| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0905373 |
| VIM | vimentin | 0.089076 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0862198 |
| NDRG1 | N-myc downstream regulated 1 | 0.0842027 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0823601 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0699125 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0697357 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0673171 |
| FLNB | filamin B, beta | 0.0625072 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.061769 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0608878 |
| SBF2 | SET binding factor 2 | 0.0584622 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0544491 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0538694 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0534883 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0532146 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0532022 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0530868 |
| NAV2 | neuron navigator 2 | 0.0526665 |
| COPA | coatomer protein complex, subunit alpha | 0.0510287 |
| FAM13A | family with sequence similarity 13, member A | 0.0485075 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0468246 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.046105 |
| PDE10A | phosphodiesterase 10A | 0.0457155 |
| LDHA | lactate dehydrogenase A | 0.0450989 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0429889 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0409523 |
| CANX | calnexin | 0.0401476 |
| EZR | ezrin | 0.0398146 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.039512 |
| MSI2 | musashi RNA-binding protein 2 | 0.0394864 |
| TPM3 | tropomyosin 3 | 0.039474 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0384177 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.037961 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0377959 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0373767 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0367971 |
| GPHN | gephyrin | 0.0367134 |
| PTMA | prothymosin, alpha | 0.0358013 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0354758 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0346126 |
| SLTM | SAFB-like, transcription modulator | 0.0344624 |
| GLG1 | golgi glycoprotein 1 | 0.0338569 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0333166 |
| NF1 | neurofibromin 1 | 0.033282 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0331473 |
| CALU | calumenin | 0.0329804 |
| MYOF | myoferlin | 0.0328748 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0326655 |
| PGK1 | phosphoglycerate kinase 1 | 0.0321174 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0321141 |
| GOLGA2 | golgin A2 | 0.0319216 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0319053 |
| ATXN1 | ataxin 1 | 0.0312186 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0311026 |
| STC1 | stanniocalcin 1 | 0.0309861 |
| RPS3 | ribosomal protein S3 | 0.0309305 |
| RPL37A | ribosomal protein L37a | 0.030902 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0306343 |
| FRMD5 | FERM domain containing 5 | 0.030586 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0305518 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0304841 |
| ACTG1 | actin gamma 1 | 0.0304594 |
| GOLGA4 | golgin A4 | 0.030304 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.029356 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0292079 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0288118 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0287046 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0284121 |
| SMAD3 | SMAD family member 3 | 0.0281313 |
| PAPOLA | poly(A) polymerase alpha | 0.0280819 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0280441 |
| ARRDC3 | arrestin domain containing 3 | 0.0278596 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0275942 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0274241 |
| RBM39 | RNA binding motif protein 39 | 0.0273135 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0272817 |
| CALR | calreticulin | 0.0270514 |
| POTEF | POTE ankyrin domain family, member F | 0.0268147 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0266778 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0265248 |
| MED13L | mediator complex subunit 13-like | 0.0265119 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0264741 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0264024 |
| NOP58 | NOP58 ribonucleoprotein | 0.0263352 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0262649 |
| ZNF292 | zinc finger protein 292 | 0.0260047 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0259752 |
| PTGES2 | prostaglandin E synthase 2 | 0.0257238 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0256055 |
| BRD2 | bromodomain containing 2 | 0.0255834 |
| RPS19 | ribosomal protein S19 | 0.0254677 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0253951 |
| RPS20 | ribosomal protein S20 | 0.0252604 |
| MORF4L1 | mortality factor 4 like 1 | 0.0249863 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0247999 |
| RBM26 | RNA binding motif protein 26 | 0.024478 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0243212 |
| INTS6 | integrator complex subunit 6 | 0.0243145 |
| ACTN4 | actinin, alpha 4 | 0.0241023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.203297 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.13298 |
| MYO1E | myosin IE | -0.127739 |
| LMO7 | LIM domain 7 | -0.111428 |
| LAMB3 | laminin, beta 3 | -0.0970205 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0834938 |
| LAMC2 | laminin, gamma 2 | -0.0801388 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.0713072 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0686337 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0675993 |
| ATOSA | atos homolog A | -0.0672534 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.067241 |
| RBM47 | RNA binding motif protein 47 | -0.0663881 |
| SVIL | supervillin | -0.0643057 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0630506 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0595583 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0590897 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0584153 |
| S100A9 | S100 calcium binding protein A9 | -0.0582801 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0566234 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0551787 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0547025 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0534037 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0508215 |
| GRAMD2B | GRAM domain containing 2B | -0.050422 |
| ABHD17C | abhydrolase domain containing 17C | -0.0501704 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0495879 |
| TMCC3 | transmembrane and coiled-coil domain family 3 | -0.0491944 |
| RNF213 | ring finger protein 213 | -0.0491152 |
| VCAN | versican | -0.0490713 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0484881 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0483138 |
| TXNRD1 | thioredoxin reductase 1 | -0.0475275 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0474363 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0470976 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0470154 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0464129 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.0460986 |
| OSMR | oncostatin M receptor | -0.0449921 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0439969 |
| ZNF217 | zinc finger protein 217 | -0.0435205 |
| CLDN4 | claudin 4 | -0.0426489 |
| ANXA2 | annexin A2 | -0.0425666 |
| PRSS23 | protease, serine, 23 | -0.0421575 |
| GRAMD1B | GRAM domain containing 1B | -0.0405054 |
| FOXO1 | forkhead box O1 | -0.040391 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0399312 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0397886 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.039312 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0390893 |
| GLIS3 | GLIS family zinc finger 3 | -0.0387506 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0371402 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0370732 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0364202 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0362701 |
| TXNIP | thioredoxin interacting protein | -0.0360461 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.035842 |
| ERBIN | erbb2 interacting protein | -0.0357473 |
| DSG2 | desmoglein 2 | -0.0352949 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0352499 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0347087 |
| FOXO3 | forkhead box O3 | -0.0346794 |
| MYO5C | myosin VC | -0.0343686 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0341134 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0330092 |
| F11R | F11 receptor | -0.0328592 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.032318 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0318648 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0318102 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0315308 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0310993 |
| KRT17 | keratin 17, type I | -0.0310642 |
| TMEM87A | transmembrane protein 87A | -0.0304656 |
| CP | ceruloplasmin (ferroxidase) | -0.0303619 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0299062 |
| KYNU | kynureninase | -0.0298893 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0298605 |
| DENND2C | DENN/MADD domain containing 2C | -0.0298116 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0296292 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.028725 |
| S100A10 | S100 calcium binding protein A10 | -0.0287196 |
| SERINC1 | serine incorporator 1 | -0.0286266 |
| CUX1 | cut-like homeobox 1 | -0.0286083 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0285743 |
| TJP1 | tight junction protein 1 | -0.0284237 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0283745 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0283705 |
| AHNAK | AHNAK nucleoprotein | -0.028356 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0283418 |
| PLS3 | plastin 3 | -0.0281733 |
| TMSB10 | thymosin beta 10 | -0.028145 |
| TPM4 | tropomyosin 4 | -0.0277642 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0277339 |
| VCL | vinculin | -0.0276251 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0274517 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0274224 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0270046 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0267871 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0266856 |
| S100A11 | S100 calcium binding protein A11 | -0.0265529 |
