| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.149282 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.111388 |
| HDAC9 | histone deacetylase 9 | 0.109815 |
| ZNF292 | zinc finger protein 292 | 0.106999 |
| COL5A2 | collagen, type V, alpha 2 | 0.104534 |
| PEG10 | paternally expressed 10 | 0.0978706 |
| PTMA | prothymosin, alpha | 0.0974172 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0953661 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0890397 |
| PDGFC | platelet derived growth factor C | 0.0842977 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0806681 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0779458 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0775549 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.076178 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0760935 |
| CALR | calreticulin | 0.0750882 |
| THBS1 | thrombospondin 1 | 0.0721107 |
| POTEF | POTE ankyrin domain family, member F | 0.0714511 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0676217 |
| PHIP | pleckstrin homology domain interacting protein | 0.0662864 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0659769 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0648775 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0637073 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0635445 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0631121 |
| FBXO11 | F-box protein 11 | 0.0629489 |
| MKI67 | marker of proliferation Ki-67 | 0.0609097 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0607581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0602953 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0595839 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0584513 |
| ITGAV | integrin, alpha V | 0.0583265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0565398 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0561338 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0560911 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0560145 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.055706 |
| JMJD1C | jumonji domain containing 1C | 0.0556135 |
| DST | dystonin | 0.0555569 |
| ZNF217 | zinc finger protein 217 | 0.0552404 |
| ENAH | enabled homolog (Drosophila) | 0.0549045 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0548551 |
| RBM39 | RNA binding motif protein 39 | 0.0538824 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0534219 |
| VIM | vimentin | 0.0527069 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0524689 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0521816 |
| APP | amyloid beta (A4) precursor protein | 0.0513145 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0508813 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.050821 |
| SRP54 | signal recognition particle 54kDa | 0.049256 |
| ACTG1 | actin gamma 1 | 0.048943 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0482772 |
| RDX | radixin | 0.0478406 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0474205 |
| MYO10 | myosin X | 0.0472106 |
| EMP1 | epithelial membrane protein 1 | 0.0471011 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0470668 |
| QKI | QKI, KH domain containing, RNA binding | 0.0469045 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0468288 |
| PDS5B | PDS5 cohesin associated factor B | 0.0463564 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0461019 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0460026 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0459383 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0453641 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0447937 |
| SHROOM3 | shroom family member 3 | 0.0446733 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0446011 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0444472 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.043989 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0434161 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0431875 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0431839 |
| MB21D2 | Mab-21 domain containing 2 | 0.0430164 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.04301 |
| NCKAP1 | NCK-associated protein 1 | 0.0429546 |
| RASAL2 | RAS protein activator like 2 | 0.0425948 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0413276 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0402337 |
| RLF | rearranged L-myc fusion | 0.0400693 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0397597 |
| USP25 | ubiquitin specific peptidase 25 | 0.0395642 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0394844 |
| FAM171B | family with sequence similarity 171, member B | 0.0394524 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.039398 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0393905 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0390622 |
| ANXA1 | annexin A1 | 0.0389929 |
| PLPP1 | phospholipid phosphatase 1 | 0.0387442 |
| RBM20 | RNA binding motif protein 20 | 0.0384106 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0382895 |
| CCN2 | cellular communication network factor 2 | 0.0382057 |
| SPAG9 | sperm associated antigen 9 | 0.0381145 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0376242 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0373072 |
| GPC4 | glypican 4 | 0.0372822 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0370235 |
| KIF5B | kinesin family member 5B | 0.0369596 |
| TENM3 | teneurin transmembrane protein 3 | 0.0363806 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0361089 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0407131 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0298865 |
| NEBL | nebulette | -0.0273876 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0259481 |
| PCDH7 | protocadherin 7 | -0.0245787 |
| FN1 | fibronectin 1 | -0.024513 |
| RPS13 | ribosomal protein S13 | -0.0240902 |
| RPL31 | ribosomal protein L31 | -0.0220959 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0218201 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0218177 |
| ASPH | aspartate beta-hydroxylase | -0.0215518 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0215505 |
| NDRG1 | N-myc downstream regulated 1 | -0.020466 |
| FTL | ferritin, light polypeptide | -0.0200921 |
| EFNA5 | ephrin-A5 | -0.0199335 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0189982 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0187672 |
| ATXN1 | ataxin 1 | -0.018141 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0179244 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0178103 |
| ABR | active BCR-related | -0.0177842 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0175318 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0174794 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.016827 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0166518 |
| RUNX1 | runt-related transcription factor 1 | -0.0166368 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.016302 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0162129 |
| RPLP1 | ribosomal protein, large, P1 | -0.0161384 |
| PDE10A | phosphodiesterase 10A | -0.016124 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.015675 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0155242 |
| GUK1 | guanylate kinase 1 | -0.0150741 |
| ANO6 | anoctamin 6 | -0.01507 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0150649 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0149088 |
| ZNF638 | zinc finger protein 638 | -0.014632 |
| RPS25 | ribosomal protein S25 | -0.0146145 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0141714 |
| BPTF | bromodomain PHD finger transcription factor | -0.0141142 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | -0.0140555 |
| WDR45B | WD repeat domain 45B | -0.0140029 |
| ATP9A | ATPase, class II, type 9A | -0.0139918 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0139054 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0138682 |
| RAB6A | RAB6A, member RAS oncogene family | -0.013812 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0135728 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0135674 |
| DLGAP3 | discs, large (Drosophila) homolog-associated protein 3 | -0.0133658 |
| TRAPPC10 | trafficking protein particle complex 10 | -0.0133051 |
| BBX | bobby sox homolog (Drosophila) | -0.0132913 |
| TP53 | tumor protein p53 | -0.0132538 |
| FST | follistatin | -0.0132475 |
| SPOP | speckle-type POZ protein | -0.0132375 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0132154 |
| ATRN | attractin | -0.0131586 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0129347 |
| FBXO27 | F-box protein 27 | -0.0129317 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.012848 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0127467 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 | -0.0127036 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0126798 |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | -0.0125673 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0125094 |
| CUX1 | cut-like homeobox 1 | -0.0124757 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.012365 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0123309 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0123055 |
| NTNG2 | netrin G2 | -0.0122917 |
| S100A9 | S100 calcium binding protein A9 | -0.0122607 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | -0.012227 |
| JAKMIP2 | janus kinase and microtubule interacting protein 2 | -0.012208 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0121714 |
| RPS28 | ribosomal protein S28 | -0.0119849 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -0.0119614 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | -0.0119581 |
| RNF149 | ring finger protein 149 | -0.0119327 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0119316 |
| ZMAT2 | zinc finger, matrin-type 2 | -0.0119115 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | -0.0118827 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0118655 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0118498 |
| E2F3 | E2F transcription factor 3 | -0.0117846 |
| IER3 | immediate early response 3 | -0.0117772 |
| HPCAL1 | hippocalcin-like 1 | -0.0116967 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0116417 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0116081 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | -0.0115784 |
| C2ORF42 | chromosome 2 open reading frame 42 | -0.0115722 |
| FBXO34 | F-box protein 34 | -0.0115673 |
| SAR1B | secretion associated, Ras related GTPase 1B | -0.0115352 |
| RPS19 | ribosomal protein S19 | -0.0114761 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0113919 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0113667 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0113398 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0112866 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | -0.0112861 |
| ZBTB44 | zinc finger and BTB domain containing 44 | -0.0112714 |
| TUBA1A | tubulin, alpha 1a | -0.0112348 |
| ATP5MJ | ATP synthase membrane subunit j | -0.0111927 |
