| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.159496 |
| EFNA5 | ephrin-A5 | 0.148148 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.111363 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.11087 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.109288 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.101822 |
| GRAMD1B | GRAM domain containing 1B | 0.0917659 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0866185 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0855739 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0831191 |
| NEK7 | NIMA-related kinase 7 | 0.0790164 |
| TXNRD1 | thioredoxin reductase 1 | 0.0784757 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0780912 |
| RTN4 | reticulon 4 | 0.0743166 |
| MCL1 | myeloid cell leukemia 1 | 0.0714044 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0695813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0671126 |
| FLNB | filamin B, beta | 0.0668137 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0660017 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0656261 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0652514 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0633179 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0630761 |
| PCBP2 | poly(rC) binding protein 2 | 0.0622815 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0607098 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0596328 |
| OGA | O-GlcNAcase | 0.0552545 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.054481 |
| ANXA2 | annexin A2 | 0.0539169 |
| EZR | ezrin | 0.0529012 |
| COL5A2 | collagen, type V, alpha 2 | 0.0525012 |
| CANX | calnexin | 0.0523082 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0522985 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0516624 |
| CENPF | centromere protein F, 350/400kDa | 0.0515897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0510985 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0496503 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.049638 |
| FN1 | fibronectin 1 | 0.0480104 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0476725 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0466911 |
| PDE10A | phosphodiesterase 10A | 0.0466493 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0462982 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0462704 |
| DST | dystonin | 0.0458852 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.045196 |
| RBM39 | RNA binding motif protein 39 | 0.0450584 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0441166 |
| NRCAM | neuronal cell adhesion molecule | 0.0431157 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.042527 |
| PGK1 | phosphoglycerate kinase 1 | 0.041671 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0411802 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0411238 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0407818 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0403731 |
| SPAG9 | sperm associated antigen 9 | 0.0400189 |
| MFF | mitochondrial fission factor | 0.0400057 |
| LDHA | lactate dehydrogenase A | 0.0393339 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0385844 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0385216 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0379381 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0377352 |
| MKI67 | marker of proliferation Ki-67 | 0.0377159 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.037638 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0374695 |
| NBAS | neuroblastoma amplified sequence | 0.0374265 |
| HELZ | helicase with zinc finger | 0.0373994 |
| ANXA1 | annexin A1 | 0.0371686 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0369945 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0365052 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0363102 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0362043 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0360795 |
| SFPQ | splicing factor proline/glutamine-rich | 0.035778 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0355858 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0352319 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0351501 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0351041 |
| PTEN | phosphatase and tensin homolog | 0.0350417 |
| USP34 | ubiquitin specific peptidase 34 | 0.0350376 |
| CUL4A | cullin 4A | 0.034821 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0346037 |
| TPM3 | tropomyosin 3 | 0.0342603 |
| GDA | guanine deaminase | 0.0342466 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0330116 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0328854 |
| NUP58 | nucleoporin 58 | 0.0328536 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0328517 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0325434 |
| PTMA | prothymosin, alpha | 0.0324347 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0321836 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0310781 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0309162 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0307568 |
| SUCO | SUN domain containing ossification factor | 0.0306802 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0305178 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0301427 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0301087 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0299882 |
| XPO1 | exportin 1 | 0.029919 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.198378 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.124763 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.106734 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.088872 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0775135 |
| TMSB10 | thymosin beta 10 | -0.0484616 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0456524 |
| AUTS2 | autism susceptibility candidate 2 | -0.0409734 |
| RPS24 | ribosomal protein S24 | -0.0389826 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0389117 |
| CDH13 | cadherin 13 | -0.0374976 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0363525 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0336243 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0322555 |
| SMAD2 | SMAD family member 2 | -0.0307609 |
| NCKAP5 | NCK-associated protein 5 | -0.0303447 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.028732 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0284221 |
| RPS6 | ribosomal protein S6 | -0.0282827 |
| RPS19 | ribosomal protein S19 | -0.0264211 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0263289 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0256924 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0245022 |
| SMYD3 | SET and MYND domain containing 3 | -0.0239812 |
| CADM2 | cell adhesion molecule 2 | -0.0230451 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0228085 |
| VCL | vinculin | -0.0225868 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0218313 |
| LSAMP | limbic system-associated membrane protein | -0.0216369 |
| SLC16A6 | solute carrier family 16, member 6 | -0.021608 |
| CUX1 | cut-like homeobox 1 | -0.0212514 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0211672 |
| XYLT1 | xylosyltransferase I | -0.0208066 |
| DENND1A | DENN/MADD domain containing 1A | -0.0207826 |
| PCDH9 | protocadherin 9 | -0.0207192 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0205462 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0201613 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0198445 |
| RPL35A | ribosomal protein L35a | -0.0192637 |
| SVIL | supervillin | -0.0192313 |
| INHBA | inhibin, beta A | -0.0191865 |
| NTN4 | netrin 4 | -0.0191711 |
| FMNL2 | formin-like 2 | -0.0190448 |
| AEBP2 | AE binding protein 2 | -0.0190343 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0185619 |
| RPL7A | ribosomal protein L7a | -0.0185464 |
| RANBP17 | RAN binding protein 17 | -0.0182922 |
| TENM3 | teneurin transmembrane protein 3 | -0.0181258 |
| RPL31 | ribosomal protein L31 | -0.0180069 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0177418 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0176619 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0175652 |
| TMSB4X | thymosin beta 4, X-linked | -0.0173768 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0172376 |
| IER3 | immediate early response 3 | -0.0172259 |
| STEAP1B | STEAP family member 1B | -0.016772 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0166526 |
| OXSR1 | oxidative stress responsive 1 | -0.0166487 |
| S100A6 | S100 calcium binding protein A6 | -0.0162412 |
| PDE7B | phosphodiesterase 7B | -0.0161971 |
| HLA-B | major histocompatibility complex, class I, B | -0.0161725 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0160526 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0158918 |
| FTL | ferritin, light polypeptide | -0.0158853 |
| KIAA0825 | KIAA0825 | -0.015799 |
| RPS4X | ribosomal protein S4, X-linked | -0.0156056 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0154607 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0153682 |
| ASTN2 | astrotactin 2 | -0.0153568 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0152497 |
| RAB31 | RAB31, member RAS oncogene family | -0.0148686 |
| RPS8 | ribosomal protein S8 | -0.0146254 |
| RPLP1 | ribosomal protein, large, P1 | -0.0146233 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0145936 |
| NLGN4Y | neuroligin 4, Y-linked | -0.0144752 |
| ACTG1 | actin gamma 1 | -0.0142458 |
| RPL34 | ribosomal protein L34 | -0.0141868 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0139329 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0138649 |
| INTS6 | integrator complex subunit 6 | -0.0138622 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 | -0.0138218 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.013742 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0137266 |
| PAPPA2 | pappalysin 2 | -0.0135013 |
| R3HDM2 | R3H domain containing 2 | -0.0134424 |
| RPS28 | ribosomal protein S28 | -0.0133973 |
| TMEM178B | transmembrane protein 178B | -0.0132772 |
| AADAC | arylacetamide deacetylase | -0.0131462 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0129575 |
| RPL36 | ribosomal protein L36 | -0.0129551 |
| FSTL4 | follistatin-like 4 | -0.0128824 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0128653 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0127291 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0127023 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0125704 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0124809 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0123887 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0123566 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0120028 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0119801 |
