Metoprolol Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1. (Chemical Entities of Biological Interest Ontology, CHEBI_6904)
External Link http://ctdbase.org/detail.go?type=chem&acc=D008790
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Genes

47 genes/proteins interacting with the chemical Metoprolol from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADRA2C adrenoceptor alpha 2C
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARRB2 arrestin, beta 2
BCL2L1 BCL2-like 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT1B carnitine palmitoyltransferase 1B (muscle)
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
G6PD glucose-6-phosphate dehydrogenase
GATA4 GATA binding protein 4
GJA1 gap junction protein, alpha 1, 43kDa
GRK4 G protein-coupled receptor kinase 4
GRK5 G protein-coupled receptor kinase 5
HMOX1 heme oxygenase 1
IL1A interleukin 1, alpha
JPH2 junctophilin 2
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
MEF2A myocyte enhancer factor 2A
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
ODC1 ornithine decarboxylase 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
REN renin
RYR2 ryanodine receptor 2 (cardiac)
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SPN sialophorin
TNF tumor necrosis factor
USF2 upstream transcription factor 2, c-fos interacting
VEGFA vascular endothelial growth factor A