| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.218403 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0718331 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0635964 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0615956 |
| CANX | calnexin | 0.0614393 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0581658 |
| ANXA2 | annexin A2 | 0.0566692 |
| THBS1 | thrombospondin 1 | 0.056259 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0556337 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0509852 |
| NRXN3 | neurexin 3 | 0.049806 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0497658 |
| DST | dystonin | 0.0469357 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0458219 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0458005 |
| TNS3 | tensin 3 | 0.0455127 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446365 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0440062 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0429839 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0426161 |
| OGA | O-GlcNAcase | 0.042265 |
| COL5A1 | collagen, type V, alpha 1 | 0.042037 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0411261 |
| CD44 | CD44 molecule (Indian blood group) | 0.0410502 |
| ACTN4 | actinin, alpha 4 | 0.040456 |
| AHNAK | AHNAK nucleoprotein | 0.0400647 |
| FN1 | fibronectin 1 | 0.0394532 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0386166 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0380723 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0370665 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.036855 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0365486 |
| COL1A2 | collagen, type I, alpha 2 | 0.0354316 |
| PRKCA | protein kinase C, alpha | 0.0347784 |
| VEGFC | vascular endothelial growth factor C | 0.034752 |
| GLIS3 | GLIS family zinc finger 3 | 0.0344359 |
| HMGA2 | high mobility group AT-hook 2 | 0.0343265 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0342319 |
| PRSS23 | protease, serine, 23 | 0.0336172 |
| GRB10 | growth factor receptor-bound protein 10 | 0.033229 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0329328 |
| RBM39 | RNA binding motif protein 39 | 0.0327912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0327479 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0322589 |
| MAP1B | microtubule-associated protein 1B | 0.032195 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0318035 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0312763 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0308971 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0306562 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0302018 |
| ITGA6 | integrin, alpha 6 | 0.029862 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0296641 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0293178 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0290734 |
| ADNP | activity-dependent neuroprotector homeobox | 0.028876 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.028776 |
| EGFR | epidermal growth factor receptor | 0.0286037 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.028594 |
| PUM2 | pumilio RNA-binding family member 2 | 0.028531 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0283673 |
| SETBP1 | SET binding protein 1 | 0.0276756 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0275196 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0272204 |
| PTK2 | protein tyrosine kinase 2 | 0.0269616 |
| MED13L | mediator complex subunit 13-like | 0.0268449 |
| PDGFC | platelet derived growth factor C | 0.0266843 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0263433 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0261294 |
| VMP1 | vacuole membrane protein 1 | 0.0258826 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0258352 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0257396 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0255214 |
| JAK1 | Janus kinase 1 | 0.0253392 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0251799 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0251711 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0251614 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0249265 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0245696 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0243931 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0242805 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0241014 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0240774 |
| NRP1 | neuropilin 1 | 0.0240511 |
| MCL1 | myeloid cell leukemia 1 | 0.0238938 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0237627 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0235991 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0233359 |
| MORF4L2 | mortality factor 4 like 2 | 0.0231847 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.023086 |
| CCND1 | cyclin D1 | 0.0229957 |
| AUTS2 | autism susceptibility candidate 2 | 0.0226638 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0226586 |
| FLNB | filamin B, beta | 0.0224404 |
| TMEM263 | transmembrane protein 263 | 0.0224132 |
| SEPTIN11 | septin 11 | 0.0224095 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0223731 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0222543 |
| PHF21A | PHD finger protein 21A | 0.0221568 |
| CTBP2 | C-terminal binding protein 2 | 0.0221222 |
| MATR3 | matrin 3 | 0.022079 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.177072 |
| TMSB10 | thymosin beta 10 | -0.105739 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0760588 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644645 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0614384 |
| FTL | ferritin, light polypeptide | -0.0559548 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0500345 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0481739 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.042973 |
| NDRG1 | N-myc downstream regulated 1 | -0.0376266 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0361852 |
| SEPTIN7 | septin 7 | -0.0360884 |
| RPS14 | ribosomal protein S14 | -0.0345888 |
| POTEF | POTE ankyrin domain family, member F | -0.0339776 |
| ADM | adrenomedullin | -0.0333533 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0312851 |
| COL1A1 | collagen, type I, alpha 1 | -0.0309333 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0308812 |
| HLA-B | major histocompatibility complex, class I, B | -0.0292458 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0287879 |
| KIF1B | kinesin family member 1B | -0.0283806 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0276292 |
| TGFB1 | transforming growth factor, beta 1 | -0.0268017 |
| CAVIN1 | caveolae associated protein 1 | -0.0253394 |
| XPO1 | exportin 1 | -0.0253158 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0252631 |
| ATF4 | activating transcription factor 4 | -0.0242503 |
| CADM1 | cell adhesion molecule 1 | -0.0240857 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0240102 |
| NUMB | numb homolog (Drosophila) | -0.0233279 |
| DSTN | destrin (actin depolymerizing factor) | -0.0230913 |
| B2M | beta-2-microglobulin | -0.0224804 |
| RAP1A | RAP1A, member of RAS oncogene family | -0.0224779 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0219561 |
| POT1 | protection of telomeres 1 | -0.0218706 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0210738 |
| S100A6 | S100 calcium binding protein A6 | -0.0208873 |
| RPLP1 | ribosomal protein, large, P1 | -0.0204211 |
| RPL23 | ribosomal protein L23 | -0.0203069 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0202998 |
| RBMX | RNA binding motif protein, X-linked | -0.0202759 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0202058 |
| RPL31 | ribosomal protein L31 | -0.020201 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0197445 |
| C1R | complement component 1, r subcomponent | -0.0195671 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.01944 |
| RPL7A | ribosomal protein L7a | -0.0193792 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0192052 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0189235 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0188031 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0186538 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0186062 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0185434 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0183047 |
| RPL37 | ribosomal protein L37 | -0.0182716 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0182071 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0181268 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0178793 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0177955 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0177408 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0177108 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) | -0.0176779 |
| PXDN | peroxidasin | -0.0176337 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0174503 |
| ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 | -0.0174479 |
| RPS25 | ribosomal protein S25 | -0.017357 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0173284 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.0172935 |
| SNX3 | sorting nexin 3 | -0.017183 |
| UPP1 | uridine phosphorylase 1 | -0.017151 |
| RPS19 | ribosomal protein S19 | -0.0171332 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 | -0.0170757 |
| VEGFA | vascular endothelial growth factor A | -0.0170325 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0169908 |
| RACK1 | receptor for activated C kinase 1 | -0.01689 |
| RAB5A | RAB5A, member RAS oncogene family | -0.016844 |
| SRP54 | signal recognition particle 54kDa | -0.0166853 |
| TBCA | tubulin folding cofactor A | -0.0163922 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0163875 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | -0.0163578 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0163195 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.016278 |
| RPS6 | ribosomal protein S6 | -0.0162723 |
| ZNF146 | zinc finger protein 146 | -0.0162514 |
| RPL37A | ribosomal protein L37a | -0.0161417 |
| RRBP1 | ribosome binding protein 1 | -0.0160531 |
| RPS23 | ribosomal protein S23 | -0.0160114 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0159799 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0159261 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0159241 |
| EGR1 | early growth response 1 | -0.0158494 |
| POMP | proteasome maturation protein | -0.0158352 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0158227 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0158215 |
| AFTPH | aftiphilin | -0.0158194 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0158105 |
| MVP | major vault protein | -0.0157691 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0156181 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0155896 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0155891 |
