| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FMN1 | formin 1 | 0.110027 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0571237 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0477348 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0467176 |
| DST | dystonin | 0.0437793 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.043038 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0393268 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.039157 |
| TLE4 | transducin-like enhancer of split 4 | 0.0371655 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0359553 |
| PHIP | pleckstrin homology domain interacting protein | 0.0341209 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0336393 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0334004 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0317241 |
| MED13 | mediator complex subunit 13 | 0.0316303 |
| UBC | ubiquitin C | 0.030249 |
| LPIN1 | lipin 1 | 0.0302092 |
| QKI | QKI, KH domain containing, RNA binding | 0.0300827 |
| CCNL1 | cyclin L1 | 0.0291987 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0290587 |
| CD44 | CD44 molecule (Indian blood group) | 0.0290372 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0289958 |
| HELZ | helicase with zinc finger | 0.0289097 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0285482 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0261789 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261474 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0257553 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0257141 |
| CUL3 | cullin 3 | 0.0253577 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0252896 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0251743 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249496 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.0248001 |
| RAB30 | RAB30, member RAS oncogene family | 0.0247613 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0247364 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0244518 |
| GPC5 | glypican 5 | 0.0243893 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0237459 |
| FOXP1 | forkhead box P1 | 0.0237036 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0235165 |
| ZNF292 | zinc finger protein 292 | 0.0234916 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0234714 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.02314 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0230868 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0228916 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0227722 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0225619 |
| RBM39 | RNA binding motif protein 39 | 0.0225157 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.022368 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.022251 |
| USP34 | ubiquitin specific peptidase 34 | 0.0219775 |
| MYO1B | myosin IB | 0.0218335 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0218313 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0217222 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0216952 |
| PCBP2 | poly(rC) binding protein 2 | 0.0216455 |
| PUM3 | pumilio RNA binding family member 3 | 0.0213831 |
| CDC27 | cell division cycle 27 | 0.0212735 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0212033 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0205232 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0201513 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0200779 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0200591 |
| SLC38A2 | solute carrier family 38, member 2 | 0.020015 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0199956 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0198813 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0198642 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0198289 |
| ACLY | ATP citrate lyase | 0.0195904 |
| MYO9A | myosin IXA | 0.0195722 |
| MORF4L2 | mortality factor 4 like 2 | 0.0195489 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0194525 |
| COPA | coatomer protein complex, subunit alpha | 0.0193432 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0191022 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0190069 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0189686 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0188683 |
| MYO1E | myosin IE | 0.0188452 |
| TCP1 | t-complex 1 | 0.0188293 |
| TXNL1 | thioredoxin-like 1 | 0.0186945 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0186004 |
| LIMA1 | LIM domain and actin binding 1 | 0.0185761 |
| SPPL3 | signal peptide peptidase like 3 | 0.0185651 |
| DPH6 | diphthamine biosynthesis 6 | 0.0183837 |
| TRIB2 | tribbles pseudokinase 2 | 0.018348 |
| GPC6 | glypican 6 | 0.0182784 |
| DTNA | dystrobrevin, alpha | 0.01826 |
| NUP58 | nucleoporin 58 | 0.0181009 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0180478 |
| AUTS2 | autism susceptibility candidate 2 | 0.0180325 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0180049 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0179113 |
| PCNX1 | pecanex 1 | 0.0177586 |
| CDK6 | cyclin-dependent kinase 6 | 0.0176946 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0176499 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0176176 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0175654 |
| CDON | cell adhesion associated, oncogene regulated | 0.0175233 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0174287 |
| FMNL2 | formin-like 2 | 0.0173833 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.206472 |
| NRG1 | neuregulin 1 | -0.126842 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.11193 |
| PTMA | prothymosin, alpha | -0.103831 |
| RPL23 | ribosomal protein L23 | -0.103682 |
| LSAMP | limbic system-associated membrane protein | -0.093908 |
| RPS6 | ribosomal protein S6 | -0.0881489 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0830813 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0805014 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.072499 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0701367 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0648125 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0639522 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0606065 |
| RPL19 | ribosomal protein L19 | -0.0567906 |
| RPL34 | ribosomal protein L34 | -0.0558109 |
| RPS3 | ribosomal protein S3 | -0.0557943 |
| MSI2 | musashi RNA-binding protein 2 | -0.0515337 |
| RPS19 | ribosomal protein S19 | -0.0508847 |
| RPL38 | ribosomal protein L38 | -0.050811 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0502831 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0500407 |
| PLAT | plasminogen activator, tissue | -0.0498601 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0491073 |
| PRKCA | protein kinase C, alpha | -0.0479949 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.046271 |
| TMSB10 | thymosin beta 10 | -0.0453087 |
| RPS27 | ribosomal protein S27 | -0.0444835 |
| RPLP1 | ribosomal protein, large, P1 | -0.0440446 |
| CALR | calreticulin | -0.0426918 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0391331 |
| RPS24 | ribosomal protein S24 | -0.0384511 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0380389 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0375851 |
| NREP | neuronal regeneration related protein | -0.0369397 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0364913 |
| RPL37 | ribosomal protein L37 | -0.03553 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0351088 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0345657 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0344726 |
| RPL37A | ribosomal protein L37a | -0.0340302 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0338402 |
| RPL27 | ribosomal protein L27 | -0.0331247 |
| S100A9 | S100 calcium binding protein A9 | -0.032948 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0329298 |
| FTL | ferritin, light polypeptide | -0.032894 |
| GNAS | GNAS complex locus | -0.0326311 |
| TBX2 | T-box 2 | -0.0323696 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0320704 |
| RPS17 | ribosomal protein S17 | -0.0312692 |
| RPL31 | ribosomal protein L31 | -0.0308227 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0306241 |
| FRMD4A | FERM domain containing 4A | -0.030228 |
| RPS15 | ribosomal protein S15 | -0.0301369 |
| RPL36A | ribosomal protein L36a | -0.0299336 |
| COL1A1 | collagen, type I, alpha 1 | -0.0295424 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0295103 |
| B2M | beta-2-microglobulin | -0.0289283 |
| RPS2 | ribosomal protein S2 | -0.028898 |
| RPL36 | ribosomal protein L36 | -0.028414 |
| RPL35 | ribosomal protein L35 | -0.0279307 |
| SIK2 | salt-inducible kinase 2 | -0.0279041 |
| ACTG1 | actin gamma 1 | -0.0276088 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.027473 |
| RPL35A | ribosomal protein L35a | -0.027131 |
| RPS29 | ribosomal protein S29 | -0.0271109 |
| RGS5 | regulator of G-protein signaling 5 | -0.0270047 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0268788 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0268449 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0267691 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0263608 |
| ACBD6 | acyl-CoA binding domain containing 6 | -0.0258901 |
| CADM2 | cell adhesion molecule 2 | -0.0254171 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0253126 |
| SSH2 | slingshot protein phosphatase 2 | -0.0251614 |
| CUX1 | cut-like homeobox 1 | -0.0251195 |
| RACK1 | receptor for activated C kinase 1 | -0.0248513 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.024814 |
| RPL28 | ribosomal protein L28 | -0.0245913 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0244459 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0243778 |
| RPL12 | ribosomal protein L12 | -0.0243534 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.024013 |
| RPS12 | ribosomal protein S12 | -0.0238266 |
| ZXDC | ZXD family zinc finger C | -0.0237044 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0236791 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | -0.023603 |
| RPS27A | ribosomal protein S27a | -0.0234978 |
| GLG1 | golgi glycoprotein 1 | -0.0234631 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0234385 |
| CADM1 | cell adhesion molecule 1 | -0.023416 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0234013 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0231941 |
| RPL26 | ribosomal protein L26 | -0.0231837 |
| TRIM24 | tripartite motif containing 24 | -0.0230605 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0230296 |
| RPS16 | ribosomal protein S16 | -0.0229798 |
| CRH | corticotropin releasing hormone | -0.022711 |
| RPS14 | ribosomal protein S14 | -0.0226748 |
| VIM | vimentin | -0.0221167 |
