| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.166065 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.163707 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.160593 |
| MTSS1 | metastasis suppressor 1 | 0.160491 |
| LMO7 | LIM domain 7 | 0.146301 |
| FLNB | filamin B, beta | 0.136816 |
| DPYD | dihydropyrimidine dehydrogenase | 0.108625 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.100586 |
| NDRG1 | N-myc downstream regulated 1 | 0.0974032 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0971961 |
| PDLIM5 | PDZ and LIM domain 5 | 0.093045 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0856314 |
| ANXA1 | annexin A1 | 0.0794733 |
| CD44 | CD44 molecule (Indian blood group) | 0.077241 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0750701 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0714815 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0712983 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.07072 |
| PODXL | podocalyxin-like | 0.0694002 |
| RASAL2 | RAS protein activator like 2 | 0.0693057 |
| RAI14 | retinoic acid induced 14 | 0.0672108 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0655197 |
| MYOF | myoferlin | 0.0654656 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0650921 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0643212 |
| SULF1 | sulfatase 1 | 0.0631712 |
| AHNAK | AHNAK nucleoprotein | 0.0626392 |
| PTK2 | protein tyrosine kinase 2 | 0.0624682 |
| JMJD1C | jumonji domain containing 1C | 0.0602822 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0599296 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0584405 |
| EMP1 | epithelial membrane protein 1 | 0.0579644 |
| ITGA6 | integrin, alpha 6 | 0.0574217 |
| MSN | moesin | 0.0572193 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.056833 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0566917 |
| INTS6 | integrator complex subunit 6 | 0.0550492 |
| EFNA5 | ephrin-A5 | 0.0544825 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0539068 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0538261 |
| CDK6 | cyclin-dependent kinase 6 | 0.05277 |
| GRB10 | growth factor receptor-bound protein 10 | 0.052686 |
| FN1 | fibronectin 1 | 0.0519668 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0517537 |
| LDHA | lactate dehydrogenase A | 0.0516441 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0508288 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0504185 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0499859 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0499261 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.049162 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0488885 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0484024 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0482311 |
| ANXA2 | annexin A2 | 0.0480848 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0477301 |
| RBM39 | RNA binding motif protein 39 | 0.0475781 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0460478 |
| MECOM | MDS1 and EVI1 complex locus | 0.0446059 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0439991 |
| FNIP1 | folliculin interacting protein 1 | 0.0438534 |
| MEF2A | myocyte enhancer factor 2A | 0.0432123 |
| ASPH | aspartate beta-hydroxylase | 0.042762 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0423342 |
| NAV2 | neuron navigator 2 | 0.0418027 |
| DST | dystonin | 0.0409894 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0409327 |
| PALLD | palladin, cytoskeletal associated protein | 0.040919 |
| RCOR1 | REST corepressor 1 | 0.0406765 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0403212 |
| PRELID2 | PRELI domain containing 2 | 0.0396335 |
| SULF2 | sulfatase 2 | 0.0385808 |
| TNS3 | tensin 3 | 0.0385223 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0384004 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.038026 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0379771 |
| PLS3 | plastin 3 | 0.0376562 |
| UTRN | utrophin | 0.0373424 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0371994 |
| GOLGB1 | golgin B1 | 0.037152 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0370377 |
| DOK5 | docking protein 5 | 0.0369641 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0362786 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0362757 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0361672 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0353011 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0352708 |
| DIAPH1 | diaphanous-related formin 1 | 0.035264 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0347756 |
| TXNIP | thioredoxin interacting protein | 0.0346487 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0345416 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0345239 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0343711 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0343322 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0343078 |
| CALB1 | calbindin 1, 28kDa | 0.0341437 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0341082 |
| AMOTL1 | angiomotin like 1 | 0.0339657 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0338112 |
| BLCAP | bladder cancer associated protein | 0.0336205 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0334428 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.11812 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0738831 |
| MT2A | metallothionein 2A | -0.068642 |
| PTMA | prothymosin, alpha | -0.0668272 |
| RPS21 | ribosomal protein S21 | -0.0548657 |
| RPS19 | ribosomal protein S19 | -0.0495521 |
| RPS6 | ribosomal protein S6 | -0.0426726 |
| RPS3 | ribosomal protein S3 | -0.039555 |
| S100A9 | S100 calcium binding protein A9 | -0.0384806 |
| RPLP2 | ribosomal protein, large, P2 | -0.0384211 |
| RPLP1 | ribosomal protein, large, P1 | -0.0381122 |
| RPL36 | ribosomal protein L36 | -0.0326845 |
| S100A2 | S100 calcium binding protein A2 | -0.0319345 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0315533 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0314405 |
| RPS8 | ribosomal protein S8 | -0.0310425 |
| BCL2L1 | BCL2-like 1 | -0.0308448 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0306975 |
| S100A10 | S100 calcium binding protein A10 | -0.0300465 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0298053 |
| RPL23 | ribosomal protein L23 | -0.0292817 |
| RPL8 | ribosomal protein L8 | -0.0292308 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0286012 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0283361 |
| S100A6 | S100 calcium binding protein A6 | -0.0283093 |
| KRT17 | keratin 17, type I | -0.0278036 |
| RPL11 | ribosomal protein L11 | -0.0270506 |
| RPL28 | ribosomal protein L28 | -0.0269121 |
| LMNA | lamin A/C | -0.0264102 |
| MT1X | metallothionein 1X | -0.0254188 |
| RPL35A | ribosomal protein L35a | -0.0247786 |
| FTL | ferritin, light polypeptide | -0.0247036 |
| RPL35 | ribosomal protein L35 | -0.0243976 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0243543 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.024348 |
| FOSL1 | FOS-like antigen 1 | -0.0236914 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0220387 |
| RPL37A | ribosomal protein L37a | -0.021859 |
| RPS27 | ribosomal protein S27 | -0.021646 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0215475 |
| RPS14 | ribosomal protein S14 | -0.0213492 |
| RPL19 | ribosomal protein L19 | -0.0212401 |
| RPS2 | ribosomal protein S2 | -0.0211672 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0211157 |
| RPL34 | ribosomal protein L34 | -0.0209909 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0208306 |
| RPS27A | ribosomal protein S27a | -0.0201539 |
| RPL31 | ribosomal protein L31 | -0.0199362 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0192676 |
| RPS29 | ribosomal protein S29 | -0.019226 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0188721 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0188719 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.018198 |
| S100A11 | S100 calcium binding protein A11 | -0.0180717 |
| CAVIN1 | caveolae associated protein 1 | -0.0180013 |
| SEC61G | Sec61 gamma subunit | -0.0179229 |
| CD99 | CD99 molecule | -0.0178753 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0177494 |
| RPS12 | ribosomal protein S12 | -0.0176066 |
| RPS13 | ribosomal protein S13 | -0.0175951 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0175144 |
| RPL27A | ribosomal protein L27a | -0.0174225 |
| RPL18 | ribosomal protein L18 | -0.0174069 |
| RPL32 | ribosomal protein L32 | -0.0173326 |
| RPL12 | ribosomal protein L12 | -0.0171229 |
| RPS11 | ribosomal protein S11 | -0.0167849 |
| DUSP6 | dual specificity phosphatase 6 | -0.0166203 |
| ROMO1 | reactive oxygen species modulator 1 | -0.0164667 |
| RPL26 | ribosomal protein L26 | -0.0163365 |
| PFN1 | profilin 1 | -0.0159784 |
| S100A4 | S100 calcium binding protein A4 | -0.0156732 |
| CST3 | cystatin C | -0.0155883 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0155684 |
| RPL38 | ribosomal protein L38 | -0.0154594 |
| GUK1 | guanylate kinase 1 | -0.0154106 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0153809 |
| RPS20 | ribosomal protein S20 | -0.015294 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0152066 |
| RACK1 | receptor for activated C kinase 1 | -0.0151941 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0150795 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.0148275 |
| IER3 | immediate early response 3 | -0.014703 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -0.014697 |
| SERF2 | small EDRK-rich factor 2 | -0.0146685 |
| RPS25 | ribosomal protein S25 | -0.0145607 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0144633 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0143536 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0142989 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0141589 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0141468 |
| GOLGA4 | golgin A4 | -0.0141445 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | -0.0141402 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0141387 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.0140838 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0139986 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0139828 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0139788 |
| RPL37 | ribosomal protein L37 | -0.0138804 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0138051 |
| RPL7A | ribosomal protein L7a | -0.0137365 |
