| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Methylthiouracil perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Methylthiouracil_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0782793 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0589798 |
| TXNRD1 | thioredoxin reductase 1 | 0.0574635 |
| RBM39 | RNA binding motif protein 39 | 0.0569851 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0531883 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0470793 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0462964 |
| DIAPH3 | diaphanous-related formin 3 | 0.0432674 |
| MKI67 | marker of proliferation Ki-67 | 0.0425793 |
| ANLN | anillin, actin binding protein | 0.0424687 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0420406 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0420402 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0391977 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0382153 |
| GOLGA4 | golgin A4 | 0.0379508 |
| YBX3 | Y box binding protein 3 | 0.0379243 |
| ANXA1 | annexin A1 | 0.0376122 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0370178 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0357862 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0356551 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0354789 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0353609 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0339921 |
| CENPF | centromere protein F, 350/400kDa | 0.0339763 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0337745 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0337738 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0337627 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0336511 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0336008 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0335586 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0335581 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0331074 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0328537 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0324384 |
| ANXA2 | annexin A2 | 0.0322214 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0309999 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0306315 |
| CANX | calnexin | 0.030014 |
| SETD5 | SET domain containing 5 | 0.0295461 |
| TPR | translocated promoter region, nuclear basket protein | 0.0292085 |
| POTEF | POTE ankyrin domain family, member F | 0.0289506 |
| CPNE1 | copine I | 0.0287729 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.028106 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0280081 |
| KIAA1328 | KIAA1328 | 0.0276338 |
| ECT2 | epithelial cell transforming 2 | 0.0268923 |
| SGO2 | shugoshin 2 | 0.0267155 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0263897 |
| SMC4 | structural maintenance of chromosomes 4 | 0.026108 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0260982 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0260154 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0257666 |
| UTRN | utrophin | 0.0257187 |
| MSN | moesin | 0.0256102 |
| ATP13A3 | ATPase type 13A3 | 0.0252834 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0249312 |
| CAPRIN1 | cell cycle associated protein 1 | 0.024545 |
| TNPO1 | transportin 1 | 0.0245033 |
| GOLGA2 | golgin A2 | 0.0240719 |
| CALU | calumenin | 0.0240638 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0239678 |
| PUM2 | pumilio RNA-binding family member 2 | 0.023923 |
| CLINT1 | clathrin interactor 1 | 0.0238481 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0238427 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0237228 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0236712 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0234555 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0234208 |
| CEP250 | centrosomal protein 250kDa | 0.0233682 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0230947 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0229292 |
| HIPK1 | homeodomain interacting protein kinase 1 | 0.0228524 |
| IDS | iduronate 2-sulfatase | 0.0226684 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.02266 |
| TBC1D15 | TBC1 domain family, member 15 | 0.0223446 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0223023 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0222952 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.022223 |
| CLTC | clathrin, heavy chain (Hc) | 0.0220956 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0218396 |
| PGM3 | phosphoglucomutase 3 | 0.0217755 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0217127 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0216978 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0215377 |
| SET | SET nuclear proto-oncogene | 0.0214129 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0212974 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0212021 |
| KIAA1958 | KIAA1958 | 0.0211098 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0210107 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0208628 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0208554 |
| SEPTIN2 | septin 2 | 0.0207818 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0207792 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0207689 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0207497 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0207339 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0206977 |
| CENPE | centromere protein E, 312kDa | 0.0206475 |
| PHIP | pleckstrin homology domain interacting protein | 0.020544 |
| WBP11 | WW domain binding protein 11 | 0.020405 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.0901289 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0650159 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0645355 |
| FNDC3B | fibronectin type III domain containing 3B | -0.058178 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0579168 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0556769 |
| HMGA2 | high mobility group AT-hook 2 | -0.0521562 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0511227 |
| PTMA | prothymosin, alpha | -0.0504322 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.045875 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0422772 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0420036 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0394515 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0378052 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0367887 |
| IGF2 | insulin-like growth factor 2 | -0.0364096 |
| RPLP1 | ribosomal protein, large, P1 | -0.0345982 |
| RAI14 | retinoic acid induced 14 | -0.0343364 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0340181 |
| VIM | vimentin | -0.0337605 |
| RIGI | RNA sensor RIG-I | -0.0327415 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0325341 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0317027 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.031655 |
| RPS25 | ribosomal protein S25 | -0.0311153 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0295701 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.028979 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0288863 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0287614 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0283579 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0283041 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0280803 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0278103 |
| GPHN | gephyrin | -0.027553 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.027112 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0270984 |
| EGR1 | early growth response 1 | -0.0270409 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0269724 |
| FMNL2 | formin-like 2 | -0.0268211 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266345 |
| PCED1B | PC-esterase domain containing 1B | -0.0264744 |
| PRR16 | proline rich 16 | -0.0261236 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.026071 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0257323 |
| GPC5 | glypican 5 | -0.0256887 |
| PRSS23 | protease, serine, 23 | -0.025148 |
| ZFHX3 | zinc finger homeobox 3 | -0.0246426 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0243966 |
| SVIL | supervillin | -0.0242846 |
| ANGPTL4 | angiopoietin-like 4 | -0.0239778 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0237952 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0232099 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0230933 |
| STXBP1 | syntaxin binding protein 1 | -0.0227016 |
| ZBTB7A | zinc finger and BTB domain containing 7A | -0.022671 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0225947 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0225014 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0224628 |
| RPL31 | ribosomal protein L31 | -0.0221382 |
| LRRC49 | leucine rich repeat containing 49 | -0.0217348 |
| FMN1 | formin 1 | -0.0215603 |
| EEA1 | early endosome antigen 1 | -0.021423 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0210395 |
| FAM3C | family with sequence similarity 3, member C | -0.020894 |
| SDC4 | syndecan 4 | -0.0207416 |
| RPS20 | ribosomal protein S20 | -0.0203784 |
| PRKCA | protein kinase C, alpha | -0.0200905 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | -0.0198431 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0196926 |
| EFNA5 | ephrin-A5 | -0.0193444 |
| IER3 | immediate early response 3 | -0.0192738 |
| GPC6 | glypican 6 | -0.0191131 |
| PLEK2 | pleckstrin 2 | -0.0190108 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0188839 |
| RPL37A | ribosomal protein L37a | -0.018863 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0183822 |
| RSF1 | remodeling and spacing factor 1 | -0.0183229 |
| RPS12 | ribosomal protein S12 | -0.0182997 |
| RPL35A | ribosomal protein L35a | -0.0182878 |
| NRG1 | neuregulin 1 | -0.0181485 |
| WWOX | WW domain containing oxidoreductase | -0.0180477 |
| ATG7 | autophagy related 7 | -0.0180068 |
| HMGA1 | high mobility group AT-hook 1 | -0.0178252 |
| ENO1 | enolase 1, (alpha) | -0.0177822 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0177802 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0176853 |
| NALCN | sodium leak channel, non selective | -0.0175912 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0174773 |
| EGFR | epidermal growth factor receptor | -0.0174586 |
| ABR | active BCR-related | -0.0174049 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0173262 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0172922 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.016971 |
| RPS17 | ribosomal protein S17 | -0.0169093 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0168252 |
| MYO10 | myosin X | -0.0165225 |
| DNER | delta/notch-like EGF repeat containing | -0.0160928 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0160918 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0160823 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.015901 |
