| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Methylthiouracil_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.221776 |
| B2M | beta-2-microglobulin | 0.155858 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0919574 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.063504 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0614652 |
| LOXL2 | lysyl oxidase-like 2 | 0.0595485 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0563211 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0558129 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0543943 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0537374 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0527687 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0469392 |
| DSCAM | Down syndrome cell adhesion molecule | 0.043986 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0406353 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0405046 |
| MT2A | metallothionein 2A | 0.0404368 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0398376 |
| NDRG1 | N-myc downstream regulated 1 | 0.0393387 |
| SRPK2 | SRSF protein kinase 2 | 0.0384856 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0368332 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0365419 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.0362239 |
| VIM | vimentin | 0.0361218 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0355805 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0349387 |
| COPA | coatomer protein complex, subunit alpha | 0.0343766 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.034299 |
| LOX | lysyl oxidase | 0.0342266 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0325819 |
| HELZ | helicase with zinc finger | 0.0324111 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0319459 |
| RNF24 | ring finger protein 24 | 0.031464 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0307362 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0305255 |
| OGA | O-GlcNAcase | 0.0299658 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0297492 |
| SETD5 | SET domain containing 5 | 0.0296053 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0295985 |
| ADM | adrenomedullin | 0.0295038 |
| COL5A1 | collagen, type V, alpha 1 | 0.0294599 |
| TPM3 | tropomyosin 3 | 0.0290114 |
| SEC24A | SEC24 family member A | 0.0288882 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0288294 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0281665 |
| TXNIP | thioredoxin interacting protein | 0.0279453 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0278786 |
| ZNF292 | zinc finger protein 292 | 0.0278422 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0277355 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0276767 |
| CD82 | CD82 molecule | 0.0276133 |
| SRP54 | signal recognition particle 54kDa | 0.02755 |
| ANLN | anillin, actin binding protein | 0.027413 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0269065 |
| SPAG9 | sperm associated antigen 9 | 0.0268046 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0265019 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0263824 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0263357 |
| ANXA5 | annexin A5 | 0.0260126 |
| CADM1 | cell adhesion molecule 1 | 0.0258892 |
| S100A10 | S100 calcium binding protein A10 | 0.0257953 |
| CLTC | clathrin, heavy chain (Hc) | 0.0257481 |
| TAGLN2 | transgelin 2 | 0.0257255 |
| RNF145 | ring finger protein 145 | 0.0255118 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0255083 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0254114 |
| TFG | TRK-fused gene | 0.0251117 |
| SNX13 | sorting nexin 13 | 0.0250695 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0249759 |
| XPO1 | exportin 1 | 0.024821 |
| SDC4 | syndecan 4 | 0.0248089 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0244085 |
| HLA-B | major histocompatibility complex, class I, B | 0.0243655 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0243292 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 0.0236175 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0234797 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0234535 |
| ANXA1 | annexin A1 | 0.0232999 |
| SUCO | SUN domain containing ossification factor | 0.0229487 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0229445 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0228571 |
| CALR | calreticulin | 0.0225163 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0222921 |
| MORC3 | MORC family CW-type zinc finger 3 | 0.0221456 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0219022 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0218987 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0218917 |
| RLF | rearranged L-myc fusion | 0.0218514 |
| USP34 | ubiquitin specific peptidase 34 | 0.0216841 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0216644 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0216594 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.021596 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.021349 |
| CUL3 | cullin 3 | 0.0212127 |
| SMAD3 | SMAD family member 3 | 0.0211817 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0210007 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0208429 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0208392 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0208183 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0207704 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0207696 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.126348 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0803221 |
| PTMA | prothymosin, alpha | -0.0590761 |
| FN1 | fibronectin 1 | -0.0522913 |
| EXT1 | exostosin glycosyltransferase 1 | -0.050889 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0507951 |
| PDE10A | phosphodiesterase 10A | -0.0450486 |
| RPS24 | ribosomal protein S24 | -0.0434802 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0414883 |
| TMSB10 | thymosin beta 10 | -0.0403862 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0401738 |
| MORF4L2 | mortality factor 4 like 2 | -0.0383834 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0376751 |
| DST | dystonin | -0.0358734 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0347574 |
| STC1 | stanniocalcin 1 | -0.0345688 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0333094 |
| JMJD1C | jumonji domain containing 1C | -0.0318045 |
| RPS19 | ribosomal protein S19 | -0.030985 |
| RAD51B | RAD51 paralog B | -0.0301011 |
| RPS8 | ribosomal protein S8 | -0.0292753 |
| RPLP2 | ribosomal protein, large, P2 | -0.0289943 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0285072 |
| RPL5 | ribosomal protein L5 | -0.0284771 |
| PRDX1 | peroxiredoxin 1 | -0.0282476 |
| FOSL1 | FOS-like antigen 1 | -0.0282217 |
| RPL28 | ribosomal protein L28 | -0.0278669 |
| RPLP1 | ribosomal protein, large, P1 | -0.0278338 |
| RNF216 | ring finger protein 216 | -0.0277138 |
| RPL26 | ribosomal protein L26 | -0.0275612 |
| GSE1 | Gse1 coiled-coil protein | -0.0273712 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0271172 |
| GPC6 | glypican 6 | -0.0270988 |
| MT1X | metallothionein 1X | -0.0268113 |
| RPL12 | ribosomal protein L12 | -0.0267424 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0264395 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0261226 |
| RRBP1 | ribosome binding protein 1 | -0.0255187 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0255176 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0252567 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | -0.0252298 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0246395 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0244801 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.023861 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0237493 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0236595 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0233879 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.023238 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0232073 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.022954 |
| PRMT2 | protein arginine methyltransferase 2 | -0.0228924 |
| TUBB | tubulin, beta class I | -0.0228528 |
| S100A9 | S100 calcium binding protein A9 | -0.0228313 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0228157 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0227225 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0227014 |
| RPL37A | ribosomal protein L37a | -0.0226242 |
| GNAS | GNAS complex locus | -0.0226047 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0225365 |
| PCNX4 | pecanex 4 | -0.0223531 |
| ITGAV | integrin, alpha V | -0.0221217 |
| HMGB1 | high mobility group box 1 | -0.0221086 |
| RPL13A | ribosomal protein L13a | -0.0220024 |
| NUBPL | nucleotide binding protein-like | -0.021618 |
| NF1 | neurofibromin 1 | -0.0215317 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0214615 |
| RACK1 | receptor for activated C kinase 1 | -0.0212719 |
| RPS5 | ribosomal protein S5 | -0.0211355 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.021045 |
| NABP1 | nucleic acid binding protein 1 | -0.0209849 |
| RPL35A | ribosomal protein L35a | -0.0209096 |
| RPL19 | ribosomal protein L19 | -0.0207366 |
| VCL | vinculin | -0.020604 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0205731 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0203687 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0202373 |
| FMNL2 | formin-like 2 | -0.0200596 |
| HMGA2 | high mobility group AT-hook 2 | -0.0199469 |
| MPG | N-methylpurine-DNA glycosylase | -0.0197711 |
| TPGS2 | tubulin polyglutamylase complex subunit 2 | -0.0196282 |
| TBC1D32 | TBC1 domain family, member 32 | -0.0195614 |
| SON | SON DNA binding protein | -0.0194797 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0194424 |
| RPL38 | ribosomal protein L38 | -0.0194001 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0193284 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0192219 |
| PRKCA | protein kinase C, alpha | -0.0190995 |
| SMYD3 | SET and MYND domain containing 3 | -0.0190732 |
| RPL7 | ribosomal protein L7 | -0.0189619 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0189471 |
| TLK1 | tousled-like kinase 1 | -0.0187776 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0187251 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | -0.0186247 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.018576 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.018467 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0184147 |
| COL1A1 | collagen, type I, alpha 1 | -0.0183368 |
| FTL | ferritin, light polypeptide | -0.0181803 |
| HDAC9 | histone deacetylase 9 | -0.0180988 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0180954 |
