| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0980538 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0947696 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0941016 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0846886 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.079283 |
| GOLGA4 | golgin A4 | 0.0781758 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.074983 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0747594 |
| FLNB | filamin B, beta | 0.0735889 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0693714 |
| RBM39 | RNA binding motif protein 39 | 0.0683063 |
| TJP1 | tight junction protein 1 | 0.0670724 |
| ZNF292 | zinc finger protein 292 | 0.0645237 |
| EZR | ezrin | 0.0641969 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0569752 |
| RTN4 | reticulon 4 | 0.0546346 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0543038 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0533086 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0523055 |
| TXNRD1 | thioredoxin reductase 1 | 0.0507376 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.049113 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0482104 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0479232 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0475829 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0473952 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0471249 |
| NUP58 | nucleoporin 58 | 0.0463959 |
| EVI5 | ecotropic viral integration site 5 | 0.0455388 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.044776 |
| JMJD1C | jumonji domain containing 1C | 0.0446326 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.044286 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0438965 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0435321 |
| NBAS | neuroblastoma amplified sequence | 0.0435194 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0430529 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0430378 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0428697 |
| ECT2 | epithelial cell transforming 2 | 0.0424565 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0416527 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.041154 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0409834 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0409491 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.040806 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0403903 |
| QKI | QKI, KH domain containing, RNA binding | 0.0403384 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0401299 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0399853 |
| ANK2 | ankyrin 2, neuronal | 0.0398897 |
| LDHA | lactate dehydrogenase A | 0.0397707 |
| SBF2 | SET binding factor 2 | 0.0395262 |
| SETD5 | SET domain containing 5 | 0.0379577 |
| NCKAP1 | NCK-associated protein 1 | 0.0377881 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0377723 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0377155 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0372519 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.037225 |
| RNF145 | ring finger protein 145 | 0.0366373 |
| COG5 | component of oligomeric golgi complex 5 | 0.0366005 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0365696 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0365481 |
| TFG | TRK-fused gene | 0.0365353 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0362004 |
| CDC73 | cell division cycle 73 | 0.0360821 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0358239 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0354933 |
| TMEM41B | transmembrane protein 41B | 0.0354614 |
| PDGFC | platelet derived growth factor C | 0.0354316 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0349514 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0348239 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0348059 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0346269 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0345353 |
| CCNL1 | cyclin L1 | 0.0342684 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0339498 |
| HDAC9 | histone deacetylase 9 | 0.0333308 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0329706 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0329518 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0328456 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0328078 |
| HDLBP | high density lipoprotein binding protein | 0.0325905 |
| PCBP2 | poly(rC) binding protein 2 | 0.0323152 |
| NF1 | neurofibromin 1 | 0.0321209 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0320742 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0314071 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0308203 |
| PTK2 | protein tyrosine kinase 2 | 0.0300711 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0298972 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0298357 |
| MED13L | mediator complex subunit 13-like | 0.0297953 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0297868 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0296647 |
| CD47 | CD47 molecule | 0.0295903 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0295626 |
| TXNIP | thioredoxin interacting protein | 0.0292992 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0292296 |
| COPA | coatomer protein complex, subunit alpha | 0.0283229 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0283115 |
| SRPK2 | SRSF protein kinase 2 | 0.0281793 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0275533 |
| COG6 | component of oligomeric golgi complex 6 | 0.0275266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP10 | bone morphogenetic protein 10 | -0.0771029 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0587774 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0546643 |
| RPL35A | ribosomal protein L35a | -0.0464581 |
| MKI67 | marker of proliferation Ki-67 | -0.0351517 |
| RPS6 | ribosomal protein S6 | -0.0341039 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0301277 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260922 |
| CCND1 | cyclin D1 | -0.0241703 |
| RPL31 | ribosomal protein L31 | -0.0241326 |
| RPS8 | ribosomal protein S8 | -0.0239157 |
| RPL34 | ribosomal protein L34 | -0.0236316 |
| NAV2 | neuron navigator 2 | -0.0233758 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0225003 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0221448 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0220937 |
| S100A4 | S100 calcium binding protein A4 | -0.0212976 |
| RPLP2 | ribosomal protein, large, P2 | -0.0208115 |
| MYO5C | myosin VC | -0.020739 |
| RPL37A | ribosomal protein L37a | -0.0201697 |
| GLI3 | GLI family zinc finger 3 | -0.0194995 |
| RPS27A | ribosomal protein S27a | -0.0193178 |
| ACTG1 | actin gamma 1 | -0.0192832 |
| RPS12 | ribosomal protein S12 | -0.0186322 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0185548 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0181215 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0163812 |
| RACK1 | receptor for activated C kinase 1 | -0.016357 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0162306 |
| TMSB10 | thymosin beta 10 | -0.0153496 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0151232 |
| ZNF438 | zinc finger protein 438 | -0.0149634 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0148143 |
| RPL38 | ribosomal protein L38 | -0.0148038 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0146712 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0146609 |
| RPL4 | ribosomal protein L4 | -0.0144155 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0144092 |
| S100A10 | S100 calcium binding protein A10 | -0.0144009 |
| MACROD2 | MACRO domain containing 2 | -0.0143639 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0142227 |
| BCOR | BCL6 corepressor | -0.0142151 |
| EMP3 | epithelial membrane protein 3 | -0.0141794 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0139436 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0137712 |
| RPL7A | ribosomal protein L7a | -0.0135175 |
| RPS24 | ribosomal protein S24 | -0.0135134 |
| RPS19 | ribosomal protein S19 | -0.0134356 |
| RPL9 | ribosomal protein L9 | -0.0132874 |
| THBD | thrombomodulin | -0.0132455 |
| RPS4X | ribosomal protein S4, X-linked | -0.0132335 |
| RPS14 | ribosomal protein S14 | -0.0131424 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0129109 |
| HMGB1 | high mobility group box 1 | -0.0126325 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0125566 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0122172 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0122084 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0121693 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.012141 |
| DIAPH3 | diaphanous-related formin 3 | -0.0121285 |
| CUX1 | cut-like homeobox 1 | -0.0119094 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0118238 |
| ITGA10 | integrin, alpha 10 | -0.0118019 |
| RPL36A | ribosomal protein L36a | -0.0117187 |
| UBB | ubiquitin B | -0.0116636 |
| RPL26 | ribosomal protein L26 | -0.0114276 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0114138 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0114072 |
| GSE1 | Gse1 coiled-coil protein | -0.0112914 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0111859 |
| PDE7B | phosphodiesterase 7B | -0.0111586 |
| TUBA1B | tubulin, alpha 1b | -0.0110992 |
| S100A9 | S100 calcium binding protein A9 | -0.0109177 |
| APLF | aprataxin and PNKP like factor | -0.0108312 |
| RPS13 | ribosomal protein S13 | -0.0108159 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0102491 |
| RPS16 | ribosomal protein S16 | -0.0102276 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.010196 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00998476 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.00993002 |
| FTL | ferritin, light polypeptide | -0.00986019 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00985141 |
| RPL23 | ribosomal protein L23 | -0.00973699 |
| CENPF | centromere protein F, 350/400kDa | -0.00971399 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.00961782 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.00953468 |
| ASTN2 | astrotactin 2 | -0.00951495 |
| RPL19 | ribosomal protein L19 | -0.00947447 |
| STMN1 | stathmin 1 | -0.00946855 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.00945299 |
| RPL36 | ribosomal protein L36 | -0.00941353 |
| RRM2 | ribonucleotide reductase M2 | -0.00934447 |
| CEP112 | centrosomal protein 112kDa | -0.00932794 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00927048 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.00922625 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.00918546 |
| RPLP0 | ribosomal protein, large, P0 | -0.00915307 |
| RPL30 | ribosomal protein L30 | -0.00903362 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0090296 |
| FER1L6 | fer-1-like family member 6 | -0.0089881 |
