| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.201937 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.151211 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.129374 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.122666 |
| FNDC3B | fibronectin type III domain containing 3B | 0.118879 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.116339 |
| AHNAK | AHNAK nucleoprotein | 0.108326 |
| ACTN4 | actinin, alpha 4 | 0.0969521 |
| SEPTIN9 | septin 9 | 0.0931544 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0897918 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0750334 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0744386 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0726323 |
| ASPH | aspartate beta-hydroxylase | 0.0722566 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0705479 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0704677 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0662108 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0649649 |
| SMAD3 | SMAD family member 3 | 0.0632504 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0630854 |
| CD44 | CD44 molecule (Indian blood group) | 0.0624543 |
| ANXA2 | annexin A2 | 0.0619512 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.061529 |
| DST | dystonin | 0.0609707 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.059183 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0584943 |
| RPS16 | ribosomal protein S16 | 0.0560629 |
| PTK2 | protein tyrosine kinase 2 | 0.0559569 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0535844 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0525698 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0511259 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0487017 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0484922 |
| ATXN1 | ataxin 1 | 0.0482127 |
| JMJD1C | jumonji domain containing 1C | 0.0472735 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0462629 |
| PRELID2 | PRELI domain containing 2 | 0.0460475 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0457438 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0456844 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0447872 |
| SFTPA2 | surfactant protein A2 | 0.0443619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0435789 |
| APP | amyloid beta (A4) precursor protein | 0.0428635 |
| MYOF | myoferlin | 0.040314 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0400673 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0392028 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0391339 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0390687 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0389625 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0386104 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0377915 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0377825 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0374114 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0373585 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0373089 |
| SMYD3 | SET and MYND domain containing 3 | 0.0372952 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0370924 |
| PDE10A | phosphodiesterase 10A | 0.0370514 |
| TNS3 | tensin 3 | 0.0370256 |
| OGA | O-GlcNAcase | 0.0366924 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0366131 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0358994 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0358842 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0357074 |
| RPS8 | ribosomal protein S8 | 0.0354602 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0351347 |
| EFNA5 | ephrin-A5 | 0.0351229 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0342711 |
| NAV2 | neuron navigator 2 | 0.0342002 |
| CARD18 | caspase recruitment domain family, member 18 | 0.0336206 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0332881 |
| ENO1 | enolase 1, (alpha) | 0.033102 |
| NUP98 | nucleoporin 98kDa | 0.0327829 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0326515 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0325229 |
| ANO6 | anoctamin 6 | 0.0323139 |
| FAT1 | FAT atypical cadherin 1 | 0.0321703 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0321155 |
| MED13L | mediator complex subunit 13-like | 0.0319061 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0315086 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0314936 |
| RNF220 | ring finger protein 220 | 0.0312438 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0306379 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0304696 |
| AFAP1 | actin filament associated protein 1 | 0.0304322 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0303942 |
| MCL1 | myeloid cell leukemia 1 | 0.0302549 |
| RAD51B | RAD51 paralog B | 0.0302524 |
| ERBIN | erbb2 interacting protein | 0.0301717 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0295229 |
| PHF14 | PHD finger protein 14 | 0.0291153 |
| MKI67 | marker of proliferation Ki-67 | 0.0290198 |
| CDK19 | cyclin-dependent kinase 19 | 0.0290151 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0287429 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0285726 |
| PLEC | plectin | 0.0285663 |
| CTBP2 | C-terminal binding protein 2 | 0.0283289 |
| CENPF | centromere protein F, 350/400kDa | 0.0281309 |
| FBL | fibrillarin | 0.0280123 |
| AFDN | afadin, adherens junction formation factor | 0.0280094 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.097364 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0594207 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0527301 |
| TMSB10 | thymosin beta 10 | -0.0498007 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0437836 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0360585 |
| VIM | vimentin | -0.034453 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0294247 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0228873 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0210795 |
| PFN1 | profilin 1 | -0.0209225 |
| TMEM41B | transmembrane protein 41B | -0.02001 |
| ZFP36 | ZFP36 ring finger protein | -0.0196035 |
| GOLGA4 | golgin A4 | -0.0193067 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0192328 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0181737 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0173106 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0164771 |
| WASF2 | WAS protein family, member 2 | -0.0159624 |
| SEC24A | SEC24 family member A | -0.0156933 |
| HM13 | histocompatibility (minor) 13 | -0.0146512 |
| TMEM263 | transmembrane protein 263 | -0.0141376 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0140274 |
| NDRG1 | N-myc downstream regulated 1 | -0.0137249 |
| S100A6 | S100 calcium binding protein A6 | -0.0134044 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0132904 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0132753 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0128415 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0124312 |
| SRP54 | signal recognition particle 54kDa | -0.0123611 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0120764 |
| TMEM165 | transmembrane protein 165 | -0.0118052 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.011618 |
| COG6 | component of oligomeric golgi complex 6 | -0.0114744 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0114362 |
| JUN | jun proto-oncogene | -0.0114064 |
| WDR45B | WD repeat domain 45B | -0.0109989 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0109831 |
| DEPP1 | DEPP autophagy regulator 1 | -0.0105824 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0103892 |
| MLF1 | myeloid leukemia factor 1 | -0.0102417 |
| ARF4 | ADP-ribosylation factor 4 | -0.010217 |
| CBX3 | chromobox homolog 3 | -0.0102084 |
| FTL | ferritin, light polypeptide | -0.0100045 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | -0.00972946 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.00963195 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.00947752 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.00916601 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.00905921 |
| COPA | coatomer protein complex, subunit alpha | -0.00899226 |
| MYADM | myeloid-associated differentiation marker | -0.00870209 |
| ERLEC1 | endoplasmic reticulum lectin 1 | -0.00867429 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0086595 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | -0.00857332 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00844805 |
| TPD52 | tumor protein D52 | -0.00844445 |
| RPL8 | ribosomal protein L8 | -0.00839434 |
| HMGA1 | high mobility group AT-hook 1 | -0.00828481 |
| TMF1 | TATA element modulatory factor 1 | -0.00827406 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.00820337 |
| NUCB2 | nucleobindin 2 | -0.00819445 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.00814994 |
| ADM | adrenomedullin | -0.00803992 |
| SRPRA | SRP receptor subunit alpha | -0.00802664 |
| RPL32 | ribosomal protein L32 | -0.00797692 |
| SQLE | squalene epoxidase | -0.00788332 |
| FOSL1 | FOS-like antigen 1 | -0.00780577 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -0.00772897 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.00758662 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.00756567 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.00752884 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0074231 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0073718 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.00735721 |
| SUCO | SUN domain containing ossification factor | -0.00727884 |
| ASTN2 | astrotactin 2 | -0.0072689 |
| UFL1 | UFM1-specific ligase 1 | -0.00708488 |
| SELENOS | selenoprotein S | -0.00700596 |
| PTMA | prothymosin, alpha | -0.00699889 |
| LMAN1 | lectin, mannose-binding, 1 | -0.00694853 |
| COG5 | component of oligomeric golgi complex 5 | -0.00689178 |
| UPP1 | uridine phosphorylase 1 | -0.00680974 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.00675937 |
| SCARB1 | scavenger receptor class B, member 1 | -0.00675425 |
| NKAP | NFKB activating protein | -0.00675217 |
| EGR1 | early growth response 1 | -0.00671606 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.00671448 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.00669874 |
| OSBP | oxysterol binding protein | -0.00669475 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0066481 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.00664185 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.006609 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.00654967 |
| PGM3 | phosphoglucomutase 3 | -0.00648811 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00647719 |
| RAD23A | RAD23 homolog A (S. cerevisiae) | -0.00645146 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.00637902 |
| WBP2 | WW domain binding protein 2 | -0.00632814 |
| MAP4 | microtubule-associated protein 4 | -0.00631374 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.00631167 |
