| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/4184 |
| Similar Terms | |
| Downloads & Tools |
198 proteins with high or low expression in Mianserin relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KLHL23 | kelch-like family member 23 | 1.15 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 1.02 |
| SH2B3 | SH2B adaptor protein 3 | 1.0 |
| LMOD1 | leiomodin 1 (smooth muscle) | 0.73 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 0.65 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.55 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.55 |
| CCDC66 | coiled-coil domain containing 66 | 0.55 |
| TDRD9 | tudor domain containing 9 | 0.54 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.53 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.52 |
| FBXO46 | F-box protein 46 | 0.52 |
| CBY1 | chibby homolog 1 (Drosophila) | 0.51 |
| NPHP1 | nephronophthisis 1 (juvenile) | 0.5 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) | 0.49 |
| HBB | hemoglobin, beta | 0.49 |
| TRIB1 | tribbles pseudokinase 1 | 0.48 |
| TSPAN3 | tetraspanin 3 | 0.47 |
| SLC38A2 | solute carrier family 38, member 2 | 0.47 |
| SRRD | SRR1 domain containing | 0.47 |
| HAS3 | hyaluronan synthase 3 | 0.46 |
| CD63 | CD63 molecule | 0.45 |
| PPHLN1 | periphilin 1 | 0.44 |
| ZBTB14 | zinc finger and BTB domain containing 14 | 0.43 |
| ZNF165 | zinc finger protein 165 | 0.42 |
| ZNF408 | zinc finger protein 408 | 0.41 |
| TMEM64 | transmembrane protein 64 | 0.39 |
| ANKRD13D | ankyrin repeat domain 13 family, member D | 0.39 |
| CIAO2A | cytosolic iron-sulfur assembly component 2A | 0.38 |
| ANKRD20A4 | ankyrin repeat domain 20 family, member A4 | 0.38 |
| GSKIP | GSK3B interacting protein | 0.38 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.37 |
| FAM171A1 | family with sequence similarity 171, member A1 | 0.37 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.37 |
| HOXB7 | homeobox B7 | 0.36 |
| KIAA1324L | KIAA1324-like | 0.36 |
| ZNF2 | zinc finger protein 2 | 0.36 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.35 |
| CCDC85B | coiled-coil domain containing 85B | 0.35 |
| CREBZF | CREB/ATF bZIP transcription factor | 0.34 |
| CCDC85C | coiled-coil domain containing 85C | 0.34 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.34 |
| WTIP | Wilms tumor 1 interacting protein | 0.34 |
| PLA2G15 | phospholipase A2, group XV | 0.34 |
| NES | nestin | 0.34 |
| ODC1 | ornithine decarboxylase 1 | 0.34 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | 0.33 |
| NDFIP2 | Nedd4 family interacting protein 2 | 0.33 |
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.33 |
| HAUS1 | HAUS augmin-like complex, subunit 1 | 0.33 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.32 |
| FAM102B | family with sequence similarity 102, member B | 0.32 |
| MIEN1 | migration and invasion enhancer 1 | 0.32 |
| GLCCI1 | glucocorticoid induced 1 | 0.32 |
| CD320 | CD320 molecule | 0.32 |
| WNT10B | wingless-type MMTV integration site family, member 10B | 0.32 |
| LMTK2 | lemur tyrosine kinase 2 | 0.32 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.32 |
| WDR34 | WD repeat domain 34 | 0.31 |
| PPCDC | phosphopantothenoylcysteine decarboxylase | 0.31 |
| RPE | ribulose-5-phosphate-3-epimerase | 0.31 |
| MED22 | mediator complex subunit 22 | 0.3 |
| GRHL1 | grainyhead-like 1 (Drosophila) | 0.3 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.3 |
| SPPL2A | signal peptide peptidase like 2A | 0.3 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.3 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.3 |
| LTBP3 | latent transforming growth factor beta binding protein 3 | 0.29 |
| PCSK9 | proprotein convertase subtilisin/kexin type 9 | 0.29 |
| DUSP6 | dual specificity phosphatase 6 | 0.29 |
| SMAD1 | SMAD family member 1 | 0.29 |
| ZNF518A | zinc finger protein 518A | 0.29 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.29 |
| RNF167 | ring finger protein 167 | 0.29 |
| CFAP54 | cilia and flagella associated 54 | 0.29 |
| UCK2 | uridine-cytidine kinase 2 | 0.29 |
| MT1F | metallothionein 1F | 0.29 |
| ZUP1 | zinc finger containing ubiquitin peptidase 1 | 0.28 |
| ZNF92 | zinc finger protein 92 | 0.28 |
| RGN | regucalcin | 0.28 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | 0.28 |
| RPLP1 | ribosomal protein, large, P1 | 0.28 |
| ACTBL2 | actin, beta-like 2 | 0.28 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.28 |
| FBXO28 | F-box protein 28 | 0.28 |
| DUSP5 | dual specificity phosphatase 5 | 0.27 |
| KIF26A | kinesin family member 26A | 0.27 |
| GPATCH2L | G patch domain containing 2-like | 0.27 |
| RAD9A | RAD9 homolog A (S. pombe) | 0.27 |
| SP4 | Sp4 transcription factor | 0.27 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.27 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.27 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.27 |
| C2ORF42 | chromosome 2 open reading frame 42 | 0.27 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.27 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | 0.27 |
| CGNL1 | cingulin-like 1 | 0.27 |
| FAM135A | family with sequence similarity 135, member A | 0.27 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.27 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.27 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | -1.06 |
| LAMA3 | laminin, alpha 3 | -0.69 |
| RCAN1 | regulator of calcineurin 1 | -0.64 |
| CPE | carboxypeptidase E | -0.62 |
| APOE | apolipoprotein E | -0.61 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | -0.6 |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 | -0.58 |
| NAAA | N-acylethanolamine acid amidase | -0.56 |
| ARHGAP44 | Rho GTPase activating protein 44 | -0.54 |
| NEU1 | sialidase 1 (lysosomal sialidase) | -0.53 |
| PKHD1L1 | polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 | -0.52 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.52 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -0.51 |
| PRR36 | proline rich 36 | -0.5 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | -0.5 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.48 |
| PLK2 | polo-like kinase 2 | -0.47 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.47 |
| F5 | coagulation factor V (proaccelerin, labile factor) | -0.45 |
| GATA2 | GATA binding protein 2 | -0.45 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.45 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.43 |
| FAM241B | family with sequence similarity 241 member B | -0.43 |
| MTERF2 | mitochondrial transcription termination factor 2 | -0.42 |
| DOCK4 | dedicator of cytokinesis 4 | -0.41 |
| PHETA1 | PH domain containing endocytic trafficking adaptor 1 | -0.41 |
| SHROOM1 | shroom family member 1 | -0.4 |
| LIPA | lipase A, lysosomal acid, cholesterol esterase | -0.39 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.39 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.38 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | -0.36 |
| KDF1 | keratinocyte differentiation factor 1 | -0.36 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.36 |
| SYTL2 | synaptotagmin-like 2 | -0.35 |
| RETREG1 | reticulophagy regulator 1 | -0.34 |
| PRX | periaxin | -0.33 |
| SYT17 | synaptotagmin XVII | -0.33 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | -0.33 |
| VAMP4 | vesicle-associated membrane protein 4 | -0.33 |
| LPIN3 | lipin 3 | -0.32 |
| SLC22A18 | solute carrier family 22, member 18 | -0.32 |
| VTN | vitronectin | -0.31 |
| FAM117A | family with sequence similarity 117, member A | -0.31 |
| FGGY | FGGY carbohydrate kinase domain containing | -0.31 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.31 |
| ZFP36 | ZFP36 ring finger protein | -0.3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 | -0.29 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.29 |
| LYRM1 | LYR motif containing 1 | -0.29 |
| SLC25A44 | solute carrier family 25, member 44 | -0.29 |
| WHAMM | WAS protein homolog associated with actin, golgi membranes and microtubules | -0.29 |
| LPIN1 | lipin 1 | -0.29 |
| TATDN2 | TatD DNase domain containing 2 | -0.29 |
| TMOD2 | tropomodulin 2 (neuronal) | -0.29 |
| ABHD3 | abhydrolase domain containing 3 | -0.29 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.29 |
| HAL | histidine ammonia-lyase | -0.28 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | -0.28 |
| SESN1 | sestrin 1 | -0.28 |
| TBC1D25 | TBC1 domain family, member 25 | -0.28 |
| METTL25 | methyltransferase like 25 | -0.28 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.28 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) | -0.28 |
| ZNF490 | zinc finger protein 490 | -0.28 |
| PDZD11 | PDZ domain containing 11 | -0.28 |
| TMEM120A | transmembrane protein 120A | -0.28 |
| PLAUR | plasminogen activator, urokinase receptor | -0.27 |
| CCND3 | cyclin D3 | -0.27 |
| CCDC57 | coiled-coil domain containing 57 | -0.27 |
| PGBD2 | piggyBac transposable element derived 2 | -0.27 |
| ABHD13 | abhydrolase domain containing 13 | -0.27 |
| FAS | Fas cell surface death receptor | -0.27 |
| PLEK | pleckstrin | -0.27 |
| SLC16A6 | solute carrier family 16, member 6 | -0.27 |
| FBXO44 | F-box protein 44 | -0.27 |
| CDK18 | cyclin-dependent kinase 18 | -0.26 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.26 |
| HBA1 | hemoglobin, alpha 1 | -0.26 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | -0.26 |
| GGT2 | gamma-glutamyltransferase 2 | -0.26 |
| TP53 | tumor protein p53 | -0.26 |
| SPHK2 | sphingosine kinase 2 | -0.26 |
| XBP1 | X-box binding protein 1 | -0.26 |
| GRAMD2B | GRAM domain containing 2B | -0.26 |
| C18ORF32 | chromosome 18 open reading frame 32 | -0.26 |
| ATP5PF | ATP synthase peripheral stalk subunit F6 | -0.25 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.25 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) | -0.25 |
| TMEM222 | transmembrane protein 222 | -0.25 |
| PRDM16 | PR domain containing 16 | -0.25 |
| FDXR | ferredoxin reductase | -0.25 |
| RAET1G | retinoic acid early transcript 1G | -0.25 |
| CRY2 | cryptochrome circadian clock 2 | -0.25 |
| IL27RA | interleukin 27 receptor, alpha | -0.25 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.25 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.25 |
| HSPA12B | heat shock 70kD protein 12B | -0.25 |
| PPT1 | palmitoyl-protein thioesterase 1 | -0.25 |
