| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.12659 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.109968 |
| POTEF | POTE ankyrin domain family, member F | 0.088455 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0839664 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.077309 |
| FBN1 | fibrillin 1 | 0.0726299 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0707238 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0684864 |
| DST | dystonin | 0.0663673 |
| CALR | calreticulin | 0.0632617 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0574655 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.057243 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0568347 |
| GOLGA4 | golgin A4 | 0.0545795 |
| CD44 | CD44 molecule (Indian blood group) | 0.054334 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0502509 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0498033 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0468554 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0464669 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0455023 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0442716 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0432314 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0420539 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0419434 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0410458 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.041039 |
| MYO9A | myosin IXA | 0.0408855 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0408376 |
| NAV2 | neuron navigator 2 | 0.0404174 |
| EGFR | epidermal growth factor receptor | 0.0398865 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0396789 |
| OPTN | optineurin | 0.0393734 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0392579 |
| C1D | C1D nuclear receptor corepressor | 0.039059 |
| PRRC2C | proline-rich coiled-coil 2C | 0.038772 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0379473 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0378292 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0370476 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0368865 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0364412 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0363488 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0361967 |
| ATP13A3 | ATPase type 13A3 | 0.0361861 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0357788 |
| COPA | coatomer protein complex, subunit alpha | 0.0352329 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0349827 |
| OGA | O-GlcNAcase | 0.0345649 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0342028 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0340442 |
| NKTR | natural killer cell triggering receptor | 0.0339175 |
| MX2 | MX dynamin-like GTPase 2 | 0.0338801 |
| HDAC9 | histone deacetylase 9 | 0.0337776 |
| ADAR | adenosine deaminase, RNA-specific | 0.0336962 |
| FOSL1 | FOS-like antigen 1 | 0.0336242 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0330442 |
| ARRDC3 | arrestin domain containing 3 | 0.0328384 |
| MMP12 | matrix metallopeptidase 12 | 0.0324871 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0323054 |
| YEATS2 | YEATS domain containing 2 | 0.0318071 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0314206 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0312991 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.031266 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0311727 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0311136 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0309242 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0297033 |
| SPAG9 | sperm associated antigen 9 | 0.0295835 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0286225 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0286084 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.028585 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0282818 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0278524 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0278164 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0277608 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0272805 |
| CUL4A | cullin 4A | 0.0272539 |
| RNF213 | ring finger protein 213 | 0.0271871 |
| USP34 | ubiquitin specific peptidase 34 | 0.0266792 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 0.0265005 |
| VMP1 | vacuole membrane protein 1 | 0.0263385 |
| SQSTM1 | sequestosome 1 | 0.02631 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0259397 |
| SON | SON DNA binding protein | 0.0258337 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0257545 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0256904 |
| FNBP4 | formin binding protein 4 | 0.0256707 |
| HDLBP | high density lipoprotein binding protein | 0.0255315 |
| RND3 | Rho family GTPase 3 | 0.0255247 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0254435 |
| AXL | AXL receptor tyrosine kinase | 0.0251961 |
| MEF2A | myocyte enhancer factor 2A | 0.0251191 |
| TRIM22 | tripartite motif containing 22 | 0.0249229 |
| ANK2 | ankyrin 2, neuronal | 0.0247846 |
| MSN | moesin | 0.0246066 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0244742 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0242255 |
| KIAA1217 | KIAA1217 | 0.0241691 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0240359 |
| TPM3 | tropomyosin 3 | 0.0239998 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0237295 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.193874 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.149525 |
| CDH13 | cadherin 13 | -0.143752 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.111873 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.101543 |
| MT2A | metallothionein 2A | -0.0871363 |
| PLAT | plasminogen activator, tissue | -0.0861381 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0839838 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0772284 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0735903 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0720927 |
| VIM | vimentin | -0.0689073 |
| COL3A1 | collagen, type III, alpha 1 | -0.0667687 |
| CAVIN1 | caveolae associated protein 1 | -0.0578328 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0527692 |
| SLC39A11 | solute carrier family 39, member 11 | -0.050477 |
| FRMD4A | FERM domain containing 4A | -0.0467614 |
| EFNA5 | ephrin-A5 | -0.0456311 |
| PRSS23 | protease, serine, 23 | -0.0453407 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0426569 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0425377 |
| S100A10 | S100 calcium binding protein A10 | -0.0423916 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0420891 |
| LMNA | lamin A/C | -0.0413571 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.041193 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0411663 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0411472 |
| CUX1 | cut-like homeobox 1 | -0.0387576 |
| TMSB4X | thymosin beta 4, X-linked | -0.0362459 |
| CD99 | CD99 molecule | -0.036088 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0359637 |
| MSI2 | musashi RNA-binding protein 2 | -0.0347983 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0347911 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0347323 |
| CTSB | cathepsin B | -0.0328264 |
| THBS2 | thrombospondin 2 | -0.031559 |
| INTS6 | integrator complex subunit 6 | -0.0311128 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0303122 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0301321 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.02952 |
| MT1X | metallothionein 1X | -0.0278149 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0277062 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.02738 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0270999 |
| NDRG1 | N-myc downstream regulated 1 | -0.0262258 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0261024 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.025768 |
| PTMA | prothymosin, alpha | -0.0255448 |
| APP | amyloid beta (A4) precursor protein | -0.0252902 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0252222 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.0249344 |
| RPL37A | ribosomal protein L37a | -0.0247944 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0245783 |
| FN1 | fibronectin 1 | -0.0243613 |
| ASPH | aspartate beta-hydroxylase | -0.0240072 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0238335 |
| TGFB1 | transforming growth factor, beta 1 | -0.0237118 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0236739 |
| CD59 | CD59 molecule, complement regulatory protein | -0.023376 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0233348 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0222072 |
| LRRC17 | leucine rich repeat containing 17 | -0.0218287 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0217979 |
| ZNF217 | zinc finger protein 217 | -0.0216836 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0215548 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0213041 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0212029 |
| COL1A2 | collagen, type I, alpha 2 | -0.0208431 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.0200485 |
| SUCNR1 | succinate receptor 1 | -0.0200409 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0196075 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | -0.0194174 |
| IPO9 | importin 9 | -0.0193395 |
| TAGLN2 | transgelin 2 | -0.0192845 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0190619 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0190456 |
| CEP170 | centrosomal protein 170kDa | -0.0189452 |
| ACER3 | alkaline ceramidase 3 | -0.0188751 |
| CSTB | cystatin B (stefin B) | -0.0188504 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0187511 |
| RPS3 | ribosomal protein S3 | -0.0187402 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0185058 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0181579 |
| TNS3 | tensin 3 | -0.0181185 |
| HLA-B | major histocompatibility complex, class I, B | -0.0179358 |
| S100A4 | S100 calcium binding protein A4 | -0.0178379 |
| CENPF | centromere protein F, 350/400kDa | -0.0178325 |
| FSTL1 | follistatin-like 1 | -0.0178245 |
| PGK1 | phosphoglycerate kinase 1 | -0.0177563 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0174058 |
| PLXNA2 | plexin A2 | -0.0173023 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0170086 |
| AEBP2 | AE binding protein 2 | -0.0169899 |
| RIGI | RNA sensor RIG-I | -0.0167262 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0165896 |
| RAI14 | retinoic acid induced 14 | -0.0165145 |
| GNAS | GNAS complex locus | -0.0164935 |
| SEC61G | Sec61 gamma subunit | -0.0161716 |
| HOXD10 | homeobox D10 | -0.0160583 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0160265 |
