| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.459062 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.116458 |
| EMP1 | epithelial membrane protein 1 | 0.109992 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.100465 |
| LMO7 | LIM domain 7 | 0.0945669 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0921967 |
| KRT8 | keratin 8, type II | 0.0826667 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0749764 |
| NPSR1 | neuropeptide S receptor 1 | 0.0745383 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0725209 |
| KRT18 | keratin 18, type I | 0.0680797 |
| FAT1 | FAT atypical cadherin 1 | 0.0674929 |
| EZR | ezrin | 0.066515 |
| ANXA2 | annexin A2 | 0.0638732 |
| FLNB | filamin B, beta | 0.0627481 |
| ITGA6 | integrin, alpha 6 | 0.0569887 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.056242 |
| ANXA1 | annexin A1 | 0.0548326 |
| EHBP1 | EH domain binding protein 1 | 0.054648 |
| B2M | beta-2-microglobulin | 0.0516209 |
| RNF213 | ring finger protein 213 | 0.0503461 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0488263 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0458487 |
| CALR | calreticulin | 0.0440453 |
| CDK6 | cyclin-dependent kinase 6 | 0.0439021 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0438449 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0431343 |
| AHR | aryl hydrocarbon receptor | 0.0429797 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0429767 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0424264 |
| TNIK | TRAF2 and NCK interacting kinase | 0.040248 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0400126 |
| ASPH | aspartate beta-hydroxylase | 0.0399873 |
| ATXN1 | ataxin 1 | 0.0395938 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0390836 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0388864 |
| POTEF | POTE ankyrin domain family, member F | 0.0387269 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | 0.0386746 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0385952 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0359667 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0358648 |
| PGK1 | phosphoglycerate kinase 1 | 0.0358632 |
| VMP1 | vacuole membrane protein 1 | 0.0357699 |
| POF1B | premature ovarian failure, 1B | 0.0350341 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0348847 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0341905 |
| SIK3 | SIK family kinase 3 | 0.0318634 |
| MYOF | myoferlin | 0.0310704 |
| MCU | mitochondrial calcium uniporter | 0.0304064 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0303429 |
| BCL2L1 | BCL2-like 1 | 0.0300058 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.029442 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0291829 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0287188 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0286633 |
| TMC5 | transmembrane channel-like 5 | 0.0284451 |
| TJP1 | tight junction protein 1 | 0.0283598 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0280205 |
| RUNX1 | runt-related transcription factor 1 | 0.0279521 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0278652 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0278157 |
| MYO1E | myosin IE | 0.027804 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0275597 |
| FRMD5 | FERM domain containing 5 | 0.0274795 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0274326 |
| COBL | cordon-bleu WH2 repeat protein | 0.0272814 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0268091 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0267846 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0258566 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0257486 |
| DSPP | dentin sialophosphoprotein | 0.02564 |
| TMSB4X | thymosin beta 4, X-linked | 0.0254689 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0252311 |
| EXOC4 | exocyst complex component 4 | 0.0249747 |
| DSG2 | desmoglein 2 | 0.0249456 |
| GOLGB1 | golgin B1 | 0.0249288 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0247734 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0245663 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0245527 |
| CUX1 | cut-like homeobox 1 | 0.0245363 |
| DSTN | destrin (actin depolymerizing factor) | 0.0243167 |
| TCF12 | transcription factor 12 | 0.0242424 |
| CMIP | c-Maf inducing protein | 0.0240386 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0239248 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0234299 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.023132 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0230233 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0228566 |
| ACTG1 | actin gamma 1 | 0.0228135 |
| PRKCA | protein kinase C, alpha | 0.0227807 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0227577 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0225685 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0224008 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0223777 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0221251 |
| PLEC | plectin | 0.0220536 |
| YAP1 | Yes-associated protein 1 | 0.0215899 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0215772 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0214816 |
| MSI2 | musashi RNA-binding protein 2 | 0.0214286 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0584357 |
| RPL35A | ribosomal protein L35a | -0.0362013 |
| RPL23 | ribosomal protein L23 | -0.0247372 |
| AGR2 | anterior gradient 2 | -0.0243753 |
| RPLP1 | ribosomal protein, large, P1 | -0.0239569 |
| FTL | ferritin, light polypeptide | -0.0237572 |
| RPS19 | ribosomal protein S19 | -0.0198808 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0193009 |
| S100A9 | S100 calcium binding protein A9 | -0.0186003 |
| RPS6 | ribosomal protein S6 | -0.0184072 |
| HMGA1 | high mobility group AT-hook 1 | -0.0159309 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0137455 |
| RPL34 | ribosomal protein L34 | -0.0136213 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0136112 |
| S100P | S100 calcium binding protein P | -0.0135948 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0128828 |
| SEC61G | Sec61 gamma subunit | -0.0128801 |
| RPS29 | ribosomal protein S29 | -0.0124626 |
| HMGB1 | high mobility group box 1 | -0.0118958 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0117529 |
| RPL35 | ribosomal protein L35 | -0.0117144 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0116923 |
| RPL28 | ribosomal protein L28 | -0.0113216 |
| RPS27 | ribosomal protein S27 | -0.0110932 |
| PFN1 | profilin 1 | -0.0108625 |
| RPL18 | ribosomal protein L18 | -0.0105578 |
| RPL8 | ribosomal protein L8 | -0.0104076 |
| LOC112694756 | uncharaterized LOC112694756 | -0.00999195 |
| RPL38 | ribosomal protein L38 | -0.00996983 |
| RPS21 | ribosomal protein S21 | -0.00977578 |
| RPL36 | ribosomal protein L36 | -0.00968077 |
| RRBP1 | ribosome binding protein 1 | -0.00960633 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.00940718 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.00909215 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0090019 |
| RPL12 | ribosomal protein L12 | -0.00894554 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.00889846 |
| GSTP1 | glutathione S-transferase pi 1 | -0.00884772 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00879373 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00846171 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.00834116 |
| KLHL24 | kelch-like family member 24 | -0.00830433 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.00828658 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.00822167 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.00812542 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00803986 |
| RPS20 | ribosomal protein S20 | -0.00792764 |
| RPLP2 | ribosomal protein, large, P2 | -0.00791035 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.00777091 |
| UFM1 | ubiquitin-fold modifier 1 | -0.00776585 |
| ATP5MG | ATP synthase membrane subunit g | -0.00771866 |
| SELENOK | selenoprotein K | -0.0077183 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00746476 |
| RPL26 | ribosomal protein L26 | -0.00742563 |
| RPS14 | ribosomal protein S14 | -0.00737565 |
| FAM162A | family with sequence similarity 162, member A | -0.00733666 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.00723817 |
| RPL9 | ribosomal protein L9 | -0.00718642 |
| SPCS2 | signal peptidase complex subunit 2 homolog (S. cerevisiae) | -0.00716839 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.00716439 |
| RPL31 | ribosomal protein L31 | -0.00712204 |
| RPL37A | ribosomal protein L37a | -0.00710299 |
| UFL1 | UFM1-specific ligase 1 | -0.00707384 |
| RPL19 | ribosomal protein L19 | -0.00701334 |
| PRSS3 | protease, serine, 3 | -0.00682904 |
| AFTPH | aftiphilin | -0.00681477 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00679034 |
| VIM | vimentin | -0.0067343 |
| ROMO1 | reactive oxygen species modulator 1 | -0.00668696 |
| ATP5MK | ATP synthase membrane subunit k | -0.00662967 |
| SEPTIN7 | septin 7 | -0.00657714 |
| RPL36AL | ribosomal protein L36a-like | -0.00656575 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00652814 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.00651962 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.00649294 |
| SELENOS | selenoprotein S | -0.00649284 |
| RPL11 | ribosomal protein L11 | -0.00648741 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00646421 |
| RPS27A | ribosomal protein S27a | -0.00646214 |
| MYL12B | myosin, light chain 12B, regulatory | -0.00641762 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | -0.00625226 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.00624044 |
| RPS25 | ribosomal protein S25 | -0.00617886 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00598266 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.00594686 |
| CST3 | cystatin C | -0.00590787 |
| RPS17 | ribosomal protein S17 | -0.0058833 |
| KLHL20 | kelch-like family member 20 | -0.00586638 |
| RPS15 | ribosomal protein S15 | -0.00585065 |
| GGNBP2 | gametogenetin binding protein 2 | -0.00583424 |
| HMGXB4 | HMG box domain containing 4 | -0.00576957 |
| NOL7 | nucleolar protein 7, 27kDa | -0.00570993 |
| GUK1 | guanylate kinase 1 | -0.00569052 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.00557432 |
| COX6C | cytochrome c oxidase subunit VIc | -0.00555707 |
| SSR4 | signal sequence receptor, delta | -0.00553888 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | -0.00548517 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00548279 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00538962 |
| RPS27L | ribosomal protein S27-like | -0.00534612 |
