Mevastatin Gene Set

Dataset DrugBank Drug Targets
Category physical interactions
Type drug
Description A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group and in which the lactone moiety has been hydrolysed to the corresponding delta-hydroxy-carboxylic acid. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. (Chemical Entities of Biological Interest Ontology, CHEBI_34848)
External Link http://www.drugbank.ca/drugs/DB06693
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Genes

2 interacting proteins for the Mevastatin drug from the curated DrugBank Drug Targets dataset.

Symbol Name
CES1 carboxylesterase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase