| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylprednisolone succinate perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylprednisolone succinate_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.0630453 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0615987 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0565929 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0481482 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0466901 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0461804 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.045477 |
| AFDN | afadin, adherens junction formation factor | 0.0424607 |
| MED13L | mediator complex subunit 13-like | 0.0419101 |
| YAP1 | Yes-associated protein 1 | 0.0416199 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.039974 |
| EZR | ezrin | 0.0398806 |
| TJP1 | tight junction protein 1 | 0.0391136 |
| DSPP | dentin sialophosphoprotein | 0.0374019 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0370028 |
| PLEC | plectin | 0.0359566 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0355312 |
| ANXA2 | annexin A2 | 0.034432 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0336802 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0333015 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0332429 |
| RBM39 | RNA binding motif protein 39 | 0.0330085 |
| ZNF292 | zinc finger protein 292 | 0.032769 |
| NDRG1 | N-myc downstream regulated 1 | 0.0326895 |
| DSCAM | Down syndrome cell adhesion molecule | 0.031803 |
| RPS12 | ribosomal protein S12 | 0.0308218 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0307819 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0307153 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0305127 |
| CTBP2 | C-terminal binding protein 2 | 0.0304235 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0304057 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0292946 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.02896 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0287661 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0281622 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0281491 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0275615 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0273771 |
| PCBP2 | poly(rC) binding protein 2 | 0.0272553 |
| RYBP | RING1 and YY1 binding protein | 0.0271165 |
| CCNL1 | cyclin L1 | 0.0269674 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.026815 |
| CUL3 | cullin 3 | 0.026765 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0266968 |
| ANXA11 | annexin A11 | 0.0265253 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0262744 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0261949 |
| VMP1 | vacuole membrane protein 1 | 0.0261664 |
| NCKAP1 | NCK-associated protein 1 | 0.0259743 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0257404 |
| TUFT1 | tuftelin 1 | 0.0256708 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0256045 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0255038 |
| MYO10 | myosin X | 0.0254757 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0254467 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0254451 |
| GPHN | gephyrin | 0.0251903 |
| SQSTM1 | sequestosome 1 | 0.0246114 |
| BRD2 | bromodomain containing 2 | 0.0240238 |
| ATL2 | atlastin GTPase 2 | 0.0238501 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0237034 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0236771 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0235149 |
| MYO1E | myosin IE | 0.0230112 |
| FLNA | filamin A, alpha | 0.0223759 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0221845 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0216824 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0215081 |
| MYO5B | myosin VB | 0.0214598 |
| ACTN4 | actinin, alpha 4 | 0.0213973 |
| KIAA1671 | KIAA1671 | 0.021374 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0212786 |
| CEP250 | centrosomal protein 250kDa | 0.0212393 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0212353 |
| PGK1 | phosphoglycerate kinase 1 | 0.0209479 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209312 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0207096 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0206676 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.020607 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0204425 |
| NPTN | neuroplastin | 0.0204254 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0203807 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0202622 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0200066 |
| CDYL | chromodomain protein, Y-like | 0.019835 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0198252 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0194699 |
| MAT2A | methionine adenosyltransferase II, alpha | 0.0194389 |
| DIDO1 | death inducer-obliterator 1 | 0.0193183 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.019236 |
| RND3 | Rho family GTPase 3 | 0.0192282 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0191959 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0191889 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0191622 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0191275 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0188853 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0188552 |
| ADM | adrenomedullin | 0.0186028 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0184467 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0184016 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.107982 |
| TMSB10 | thymosin beta 10 | -0.0877153 |
| FTL | ferritin, light polypeptide | -0.0642975 |
| EHBP1 | EH domain binding protein 1 | -0.0557775 |
| KRT18 | keratin 18, type I | -0.0489047 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0466057 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0465988 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0454911 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0377957 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0371084 |
| EPCAM | epithelial cell adhesion molecule | -0.0315836 |
| EGR1 | early growth response 1 | -0.0314561 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0308851 |
| H1-0 | H1.0 linker histone | -0.0297944 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0284564 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0284301 |
| IER3 | immediate early response 3 | -0.0264201 |
| GOLGA4 | golgin A4 | -0.0259804 |
| TMSB4X | thymosin beta 4, X-linked | -0.0256309 |
| UBC | ubiquitin C | -0.0256182 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0248663 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0242405 |
| RPS24 | ribosomal protein S24 | -0.0239492 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0239199 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0231091 |
| RPL32 | ribosomal protein L32 | -0.023063 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0229898 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0229668 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0229218 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0228953 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0228026 |
| KRT8 | keratin 8, type II | -0.0223742 |
| MX2 | MX dynamin-like GTPase 2 | -0.0219228 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.020782 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0206799 |
| S100A6 | S100 calcium binding protein A6 | -0.0203961 |
| RPL18 | ribosomal protein L18 | -0.0198596 |
| RPL35A | ribosomal protein L35a | -0.0196816 |
| CUX1 | cut-like homeobox 1 | -0.0195942 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0193551 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0193239 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.0188678 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0187554 |
| ARF1 | ADP-ribosylation factor 1 | -0.018519 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0182397 |
| MKI67 | marker of proliferation Ki-67 | -0.0181576 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0176385 |
| CD2AP | CD2-associated protein | -0.0175462 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0174341 |
| CBX3 | chromobox homolog 3 | -0.0173538 |
| TMEM41B | transmembrane protein 41B | -0.0172951 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0172789 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.016922 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0169099 |
| TPX2 | TPX2, microtubule-associated | -0.0166971 |
| HMGB2 | high mobility group box 2 | -0.0165302 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0161499 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0160527 |
| LAMA4 | laminin, alpha 4 | -0.0158261 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0156765 |
| RPS21 | ribosomal protein S21 | -0.0155371 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0154799 |
| RPS19 | ribosomal protein S19 | -0.0154772 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0154316 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0153618 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0149473 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0146705 |
| PLSCR1 | phospholipid scramblase 1 | -0.0144895 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0144453 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0143606 |
| HMGB1 | high mobility group box 1 | -0.0143478 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0142163 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0141532 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0137323 |
| SDC4 | syndecan 4 | -0.0137079 |
| CDK12 | cyclin-dependent kinase 12 | -0.0136095 |
| ASTN2 | astrotactin 2 | -0.0135312 |
| KLF10 | Kruppel-like factor 10 | -0.0135051 |
| H3-3B | H3.3 histone B | -0.0134004 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0133611 |
| WAPL | WAPL cohesin release factor | -0.0132278 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0131856 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0131486 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0131462 |
| NF1 | neurofibromin 1 | -0.0131371 |
| TGFA | transforming growth factor, alpha | -0.0131242 |
| CTSD | cathepsin D | -0.0131185 |
| MYOF | myoferlin | -0.0129705 |
| SRRM3 | serine/arginine repetitive matrix 3 | -0.0129379 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0128108 |
| RPL36A | ribosomal protein L36a | -0.0127707 |
| MATR3 | matrin 3 | -0.0127634 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0126895 |
| CCND1 | cyclin D1 | -0.0126059 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0124055 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0123935 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0123392 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | -0.0122258 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0122179 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0121339 |
