| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.214925 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.178511 |
| FNDC3B | fibronectin type III domain containing 3B | 0.139918 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.120429 |
| PDE10A | phosphodiesterase 10A | 0.111285 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.101302 |
| NAV2 | neuron navigator 2 | 0.101125 |
| DST | dystonin | 0.100289 |
| CADM1 | cell adhesion molecule 1 | 0.0965423 |
| FRMD4A | FERM domain containing 4A | 0.0960933 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0933077 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0796473 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0792699 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0777769 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.075615 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0744578 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0714223 |
| SFTPA2 | surfactant protein A2 | 0.0684009 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.064332 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0627704 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0624109 |
| MSN | moesin | 0.0611429 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0588417 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0587736 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0576759 |
| ATXN1 | ataxin 1 | 0.0561589 |
| ZNF292 | zinc finger protein 292 | 0.0558355 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0556536 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0553336 |
| OGA | O-GlcNAcase | 0.0552414 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0551058 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0545306 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0532411 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0515186 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.050962 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0504856 |
| TNS3 | tensin 3 | 0.0495834 |
| CANX | calnexin | 0.0479759 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0479668 |
| SEPTIN9 | septin 9 | 0.0479261 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0478786 |
| FNIP1 | folliculin interacting protein 1 | 0.0477186 |
| FLNB | filamin B, beta | 0.0468214 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0449022 |
| VCAN | versican | 0.0443421 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0441931 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0433268 |
| MYOF | myoferlin | 0.0430483 |
| RBM39 | RNA binding motif protein 39 | 0.0425823 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.042455 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0422177 |
| CEP250 | centrosomal protein 250kDa | 0.0418909 |
| SMAD3 | SMAD family member 3 | 0.0414456 |
| NDRG1 | N-myc downstream regulated 1 | 0.0414191 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0410201 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0405767 |
| CD44 | CD44 molecule (Indian blood group) | 0.0400054 |
| JMJD1C | jumonji domain containing 1C | 0.0389712 |
| SPAG9 | sperm associated antigen 9 | 0.0388676 |
| ANXA2 | annexin A2 | 0.0385385 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0384489 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0383363 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0383296 |
| PGK1 | phosphoglycerate kinase 1 | 0.0382404 |
| VMP1 | vacuole membrane protein 1 | 0.0381009 |
| PCBP2 | poly(rC) binding protein 2 | 0.0378988 |
| PRELID2 | PRELI domain containing 2 | 0.0373896 |
| VIM | vimentin | 0.0371197 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.036483 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0353434 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0351696 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0348323 |
| ATP13A3 | ATPase type 13A3 | 0.0344825 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0342963 |
| GLIS3 | GLIS family zinc finger 3 | 0.0342547 |
| TPM4 | tropomyosin 4 | 0.0342434 |
| SETD5 | SET domain containing 5 | 0.0341384 |
| GOLGA4 | golgin A4 | 0.034044 |
| ADM | adrenomedullin | 0.0335381 |
| DIAPH2 | diaphanous-related formin 2 | 0.0334967 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0333065 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0331122 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0330025 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0327041 |
| RTN4 | reticulon 4 | 0.0326081 |
| YEATS2 | YEATS domain containing 2 | 0.032182 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0321743 |
| LDHA | lactate dehydrogenase A | 0.0319188 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0318429 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0317692 |
| HDAC9 | histone deacetylase 9 | 0.0317394 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0312518 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0311451 |
| FMNL2 | formin-like 2 | 0.031053 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0308102 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0306691 |
| CDK19 | cyclin-dependent kinase 19 | 0.0305386 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0299558 |
| CLIC4 | chloride intracellular channel 4 | 0.0298361 |
| CDH13 | cadherin 13 | 0.0290607 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0536174 |
| IER3 | immediate early response 3 | -0.0405988 |
| FTL | ferritin, light polypeptide | -0.0302652 |
| MT2A | metallothionein 2A | -0.0281646 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0262355 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0255632 |
| GPC6 | glypican 6 | -0.0237906 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0199497 |
| RPL35A | ribosomal protein L35a | -0.0192005 |
| RPS19 | ribosomal protein S19 | -0.0190588 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0184958 |
| RPL4 | ribosomal protein L4 | -0.0174219 |
| RPS24 | ribosomal protein S24 | -0.0163572 |
| RPS12 | ribosomal protein S12 | -0.0162974 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0138435 |
| RPL36A | ribosomal protein L36a | -0.0132659 |
| RPL36 | ribosomal protein L36 | -0.0127904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0124712 |
| RPL37A | ribosomal protein L37a | -0.0123161 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0116772 |
| ATF4 | activating transcription factor 4 | -0.0114252 |
| RPLP2 | ribosomal protein, large, P2 | -0.0106639 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0105905 |
| RPL7A | ribosomal protein L7a | -0.0105437 |
| RPL31 | ribosomal protein L31 | -0.0103748 |
| GNAS | GNAS complex locus | -0.0100893 |
| TMSB4X | thymosin beta 4, X-linked | -0.00979039 |
| RPS4X | ribosomal protein S4, X-linked | -0.00956925 |
| RPL37 | ribosomal protein L37 | -0.00905653 |
| RPL14 | ribosomal protein L14 | -0.00889006 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00885577 |
| RPLP1 | ribosomal protein, large, P1 | -0.00880975 |
| ARF1 | ADP-ribosylation factor 1 | -0.00876266 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00870897 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0086768 |
| RPS28 | ribosomal protein S28 | -0.00867384 |
| RPL6 | ribosomal protein L6 | -0.00859772 |
| DUSP12 | dual specificity phosphatase 12 | -0.00845689 |
| RPL28 | ribosomal protein L28 | -0.00787423 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.00760066 |
| HMGB1 | high mobility group box 1 | -0.0075582 |
| RPS14 | ribosomal protein S14 | -0.00749909 |
| GM2A | GM2 ganglioside activator | -0.00739541 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.00739074 |
| ADIPOR1 | adiponectin receptor 1 | -0.00727365 |
| MT1X | metallothionein 1X | -0.00722532 |
| RPS27A | ribosomal protein S27a | -0.00708979 |
| NTN4 | netrin 4 | -0.00698367 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00697384 |
| RPL12 | ribosomal protein L12 | -0.00693485 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.00691587 |
| RPS3 | ribosomal protein S3 | -0.00690049 |
| RPL26 | ribosomal protein L26 | -0.00687495 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00685736 |
| RPL38 | ribosomal protein L38 | -0.00673849 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0066569 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | -0.00664224 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00646678 |
| RPL23A | ribosomal protein L23a | -0.00644232 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00631975 |
| BSG | basigin (Ok blood group) | -0.00624297 |
| CTSD | cathepsin D | -0.00621267 |
| RPL34 | ribosomal protein L34 | -0.0062126 |
| RPS21 | ribosomal protein S21 | -0.00620381 |
| ZC3H11D | zinc finger CCCH-type containing 11D | -0.00620325 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | -0.00614956 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.00614272 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 | -0.00611058 |
| PFDN4 | prefoldin subunit 4 | -0.00609102 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00598777 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.00582012 |
| GALC | galactosylceramidase | -0.00580949 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00578972 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.00578496 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0057796 |
| ZNF493 | zinc finger protein 493 | -0.00573878 |
| RPL18 | ribosomal protein L18 | -0.0057303 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G | -0.00567034 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.00566302 |
| RPL35 | ribosomal protein L35 | -0.00563485 |
| UBB | ubiquitin B | -0.00562269 |
| RPL32 | ribosomal protein L32 | -0.00561197 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00558101 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 | -0.00556306 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.00552956 |
| GABARAP | GABA(A) receptor-associated protein | -0.00552772 |
| HMGB2 | high mobility group box 2 | -0.0055072 |
| H1-4 | H1.4 linker histone, cluster member | -0.00548785 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.00547695 |
| MIDN | midnolin | -0.00542881 |
| PFN1 | profilin 1 | -0.00539497 |
| CAVIN1 | caveolae associated protein 1 | -0.00537794 |
| POTEF | POTE ankyrin domain family, member F | -0.00533106 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00531684 |
| CPM | carboxypeptidase M | -0.00528248 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.00522809 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00521508 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00519081 |
| ATXN2L | ataxin 2-like | -0.0051719 |
| PEBP1 | phosphatidylethanolamine binding protein 1 | -0.00513875 |
