| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Methylprednisolone succinate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.114448 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0915965 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0815639 |
| SPAG9 | sperm associated antigen 9 | 0.0757078 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0657206 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0637905 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0608535 |
| CCDC88A | coiled-coil domain containing 88A | 0.0551356 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0544128 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0543855 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0543696 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0521035 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.052054 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0510419 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0510067 |
| ENO1 | enolase 1, (alpha) | 0.0503821 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0502829 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0500068 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0499813 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0485105 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0475587 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0475288 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0474959 |
| CAPRIN2 | caprin family member 2 | 0.0468093 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0464505 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0462402 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.045891 |
| YBX3 | Y box binding protein 3 | 0.0457237 |
| ERBIN | erbb2 interacting protein | 0.044569 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0436755 |
| TXNIP | thioredoxin interacting protein | 0.0424 |
| PYGL | phosphorylase, glycogen, liver | 0.0421773 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0421383 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0418121 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0413843 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0411163 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0410593 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0403069 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0401857 |
| EGFR | epidermal growth factor receptor | 0.0397948 |
| FLNB | filamin B, beta | 0.0396822 |
| KIF5B | kinesin family member 5B | 0.0395234 |
| EXOC4 | exocyst complex component 4 | 0.0384207 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0382429 |
| CEP250 | centrosomal protein 250kDa | 0.0381766 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0381003 |
| LMO7 | LIM domain 7 | 0.0380657 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0373579 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0371212 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0370511 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0365609 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.036375 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0361471 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0357978 |
| DST | dystonin | 0.0356726 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0355168 |
| NAV2 | neuron navigator 2 | 0.0350619 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0344455 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0340699 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0339195 |
| CDK19 | cyclin-dependent kinase 19 | 0.033769 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0337354 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0333811 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0331225 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0329888 |
| DOCK4 | dedicator of cytokinesis 4 | 0.032724 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0327214 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0326859 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0326832 |
| RUNX1 | runt-related transcription factor 1 | 0.0324209 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.032051 |
| PRKCE | protein kinase C, epsilon | 0.0319162 |
| APP | amyloid beta (A4) precursor protein | 0.0317904 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.031627 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0315941 |
| ANXA2 | annexin A2 | 0.0315668 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0313948 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0313134 |
| RBM33 | RNA binding motif protein 33 | 0.0311505 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0310874 |
| RSF1 | remodeling and spacing factor 1 | 0.0310102 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0309646 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0306514 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0306048 |
| TAOK1 | TAO kinase 1 | 0.0301517 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.030051 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0300409 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0299067 |
| INTS6 | integrator complex subunit 6 | 0.0295763 |
| EZR | ezrin | 0.0295056 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0294557 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.029446 |
| CEP295 | centrosomal protein 295kDa | 0.0294277 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0291883 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0290275 |
| OXSR1 | oxidative stress responsive 1 | 0.0287485 |
| CUL5 | cullin 5 | 0.0284302 |
| HBS1L | HBS1-like translational GTPase | 0.0283037 |
| TRIM44 | tripartite motif containing 44 | 0.0282072 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0280973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.1104 |
| TMSB10 | thymosin beta 10 | -0.102653 |
| VIM | vimentin | -0.0695714 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0504435 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0455175 |
| RPL35A | ribosomal protein L35a | -0.0449957 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0431234 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0428695 |
| HMGA2 | high mobility group AT-hook 2 | -0.0426872 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0390186 |
| S100A10 | S100 calcium binding protein A10 | -0.0385954 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0378116 |
| UBB | ubiquitin B | -0.0365025 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345167 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0338023 |
| RPL4 | ribosomal protein L4 | -0.0334805 |
| ETF1 | eukaryotic translation termination factor 1 | -0.0334249 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.03335 |
| RPLP1 | ribosomal protein, large, P1 | -0.0322693 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0315889 |
| CEP95 | centrosomal protein 95kDa | -0.0313925 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0313497 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0313253 |
| EGR1 | early growth response 1 | -0.030933 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0307343 |
| RRBP1 | ribosome binding protein 1 | -0.0305466 |
| GPC5 | glypican 5 | -0.029974 |
| DSTN | destrin (actin depolymerizing factor) | -0.0299445 |
| TP53 | tumor protein p53 | -0.0289823 |
| REST | RE1-silencing transcription factor | -0.0286683 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0282983 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0279047 |
| ANGPTL4 | angiopoietin-like 4 | -0.0277436 |
| RPL34 | ribosomal protein L34 | -0.027443 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.027432 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0271145 |
| CEP57 | centrosomal protein 57kDa | -0.0271107 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.0269404 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0264464 |
| GPC6 | glypican 6 | -0.0263607 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0263304 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -0.0262853 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0260515 |
| SNX14 | sorting nexin 14 | -0.0259491 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0256893 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0255047 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0254799 |
| WAPL | WAPL cohesin release factor | -0.0250932 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0249241 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0248168 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0247755 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0245018 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0243303 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.0238105 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | -0.0238101 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0237054 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.023648 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0234825 |
| SYNRG | synergin, gamma | -0.0233985 |
| SP100 | SP100 nuclear antigen | -0.0233774 |
| CFDP1 | craniofacial development protein 1 | -0.0233258 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0233111 |
| CANX | calnexin | -0.0231983 |
| RPS21 | ribosomal protein S21 | -0.0231521 |
| IGF2 | insulin-like growth factor 2 | -0.0230871 |
| CREBBP | CREB binding protein | -0.0228036 |
| CAVIN1 | caveolae associated protein 1 | -0.0227447 |
| HLA-C | major histocompatibility complex, class I, C | -0.0227239 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0227007 |
| ARF1 | ADP-ribosylation factor 1 | -0.022411 |
| AHI1 | Abelson helper integration site 1 | -0.0223786 |
| SKIL | SKI-like proto-oncogene | -0.0222252 |
| RPL7A | ribosomal protein L7a | -0.0221967 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | -0.0221088 |
| MRC2 | mannose receptor, C type 2 | -0.0221045 |
| NDRG1 | N-myc downstream regulated 1 | -0.0221004 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0220547 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0220395 |
| MYDGF | myeloid-derived growth factor | -0.0220236 |
| PARK7 | parkinson protein 7 | -0.0219262 |
| S100A9 | S100 calcium binding protein A9 | -0.0219093 |
| PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | -0.021901 |
| ATXN1 | ataxin 1 | -0.0218221 |
| NOP58 | NOP58 ribonucleoprotein | -0.0217555 |
| FAM3C | family with sequence similarity 3, member C | -0.0213301 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.021188 |
| TUBB6 | tubulin, beta 6 class V | -0.0211542 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0210666 |
| RPL27A | ribosomal protein L27a | -0.0208464 |
| CCDC138 | coiled-coil domain containing 138 | -0.0208268 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0208062 |
| CD58 | CD58 molecule | -0.0206767 |
| PURB | purine-rich element binding protein B | -0.020628 |
| LDHA | lactate dehydrogenase A | -0.0206056 |
| NTN4 | netrin 4 | -0.0206002 |
| NEMF | nuclear export mediator factor | -0.0205947 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0205842 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0205226 |
| OSBP | oxysterol binding protein | -0.0204991 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | -0.0204987 |
