| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.140729 |
| FNDC3B | fibronectin type III domain containing 3B | 0.114325 |
| CANX | calnexin | 0.10982 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0992445 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0935346 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0832229 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0788805 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0735672 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0717876 |
| FN1 | fibronectin 1 | 0.0706409 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.063979 |
| AHR | aryl hydrocarbon receptor | 0.0634939 |
| SFTPA2 | surfactant protein A2 | 0.0604446 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.059068 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0571025 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0552485 |
| FAT1 | FAT atypical cadherin 1 | 0.0511787 |
| COPA | coatomer protein complex, subunit alpha | 0.0504358 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.05008 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0498596 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0482787 |
| ETNK1 | ethanolamine kinase 1 | 0.0481492 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0474628 |
| VEGFA | vascular endothelial growth factor A | 0.0474056 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0451805 |
| ASPH | aspartate beta-hydroxylase | 0.0451255 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0443245 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0442276 |
| SUCO | SUN domain containing ossification factor | 0.0437563 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0436743 |
| GPC6 | glypican 6 | 0.0430651 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0427987 |
| PTK2 | protein tyrosine kinase 2 | 0.0426696 |
| GPATCH2L | G patch domain containing 2-like | 0.0423615 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0412737 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0409426 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0408501 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0402755 |
| OGA | O-GlcNAcase | 0.0398464 |
| TXNIP | thioredoxin interacting protein | 0.0396254 |
| CD109 | CD109 molecule | 0.0389655 |
| TPM3 | tropomyosin 3 | 0.0389291 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0385742 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0382855 |
| NDRG1 | N-myc downstream regulated 1 | 0.0380931 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0380046 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0379367 |
| HELZ | helicase with zinc finger | 0.0377671 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0367264 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0366915 |
| CADM1 | cell adhesion molecule 1 | 0.036314 |
| GOLGA4 | golgin A4 | 0.0361753 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0358342 |
| VCL | vinculin | 0.0356839 |
| VMP1 | vacuole membrane protein 1 | 0.0345371 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0342377 |
| STC2 | stanniocalcin 2 | 0.0334271 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0332571 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0332478 |
| PCBP2 | poly(rC) binding protein 2 | 0.0330409 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0327664 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0327303 |
| SMAD3 | SMAD family member 3 | 0.0327249 |
| RBM39 | RNA binding motif protein 39 | 0.0326392 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0326054 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0323049 |
| SEPTIN9 | septin 9 | 0.0319035 |
| NRP1 | neuropilin 1 | 0.0314755 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0312721 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0311143 |
| SVIL | supervillin | 0.0310568 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0310153 |
| RUNX1 | runt-related transcription factor 1 | 0.0308283 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0307324 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0306035 |
| INTS6 | integrator complex subunit 6 | 0.0303398 |
| ATXN1 | ataxin 1 | 0.0302246 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0292763 |
| CTBP2 | C-terminal binding protein 2 | 0.0289061 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0288892 |
| DST | dystonin | 0.0288522 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0287514 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0286246 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0284979 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0281372 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0277836 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0277526 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0276967 |
| IL6ST | interleukin 6 signal transducer | 0.0275512 |
| PRELID2 | PRELI domain containing 2 | 0.0274348 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0273338 |
| RCOR1 | REST corepressor 1 | 0.0270705 |
| PKM | pyruvate kinase, muscle | 0.0267874 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0267473 |
| HDGF | hepatoma-derived growth factor | 0.0266151 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0261275 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0260975 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0260336 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0260004 |
| GOLGB1 | golgin B1 | 0.0259695 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.194548 |
| FTL | ferritin, light polypeptide | -0.095604 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0895333 |
| TMSB10 | thymosin beta 10 | -0.0741212 |
| HLA-B | major histocompatibility complex, class I, B | -0.0712451 |
| RPL35A | ribosomal protein L35a | -0.053766 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.052259 |
| TMSB4X | thymosin beta 4, X-linked | -0.0437431 |
| IER3 | immediate early response 3 | -0.0430205 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0387265 |
| MT2A | metallothionein 2A | -0.0371639 |
| PTMA | prothymosin, alpha | -0.0348559 |
| ACTG1 | actin gamma 1 | -0.0334834 |
| RPL31 | ribosomal protein L31 | -0.0315694 |
| TMEM156 | transmembrane protein 156 | -0.0301362 |
| S100A6 | S100 calcium binding protein A6 | -0.0294917 |
| S100A10 | S100 calcium binding protein A10 | -0.0281892 |
| RPL38 | ribosomal protein L38 | -0.0277339 |
| NRG1 | neuregulin 1 | -0.0268443 |
| RPS8 | ribosomal protein S8 | -0.0233016 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0221921 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0221801 |
| RPL34 | ribosomal protein L34 | -0.0220767 |
| RPS24 | ribosomal protein S24 | -0.0218317 |
| RPLP1 | ribosomal protein, large, P1 | -0.0214198 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0208093 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0200783 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0199706 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0192913 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.019095 |
| RPS21 | ribosomal protein S21 | -0.0187208 |
| HLA-A | major histocompatibility complex, class I, A | -0.0185236 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0179793 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0179361 |
| RPL37A | ribosomal protein L37a | -0.0178781 |
| RPL36A | ribosomal protein L36a | -0.0170303 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0169648 |
| RPS27A | ribosomal protein S27a | -0.0166782 |
| CP | ceruloplasmin (ferroxidase) | -0.0164028 |
| ARF1 | ADP-ribosylation factor 1 | -0.0163869 |
| LAMB3 | laminin, beta 3 | -0.0161968 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0159354 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0155877 |
| JUN | jun proto-oncogene | -0.0155265 |
| MT1X | metallothionein 1X | -0.0154454 |
| TRIM56 | tripartite motif containing 56 | -0.014799 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0146706 |
| GNAS | GNAS complex locus | -0.0146644 |
| RPL36AL | ribosomal protein L36a-like | -0.0146536 |
| UBB | ubiquitin B | -0.0146457 |
| ETV1 | ets variant 1 | -0.0145054 |
| KLHL5 | kelch-like family member 5 | -0.0144796 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0144025 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0143301 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0141373 |
| RPLP2 | ribosomal protein, large, P2 | -0.0139949 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0139551 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0139177 |
| FDPS | farnesyl diphosphate synthase | -0.013685 |
| RPL12 | ribosomal protein L12 | -0.0134766 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0134627 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0134551 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0134334 |
| RPS6 | ribosomal protein S6 | -0.0133914 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0132999 |
| B2M | beta-2-microglobulin | -0.0132907 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0130214 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0130111 |
| XAF1 | XIAP associated factor 1 | -0.0129419 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0128402 |
| CD63 | CD63 molecule | -0.0128352 |
| CTSD | cathepsin D | -0.0125839 |
| RPS28 | ribosomal protein S28 | -0.0125445 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0124606 |
| CAVIN1 | caveolae associated protein 1 | -0.0123418 |
| H3-3B | H3.3 histone B | -0.012341 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0122917 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0122405 |
| RPL32 | ribosomal protein L32 | -0.0122233 |
| SELENOK | selenoprotein K | -0.0122204 |
| H1-0 | H1.0 linker histone | -0.0122003 |
| CTSB | cathepsin B | -0.0121983 |
| RPS29 | ribosomal protein S29 | -0.0121522 |
| TLK1 | tousled-like kinase 1 | -0.0121399 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0121393 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0119823 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0118821 |
| RRBP1 | ribosome binding protein 1 | -0.0118694 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0118027 |
| CSTB | cystatin B (stefin B) | -0.0117542 |
| SEC61G | Sec61 gamma subunit | -0.0117251 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0116943 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0115394 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0114559 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0114442 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0114197 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.011381 |
| RPL26 | ribosomal protein L26 | -0.0113573 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | -0.0113035 |
| RPL36 | ribosomal protein L36 | -0.0112245 |
