Microfibril Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins. (Gene Ontology, GO_0001527)
External Link http://amigo.geneontology.org/amigo/term/GO:0001527
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Genes

12 proteins localized to the Microfibril cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FBN1 fibrillin 1 5.0
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 5.0
FBN2 fibrillin 2 5.0
MFAP1 microfibrillar-associated protein 1 5.0
ADAMTSL5 ADAMTS-like 5 5.0
LTBP4 latent transforming growth factor beta binding protein 4 4.0
MFAP2 microfibrillar-associated protein 2 4.0
MFAP4 microfibrillar-associated protein 4 4.0
MFAP5 microfibrillar associated protein 5 4.0
THSD4 thrombospondin, type I, domain containing 4 4.0
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 4.0
LTBP1 latent transforming growth factor beta binding protein 1 4.0