| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.177315 |
| DST | dystonin | 0.132565 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.103868 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.101102 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0969351 |
| FMNL2 | formin-like 2 | 0.0901303 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0898855 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.086347 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0774666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0761698 |
| CD44 | CD44 molecule (Indian blood group) | 0.0743171 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0686675 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0666983 |
| TXNIP | thioredoxin interacting protein | 0.0661065 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0651199 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.062423 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0618202 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0611121 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0600094 |
| MYOF | myoferlin | 0.0595978 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0555984 |
| EFNA5 | ephrin-A5 | 0.055389 |
| CADM2 | cell adhesion molecule 2 | 0.0552329 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0548107 |
| TMSB4X | thymosin beta 4, X-linked | 0.0547718 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0544909 |
| ENO1 | enolase 1, (alpha) | 0.0534431 |
| TNS3 | tensin 3 | 0.0528302 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0514725 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0510283 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0505811 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0497498 |
| FNIP1 | folliculin interacting protein 1 | 0.0477138 |
| PTMA | prothymosin, alpha | 0.0475663 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0473654 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0471629 |
| RNF213 | ring finger protein 213 | 0.0470652 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0468615 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0461755 |
| PRELID2 | PRELI domain containing 2 | 0.0460757 |
| PGK1 | phosphoglycerate kinase 1 | 0.0460481 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0456005 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0448996 |
| B2M | beta-2-microglobulin | 0.0434739 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0432652 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0430478 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0428556 |
| EPHA4 | EPH receptor A4 | 0.0426538 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0424132 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0422876 |
| ANXA1 | annexin A1 | 0.0422638 |
| ZNF292 | zinc finger protein 292 | 0.0417821 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0417327 |
| PLK2 | polo-like kinase 2 | 0.0413995 |
| SLK | STE20-like kinase | 0.0413771 |
| HDAC9 | histone deacetylase 9 | 0.0413485 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0410612 |
| PKM | pyruvate kinase, muscle | 0.0405599 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.04055 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0403223 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0401909 |
| HELZ | helicase with zinc finger | 0.0399986 |
| CALR | calreticulin | 0.0399106 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0396592 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0396207 |
| SPAG9 | sperm associated antigen 9 | 0.0395142 |
| NDRG1 | N-myc downstream regulated 1 | 0.0394278 |
| HLA-B | major histocompatibility complex, class I, B | 0.0392363 |
| APP | amyloid beta (A4) precursor protein | 0.0390306 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0379979 |
| EZR | ezrin | 0.0377481 |
| PODXL | podocalyxin-like | 0.0375881 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0372607 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0370035 |
| GLG1 | golgi glycoprotein 1 | 0.0365173 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0361941 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0357473 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0352699 |
| YEATS2 | YEATS domain containing 2 | 0.0345467 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0344563 |
| LYST | lysosomal trafficking regulator | 0.0335577 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0332742 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0331179 |
| TPM3 | tropomyosin 3 | 0.0329929 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0328086 |
| CCNL1 | cyclin L1 | 0.0327647 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0327455 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0326892 |
| GOLGA4 | golgin A4 | 0.0324017 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0323922 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0323418 |
| HLA-A | major histocompatibility complex, class I, A | 0.0317499 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0313718 |
| ATXN2 | ataxin 2 | 0.0312462 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0307522 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0306158 |
| PDE8A | phosphodiesterase 8A | 0.030604 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0304455 |
| PLIN2 | perilipin 2 | 0.0303226 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0301646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.107608 |
| TMSB10 | thymosin beta 10 | -0.0801811 |
| MT2A | metallothionein 2A | -0.0787459 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0688849 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0625245 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0480378 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.046584 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0455032 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0451768 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0442529 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0440841 |
| MT1X | metallothionein 1X | -0.0402622 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.039012 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0376547 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0333052 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.032201 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0314035 |
| TMEM41B | transmembrane protein 41B | -0.0299699 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0294078 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0288114 |
| RIGI | RNA sensor RIG-I | -0.0280578 |
| RPL23 | ribosomal protein L23 | -0.0280393 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0278044 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0274151 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0271179 |
| DNTTIP1 | deoxynucleotidyltransferase, terminal, interacting protein 1 | -0.0271179 |
| BMERB1 | bMERB domain containing 1 | -0.0268948 |
| ACTG1 | actin gamma 1 | -0.0266873 |
| RGS4 | regulator of G-protein signaling 4 | -0.0264776 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0253358 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0235848 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0235239 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.0219162 |
| EMP1 | epithelial membrane protein 1 | -0.0209243 |
| EGR1 | early growth response 1 | -0.020729 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0206975 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0204621 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.019829 |
| VCL | vinculin | -0.0197138 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0197096 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0197066 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0195493 |
| PLSCR1 | phospholipid scramblase 1 | -0.0195373 |
| OSMR | oncostatin M receptor | -0.0195108 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0192246 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.019139 |
| HPCAL1 | hippocalcin-like 1 | -0.0189503 |
| AHNAK | AHNAK nucleoprotein | -0.018873 |
| ARF1 | ADP-ribosylation factor 1 | -0.0186622 |
| NEK10 | NIMA-related kinase 10 | -0.018236 |
| CDCP1 | CUB domain containing protein 1 | -0.0175994 |
| FERMT1 | fermitin family member 1 | -0.0173241 |
| ERBIN | erbb2 interacting protein | -0.0173027 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0172143 |
| RPLP1 | ribosomal protein, large, P1 | -0.0169254 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | -0.0168964 |
| FHL2 | four and a half LIM domains 2 | -0.0167153 |
| FBXO11 | F-box protein 11 | -0.0165184 |
| TRIM38 | tripartite motif containing 38 | -0.0164931 |
| SGO2 | shugoshin 2 | -0.016025 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0159152 |
| KIF14 | kinesin family member 14 | -0.015596 |
| RPL4 | ribosomal protein L4 | -0.0153911 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0152129 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0150056 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0145413 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0142293 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0140574 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0139298 |
| RASAL2 | RAS protein activator like 2 | -0.0139137 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0138402 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | -0.0138025 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -0.013775 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0136904 |
| TNPO1 | transportin 1 | -0.0135425 |
| RRBP1 | ribosome binding protein 1 | -0.0134917 |
| PMP22 | peripheral myelin protein 22 | -0.0134241 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0134205 |
| IL6ST | interleukin 6 signal transducer | -0.0133805 |
| USP12 | ubiquitin specific peptidase 12 | -0.013314 |
| PDE10A | phosphodiesterase 10A | -0.013241 |
| HDX | highly divergent homeobox | -0.0131789 |
| HMGB1 | high mobility group box 1 | -0.013087 |
| GPATCH8 | G patch domain containing 8 | -0.0130187 |
| CCDC190 | coiled-coil domain containing 190 | -0.0129138 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.012882 |
| RPL35A | ribosomal protein L35a | -0.0128466 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0128374 |
| FAF2 | Fas associated factor family member 2 | -0.0127509 |
| CUL1 | cullin 1 | -0.0126772 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0126456 |
| CENPF | centromere protein F, 350/400kDa | -0.0126363 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.012534 |
| YBX3 | Y box binding protein 3 | -0.0125037 |
| CENPE | centromere protein E, 312kDa | -0.0123424 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0122961 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | -0.0122315 |
| ETV5 | ets variant 5 | -0.0121307 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0121231 |
| KIF18B | kinesin family member 18B | -0.0119716 |
