| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACF1 | microtubule-actin crosslinking factor 1 | 0.11647 |
| FNDC3B | fibronectin type III domain containing 3B | 0.107025 |
| CANX | calnexin | 0.103107 |
| LAMB3 | laminin, beta 3 | 0.0975943 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0940069 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0931682 |
| EMP1 | epithelial membrane protein 1 | 0.0920602 |
| ANXA2 | annexin A2 | 0.0912001 |
| EZR | ezrin | 0.0897598 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0880904 |
| CD2AP | CD2-associated protein | 0.0878393 |
| KRT19 | keratin 19, type I | 0.084052 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.083667 |
| RNF213 | ring finger protein 213 | 0.0809403 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0763647 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0760287 |
| RUNX1 | runt-related transcription factor 1 | 0.0748844 |
| MYO6 | myosin VI | 0.0734012 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0728842 |
| TPM4 | tropomyosin 4 | 0.0712083 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0704965 |
| DSG2 | desmoglein 2 | 0.0690998 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0665887 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0657489 |
| NAV2 | neuron navigator 2 | 0.0651797 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0633383 |
| LMO7 | LIM domain 7 | 0.0612544 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.061086 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0606605 |
| NDRG1 | N-myc downstream regulated 1 | 0.0599944 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0598851 |
| JMJD1C | jumonji domain containing 1C | 0.0590349 |
| FN1 | fibronectin 1 | 0.0589519 |
| PGK1 | phosphoglycerate kinase 1 | 0.0581457 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0577882 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0571211 |
| AHNAK | AHNAK nucleoprotein | 0.0566257 |
| AFDN | afadin, adherens junction formation factor | 0.0563074 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | 0.0557724 |
| SVIL | supervillin | 0.0553345 |
| LAMA4 | laminin, alpha 4 | 0.0552605 |
| CD47 | CD47 molecule | 0.0548914 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0548075 |
| OGA | O-GlcNAcase | 0.0547615 |
| DSPP | dentin sialophosphoprotein | 0.0546084 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0545312 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0538758 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0515934 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0515203 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0513792 |
| XPO1 | exportin 1 | 0.0508243 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0506628 |
| SQSTM1 | sequestosome 1 | 0.0506098 |
| CD44 | CD44 molecule (Indian blood group) | 0.0500949 |
| TMSB4X | thymosin beta 4, X-linked | 0.0500257 |
| TXNIP | thioredoxin interacting protein | 0.049841 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0492623 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0482948 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0482734 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.047094 |
| SMAD3 | SMAD family member 3 | 0.0467757 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0457375 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0454155 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0449948 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0444272 |
| ASPH | aspartate beta-hydroxylase | 0.0433518 |
| RBM39 | RNA binding motif protein 39 | 0.0431454 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0429231 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0427507 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0423104 |
| RIOK3 | RIO kinase 3 | 0.0422138 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0413783 |
| MEF2A | myocyte enhancer factor 2A | 0.0412966 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0412655 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0412618 |
| FLNB | filamin B, beta | 0.0410065 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0408791 |
| TMEM123 | transmembrane protein 123 | 0.0405704 |
| SLMAP | sarcolemma associated protein | 0.0404054 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0401817 |
| KRT18 | keratin 18, type I | 0.0401436 |
| ZNF148 | zinc finger protein 148 | 0.0395536 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0393798 |
| BBX | bobby sox homolog (Drosophila) | 0.0390264 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0383458 |
| MYOF | myoferlin | 0.0383175 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.038032 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0378065 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0375992 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0375829 |
| LDHA | lactate dehydrogenase A | 0.0373563 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.03732 |
| ITGA6 | integrin, alpha 6 | 0.0368962 |
| TSC22D2 | TSC22 domain family, member 2 | 0.036646 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0366034 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0365337 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0356976 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.035365 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0351478 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0350804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.107043 |
| TMSB10 | thymosin beta 10 | -0.0846987 |
| RPL35A | ribosomal protein L35a | -0.0648901 |
| EGR1 | early growth response 1 | -0.0589711 |
| RPS6 | ribosomal protein S6 | -0.0509244 |
| RPS19 | ribosomal protein S19 | -0.0487192 |
| RPL31 | ribosomal protein L31 | -0.0409615 |
| POTEF | POTE ankyrin domain family, member F | -0.0392595 |
| INTS6 | integrator complex subunit 6 | -0.0371866 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0363801 |
| FTL | ferritin, light polypeptide | -0.0360869 |
| RPL23 | ribosomal protein L23 | -0.0352687 |
| RPS23 | ribosomal protein S23 | -0.0349673 |
| ACTG1 | actin gamma 1 | -0.0346641 |
| RPS14 | ribosomal protein S14 | -0.029441 |
| MT2A | metallothionein 2A | -0.0290725 |
| HMGA1 | high mobility group AT-hook 1 | -0.0284688 |
| RASAL2 | RAS protein activator like 2 | -0.027487 |
| RPL28 | ribosomal protein L28 | -0.0272112 |
| RPS8 | ribosomal protein S8 | -0.027166 |
| RPS10 | ribosomal protein S10 | -0.0268418 |
| RPS15 | ribosomal protein S15 | -0.0259081 |
| RPS13 | ribosomal protein S13 | -0.0256431 |
| RPS29 | ribosomal protein S29 | -0.0247887 |
| VCL | vinculin | -0.0244677 |
| RACK1 | receptor for activated C kinase 1 | -0.0239281 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0235901 |
| RPLP2 | ribosomal protein, large, P2 | -0.0234334 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0220953 |
| RPS16 | ribosomal protein S16 | -0.0215569 |
| WWC1 | WW and C2 domain containing 1 | -0.0205937 |
| SLC38A2 | solute carrier family 38, member 2 | -0.020062 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0199632 |
| RPL37 | ribosomal protein L37 | -0.0198255 |
| RPL10A | ribosomal protein L10a | -0.0197463 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0196301 |
| RPL37A | ribosomal protein L37a | -0.0193851 |
| RPS11 | ribosomal protein S11 | -0.0193411 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0183706 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0171236 |
| RPS24 | ribosomal protein S24 | -0.0169773 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 | -0.0169722 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.01641 |
| RPL27 | ribosomal protein L27 | -0.0162882 |
| NABP1 | nucleic acid binding protein 1 | -0.016232 |
| RPS25 | ribosomal protein S25 | -0.0161688 |
| PFN1 | profilin 1 | -0.015842 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0158117 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0154292 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0152842 |
| RPS21 | ribosomal protein S21 | -0.0151855 |
| RPS20 | ribosomal protein S20 | -0.015053 |
| RPS5 | ribosomal protein S5 | -0.0149231 |
| RPL36 | ribosomal protein L36 | -0.0146064 |
| RPL21 | ribosomal protein L21 | -0.0145349 |
| RPS28 | ribosomal protein S28 | -0.0143661 |
| RPL32 | ribosomal protein L32 | -0.0142536 |
| AREG | amphiregulin | -0.0141467 |
| RPL34 | ribosomal protein L34 | -0.0136525 |
| PLK2 | polo-like kinase 2 | -0.0135703 |
| IER2 | immediate early response 2 | -0.0135337 |
| RPS17 | ribosomal protein S17 | -0.0133609 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0131537 |
| PTK2B | protein tyrosine kinase 2 beta | -0.0130838 |
| RPL27A | ribosomal protein L27a | -0.013063 |
| TBCA | tubulin folding cofactor A | -0.0130603 |
| MUC4 | mucin 4, cell surface associated | -0.0129164 |
| LATS2 | large tumor suppressor kinase 2 | -0.0127785 |
| ASTN2 | astrotactin 2 | -0.012684 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0126711 |
| RPS27A | ribosomal protein S27a | -0.0125036 |
| ATF4 | activating transcription factor 4 | -0.0123199 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0122 |
| THBS1 | thrombospondin 1 | -0.0120931 |
| RPL5 | ribosomal protein L5 | -0.0120383 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.012024 |
| BCL2L1 | BCL2-like 1 | -0.0116121 |
| COG6 | component of oligomeric golgi complex 6 | -0.0116109 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0115443 |
| RPL7A | ribosomal protein L7a | -0.0115246 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0114446 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0114345 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0113905 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | -0.0112853 |
| TGFA | transforming growth factor, alpha | -0.0111886 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0110971 |
| KRT86 | keratin 86, type II | -0.0110253 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0109319 |
| RPL8 | ribosomal protein L8 | -0.0106665 |
| TKT | transketolase | -0.0105631 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0104664 |
| DIAPH3 | diaphanous-related formin 3 | -0.0104104 |
| PCNX4 | pecanex 4 | -0.0103904 |
| HOMER1 | homer scaffolding protein 1 | -0.010309 |
| S100A9 | S100 calcium binding protein A9 | -0.0102919 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0102542 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0102006 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0101799 |
| RPL36AL | ribosomal protein L36a-like | -0.010074 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.00998466 |
