| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Methylthiouracil_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA6 | integrin, alpha 6 | 0.163307 |
| TXNIP | thioredoxin interacting protein | 0.150497 |
| KRT8 | keratin 8, type II | 0.14657 |
| EZR | ezrin | 0.13934 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.136908 |
| FAT1 | FAT atypical cadherin 1 | 0.123538 |
| VEGFA | vascular endothelial growth factor A | 0.102881 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.10208 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0954477 |
| NDRG1 | N-myc downstream regulated 1 | 0.0899149 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.089591 |
| ANXA1 | annexin A1 | 0.0810431 |
| ASPH | aspartate beta-hydroxylase | 0.0806217 |
| POTEF | POTE ankyrin domain family, member F | 0.0763383 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0748402 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0746265 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0746074 |
| ANXA2 | annexin A2 | 0.0735297 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0693812 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0692989 |
| KRT18 | keratin 18, type I | 0.0676436 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0660813 |
| LDHA | lactate dehydrogenase A | 0.064895 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.064443 |
| FLNB | filamin B, beta | 0.0627448 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.058518 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0563921 |
| B2M | beta-2-microglobulin | 0.0552101 |
| LAMA4 | laminin, alpha 4 | 0.0549888 |
| DSPP | dentin sialophosphoprotein | 0.0548835 |
| PKM | pyruvate kinase, muscle | 0.0542664 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0531179 |
| CALR | calreticulin | 0.0523897 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0522202 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0511902 |
| TPM3 | tropomyosin 3 | 0.0498278 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0497288 |
| EMP1 | epithelial membrane protein 1 | 0.0496641 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0495897 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0488172 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0486839 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0481902 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0470274 |
| CCNY | cyclin Y | 0.045779 |
| ENO1 | enolase 1, (alpha) | 0.0450408 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0434462 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0426063 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0417357 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0412954 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0411586 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0411297 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0408087 |
| LMO7 | LIM domain 7 | 0.0405754 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0400616 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0399089 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0398181 |
| RCOR1 | REST corepressor 1 | 0.0397122 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0389765 |
| BRD2 | bromodomain containing 2 | 0.0389475 |
| MED13L | mediator complex subunit 13-like | 0.0388706 |
| VMP1 | vacuole membrane protein 1 | 0.0384907 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0382262 |
| DSTN | destrin (actin depolymerizing factor) | 0.0381767 |
| MYO5B | myosin VB | 0.0367104 |
| SETD5 | SET domain containing 5 | 0.0363477 |
| TES | testin LIM domain protein | 0.035927 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0355104 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0352124 |
| MCL1 | myeloid cell leukemia 1 | 0.0351585 |
| ANXA11 | annexin A11 | 0.0346016 |
| VCL | vinculin | 0.0341888 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0338136 |
| PGK1 | phosphoglycerate kinase 1 | 0.0335781 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0333049 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0327579 |
| ATXN1 | ataxin 1 | 0.0326842 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0322475 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0322458 |
| EPHA2 | EPH receptor A2 | 0.0321648 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.032129 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.031879 |
| JUN | jun proto-oncogene | 0.0317538 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0317525 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0316591 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0314607 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0313999 |
| ABHD2 | abhydrolase domain containing 2 | 0.0313123 |
| EREG | epiregulin | 0.0313045 |
| TRIM2 | tripartite motif containing 2 | 0.0311234 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0310303 |
| EHF | ets homologous factor | 0.0309858 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0306353 |
| MUC13 | mucin 13, cell surface associated | 0.0305126 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0305037 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0301386 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.030128 |
| HELZ | helicase with zinc finger | 0.0300444 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0298153 |
| MLEC | malectin | 0.0297757 |
| SIK3 | SIK family kinase 3 | 0.0297674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.127882 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0810592 |
| RPLP1 | ribosomal protein, large, P1 | -0.0605485 |
| RPL35A | ribosomal protein L35a | -0.0551442 |
| PRSS3 | protease, serine, 3 | -0.0480164 |
| RNF43 | ring finger protein 43 | -0.048008 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0477165 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0473464 |
| NPSR1 | neuropeptide S receptor 1 | -0.0461647 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0448922 |
| RRBP1 | ribosome binding protein 1 | -0.0435183 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.035059 |
| RPL34 | ribosomal protein L34 | -0.0330492 |
| RPS6 | ribosomal protein S6 | -0.0328453 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0323263 |
| HMGB1 | high mobility group box 1 | -0.0307528 |
| RPS24 | ribosomal protein S24 | -0.0303425 |
| RPL23 | ribosomal protein L23 | -0.0280701 |
| TMEM45B | transmembrane protein 45B | -0.0279878 |
| RPLP2 | ribosomal protein, large, P2 | -0.0278249 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.026397 |
| RPL9 | ribosomal protein L9 | -0.0260654 |
| ONECUT3 | one cut homeobox 3 | -0.025348 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0245179 |
| RPL26 | ribosomal protein L26 | -0.0239587 |
| AGR2 | anterior gradient 2 | -0.0238821 |
| CCND1 | cyclin D1 | -0.0236412 |
| OGA | O-GlcNAcase | -0.0233367 |
| RPL38 | ribosomal protein L38 | -0.0230534 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0218654 |
| NF1 | neurofibromin 1 | -0.0216086 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0210356 |
| RPL12 | ribosomal protein L12 | -0.0209146 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0203523 |
| IER3 | immediate early response 3 | -0.0202225 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0199271 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0198734 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0196485 |
| ZNF33A | zinc finger protein 33A | -0.0196481 |
| RPL4 | ribosomal protein L4 | -0.0194637 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0193541 |
| TSPAN8 | tetraspanin 8 | -0.0192035 |
| RPS27A | ribosomal protein S27a | -0.0188702 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0186293 |
| RBM25 | RNA binding motif protein 25 | -0.0184537 |
| ARF1 | ADP-ribosylation factor 1 | -0.018317 |
| NFX1 | nuclear transcription factor, X-box binding 1 | -0.0182463 |
| RPL27 | ribosomal protein L27 | -0.0182421 |
| RPL19 | ribosomal protein L19 | -0.0181251 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0177474 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0174909 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.0174481 |
| RPS21 | ribosomal protein S21 | -0.0172825 |
| POF1B | premature ovarian failure, 1B | -0.0171701 |
| CAB39 | calcium binding protein 39 | -0.017161 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0169755 |
| XPC | xeroderma pigmentosum, complementation group C | -0.0168441 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0168372 |
| METTL15 | methyltransferase like 15 | -0.0166113 |
| MT2A | metallothionein 2A | -0.0165458 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0163465 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.01634 |
| RANBP17 | RAN binding protein 17 | -0.0163011 |
| RPS19 | ribosomal protein S19 | -0.0162874 |
| FBXO34 | F-box protein 34 | -0.0161077 |
| RPL35 | ribosomal protein L35 | -0.0158162 |
| ABLIM1 | actin binding LIM protein 1 | -0.0158093 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0157662 |
| PHF3 | PHD finger protein 3 | -0.0157161 |
| RPL30 | ribosomal protein L30 | -0.0157122 |
| TNS4 | tensin 4 | -0.0154278 |
| GNAS | GNAS complex locus | -0.0153098 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0150722 |
| NOSTRIN | nitric oxide synthase trafficking | -0.0150523 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0148908 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0148856 |
| NFIA | nuclear factor I/A | -0.0147822 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.014723 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0146759 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0145125 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0144073 |
| PCNX2 | pecanex 2 | -0.014381 |
| ITGB4 | integrin, beta 4 | -0.0142549 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0142422 |
| CD44 | CD44 molecule (Indian blood group) | -0.014158 |
| RAD51B | RAD51 paralog B | -0.0139267 |
| AHNAK | AHNAK nucleoprotein | -0.0139221 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.0139114 |
| RPS20 | ribosomal protein S20 | -0.0138577 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.013836 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0137857 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.0136198 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0135414 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0135396 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0134788 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0134402 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0133991 |
| SMYD3 | SET and MYND domain containing 3 | -0.0133914 |
| HMGB2 | high mobility group box 2 | -0.0133825 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) | -0.0133786 |
