| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.205886 |
| KYNU | kynureninase | 0.146741 |
| PDE10A | phosphodiesterase 10A | 0.133307 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.124788 |
| EFNA5 | ephrin-A5 | 0.116468 |
| DST | dystonin | 0.115664 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.110457 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.106542 |
| MYOF | myoferlin | 0.0977014 |
| GDA | guanine deaminase | 0.097483 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0958688 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0953968 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0897499 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0844203 |
| ASPH | aspartate beta-hydroxylase | 0.0824354 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.077597 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0753599 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0717162 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0665993 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0652894 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0645129 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0644915 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0644322 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0615175 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0606719 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0605581 |
| COL5A2 | collagen, type V, alpha 2 | 0.0602152 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0593842 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0588945 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0553903 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.05489 |
| CD109 | CD109 molecule | 0.0540111 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0522928 |
| NEK7 | NIMA-related kinase 7 | 0.0512461 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0509759 |
| TXNRD1 | thioredoxin reductase 1 | 0.050804 |
| FNDC3B | fibronectin type III domain containing 3B | 0.050613 |
| VCL | vinculin | 0.0491705 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0483324 |
| PTEN | phosphatase and tensin homolog | 0.0482877 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.045287 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0447352 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0441575 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0440972 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.043659 |
| TBXT | T-box transcription factor T | 0.0430486 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0419075 |
| LAMA1 | laminin, alpha 1 | 0.0417819 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0413717 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0385774 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0371632 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0355893 |
| COPA | coatomer protein complex, subunit alpha | 0.0354639 |
| PLCB4 | phospholipase C, beta 4 | 0.0348509 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.034586 |
| HDAC4 | histone deacetylase 4 | 0.0340575 |
| CANX | calnexin | 0.0334854 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0333945 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0328121 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0322772 |
| RBM39 | RNA binding motif protein 39 | 0.0314022 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0309856 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0306978 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.030259 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.030068 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0295109 |
| PCBP2 | poly(rC) binding protein 2 | 0.0294225 |
| ATAD1 | ATPase family, AAA domain containing 1 | 0.0291636 |
| ENAH | enabled homolog (Drosophila) | 0.027183 |
| PALLD | palladin, cytoskeletal associated protein | 0.0269212 |
| SMAD2 | SMAD family member 2 | 0.0268859 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0266087 |
| HDLBP | high density lipoprotein binding protein | 0.0263386 |
| SMYD3 | SET and MYND domain containing 3 | 0.0262847 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0262145 |
| INTS6 | integrator complex subunit 6 | 0.0261946 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0260514 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0258936 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0255789 |
| RTN4 | reticulon 4 | 0.0254174 |
| CALR | calreticulin | 0.0250406 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0248948 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0246283 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0241925 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240865 |
| CTSC | cathepsin C | 0.0240473 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0239113 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0237967 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0234352 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0234146 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0231254 |
| WDR43 | WD repeat domain 43 | 0.0231067 |
| MFF | mitochondrial fission factor | 0.0230831 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0228896 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 0.0226717 |
| NBAS | neuroblastoma amplified sequence | 0.0225138 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0225063 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0224321 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0223042 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0223028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.148137 |
| FN1 | fibronectin 1 | -0.127862 |
| VIM | vimentin | -0.109551 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0898386 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0820747 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0772305 |
| TMSB10 | thymosin beta 10 | -0.0598918 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0593588 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0583778 |
| RPLP1 | ribosomal protein, large, P1 | -0.0567598 |
| PTMA | prothymosin, alpha | -0.0548767 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0546556 |
| CTSL | cathepsin L | -0.0546141 |
| RPS6 | ribosomal protein S6 | -0.0539821 |
| CDH13 | cadherin 13 | -0.0529025 |
| RPL37A | ribosomal protein L37a | -0.0489636 |
| RPL31 | ribosomal protein L31 | -0.0485037 |
| RPS3 | ribosomal protein S3 | -0.0464402 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0437391 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0435751 |
| RPS8 | ribosomal protein S8 | -0.042483 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0402315 |
| RPS24 | ribosomal protein S24 | -0.0391942 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0380123 |
| RPL35A | ribosomal protein L35a | -0.0379321 |
| STC1 | stanniocalcin 1 | -0.0364216 |
| RPL26 | ribosomal protein L26 | -0.0355925 |
| RPL38 | ribosomal protein L38 | -0.0344412 |
| LSAMP | limbic system-associated membrane protein | -0.0341151 |
| RPS27A | ribosomal protein S27a | -0.0333601 |
| RPS19 | ribosomal protein S19 | -0.0325876 |
| ENO1 | enolase 1, (alpha) | -0.031667 |
| RPL36A | ribosomal protein L36a | -0.0315815 |
| RPS29 | ribosomal protein S29 | -0.0314088 |
| RPS12 | ribosomal protein S12 | -0.0309203 |
| NRCAM | neuronal cell adhesion molecule | -0.0296585 |
| S100A6 | S100 calcium binding protein A6 | -0.0296525 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0289851 |
| NCKAP5 | NCK-associated protein 5 | -0.0288109 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0286681 |
| ESM1 | endothelial cell-specific molecule 1 | -0.028257 |
| RPL34 | ribosomal protein L34 | -0.0281746 |
| FTL | ferritin, light polypeptide | -0.0274157 |
| PCDH9 | protocadherin 9 | -0.0271261 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0269251 |
| RPS27 | ribosomal protein S27 | -0.0259231 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0257317 |
| RPLP2 | ribosomal protein, large, P2 | -0.0256645 |
| CCDC68 | coiled-coil domain containing 68 | -0.0248369 |
| UNC5D | unc-5 homolog D (C. elegans) | -0.0245546 |
| RPLP0 | ribosomal protein, large, P0 | -0.0241821 |
| RPL7A | ribosomal protein L7a | -0.0240021 |
| RPL9 | ribosomal protein L9 | -0.0237186 |
| HLA-B | major histocompatibility complex, class I, B | -0.0236902 |
| RPS25 | ribosomal protein S25 | -0.0227464 |
| RPS21 | ribosomal protein S21 | -0.0222128 |
| RPS16 | ribosomal protein S16 | -0.0221836 |
| RPL11 | ribosomal protein L11 | -0.0221091 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0218311 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0217248 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0215799 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0215378 |
| IER3 | immediate early response 3 | -0.0214946 |
| MT2A | metallothionein 2A | -0.0214919 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0214475 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0211777 |
| PLAUR | plasminogen activator, urokinase receptor | -0.020242 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0199928 |
| RPL19 | ribosomal protein L19 | -0.0199545 |
| RPL36 | ribosomal protein L36 | -0.0199462 |
| PRSS23 | protease, serine, 23 | -0.0198572 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.01984 |
| RPS23 | ribosomal protein S23 | -0.0195228 |
| TENM3 | teneurin transmembrane protein 3 | -0.0195041 |
| RPS13 | ribosomal protein S13 | -0.0194585 |
| S100A10 | S100 calcium binding protein A10 | -0.0194574 |
| SLK | STE20-like kinase | -0.0189212 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0187361 |
| HLA-A | major histocompatibility complex, class I, A | -0.0185803 |
| RPS14 | ribosomal protein S14 | -0.018394 |
| RPL37 | ribosomal protein L37 | -0.0182928 |
| PYGL | phosphorylase, glycogen, liver | -0.0182511 |
| TMSB4X | thymosin beta 4, X-linked | -0.0178391 |
| RPL12 | ribosomal protein L12 | -0.0177538 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0177003 |
| RPS17 | ribosomal protein S17 | -0.01739 |
| TENM2 | teneurin transmembrane protein 2 | -0.0173383 |
| MAP7 | microtubule-associated protein 7 | -0.0172391 |
| FOXC1 | forkhead box C1 | -0.0170266 |
| CLMP | CXADR-like membrane protein | -0.0167454 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0165563 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0163635 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.016252 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0161098 |
| RAI14 | retinoic acid induced 14 | -0.0157726 |
| SQSTM1 | sequestosome 1 | -0.0155369 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0154999 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0154867 |
| LMNA | lamin A/C | -0.0154848 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0153895 |
