Microneme Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell. (Gene Ontology, GO_0020009)
External Link http://amigo.geneontology.org/amigo/term/GO:0020009
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Genes

769 proteins co-occuring with the Microneme cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
CD99 CD99 molecule 3.281
MST1R macrophage stimulating 1 receptor 3.234
ATAD1 ATPase family, AAA domain containing 1 2.809
SUB1 SUB1 homolog (S. cerevisiae) 2.709
DHFR dihydrofolate reductase 2.649
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 2.549
MICOS13 mitochondrial contact site and cristae organizing system subunit 13 2.512
ERV3-1 endogenous retrovirus group 3, member 1 2.506
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.503
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.478
PLP1 proteolipid protein 1 2.431
ERVW-1 endogenous retrovirus group W, member 1 2.429
MYH14 myosin, heavy chain 14, non-muscle 2.388
MORN1 MORN repeat containing 1 2.367
CD9 CD9 molecule 2.353
ZNF395 zinc finger protein 395 2.27
ROM1 retinal outer segment membrane protein 1 2.244
SHLD1 shieldin complex subunit 1 2.194
RAP2A RAP2A, member of RAS oncogene family 2.191
SORT1 sortilin 1 2.174
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2.173
PFN4 profilin family, member 4 2.168
PFN3 profilin 3 2.166
L1CAM L1 cell adhesion molecule 2.155
RHCE Rh blood group, CcEe antigens 2.129
BSG basigin (Ok blood group) 2.115
IFNG interferon, gamma 2.111
BAG1 BCL2-associated athanogene 2.108
CSE1L CSE1 chromosome segregation 1-like (yeast) 2.107
CD44 CD44 molecule (Indian blood group) 2.105
PCSK6 proprotein convertase subtilisin/kexin type 6 2.09
PFN1 profilin 1 2.083
MYO1B myosin IB 2.074
DHFR2 dihydrofolate reductase 2 2.025
FBF1 Fas (TNFRSF6) binding factor 1 1.989
RAB5C RAB5C, member RAS oncogene family 1.989
TAAR6 trace amine associated receptor 6 1.982
DNAAF2 dynein, axonemal, assembly factor 2 1.967
TAMALIN trafficking regulator and scaffold protein tamalin 1.964
MXRA8 matrix-remodelling associated 8 1.951
GYPC glycophorin C (Gerbich blood group) 1.945
LGALSL lectin, galactoside-binding-like 1.942
VWA1 von Willebrand factor A domain containing 1 1.937
RHD Rh blood group, D antigen 1.935
MAPK15 mitogen-activated protein kinase 15 1.921
CD2 CD2 molecule 1.918
CETN2 centrin, EF-hand protein, 2 1.899
RAB5A RAB5A, member RAS oncogene family 1.892
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.866
HSPA4 heat shock 70kDa protein 4 1.857
MAGEH1 melanoma antigen family H1 1.851
SENP7 SUMO1/sentrin specific peptidase 7 1.85
CD8A CD8a molecule 1.843
GYPB glycophorin B (MNS blood group) 1.836
CHIT1 chitinase 1 (chitotriosidase) 1.834
CALML3 calmodulin-like 3 1.821
CTRB2 chymotrypsinogen B2 1.814
LOC102724560 cystathionine beta-synthase 1.813
CD4 CD4 molecule 1.812
PLEK2 pleckstrin 2 1.812
CTRB1 chymotrypsinogen B1 1.809
EGF epidermal growth factor 1.808
PLEK pleckstrin 1.808
CALML6 calmodulin-like 6 1.804
CALML4 calmodulin-like 4 1.804
CALML5 calmodulin-like 5 1.803
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 1.793
PRKG1 protein kinase, cGMP-dependent, type I 1.784
IL10 interleukin 10 1.755
CTSL cathepsin L 1.754
VWF von Willebrand factor 1.742
CETN1 centrin, EF-hand protein, 1 1.734
HSPB6 heat shock protein, alpha-crystallin-related, B6 1.731
CHIA chitinase, acidic 1.705
CD59 CD59 molecule, complement regulatory protein 1.703
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.694
NEK4 NIMA-related kinase 4 1.694
RAB5B RAB5B, member RAS oncogene family 1.693
PARL presenilin associated, rhomboid-like 1.693
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.69
APOA5 apolipoprotein A-V 1.68
ADCY9 adenylate cyclase 9 1.664
PXDNL peroxidasin-like 1.66
PXDN peroxidasin 1.658
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 1.654
IL4 interleukin 4 1.641
CENPV centromere protein V 1.635
SECISBP2 SECIS binding protein 2 1.627
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 1.604
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.599
RAB11A RAB11A, member RAS oncogene family 1.591
MYOF myoferlin 1.581
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 1.575
POFUT2 protein O-fucosyltransferase 2 1.568
NKTR natural killer cell triggering receptor 1.559
MYL1 myosin, light chain 1, alkali; skeletal, fast 1.551
TBL1X transducin (beta)-like 1X-linked 1.547
LCMT2 leucine carboxyl methyltransferase 2 1.536
CORO7-PAM16 CORO7-PAM16 readthrough 1.534
XPO1 exportin 1 1.533
ADCY10 adenylate cyclase 10 (soluble) 1.532
IDE insulin-degrading enzyme 1.53
GABARAPL2 GABA(A) receptor-associated protein-like 2 1.528
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.525
GABARAPL1 GABA(A) receptor-associated protein like 1 1.507
DNAH8 dynein, axonemal, heavy chain 8 1.505
FMN1 formin 1 1.496
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 1.494
CYBC1 cytochrome b-245 chaperone 1 1.493
TLR2 toll-like receptor 2 1.485
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.483
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 1.477
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 1.474
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 1.46
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 1.46
HM13 histocompatibility (minor) 13 1.451
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 1.448
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 1.447
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3 1.447
RAB6A RAB6A, member RAS oncogene family 1.446
IL2 interleukin 2 1.442
TNF tumor necrosis factor 1.439
CTSC cathepsin C 1.421
CDC50B cell division cycle 50 P4-ATPase accessory subunit B 1.414
CST2 cystatin SA 1.414
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.41
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.404
EPB41 erythrocyte membrane protein band 4.1 1.401
ATF6B activating transcription factor 6 beta 1.401
TUB tubby bipartite transcription factor 1.398
ZDHHC7 zinc finger, DHHC-type containing 7 1.397
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.393
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.39
GOLGA4 golgin A4 1.385
GBP1 guanylate binding protein 1, interferon-inducible 1.383
EBNA1BP2 EBNA1 binding protein 2 1.379
SKA3 spindle and kinetochore associated complex subunit 3 1.378
CCL13 chemokine (C-C motif) ligand 13 1.378
TLR4 toll-like receptor 4 1.377
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.375
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 1.372
PALM3 paralemmin 3 1.371
FYB1 FYN binding protein 1 1.369
RHAG Rh-associated glycoprotein 1.366
SCARB1 scavenger receptor class B, member 1 1.355
COL18A1 collagen, type XVIII, alpha 1 1.341
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.341
PRAP1 proline-rich acidic protein 1 1.338
TMEM115 transmembrane protein 115 1.331
MYO1E myosin IE 1.327
MYD88 myeloid differentiation primary response 88 1.326
PLPP6 phospholipid phosphatase 6 1.321
GORASP2 golgi reassembly stacking protein 2, 55kDa 1.32
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 1.319
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 1.314
IL6 interleukin 6 1.313
PPA1 pyrophosphatase (inorganic) 1 1.307
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 1.305
ENO2 enolase 2 (gamma, neuronal) 1.298
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.288
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 1.288
ZNF160 zinc finger protein 160 1.279
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.275
STX6 syntaxin 6 1.26
RHOBTB2 Rho-related BTB domain containing 2 1.257
LCN8 lipocalin 8 1.255
SCAI suppressor of cancer cell invasion 1.254
ADSL adenylosuccinate lyase 1.243
CLTC clathrin, heavy chain (Hc) 1.241
ICAM1 intercellular adhesion molecule 1 1.24
IL17F interleukin 17F 1.238
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 1.236
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.232
SALL1 spalt-like transcription factor 1 1.228
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.228
CLTCL1 clathrin, heavy chain-like 1 1.227
ATG3 autophagy related 3 1.225
STAT1 signal transducer and activator of transcription 1, 91kDa 1.211
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 1.209
LRR1 leucine rich repeat protein 1 1.209
DERL1 derlin 1 1.209
SLC35G5 solute carrier family 35, member G5 1.207
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 1.206
SPINK1 serine peptidase inhibitor, Kazal type 1 1.205
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 1.205
TXN2 thioredoxin 2 1.2
TPPP tubulin polymerization promoting protein 1.197
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.191
SASS6 spindle assembly 6 homolog (C. elegans) 1.188
IL1B interleukin 1, beta 1.186
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 1.18
LMF1 lipase maturation factor 1 1.18
THBS1 thrombospondin 1 1.18
CTSS cathepsin S 1.18
RAB1A RAB1A, member RAS oncogene family 1.178
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 1.177
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.173
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.172
NTPCR nucleoside-triphosphatase, cancer-related 1.17
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 1.165
ENO1 enolase 1, (alpha) 1.165
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 1.16
PDE7A phosphodiesterase 7A 1.158
TMEM102 transmembrane protein 102 1.157
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 1.155
GOLPH3 golgi phosphoprotein 3 (coat-protein) 1.154
HEPH hephaestin 1.146
NEXN nexilin (F actin binding protein) 1.143
HACD1 3-hydroxyacyl-CoA dehydratase 1 1.143
H2BC21 H2B clustered histone 21 1.143
NCF4 neutrophil cytosolic factor 4, 40kDa 1.142
SARS1 seryl-tRNA synthetase 1 1.142
PLG plasminogen 1.14
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.14
SCARB2 scavenger receptor class B, member 2 1.14
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.138
CD36 CD36 molecule (thrombospondin receptor) 1.132
SARS2 seryl-tRNA synthetase 2, mitochondrial 1.131
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 1.127
PLBD2 phospholipase B domain containing 2 1.127
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.123
CAMLG calcium modulating ligand 1.121
TFRC transferrin receptor 1.115
PEG10 paternally expressed 10 1.112
MTARC1 mitochondrial amidoxime reducing component 1 1.112
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.112
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 1.103
CD81 CD81 molecule 1.1
TLN1 talin 1 1.095
OXSM 3-oxoacyl-ACP synthase, mitochondrial 1.094
MAF1 MAF1 homolog (S. cerevisiae) 1.093
PKM pyruvate kinase, muscle 1.093
NEK3 NIMA-related kinase 3 1.088
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.082
CTSB cathepsin B 1.081
TLR9 toll-like receptor 9 1.08
TUBA4A tubulin, alpha 4a 1.074
MCF2 MCF.2 cell line derived transforming sequence 1.073
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 1.07
CDC50A cell division cycle 50 P4-ATPase accessory subunit A 1.069
MYCBPAP MYCBP associated protein 1.067
GPR132 G protein-coupled receptor 132 1.065
IDO1 indoleamine 2,3-dioxygenase 1 1.058
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 1.057
IL18 interleukin 18 1.057
RTL5 retrotransposon Gag like 5 1.057
S100A9 S100 calcium binding protein A9 1.055
WDR7 WD repeat domain 7 1.054
CD40 CD40 molecule, TNF receptor superfamily member 5 1.05
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.05
TBATA thymus, brain and testes associated 1.048
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.046
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 1.042
TYMS thymidylate synthetase 1.041
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.039
ELOA elongin A 1.039
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.036
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 1.035
ZDHHC2 zinc finger, DHHC-type containing 2 1.033
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae) 1.03
DHODH dihydroorotate dehydrogenase (quinone) 1.029
MOGS mannosyl-oligosaccharide glucosidase 1.029
ATG7 autophagy related 7 1.027
UNC93B1 unc-93 homolog B1 (C. elegans) 1.027
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 1.026
RTN4IP1 reticulon 4 interacting protein 1 1.024
TGFBRAP1 transforming growth factor, beta receptor associated protein 1 1.023
IDO2 indoleamine 2,3-dioxygenase 2 1.022
SLC44A4 solute carrier family 44, member 4 1.016
LAP3 leucine aminopeptidase 3 1.015
YME1L1 YME1-like 1 ATPase 1.013
CCL2 chemokine (C-C motif) ligand 2 1.013
PPP6C protein phosphatase 6, catalytic subunit 1.013
B3GLCT beta 3-glucosyltransferase 1.007
NEK1 NIMA-related kinase 1 1.004
EEF2 eukaryotic translation elongation factor 2 1.001
SNX22 sorting nexin 22 0.999
RAB1B RAB1B, member RAS oncogene family 0.998
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.995
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.995
SCFD1 sec1 family domain containing 1 0.993
EGFR epidermal growth factor receptor 0.992
SPAG6 sperm associated antigen 6 0.988
RTL4 retrotransposon Gag like 4 0.986
EFCAB6 EF-hand calcium binding domain 6 0.985
NUCB1 nucleobindin 1 0.984
TSPYL2 TSPY-like 2 0.984
SPAG1 sperm associated antigen 1 0.983
MORC1 MORC family CW-type zinc finger 1 0.982
GYPE glycophorin E (MNS blood group) 0.981
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.98
NLRP1 NLR family, pyrin domain containing 1 0.976
DNM1L dynamin 1-like 0.974
ELAC2 elaC ribonuclease Z 2 0.974
PEG3 paternally expressed 3 0.973
HABP2 hyaluronan binding protein 2 0.972
RCC1 regulator of chromosome condensation 1 0.969
HSPA1B heat shock 70kDa protein 1B 0.962
ZNF410 zinc finger protein 410 0.961
PYDC1 PYD (pyrin domain) containing 1 0.957
GPHRA golgi pH regulator A 0.956
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.955
STX12 syntaxin 12 0.953
RAB2A RAB2A, member RAS oncogene family 0.95
TLR5 toll-like receptor 5 0.949
C3 complement component 3 0.948
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 0.947
BAG5 BCL2-associated athanogene 5 0.947
GBP2 guanylate binding protein 2, interferon-inducible 0.946
UBP1 upstream binding protein 1 (LBP-1a) 0.945
POTEF POTE ankyrin domain family, member F 0.943
TANK TRAF family member-associated NFKB activator 0.941
NEK2 NIMA-related kinase 2 0.937
TGFB1 transforming growth factor, beta 1 0.936
CNOT1 CCR4-NOT transcription complex, subunit 1 0.934
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.931
EMP1 epithelial membrane protein 1 0.931
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.929
RAB4A RAB4A, member RAS oncogene family 0.927
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.924
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.921
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 0.921
EPS15 epidermal growth factor receptor pathway substrate 15 0.92
GSTM1 glutathione S-transferase mu 1 0.92
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 0.918
TUBB4B tubulin, beta 4B class IVb 0.915
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.912
MSRB1 methionine sulfoxide reductase B1 0.912
LMO7 LIM domain 7 0.911
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.91
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 0.906
ATG12 autophagy related 12 0.903
HSPA2 heat shock 70kDa protein 2 0.903
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.902
HSPA1A heat shock 70kDa protein 1A 0.901
GLRX glutaredoxin (thioltransferase) 0.9
ATG5 autophagy related 5 0.9
CD86 CD86 molecule 0.898
THBS3 thrombospondin 3 0.897
IL15 interleukin 15 0.895
UBL4A ubiquitin-like 4A 0.894
CCL7 chemokine (C-C motif) ligand 7 0.894
USO1 USO1 vesicle transport factor 0.892
NENF neudesin neurotrophic factor 0.89
MDP1 magnesium-dependent phosphatase 1 0.89
APEH acylaminoacyl-peptide hydrolase 0.889
MAPK1 mitogen-activated protein kinase 1 0.888
BFSP2 beaded filament structural protein 2, phakinin 0.888
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.886
CFP complement factor properdin 0.886
PARK7 parkinson protein 7 0.886
PMCH pro-melanin-concentrating hormone 0.885
ANK1 ankyrin 1, erythrocytic 0.882
ICMT isoprenylcysteine carboxyl methyltransferase 0.88
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.88
GFM1 G elongation factor, mitochondrial 1 0.879
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.876
PIGW phosphatidylinositol glycan anchor biosynthesis, class W 0.873
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.871
CD40LG CD40 ligand 0.866
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.865
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.864
PROCR protein C receptor, endothelial 0.863
KAT2B K(lysine) acetyltransferase 2B 0.861
SPON1 spondin 1, extracellular matrix protein 0.859
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.859
EMG1 EMG1 N1-specific pseudouridine methyltransferase 0.855
LOC102724197 inactive gamma-glutamyltranspeptidase 2-like 0.85
RAB18 RAB18, member RAS oncogene family 0.848
CXCL8 chemokine (C-X-C motif) ligand 8 0.848
RTL8C retrotransposon Gag like 8C 0.846
CCNL2 cyclin L2 0.845
SOS1 son of sevenless homolog 1 (Drosophila) 0.844
PLK1 polo-like kinase 1 0.843
IRGM immunity-related GTPase family, M 0.842
EGR2 early growth response 2 0.841
CAPN1 calpain 1, (mu/I) large subunit 0.84
KAT2A K(lysine) acetyltransferase 2A 0.835
FPGT fucose-1-phosphate guanylyltransferase 0.834
ARF1 ADP-ribosylation factor 1 0.833
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.833
FDXR ferredoxin reductase 0.833
STX5 syntaxin 5 0.831
ULK1 unc-51 like autophagy activating kinase 1 0.831
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.83
IL1A interleukin 1, alpha 0.827
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) 0.827
ASCL4 achaete-scute family bHLH transcription factor 4 0.826
PPT1 palmitoyl-protein thioesterase 1 0.824
IL5 interleukin 5 0.822
GAK cyclin G associated kinase 0.822
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 0.818
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.817
HLA-A major histocompatibility complex, class I, A 0.817
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 0.816
ZSCAN32 zinc finger and SCAN domain containing 32 0.809
SEC62 SEC62 homolog (S. cerevisiae) 0.808
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.807
CLSTN1 calsyntenin 1 0.805
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.801
HLA-B major histocompatibility complex, class I, B 0.8
MRPL23 mitochondrial ribosomal protein L23 0.798
GBA1 glucosylceramidase beta 1 0.797
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.795
RAP1B RAP1B, member of RAS oncogene family 0.794
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.793
TLR3 toll-like receptor 3 0.793
CYTH1 cytohesin 1 0.793
INS insulin 0.791
AOPEP aminopeptidase O (putative) 0.789
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.787
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.787
SLC9C1 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 0.782
SP3 Sp3 transcription factor 0.782
SRI sorcin 0.781
AKAP4 A kinase (PRKA) anchor protein 4 0.779
LOX lysyl oxidase 0.779
TBCE tubulin folding cofactor E 0.778
CLASP1 cytoplasmic linker associated protein 1 0.776
STX16 syntaxin 16 0.776
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.776
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.776
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 0.775
TP53 tumor protein p53 0.773
ZDHHC14 zinc finger, DHHC-type containing 14 0.772
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.771
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.77
ATG14 autophagy related 14 0.767
ARHGAP9 Rho GTPase activating protein 9 0.767
SKP1 S-phase kinase-associated protein 1 0.767
AGBL2 ATP/GTP binding protein-like 2 0.765
OTOF otoferlin 0.763
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.76
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.759
IFNB1 interferon, beta 1, fibroblast 0.755
MAPK14 mitogen-activated protein kinase 14 0.755
LOC107987479 cytochrome P450 2D6 0.754
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.753
IFNA1 interferon, alpha 1 0.752
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 0.752
CCL22 chemokine (C-C motif) ligand 22 0.752
MYO5C myosin VC 0.751
SNRPF small nuclear ribonucleoprotein polypeptide F 0.75
CXCL10 chemokine (C-X-C motif) ligand 10 0.746
MUC17 mucin 17, cell surface associated 0.746
DEK DEK proto-oncogene 0.745
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.744
MYO5A myosin VA (heavy chain 12, myoxin) 0.744
LAMP1 lysosomal-associated membrane protein 1 0.744
EPHA2 EPH receptor A2 0.743
DNPEP aspartyl aminopeptidase 0.74
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.74
PDCD5 programmed cell death 5 0.74
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 0.739
MUC4 mucin 4, cell surface associated 0.739
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.738
CLK3 CDC-like kinase 3 0.734
CEMP1 cementum protein 1 0.733
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.733
IRGC immunity-related GTPase family, cinema 0.732
STOM stomatin 0.732
TLR7 toll-like receptor 7 0.732
FHIP1B FHF complex subunit HOOK interacting protein 1B 0.732
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.728
BET1 Bet1 golgi vesicular membrane trafficking protein 0.728
NLRP2 NLR family, pyrin domain containing 2 0.727
OSBPL2 oxysterol binding protein-like 2 0.726
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0.726
TUBB6 tubulin, beta 6 class V 0.724
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.724
RB1CC1 RB1-inducible coiled-coil 1 0.723
SYT5 synaptotagmin V 0.721
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.721
MOSPD2 motile sperm domain containing 2 0.718
DPYSL2 dihydropyrimidinase-like 2 0.718
AGFG1 ArfGAP with FG repeats 1 0.717
MYO5B myosin VB 0.716
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.716
PPY pancreatic polypeptide 0.715
SRPK1 SRSF protein kinase 1 0.714
DERA deoxyribose-phosphate aldolase (putative) 0.714
PI3 peptidase inhibitor 3, skin-derived 0.713
PMPCA peptidase (mitochondrial processing) alpha 0.713
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.713
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 0.711
TPST1 tyrosylprotein sulfotransferase 1 0.709
CRMP1 collapsin response mediator protein 1 0.708
TXNDC9 thioredoxin domain containing 9 0.706
SRP72 signal recognition particle 72kDa 0.704
CISH cytokine inducible SH2-containing protein 0.703
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.703
PHGDH phosphoglycerate dehydrogenase 0.702
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 0.702
CRPPA CDP-L-ribitol pyrophosphorylase A 0.701
PHF12 PHD finger protein 12 0.701
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 0.7
GAPVD1 GTPase activating protein and VPS9 domains 1 0.7
RAP1A RAP1A, member of RAS oncogene family 0.697
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.697
DIXDC1 DIX domain containing 1 0.697
H2BC3 H2B clustered histone 3 0.694
H2BC11 H2B clustered histone 11 0.694
S100A11 S100 calcium binding protein A11 0.691
CD80 CD80 molecule 0.691
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.69
BICD2 bicaudal D homolog 2 (Drosophila) 0.689
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 0.689
H3C7 H3 clustered histone 7 0.688
H3-3B H3.3 histone B 0.686
HELQ helicase, POLQ-like 0.685
FMN2 formin 2 0.684
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.682
BECN1 beclin 1, autophagy related 0.682
TEX101 testis expressed 101 0.681
CCL5 chemokine (C-C motif) ligand 5 0.676
H3-7 H3.7 histone (putative) 0.676
H3C13 H3 clustered histone 13 0.675
H3-5 H3.5 histone 0.675
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.675
H3-4 H3.4 histone, cluster member 0.674
SNRPA small nuclear ribonucleoprotein polypeptide A 0.673
PRDX2 peroxiredoxin 2 0.673
SOCS1 suppressor of cytokine signaling 1 0.672
CDC42 cell division cycle 42 0.671
DHPS deoxyhypusine synthase 0.671
RYR1 ryanodine receptor 1 (skeletal) 0.671
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.67
SELE selectin E 0.668
CCDC25 coiled-coil domain containing 25 0.668
GPR119 G protein-coupled receptor 119 0.667
PDE5A phosphodiesterase 5A, cGMP-specific 0.667
PGAP1 post-GPI attachment to proteins 1 0.667
SNAP91 synaptosomal-associated protein, 91kDa 0.666
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.665
EXOC8 exocyst complex component 8 0.664
SERP1 stress-associated endoplasmic reticulum protein 1 0.662
ZDHHC4 zinc finger, DHHC-type containing 4 0.657
GP2 glycoprotein 2 (zymogen granule membrane) 0.657
FKBP1A FK506 binding protein 1A, 12kDa 0.657
ADD1 adducin 1 (alpha) 0.657
TPT1 tumor protein, translationally-controlled 1 0.655
ZDHHC1 zinc finger, DHHC-type containing 1 0.655
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 0.654
HDAC3 histone deacetylase 3 0.651
RTL3 retrotransposon Gag like 3 0.651
GUF1 GUF1 GTPase homolog (S. cerevisiae) 0.649
TUBA3D tubulin, alpha 3d 0.649
CHMP2A charged multivesicular body protein 2A 0.648
COCH cochlin 0.647
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.647
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 0.646
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.646
C4B complement component 4B (Chido blood group) 0.646
IL13 interleukin 13 0.644
PRADC1 protease-associated domain containing 1 0.643
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 0.643
RPL36 ribosomal protein L36 0.643
ACSS1 acyl-CoA synthetase short-chain family member 1 0.642
NLRC5 NLR family, CARD domain containing 5 0.641
CD200 CD200 molecule 0.641
DOC2A double C2-like domains, alpha 0.641
GNPDA1 glucosamine-6-phosphate deaminase 1 0.64
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.639
TUBB2A tubulin, beta 2A class IIa 0.639
DYNLL1 dynein, light chain, LC8-type 1 0.638
DYNLL2 dynein, light chain, LC8-type 2 0.636
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 0.635
H2AC20 H2A clustered histone 20 0.634
ACAA1 acetyl-CoA acyltransferase 1 0.634
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.634
IWS1 IWS1 homolog (S. cerevisiae) 0.634
NEMF nuclear export mediator factor 0.633
TUBB8 tubulin, beta 8 class VIII 0.632
PIGK phosphatidylinositol glycan anchor biosynthesis, class K 0.632
H2AC19 H2A clustered histone 19 0.632
EXOC7 exocyst complex component 7 0.631
CC2D1A coiled-coil and C2 domain containing 1A 0.631
CCL24 chemokine (C-C motif) ligand 24 0.628
SELL selectin L 0.628
TTC7A tetratricopeptide repeat domain 7A 0.628
LINC02762 long intergenic non-protein coding RNA 2762 0.626
TLK2 tousled-like kinase 2 0.626
ISY1-RAB43 ISY1-RAB43 readthrough 0.624
DEGS1 delta(4)-desaturase, sphingolipid 1 0.623
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.622
SART1 squamous cell carcinoma antigen recognized by T cells 0.621
SEPTIN8 septin 8 0.621
FASLG Fas ligand (TNF superfamily, member 6) 0.621
MRAS muscle RAS oncogene homolog 0.616
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.615
TLR1 toll-like receptor 1 0.612
SEC24A SEC24 family member A 0.612
ATG10 autophagy related 10 0.609
MCM9 minichromosome maintenance complex component 9 0.609
GLRX3 glutaredoxin 3 0.609
SLC38A3 solute carrier family 38, member 3 0.608
TUBB4A tubulin, beta 4A class IVa 0.607
GDI1 GDP dissociation inhibitor 1 0.606
PDS5B PDS5 cohesin associated factor B 0.606
GDPGP1 GDP-D-glucose phosphorylase 1 0.606
H4C7 H4 clustered histone 7 0.605
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.605
CLIP1 CAP-GLY domain containing linker protein 1 0.604
UNK unkempt family zinc finger 0.603
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 0.603
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.603
REM1 RAS (RAD and GEM)-like GTP-binding 1 0.603
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.602
ADD3 adducin 3 (gamma) 0.602
FN1 fibronectin 1 0.602
AMPH amphiphysin 0.602
SLC35B1 solute carrier family 35, member B1 0.6
NLRP8 NLR family, pyrin domain containing 8 0.6
ADD2 adducin 2 (beta) 0.6
RYR2 ryanodine receptor 2 (cardiac) 0.599
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.599
NEBL nebulette 0.597
FGD4 FYVE, RhoGEF and PH domain containing 4 0.597
RABIF RAB interacting factor 0.597
MRC2 mannose receptor, C type 2 0.596
FDPS farnesyl diphosphate synthase 0.596
ALPP alkaline phosphatase, placental 0.594
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 0.591
E2F4 E2F transcription factor 4, p107/p130-binding 0.591
CHI3L2 chitinase 3-like 2 0.589
SUMO4 small ubiquitin-like modifier 4 0.589
SORCS3 sortilin-related VPS10 domain containing receptor 3 0.589
TUBA3E tubulin, alpha 3e 0.588
IZUMO1 izumo sperm-egg fusion 1 0.588
KNCN kinocilin 0.587
ZDHHC3 zinc finger, DHHC-type containing 3 0.587
H4C15 H4 clustered histone 15 0.587
TUBA1C tubulin, alpha 1c 0.587
MFSD2B major facilitator superfamily domain containing 2B 0.586
DOC2B double C2-like domains, beta 0.586
IGF2 insulin-like growth factor 2 0.585
TUBAL3 tubulin, alpha-like 3 0.585
ANKFY1 ankyrin repeat and FYVE domain containing 1 0.585
ZNF232 zinc finger protein 232 0.584
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.584
EEF1G eukaryotic translation elongation factor 1 gamma 0.583
HSPB3 heat shock 27kDa protein 3 0.583
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.582
ADI1 acireductone dioxygenase 1 0.581
ITGB1BP1 integrin beta 1 binding protein 1 0.58
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 0.58
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.579
SEL1L2 sel-1 suppressor of lin-12-like 2 (C. elegans) 0.576
TUBB tubulin, beta class I 0.576
C4A complement component 4A (Rodgers blood group) 0.574
TXK TXK tyrosine kinase 0.573
HACD4 3-hydroxyacyl-CoA dehydratase 4 0.572
RRBP1 ribosome binding protein 1 0.572
GDI2 GDP dissociation inhibitor 2 0.572
FES FES proto-oncogene, tyrosine kinase 0.571
H2BK1 H2B.K variant histone 1 0.57
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.569
GLB1 galactosidase, beta 1 0.569
JUN jun proto-oncogene 0.569
H2BW2 H2B.W histone 2 0.568
H2BW1 H2B.W histone 1 0.568
H2BC12L H2B clustered histone 12 like 0.568
GGT1 gamma-glutamyltransferase 1 0.568
ZNF273 zinc finger protein 273 0.567
GPR180 G protein-coupled receptor 180 0.567
H2BC13 H2B clustered histone 13 0.566
H2BC18 H2B clustered histone 18 0.565
TBX21 T-box 21 0.565
XCL1 chemokine (C motif) ligand 1 0.565
H2BC26 H2B clustered histone 26 0.564
H2BC17 H2B clustered histone 17 0.564
H2BC14 H2B clustered histone 14 0.564
H2BC9 H2B clustered histone 9 0.564
NELFE negative elongation factor complex member E 0.564
MARS1 methionyl-tRNA synthetase 1 0.563
UBE2F ubiquitin-conjugating enzyme E2F (putative) 0.563
SRP19 signal recognition particle 19kDa 0.561
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.561
PSCA prostate stem cell antigen 0.561
FPGS folylpolyglutamate synthase 0.56
H2BC15 H2B clustered histone 15 0.56
MYO1D myosin ID 0.559
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.557
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.557
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.556
H2BC12 H2B clustered histone 12 0.555
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.554
ELANE elastase, neutrophil expressed 0.554
SEC13 SEC13 homolog (S. cerevisiae) 0.553
IRF1 interferon regulatory factor 1 0.552
SOCS3 suppressor of cytokine signaling 3 0.551
H2BC4 H2B clustered histone 4 0.548
FKBP1C FK506 binding protein 1C 0.548
H2BC1 H2B clustered histone 1 0.548
FGB fibrinogen beta chain 0.548
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.546
SEC24B SEC24 family member B 0.545
PRKCA protein kinase C, alpha 0.544
FAIM Fas apoptotic inhibitory molecule 0.544
H2BC5 H2B clustered histone 5 0.544
ACSS2 acyl-CoA synthetase short-chain family member 2 0.543
LGALS4 lectin, galactoside-binding, soluble, 4 0.543
VCAM1 vascular cell adhesion molecule 1 0.542
ELOC elongin C 0.542
TCF15 transcription factor 15 (basic helix-loop-helix) 0.541
CXCL9 chemokine (C-X-C motif) ligand 9 0.54
PTS 6-pyruvoyltetrahydropterin synthase 0.54
GABARAP GABA(A) receptor-associated protein 0.54
MBL2 mannose-binding lectin (protein C) 2, soluble 0.539
STAT2 signal transducer and activator of transcription 2, 113kDa 0.539
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.538
CCL17 chemokine (C-C motif) ligand 17 0.538
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.538
TMED3 transmembrane emp24 protein transport domain containing 3 0.538
TUBA8 tubulin, alpha 8 0.537
RCC1L RCC1 like 0.537
EXOSC8 exosome component 8 0.534
BIN1 bridging integrator 1 0.534
TUBB2B tubulin, beta 2B class IIb 0.532
ZNRD2 zinc ribbon domain containing 2 0.531
DNM2 dynamin 2 0.529
HIP1R huntingtin interacting protein 1 related 0.528
PGK1 phosphoglycerate kinase 1 0.528
IL22 interleukin 22 0.528
EMC1 ER membrane protein complex subunit 1 0.528
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 0.528
TUBB3 tubulin, beta 3 class III 0.527
PRSS57 protease, serine, 57 0.527
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.527
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.527
CCR7 chemokine (C-C motif) receptor 7 0.524
NANOS2 nanos homolog 2 (Drosophila) 0.524
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.524
CYTH3 cytohesin 3 0.523
DPP3 dipeptidyl-peptidase 3 0.523
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.523
NOX5 NADPH oxidase, EF-hand calcium binding domain 5 0.523
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 0.522
HLA-E major histocompatibility complex, class I, E 0.522
SP9 Sp9 transcription factor 0.521
VCX variable charge, X-linked 0.52
CEP250 centrosomal protein 250kDa 0.515
MMP10 matrix metallopeptidase 10 0.515
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.515
EIF1B eukaryotic translation initiation factor 1B 0.513
MCMBP minichromosome maintenance complex binding protein 0.513
PIGL phosphatidylinositol glycan anchor biosynthesis, class L 0.512
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.512
TPI1 triosephosphate isomerase 1 0.512
THBS4 thrombospondin 4 0.512
CCL20 chemokine (C-C motif) ligand 20 0.511
SEC11C SEC11 homolog C (S. cerevisiae) 0.511
NDC80 NDC80 kinetochore complex component 0.511
GSTA3 glutathione S-transferase alpha 3 0.511
PMVK phosphomevalonate kinase 0.51
FOXP3 forkhead box P3 0.508
TMED2 transmembrane emp24 domain trafficking protein 2 0.505
CD274 CD274 molecule 0.505
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.505
MYB v-myb avian myeloblastosis viral oncogene homolog 0.505
MON1A MON1 secretory trafficking family member A 0.504
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.503
SNAP23 synaptosomal-associated protein, 23kDa 0.503
PLSCR4 phospholipid scramblase 4 0.502
PHEX phosphate regulating endopeptidase homolog, X-linked 0.502
TLR6 toll-like receptor 6 0.502
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.501
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.501
SRP9 signal recognition particle 9kDa 0.5