267049 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0265848 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0265604 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0265291 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0258004 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0256523 |
| SBF2 | SET binding factor 2 | 0.0254413 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0253636 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0252735 |
| COPA | coatomer protein complex, subunit alpha | 0.0250422 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0249239 |
| LRRC49 | leucine rich repeat containing 49 | 0.0243411 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0240678 |
| RAB27A | RAB27A, member RAS oncogene family | 0.0236091 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0236055 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0235923 |
| HDAC9 | histone deacetylase 9 | 0.023492 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0234122 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0230999 |
| VEGFA | vascular endothelial growth factor A | 0.0228389 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0226919 |
| FN1 | fibronectin 1 | 0.0225096 |
| SCFD1 | sec1 family domain containing 1 | 0.0224501 |
| CCDC88A | coiled-coil domain containing 88A | 0.0222859 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0221776 |
| SUCO | SUN domain containing ossification factor | 0.0217994 |
| SEC24A | SEC24 family member A | 0.021659 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0211968 |
| CANX | calnexin | 0.0211592 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0210279 |
| CEP250 | centrosomal protein 250kDa | 0.0209072 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0208876 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.020831 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0207183 |
| MYO1E | myosin IE | 0.0207051 |
| RASA2 | RAS p21 protein activator 2 | 0.0204015 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0202856 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0202578 |
| PYGL | phosphorylase, glycogen, liver | 0.0202404 |
| ATXN1 | ataxin 1 | 0.0200264 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0198942 |
| GOLGA3 | golgin A3 | 0.0197589 |
| FAM20C | family with sequence similarity 20, member C | 0.0195508 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0194846 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0193717 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0191712 |
| SNX13 | sorting nexin 13 | 0.01881 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0187972 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0187889 |
| JMJD1C | jumonji domain containing 1C | 0.0187531 |
| PDGFC | platelet derived growth factor C | 0.0187272 |
| PFKP | phosphofructokinase, platelet | 0.0186016 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0184835 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.224114 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.220532 |
| TMSB10 | thymosin beta 10 | -0.170991 |
| UBC | ubiquitin C | -0.148617 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.145412 |
| CD44 | CD44 molecule (Indian blood group) | -0.117522 |
| MT2A | metallothionein 2A | -0.108323 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101085 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0986555 |
| PCBP2 | poly(rC) binding protein 2 | -0.0930153 |
| FTL | ferritin, light polypeptide | -0.0863533 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0822618 |
| AHNAK | AHNAK nucleoprotein | -0.0821184 |
| ENO1 | enolase 1, (alpha) | -0.0706603 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0674053 |
| NRG1 | neuregulin 1 | -0.0649868 |
| RPS19 | ribosomal protein S19 | -0.0596249 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0593415 |
| RPL23 | ribosomal protein L23 | -0.0590333 |
| PTMA | prothymosin, alpha | -0.0590312 |
| IER3 | immediate early response 3 | -0.0578207 |
| RPLP1 | ribosomal protein, large, P1 | -0.0557156 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.050546 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0495063 |
| MTSS1 | metastasis suppressor 1 | -0.0492881 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0489609 |
| LOX | lysyl oxidase | -0.0478556 |
| CALR | calreticulin | -0.045631 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0449064 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0447392 |
| RPS27A | ribosomal protein S27a | -0.0446523 |
| TMSB4X | thymosin beta 4, X-linked | -0.0445514 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.04437 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0434306 |
| PKM | pyruvate kinase, muscle | -0.0421187 |
| RPL32 | ribosomal protein L32 | -0.0414769 |
| RPL4 | ribosomal protein L4 | -0.0413995 |
| CDH13 | cadherin 13 | -0.0413297 |
| RPLP2 | ribosomal protein, large, P2 | -0.0406083 |
| RPS12 | ribosomal protein S12 | -0.0403634 |
| JUN | jun proto-oncogene | -0.0392383 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0390924 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0384742 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0370743 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0367517 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0367175 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0359901 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0352541 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0347751 |
| LDHA | lactate dehydrogenase A | -0.0347336 |
| ANGPTL4 | angiopoietin-like 4 | -0.0346288 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0343849 |
| STC1 | stanniocalcin 1 | -0.0339691 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0334254 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0329034 |
| RPS3 | ribosomal protein S3 | -0.0325298 |
| RPL12 | ribosomal protein L12 | -0.0324623 |
| B2M | beta-2-microglobulin | -0.0324615 |
| NUMB | numb homolog (Drosophila) | -0.0315401 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0312826 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0303209 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0303007 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0301871 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0299929 |
| SP100 | SP100 nuclear antigen | -0.0299582 |
| ASPH | aspartate beta-hydroxylase | -0.0295045 |
| RPL28 | ribosomal protein L28 | -0.0291275 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0287361 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0287012 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0286175 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0285181 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0284458 |
| RPS8 | ribosomal protein S8 | -0.0283117 |
| S100A10 | S100 calcium binding protein A10 | -0.0282695 |
| APP | amyloid beta (A4) precursor protein | -0.0282434 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0282106 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0279379 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0279293 |
| RPS24 | ribosomal protein S24 | -0.0272296 |
| RPL31 | ribosomal protein L31 | -0.0265285 |
| POTEF | POTE ankyrin domain family, member F | -0.0263435 |
| ACTG1 | actin gamma 1 | -0.0262246 |
| RPL5 | ribosomal protein L5 | -0.026135 |
| TXNRD1 | thioredoxin reductase 1 | -0.0259464 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0259285 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0257597 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0257258 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0254652 |
| S100A6 | S100 calcium binding protein A6 | -0.0247654 |
| RPL18 | ribosomal protein L18 | -0.0243625 |
| RPL19 | ribosomal protein L19 | -0.0242794 |
| IL1B | interleukin 1, beta | -0.0242464 |
| AADAC | arylacetamide deacetylase | -0.0239368 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0236483 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0234903 |
| RPL34 | ribosomal protein L34 | -0.0233497 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0232897 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0232577 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0232403 |
| HPCAL1 | hippocalcin-like 1 | -0.0226988 |
