Miconazole Gene Set

Dataset HMDB Metabolites of Enzymes
Category physical interactions
Type metabolite
Description A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. (Chemical Entities of Biological Interest Ontology, CHEBI_6923)
External Link http://www.hmdb.ca/metabolites/HMDB15242
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Genes

25 interacting proteins for the Miconazole metabolite from the curated HMDB Metabolites of Enzymes dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNH7 potassium channel, voltage gated eag related subfamily H, member 7
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)