| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Methylprednisolone succinate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.209944 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0971626 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0789615 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0744088 |
| PGK1 | phosphoglycerate kinase 1 | 0.0703199 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0563543 |
| FAM20C | family with sequence similarity 20, member C | 0.0520069 |
| RBM39 | RNA binding motif protein 39 | 0.0514723 |
| FNDC3B | fibronectin type III domain containing 3B | 0.049639 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0492712 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0479419 |
| AFAP1 | actin filament associated protein 1 | 0.0463793 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0458627 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0451642 |
| YEATS2 | YEATS domain containing 2 | 0.0412592 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0394352 |
| ZNF292 | zinc finger protein 292 | 0.0392176 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0384371 |
| CENPF | centromere protein F, 350/400kDa | 0.0381201 |
| AHNAK | AHNAK nucleoprotein | 0.0378664 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0373093 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0352314 |
| OGA | O-GlcNAcase | 0.0351838 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0348897 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0340933 |
| FMNL2 | formin-like 2 | 0.0323577 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0320271 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0315718 |
| SMAD3 | SMAD family member 3 | 0.0311216 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0309733 |
| NAV2 | neuron navigator 2 | 0.0308437 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.03077 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.030675 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0305335 |
| TGM2 | transglutaminase 2 | 0.030469 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0304628 |
| RLIM | ring finger protein, LIM domain interacting | 0.0301626 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0296461 |
| FLNB | filamin B, beta | 0.0295132 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0289469 |
| ASPH | aspartate beta-hydroxylase | 0.0288898 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0285462 |
| XPO1 | exportin 1 | 0.0283751 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0279368 |
| PTK2 | protein tyrosine kinase 2 | 0.0274183 |
| AFDN | afadin, adherens junction formation factor | 0.0272288 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0272262 |
| COPA | coatomer protein complex, subunit alpha | 0.0269377 |
| CANX | calnexin | 0.0269288 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0266462 |
| ANLN | anillin, actin binding protein | 0.0265159 |
| ZNF148 | zinc finger protein 148 | 0.0262481 |
| NCKAP1 | NCK-associated protein 1 | 0.0257895 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0251715 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0251138 |
| ACTN4 | actinin, alpha 4 | 0.0249436 |
| APP | amyloid beta (A4) precursor protein | 0.0246395 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0245518 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.024499 |
| CENPE | centromere protein E, 312kDa | 0.0243297 |
| PLEC | plectin | 0.0242077 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0239885 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0237513 |
| CEP250 | centrosomal protein 250kDa | 0.0236643 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0236364 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0235278 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234752 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0234323 |
| CALU | calumenin | 0.0234251 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0231929 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0231503 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0229649 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0229023 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0228559 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.022713 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.022546 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0224421 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.022044 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0218944 |
| ZNF654 | zinc finger protein 654 | 0.0218262 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0217206 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0214969 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.021403 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.021224 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0210187 |
| NCAM1 | neural cell adhesion molecule 1 | 0.0209981 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0208108 |
| MLPH | melanophilin | 0.0208056 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0206477 |
| KIAA1328 | KIAA1328 | 0.0206115 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0205693 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0204825 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.020451 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0202799 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0201687 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0201144 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0201139 |
| CD109 | CD109 molecule | 0.0201103 |
| ZNF638 | zinc finger protein 638 | 0.0200352 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0199628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.170971 |
| FTL | ferritin, light polypeptide | -0.163084 |
| TMSB10 | thymosin beta 10 | -0.130092 |
| B2M | beta-2-microglobulin | -0.124841 |
| HLA-B | major histocompatibility complex, class I, B | -0.120379 |
| COL1A1 | collagen, type I, alpha 1 | -0.120149 |
| COL1A2 | collagen, type I, alpha 2 | -0.110495 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.109944 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0958154 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0906888 |
| STC1 | stanniocalcin 1 | -0.0826796 |
| INHBA | inhibin, beta A | -0.0760248 |
| CDH13 | cadherin 13 | -0.0713245 |
| IL1B | interleukin 1, beta | -0.0669739 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0639731 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0620648 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0583576 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0578075 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0536465 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0512955 |
| RAB7A | RAB7A, member RAS oncogene family | -0.050641 |
| IER3 | immediate early response 3 | -0.0497763 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0493188 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0477296 |
| POTEF | POTE ankyrin domain family, member F | -0.0475437 |
| SP100 | SP100 nuclear antigen | -0.0473747 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0465758 |
| NAV1 | neuron navigator 1 | -0.0463811 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0459006 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0456759 |
| COL6A2 | collagen, type VI, alpha 2 | -0.044587 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0445675 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0429965 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0429063 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.041528 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | -0.0414858 |
| EGR1 | early growth response 1 | -0.0413659 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0410977 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0404363 |
| RPS19 | ribosomal protein S19 | -0.0398756 |
| MT2A | metallothionein 2A | -0.0394459 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0393113 |
| RPL35A | ribosomal protein L35a | -0.0369173 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0367946 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0356412 |
| S100A6 | S100 calcium binding protein A6 | -0.0356377 |
| PFN1 | profilin 1 | -0.0351562 |
| RPS6 | ribosomal protein S6 | -0.0349066 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0346744 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0330425 |
| ADM | adrenomedullin | -0.032461 |
| C1R | complement component 1, r subcomponent | -0.0323801 |
| RRBP1 | ribosome binding protein 1 | -0.0323141 |
| HLA-A | major histocompatibility complex, class I, A | -0.0319315 |
| RPLP2 | ribosomal protein, large, P2 | -0.0304434 |
| POU2F2 | POU class 2 homeobox 2 | -0.0303421 |
| RPS21 | ribosomal protein S21 | -0.0301696 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301272 |
| NRP1 | neuropilin 1 | -0.0297858 |
| RPL28 | ribosomal protein L28 | -0.0293305 |
| FHIT | fragile histidine triad | -0.029175 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0291147 |
| S100A9 | S100 calcium binding protein A9 | -0.0284168 |
| NDRG1 | N-myc downstream regulated 1 | -0.0278114 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0271731 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0271443 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.026977 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0268736 |
| SERF2 | small EDRK-rich factor 2 | -0.0268181 |
| RPL32 | ribosomal protein L32 | -0.0264839 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0261325 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0260888 |
| GLIS3 | GLIS family zinc finger 3 | -0.0259768 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0255571 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0255103 |
| FRMD4A | FERM domain containing 4A | -0.0254783 |
| ARMC9 | armadillo repeat containing 9 | -0.0254704 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.025145 |
| RPS17 | ribosomal protein S17 | -0.0251138 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0249031 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.024875 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.024748 |
| CST3 | cystatin C | -0.0245846 |
| S100A10 | S100 calcium binding protein A10 | -0.0241846 |
| FOSL1 | FOS-like antigen 1 | -0.0240933 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0238113 |
| RPS14 | ribosomal protein S14 | -0.0235631 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0235222 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0234442 |
| CADM1 | cell adhesion molecule 1 | -0.0233945 |
| ITGA11 | integrin, alpha 11 | -0.023291 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0232053 |
| MFSD12 | major facilitator superfamily domain containing 12 | -0.0229162 |
| TNS3 | tensin 3 | -0.0228633 |
| RPL23 | ribosomal protein L23 | -0.0226809 |
| RNASEH2A | ribonuclease H2, subunit A | -0.02262 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0225636 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0224082 |
| GNAS | GNAS complex locus | -0.0223777 |
| TGFB1 | transforming growth factor, beta 1 | -0.0218719 |
