| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.229751 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.150603 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.125633 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.111144 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.110284 |
| NAV2 | neuron navigator 2 | 0.085678 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.082848 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0790815 |
| EFNA5 | ephrin-A5 | 0.0790066 |
| PLEC | plectin | 0.0784527 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0767648 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0733437 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0733358 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0732854 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0728999 |
| SQSTM1 | sequestosome 1 | 0.0707426 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0682593 |
| AHNAK | AHNAK nucleoprotein | 0.0677686 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0668315 |
| NDRG1 | N-myc downstream regulated 1 | 0.0660926 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0635746 |
| DSPP | dentin sialophosphoprotein | 0.0632928 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0627837 |
| CANX | calnexin | 0.061469 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.05682 |
| PTK2 | protein tyrosine kinase 2 | 0.0551942 |
| VCL | vinculin | 0.0505733 |
| CTSB | cathepsin B | 0.0505326 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.049764 |
| ENO1 | enolase 1, (alpha) | 0.0492499 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0491682 |
| LAMC2 | laminin, gamma 2 | 0.0489065 |
| RNF213 | ring finger protein 213 | 0.0478779 |
| SMAD3 | SMAD family member 3 | 0.0470168 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0461972 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0458154 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0452687 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0442722 |
| FHIT | fragile histidine triad | 0.043715 |
| ANXA2 | annexin A2 | 0.0431034 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0410821 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0405645 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0402137 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0399244 |
| CALR | calreticulin | 0.0388299 |
| RAD51B | RAD51 paralog B | 0.0387472 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0382604 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0368253 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0367258 |
| FLNB | filamin B, beta | 0.0364297 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0356643 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0354736 |
| PALLD | palladin, cytoskeletal associated protein | 0.0348404 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0341473 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0339767 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0338899 |
| FBXO32 | F-box protein 32 | 0.033465 |
| TPM4 | tropomyosin 4 | 0.03321 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0329317 |
| MYO1E | myosin IE | 0.0327832 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0323817 |
| MX1 | MX dynamin-like GTPase 1 | 0.0321363 |
| ATXN1 | ataxin 1 | 0.032048 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0320328 |
| RIGI | RNA sensor RIG-I | 0.0320284 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0317984 |
| OSMR | oncostatin M receptor | 0.0303435 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0301214 |
| TUFT1 | tuftelin 1 | 0.0300231 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0299281 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0298603 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0297595 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0292118 |
| PRKCA | protein kinase C, alpha | 0.0291447 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0290966 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0290505 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0288079 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0284538 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0284054 |
| SEPTIN9 | septin 9 | 0.0283217 |
| GOLGB1 | golgin B1 | 0.0282933 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0282314 |
| STEAP4 | STEAP family member 4 | 0.0280944 |
| KIAA1217 | KIAA1217 | 0.0279663 |
| MX2 | MX dynamin-like GTPase 2 | 0.0277875 |
| ADAR | adenosine deaminase, RNA-specific | 0.0277749 |
| ASPH | aspartate beta-hydroxylase | 0.0277483 |
| RCOR1 | REST corepressor 1 | 0.0275715 |
| FBXO34 | F-box protein 34 | 0.0275214 |
| CD47 | CD47 molecule | 0.0274096 |
| FNIP1 | folliculin interacting protein 1 | 0.026965 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.02696 |
| MCL1 | myeloid cell leukemia 1 | 0.0263272 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0260034 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.025726 |
| ARRDC3 | arrestin domain containing 3 | 0.0257233 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0257137 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0257095 |
| LAMB3 | laminin, beta 3 | 0.0255339 |
| OGA | O-GlcNAcase | 0.0252341 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.123346 |
| FTL | ferritin, light polypeptide | -0.0716268 |
| POTEF | POTE ankyrin domain family, member F | -0.0712387 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0653191 |
| RNF145 | ring finger protein 145 | -0.0635925 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0580974 |
| RBM25 | RNA binding motif protein 25 | -0.0535463 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.049213 |
| PTMA | prothymosin, alpha | -0.0483008 |
| GOLGA4 | golgin A4 | -0.0460548 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0439079 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0424015 |
| HMGA1 | high mobility group AT-hook 1 | -0.04084 |
| CCNL1 | cyclin L1 | -0.0403096 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0374396 |
| COPA | coatomer protein complex, subunit alpha | -0.0335563 |
| RPS19 | ribosomal protein S19 | -0.0316837 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0306862 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0297957 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0296608 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0287278 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0286905 |
| RPL35A | ribosomal protein L35a | -0.0282409 |
| TSC22D2 | TSC22 domain family, member 2 | -0.027664 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0271129 |
| FAM3C | family with sequence similarity 3, member C | -0.0258145 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0255243 |
| JMJD1C | jumonji domain containing 1C | -0.0254305 |
| RPL32 | ribosomal protein L32 | -0.0253815 |
| QKI | QKI, KH domain containing, RNA binding | -0.0242351 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0228008 |
| MT2A | metallothionein 2A | -0.0223326 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0222403 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0219229 |
| USP3 | ubiquitin specific peptidase 3 | -0.0217114 |
| TMSB4X | thymosin beta 4, X-linked | -0.0216582 |
| S100A6 | S100 calcium binding protein A6 | -0.0215733 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0215193 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0214594 |
| TMEM263 | transmembrane protein 263 | -0.021421 |
| VIM | vimentin | -0.0211727 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0208326 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.0206277 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0206001 |
| AREG | amphiregulin | -0.0202598 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0198186 |
| RPL36 | ribosomal protein L36 | -0.0193547 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0192366 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0192002 |
| RLF | rearranged L-myc fusion | -0.0191678 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0191633 |
| TFG | TRK-fused gene | -0.0190243 |
| PFN1 | profilin 1 | -0.0188519 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0186278 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0174474 |
| MATR3 | matrin 3 | -0.0172537 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0170116 |
| CDK17 | cyclin-dependent kinase 17 | -0.0169832 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0169792 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0169364 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0168317 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.016811 |
| AZIN1 | antizyme inhibitor 1 | -0.0166748 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.016581 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0162719 |
| CSTB | cystatin B (stefin B) | -0.0159492 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0158447 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0158185 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0157242 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0156534 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0155016 |
| SEC24D | SEC24 family member D | -0.0148819 |
| RPS14 | ribosomal protein S14 | -0.0148176 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0148149 |
| TOP1 | topoisomerase (DNA) I | -0.0147486 |
| SETD5 | SET domain containing 5 | -0.01471 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0146733 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.014581 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0145044 |
| DSTN | destrin (actin depolymerizing factor) | -0.0143703 |
| NOP58 | NOP58 ribonucleoprotein | -0.0143247 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0142882 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0142419 |
| CBX3 | chromobox homolog 3 | -0.0142183 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | -0.0141737 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0141009 |
| RPS6 | ribosomal protein S6 | -0.0140759 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0140637 |
| RBM27 | RNA binding motif protein 27 | -0.0139575 |
| RPL18 | ribosomal protein L18 | -0.0139511 |
| FBXO11 | F-box protein 11 | -0.0139206 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0138731 |
| RPL23 | ribosomal protein L23 | -0.0137158 |
| RBM39 | RNA binding motif protein 39 | -0.0136712 |
| ASTN2 | astrotactin 2 | -0.0135613 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0135242 |
| CENPE | centromere protein E, 312kDa | -0.0133934 |
| RPL5 | ribosomal protein L5 | -0.013338 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0131582 |
| RPS3 | ribosomal protein S3 | -0.0130791 |
