| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | 0.174456 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.15653 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.143923 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.117895 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.107251 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.105678 |
| FAM13A | family with sequence similarity 13, member A | 0.104268 |
| TXNRD1 | thioredoxin reductase 1 | 0.104022 |
| EFNA5 | ephrin-A5 | 0.100216 |
| DSCAM | Down syndrome cell adhesion molecule | 0.100177 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.100138 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0978268 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0974404 |
| ATP11A | ATPase, class VI, type 11A | 0.0970957 |
| PGK1 | phosphoglycerate kinase 1 | 0.0948018 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0904003 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0896363 |
| KYNU | kynureninase | 0.0844223 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0836195 |
| PDE10A | phosphodiesterase 10A | 0.0809163 |
| FN1 | fibronectin 1 | 0.0807213 |
| PTK2 | protein tyrosine kinase 2 | 0.0763919 |
| MYOF | myoferlin | 0.0740965 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0736735 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0735846 |
| OGA | O-GlcNAcase | 0.0679462 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0668862 |
| RPL26 | ribosomal protein L26 | 0.066802 |
| RPL37A | ribosomal protein L37a | 0.0652977 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0626693 |
| BBX | bobby sox homolog (Drosophila) | 0.0625111 |
| PTMA | prothymosin, alpha | 0.061096 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0608348 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0602902 |
| NF1 | neurofibromin 1 | 0.0581147 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0570337 |
| LMO7 | LIM domain 7 | 0.0566174 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0562601 |
| MED13L | mediator complex subunit 13-like | 0.056204 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0558591 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0556623 |
| MICU1 | mitochondrial calcium uptake 1 | 0.0547301 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0544092 |
| RPS8 | ribosomal protein S8 | 0.054125 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0538868 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0536181 |
| RPS6 | ribosomal protein S6 | 0.0526182 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0509381 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0507292 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0503499 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0497978 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0497294 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0491295 |
| RPS3 | ribosomal protein S3 | 0.0482689 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0481999 |
| VIM | vimentin | 0.0480209 |
| DNER | delta/notch-like EGF repeat containing | 0.047068 |
| TJP1 | tight junction protein 1 | 0.045741 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0457113 |
| FOXJ3 | forkhead box J3 | 0.0453803 |
| B2M | beta-2-microglobulin | 0.0450005 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0446451 |
| RPL7 | ribosomal protein L7 | 0.0427064 |
| SRP54 | signal recognition particle 54kDa | 0.042246 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0410154 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.040374 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0403673 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0401965 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0399398 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0396426 |
| RBM39 | RNA binding motif protein 39 | 0.0395443 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0391279 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0380501 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0378812 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0372956 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0372641 |
| FNDC3A | fibronectin type III domain containing 3A | 0.037217 |
| RPS25 | ribosomal protein S25 | 0.0371325 |
| SQSTM1 | sequestosome 1 | 0.0370741 |
| THOC2 | THO complex 2 | 0.0369573 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0368203 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.036315 |
| MATR3 | matrin 3 | 0.0359771 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0358782 |
| MED13 | mediator complex subunit 13 | 0.0358712 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.034939 |
| SETD5 | SET domain containing 5 | 0.034453 |
| CLINT1 | clathrin interactor 1 | 0.0342005 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0334465 |
| CTBP2 | C-terminal binding protein 2 | 0.0334169 |
| NUP58 | nucleoporin 58 | 0.0333948 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | 0.0332909 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0331723 |
| RPLP0 | ribosomal protein, large, P0 | 0.0329878 |
| FMNL2 | formin-like 2 | 0.032944 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0329234 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0327805 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.032438 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0323589 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0322185 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.092026 |
| IGF2 | insulin-like growth factor 2 | -0.090358 |
| KRT17 | keratin 17, type I | -0.0883316 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0881017 |
| LAMB3 | laminin, beta 3 | -0.0852483 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0815328 |
| NDRG1 | N-myc downstream regulated 1 | -0.077425 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0716454 |
| RUNX1 | runt-related transcription factor 1 | -0.0678269 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0658056 |
| DSPP | dentin sialophosphoprotein | -0.0632243 |
| S100A9 | S100 calcium binding protein A9 | -0.0611213 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0606064 |
| FMN1 | formin 1 | -0.0582768 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0569713 |
| SDC4 | syndecan 4 | -0.0558194 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0554244 |
| NPTN | neuroplastin | -0.0539113 |
| VCL | vinculin | -0.0534999 |
| PTGES2 | prostaglandin E synthase 2 | -0.0530021 |
| EZR | ezrin | -0.0526148 |
| MCL1 | myeloid cell leukemia 1 | -0.0519912 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0519552 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0518037 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0500004 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0490766 |
| OSMR | oncostatin M receptor | -0.0490189 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0482812 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0478952 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.047262 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.047082 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0468604 |
| CD44 | CD44 molecule (Indian blood group) | -0.046387 |
| GLG1 | golgi glycoprotein 1 | -0.0463799 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0463058 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0461808 |
| RPS20 | ribosomal protein S20 | -0.0457654 |
| KIF13B | kinesin family member 13B | -0.0457145 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0448016 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0442061 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0440276 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0435561 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0434883 |
| FLNB | filamin B, beta | -0.0433271 |
| RAD51B | RAD51 paralog B | -0.0432873 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0431423 |
| EXOC6B | exocyst complex component 6B | -0.0431256 |
| RPL34 | ribosomal protein L34 | -0.0430895 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.0429455 |
| MAP4 | microtubule-associated protein 4 | -0.042715 |
| TXNIP | thioredoxin interacting protein | -0.0426287 |
| TMEM87A | transmembrane protein 87A | -0.042504 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0421434 |
| ATOSA | atos homolog A | -0.0421409 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0419645 |
| TPM4 | tropomyosin 4 | -0.0418399 |
| RACK1 | receptor for activated C kinase 1 | -0.0418081 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0414825 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0411162 |
| PARD3 | par-3 family cell polarity regulator | -0.0410603 |
| RPL18 | ribosomal protein L18 | -0.0408734 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0408374 |
| ACTG1 | actin gamma 1 | -0.0406412 |
| ABI1 | abl-interactor 1 | -0.0404934 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0403673 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0400099 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0397802 |
| CDCP1 | CUB domain containing protein 1 | -0.0396792 |
| SVIL | supervillin | -0.039438 |
| S100A11 | S100 calcium binding protein A11 | -0.039347 |
| IER3 | immediate early response 3 | -0.0393385 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0391473 |
| FAM193A | family with sequence similarity 193, member A | -0.0390819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.038903 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0388286 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0387421 |
| MBTD1 | mbt domain containing 1 | -0.038433 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0382399 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0378376 |
| DSG2 | desmoglein 2 | -0.037684 |
| SLC38A1 | solute carrier family 38, member 1 | -0.037264 |
| G0S2 | G0/G1 switch 2 | -0.0372537 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0370981 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0370969 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0370908 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0369848 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.0366897 |
| EHBP1 | EH domain binding protein 1 | -0.0358886 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0358819 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0358331 |
| DENND4A | DENN/MADD domain containing 4A | -0.0357727 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0355657 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0354652 |
| RBM25 | RNA binding motif protein 25 | -0.035464 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0352404 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0350039 |
| HMGA2 | high mobility group AT-hook 2 | -0.0349342 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0346517 |
| JMJD1C | jumonji domain containing 1C | -0.0344566 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0343968 |
