Microspike Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A dynamic, actin-rich projection extending from the surface of a migrating animal cell. (Gene Ontology, GO_0044393)
External Link http://amigo.geneontology.org/amigo/term/GO:0044393
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Genes

606 proteins co-occuring with the Microspike cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FSCN1 fascin actin-bundling protein 1 2.91
CDC42 cell division cycle 42 2.733
WAS Wiskott-Aldrich syndrome 2.352
WASL Wiskott-Aldrich syndrome-like 2.339
VASP vasodilator-stimulated phosphoprotein 2.315
RHOA ras homolog family member A 2.286
FGD4 FYVE, RhoGEF and PH domain containing 4 2.229
BAIAP2 BAI1-associated protein 2 2.223
VCL vinculin 2.149
EZR ezrin 2.085
CTTN cortactin 2.076
HCLS1 hematopoietic cell-specific Lyn substrate 1 2.07
PFN1 profilin 1 2.057
MSN moesin 2.048
PFN4 profilin family, member 4 2.027
FSCN3 fascin actin-bundling protein 3, testicular 2.025
PFN3 profilin 3 2.017
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 2.009
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.006
WASF2 WAS protein family, member 2 1.997
FN1 fibronectin 1 1.98
MTSS1 metastasis suppressor 1 1.971
RDX radixin 1.942
CFL2 cofilin 2 (muscle) 1.94
TLN2 talin 2 1.938
FSCN2 fascin actin-bundling protein 2, retinal 1.929
TLN1 talin 1 1.926
MYH14 myosin, heavy chain 14, non-muscle 1.903
DIAPH3 diaphanous-related formin 3 1.888
FMNL2 formin-like 2 1.859
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.858
EVL Enah/Vasp-like 1.838
FMNL3 formin-like 3 1.81
MCF2 MCF.2 cell line derived transforming sequence 1.794
WASF1 WAS protein family, member 1 1.779
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 1.76
PLEK2 pleckstrin 2 1.704
FLNA filamin A, alpha 1.704
PLEK pleckstrin 1.694
MYO10 myosin X 1.689
FNBP1 formin binding protein 1 1.689
RHOF ras homolog family member F (in filopodia) 1.687
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 1.687
FLNB filamin B, beta 1.654
PTK2 protein tyrosine kinase 2 1.637
IQGAP1 IQ motif containing GTPase activating protein 1 1.627
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.614
TRIP10 thyroid hormone receptor interactor 10 1.608
RHOC ras homolog family member C 1.597
EGF epidermal growth factor 1.595
ZYX zyxin 1.593
EPS8 epidermal growth factor receptor pathway substrate 8 1.583
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 1.58
FMNL1 formin-like 1 1.572
FLNC filamin C, gamma 1.571
ABI1 abl-interactor 1 1.552
FGD1 FYVE, RhoGEF and PH domain containing 1 1.545
BAIAP2L1 BAI1-associated protein 2-like 1 1.531
RABIF RAB interacting factor 1.531
CRMP1 collapsin response mediator protein 1 1.516
RHOB ras homolog family member B 1.514
PLS3 plastin 3 1.507
EPB41 erythrocyte membrane protein band 4.1 1.497
NEXN nexilin (F actin binding protein) 1.492
TOX4 TOX high mobility group box family member 4 1.482
NCK1 NCK adaptor protein 1 1.47
LIMK1 LIM domain kinase 1 1.467
NGF nerve growth factor (beta polypeptide) 1.466
RTKN rhotekin 1.462
CDH17 cadherin 17, LI cadherin (liver-intestine) 1.46
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 1.455
RHOV ras homolog family member V 1.449
ABI2 abl-interactor 2 1.44
THBS1 thrombospondin 1 1.435
TIAM1 T-cell lymphoma invasion and metastasis 1 1.429
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 1.426
DBN1 drebrin 1 1.418
VAV1 vav 1 guanine nucleotide exchange factor 1.417
AMPH amphiphysin 1.416
RHOD ras homolog family member D 1.411
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 1.389
CHN1 chimerin 1 1.388
GSN gelsolin 1.385
SCIN scinderin 1.385
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.381
BIN1 bridging integrator 1 1.365
SCRN3 secernin 3 1.364
BAIAP2L2 BAI1-associated protein 2-like 2 1.35
STRIP2 striatin interacting protein 2 1.35
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.346
PALM paralemmin 1.339
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.331
RHOG ras homolog family member G 1.328
WASF3 WAS protein family, member 3 1.325
SLCO6A1 solute carrier organic anion transporter family, member 6A1 1.324
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 1.323
GRB2 growth factor receptor-bound protein 2 1.302
FGD3 FYVE, RhoGEF and PH domain containing 3 1.298
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 1.298
VILL villin-like 1.271
STRIP1 striatin interacting protein 1 1.27
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 1.269
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 1.265
FBF1 Fas (TNFRSF6) binding factor 1 1.262
KLHDC1 kelch domain containing 1 1.255
VTN vitronectin 1.248
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 1.248
FNBP1L formin binding protein 1-like 1.246
SYNGAP1 synaptic Ras GTPase activating protein 1 1.242
BCAR1 breast cancer anti-estrogen resistance 1 1.238
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 1.233
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.232
CYFIP2 cytoplasmic FMR1 interacting protein 2 1.231
ENAH enabled homolog (Drosophila) 1.231
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.226
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 1.223
KNG1 kininogen 1 1.218
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 1.217
SH3PXD2A SH3 and PX domains 2A 1.217
CLSTN1 calsyntenin 1 1.215
SDC2 syndecan 2 1.215
DOCK1 dedicator of cytokinesis 1 1.213
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.211
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.21
WIPF1 WAS/WASL interacting protein family, member 1 1.202
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.198
FES FES proto-oncogene, tyrosine kinase 1.188
PLS1 plastin 1 1.187
EFHD2 EF-hand domain family, member D2 1.18
MARCKS myristoylated alanine-rich protein kinase C substrate 1.178
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.177
CARMIL1 capping protein regulator and myosin 1 linker 1 1.176
RHOU ras homolog family member U 1.176
ACTN3 actinin, alpha 3 (gene/pseudogene) 1.171
VAV2 vav 2 guanine nucleotide exchange factor 1.17
PKN2 protein kinase N2 1.166
PXDNL peroxidasin-like 1.165
PXDN peroxidasin 1.164
VAV3 vav 3 guanine nucleotide exchange factor 1.162
ARHGAP35 Rho GTPase activating protein 35 1.159
C1QTNF8 C1q and tumor necrosis factor related protein 8 1.158
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 1.155
NHSL1 NHS-like 1 1.152
ARHGAP1 Rho GTPase activating protein 1 1.15
CD44 CD44 molecule (Indian blood group) 1.149
NF2 neurofibromin 2 (merlin) 1.147
DNM2 dynamin 2 1.138
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.137
ITSN2 intersectin 2 1.131
RHOQ ras homolog family member Q 1.129
CALD1 caldesmon 1 1.128
FBXL18 F-box and leucine-rich repeat protein 18 1.124
RHOH ras homolog family member H 1.12
GAP43 growth associated protein 43 1.119
MRAS muscle RAS oncogene homolog 1.115
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.115
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1.114
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 1.112
CAPZA1 capping protein (actin filament) muscle Z-line, alpha 1 1.112
LGALS4 lectin, galactoside-binding, soluble, 4 1.107
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 1.106
MMP9 matrix metallopeptidase 9 1.102
SYNE2 spectrin repeat containing, nuclear envelope 2 1.1
EGFR epidermal growth factor receptor 1.091
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 1.091
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 1.086
WHAMM WAS protein homolog associated with actin, golgi membranes and microtubules 1.075
CSPG4 chondroitin sulfate proteoglycan 4 1.075
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 1.073
PLPPR5 phospholipid phosphatase related 5 1.061
WIPF2 WAS/WASL interacting protein family, member 2 1.061
MUC4 mucin 4, cell surface associated 1.059
FGF13 fibroblast growth factor 13 1.056
RAP1B RAP1B, member of RAS oncogene family 1.053
ESPN espin 1.049
MMP2 matrix metallopeptidase 2 1.048
CALM3 calmodulin 3 (phosphorylase kinase, delta) 1.046
TMIGD1 transmembrane and immunoglobulin domain containing 1 1.043
EPHA1 EPH receptor A1 1.037
NCK2 NCK adaptor protein 2 1.034
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.033
JUN jun proto-oncogene 1.031
ITSN1 intersectin 1 (SH3 domain protein) 1.027
RND3 Rho family GTPase 3 1.026
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1.025
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 1.024
IGF1 insulin-like growth factor 1 (somatomedin C) 1.023
CAPZB capping protein (actin filament) muscle Z-line, beta 1.022
TWF2 twinfilin actin binding protein 2 1.018
FYN FYN proto-oncogene, Src family tyrosine kinase 1.018
NCKAP1L NCK-associated protein 1-like 1.013
FCHSD2 FCH and double SH3 domains 2 1.004
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.002
TGFB1 transforming growth factor, beta 1 1.0
TMOD4 tropomodulin 4 (muscle) 0.999
LGALS8 lectin, galactoside-binding, soluble, 8 0.994
ARHGAP33 Rho GTPase activating protein 33 0.993
MAPK3 mitogen-activated protein kinase 3 0.991
NTN1 netrin 1 0.989
LIMA1 LIM domain and actin binding 1 0.981
ARF6 ADP-ribosylation factor 6 0.979
RAB35 RAB35, member RAS oncogene family 0.979
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.976
MYO1E myosin IE 0.972
CSK c-src tyrosine kinase 0.969
PTK2B protein tyrosine kinase 2 beta 0.964
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.961
JMY junction mediating and regulatory protein, p53 cofactor 0.961
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.958
ILK integrin-linked kinase 0.957
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.956
NRBP1 nuclear receptor binding protein 1 0.956
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit 0.955
DAAM1 dishevelled associated activator of morphogenesis 1 0.95
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.946
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.944
INSR insulin receptor 0.944
MTSS2 MTSS I-BAR domain containing 2 0.943
PTGFRN prostaglandin F2 receptor inhibitor 0.941
PALLD palladin, cytoskeletal associated protein 0.939
PKP4 plakophilin 4 0.934
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25 0.932
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.932
TMOD3 tropomodulin 3 (ubiquitous) 0.93
EHD2 EH-domain containing 2 0.928
ACTN1 actinin, alpha 1 0.927
PIEZO1 piezo-type mechanosensitive ion channel component 1 0.92
MYO5A myosin VA (heavy chain 12, myoxin) 0.917
IGF1R insulin-like growth factor 1 receptor 0.91
FCHO2 FCH domain only 2 0.91
SNAI1 snail family zinc finger 1 0.909
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.909
ERBB2 erb-b2 receptor tyrosine kinase 2 0.909
COBL cordon-bleu WH2 repeat protein 0.908
TNK2 tyrosine kinase, non-receptor, 2 0.906
FHOD1 formin homology 2 domain containing 1 0.906
MYH10 myosin, heavy chain 10, non-muscle 0.906
CALML6 calmodulin-like 6 0.903
CALML4 calmodulin-like 4 0.903
CALML3 calmodulin-like 3 0.902
CTNND1 catenin (cadherin-associated protein), delta 1 0.902
CALML5 calmodulin-like 5 0.902
WSB1 WD repeat and SOCS box containing 1 0.9
SPEF1 sperm flagellar 1 0.9
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.894
LIMK2 LIM domain kinase 2 0.894
MAP2K1 mitogen-activated protein kinase kinase 1 0.886
SNX9 sorting nexin 9 0.886
EFNB3 ephrin-B3 0.885
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 0.885
NAA80 N-alpha-acetyltransferase 80, NatH catalytic subunit 0.879
DOK2 docking protein 2, 56kDa 0.879
RAP1GAP RAP1 GTPase activating protein 0.878
EFNB1 ephrin-B1 0.875
ECT2 epithelial cell transforming 2 0.874
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.873
ITGA8 integrin, alpha 8 0.871
FGF18 fibroblast growth factor 18 0.87
UBTD1 ubiquitin domain containing 1 0.869
INS insulin 0.869
TNF tumor necrosis factor 0.868
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 0.868
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.868
TMOD1 tropomodulin 1 0.866
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.865
KLHDC2 kelch domain containing 2 0.864
CLIP1 CAP-GLY domain containing linker protein 1 0.864
TJP1 tight junction protein 1 0.862
TMOD2 tropomodulin 2 (neuronal) 0.854
PHPT1 phosphohistidine phosphatase 1 0.854
TP53 tumor protein p53 0.854
SDC3 syndecan 3 0.853
CDH5 cadherin 5, type 2 (vascular endothelium) 0.852
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.852
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.851
RNF113B ring finger protein 113B 0.85
FGF22 fibroblast growth factor 22 0.849
FGF16 fibroblast growth factor 16 0.848
FGF6 fibroblast growth factor 6 0.848
MYO1B myosin IB 0.848
KLHL31 kelch-like family member 31 0.847
FGF8 fibroblast growth factor 8 (androgen-induced) 0.846
FGF20 fibroblast growth factor 20 0.845
MACF1 microtubule-actin crosslinking factor 1 0.844
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.843
SRRD SRR1 domain containing 0.842
FGF17 fibroblast growth factor 17 0.842
ACTN2 actinin, alpha 2 0.841
TNS1 tensin 1 0.841
FGF3 fibroblast growth factor 3 0.84
EHD3 EH-domain containing 3 0.839
PLAUR plasminogen activator, urokinase receptor 0.838
FGF5 fibroblast growth factor 5 0.837
SOS1 son of sevenless homolog 1 (Drosophila) 0.836
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.835
IVNS1ABP influenza virus NS1A binding protein 0.835
WTIP Wilms tumor 1 interacting protein 0.833
FGF9 fibroblast growth factor 9 0.83
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.829
MYO1A myosin IA 0.828
PLEC plectin 0.828
ZNF500 zinc finger protein 500 0.827
FGF7 fibroblast growth factor 7 0.824
CMIP c-Maf inducing protein 0.822
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma 0.818
FGF4 fibroblast growth factor 4 0.818
CAV1 caveolin 1, caveolae protein, 22kDa 0.817
ARHGAP6 Rho GTPase activating protein 6 0.817
NOSTRIN nitric oxide synthase trafficking 0.816
FGF10 fibroblast growth factor 10 0.815
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.814
RNF151 ring finger protein 151 0.814
LATS1 large tumor suppressor kinase 1 0.812
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 0.811
ACTA1 actin, alpha 1, skeletal muscle 0.809
PLAU plasminogen activator, urokinase 0.807
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 0.803
IL1B interleukin 1, beta 0.802
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.799
IGSF8 immunoglobulin superfamily, member 8 0.796
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.795
ICAM1 intercellular adhesion molecule 1 0.795
ICAM2 intercellular adhesion molecule 2 0.795
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 0.794
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.792
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.791
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.788
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.787
THNSL1 threonine synthase-like 1 (S. cerevisiae) 0.786
LIMD1 LIM domains containing 1 0.783
CDK5 cyclin-dependent kinase 5 0.781
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.781
MTPN myotrophin 0.779
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.777
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.776
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.773
CXCL12 chemokine (C-X-C motif) ligand 12 0.772
EIF3A eukaryotic translation initiation factor 3, subunit A 0.77
IQGAP2 IQ motif containing GTPase activating protein 2 0.77
EPS15 epidermal growth factor receptor pathway substrate 15 0.767
TRIM74 tripartite motif containing 74 0.764
PRKCQ protein kinase C, theta 0.763
STARD13 StAR-related lipid transfer (START) domain containing 13 0.758
MYLK myosin light chain kinase 0.756
DYDC1 DPY30 domain containing 1 0.754
BDNF brain-derived neurotrophic factor 0.751
RFPL3 ret finger protein-like 3 0.751
CBLL2 Cbl proto-oncogene like 2 0.748
CORO7-PAM16 CORO7-PAM16 readthrough 0.746
RFPL2 ret finger protein-like 2 0.745
NES nestin 0.745
CSRP2 cysteine and glycine-rich protein 2 0.744
NGFR nerve growth factor receptor 0.737
MAGEH1 melanoma antigen family H1 0.735
PDPN podoplanin 0.732
WDSUB1 WD repeat, sterile alpha motif and U-box domain containing 1 0.731
LGALS3 lectin, galactoside-binding, soluble, 3 0.731
ARFIP2 ADP-ribosylation factor interacting protein 2 0.73
ARHGAP18 Rho GTPase activating protein 18 0.73
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.729
SDC1 syndecan 1 0.724
DYDC2 DPY30 domain containing 2 0.723
MARCHF3 membrane associated ring-CH-type finger 3 0.721
VEGFD vascular endothelial growth factor D 0.72
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.716
PROM1 prominin 1 0.714
SNAI2 snail family zinc finger 2 0.71
RNF215 ring finger protein 215 0.71
TNS4 tensin 4 0.707
GPR150 G protein-coupled receptor 150 0.705
ARHGAP40 Rho GTPase activating protein 40 0.703
NCKAP1 NCK-associated protein 1 0.703
RAB11A RAB11A, member RAS oncogene family 0.701
ESR1 estrogen receptor 1 0.7
CYFIP1 cytoplasmic FMR1 interacting protein 1 0.698
VCAM1 vascular cell adhesion molecule 1 0.697
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.696
ARF3 ADP-ribosylation factor 3 0.695
STK24 serine/threonine kinase 24 0.695
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.695
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.694
TNS2 tensin 2 0.693
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.693
LAMA4 laminin, alpha 4 0.692
KDR kinase insert domain receptor 0.691
ARHGAP17 Rho GTPase activating protein 17 0.69
RAB5A RAB5A, member RAS oncogene family 0.688
GSK3B glycogen synthase kinase 3 beta 0.687
SNX18 sorting nexin 18 0.685
ZEB1 zinc finger E-box binding homeobox 1 0.685
SOS2 son of sevenless homolog 2 (Drosophila) 0.685
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.684
LRSAM1 leucine rich repeat and sterile alpha motif containing 1 0.683
RLN2 relaxin 2 0.682
GFAP glial fibrillary acidic protein 0.682
GTPBP4 GTP binding protein 4 0.682
PTEN phosphatase and tensin homolog 0.681
EFNB2 ephrin-B2 0.679
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.677
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 0.677
DPYSL2 dihydropyrimidinase-like 2 0.676
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.675
CD28 CD28 molecule 0.673
ARF1 ADP-ribosylation factor 1 0.671
PELP1 proline, glutamate and leucine rich protein 1 0.666
PRKACG protein kinase, cAMP-dependent, catalytic, gamma 0.664
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.663
IL6 interleukin 6 0.662
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.662
AKAP5 A kinase (PRKA) anchor protein 5 0.661
ZNF710 zinc finger protein 710 0.66
PRKCA protein kinase C, alpha 0.66
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.659
SPNS1 spinster homolog 1 (Drosophila) 0.656
DMTN dematin actin binding protein 0.656
RRAS related RAS viral (r-ras) oncogene homolog 0.655
MPZ myelin protein zero 0.654
CXCL8 chemokine (C-X-C motif) ligand 8 0.654
PARD6B par-6 family cell polarity regulator beta 0.653
RNF214 ring finger protein 214 0.653
ACTN4 actinin, alpha 4 0.653
CLASP2 cytoplasmic linker associated protein 2 0.651
RHOJ ras homolog family member J 0.651
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.65
PDE4A phosphodiesterase 4A, cAMP-specific 0.65
FYB1 FYN binding protein 1 0.649
CSRP1 cysteine and glycine-rich protein 1 0.648
KLHDC7A kelch domain containing 7A 0.648
RFPL1 ret finger protein-like 1 0.648
WDR1 WD repeat domain 1 0.648
CD2 CD2 molecule 0.648
CYTH3 cytohesin 3 0.647
TMSB4X thymosin beta 4, X-linked 0.647
TWIST2 twist family bHLH transcription factor 2 0.645
RAP2B RAP2B, member of RAS oncogene family 0.643
SYNJ2 synaptojanin 2 0.642
PECAM1 platelet/endothelial cell adhesion molecule 1 0.641
TRIML1 tripartite motif family-like 1 0.641
SH3KBP1 SH3-domain kinase binding protein 1 0.64
GAS7 growth arrest-specific 7 0.639
TMPRSS12 transmembrane (C-terminal) protease, serine 12 0.638
LIM2 lens intrinsic membrane protein 2, 19kDa 0.638
LONRF3 LON peptidase N-terminal domain and ring finger 3 0.638
ARF4 ADP-ribosylation factor 4 0.637
TJP2 tight junction protein 2 0.637
ISL1 ISL LIM homeobox 1 0.637
THBS4 thrombospondin 4 0.636
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.635
EHBP1 EH domain binding protein 1 0.635
DIAPH1 diaphanous-related formin 1 0.635
AJUBA ajuba LIM protein 0.634
SDC4 syndecan 4 0.633
FGFRL1 fibroblast growth factor receptor-like 1 0.633
UEVLD UEV and lactate/malate dehyrogenase domains 0.631
TNS3 tensin 3 0.629
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.629
RAB4A RAB4A, member RAS oncogene family 0.629
RNF148 ring finger protein 148 0.629
ACTG1 actin gamma 1 0.628
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.628
FBXO38 F-box protein 38 0.627
RTN4 reticulon 4 0.627
GJA1 gap junction protein, alpha 1, 43kDa 0.625
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.623
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.62
RNF44 ring finger protein 44 0.62
GPKOW G patch domain and KOW motifs 0.62
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.618
MAGED1 melanoma antigen family D1 0.618
CTBP1 C-terminal binding protein 1 0.617
TRIM60 tripartite motif containing 60 0.617
RAP1A RAP1A, member of RAS oncogene family 0.616
MYO9B myosin IXB 0.612
PKN1 protein kinase N1 0.611
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.61
CD2AP CD2-associated protein 0.61
GNA12 guanine nucleotide binding protein (G protein) alpha 12 0.61
NHSL2 NHS-like 2 0.608
RNF208 ring finger protein 208 0.605
ICAM3 intercellular adhesion molecule 3 0.605
TRIM42 tripartite motif containing 42 0.603
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.602
PDGFB platelet-derived growth factor beta polypeptide 0.6
AKAP13 A kinase (PRKA) anchor protein 13 0.6
ARHGAP32 Rho GTPase activating protein 32 0.598
TCHP trichoplein, keratin filament binding 0.598
METAP2 methionyl aminopeptidase 2 0.598
POTEF POTE ankyrin domain family, member F 0.596
ARC activity-regulated cytoskeleton-associated protein 0.595
STK26 serine/threonine protein kinase 26 0.595
PTPRD protein tyrosine phosphatase, receptor type, D 0.595
TUBA4A tubulin, alpha 4a 0.593
EPHA4 EPH receptor A4 0.593
FBXL14 F-box and leucine-rich repeat protein 14 0.592
CABLES1 Cdk5 and Abl enzyme substrate 1 0.592
PARD6G par-6 family cell polarity regulator gamma 0.592
LAMP1 lysosomal-associated membrane protein 1 0.591
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.591
KANK1 KN motif and ankyrin repeat domains 1 0.59
DPP7 dipeptidyl-peptidase 7 0.589
TRIM49 tripartite motif containing 49 0.589
NANOS3 nanos homolog 3 (Drosophila) 0.588
RNF141 ring finger protein 141 0.588
CIAO2B cytosolic iron-sulfur assembly component 2B 0.587
GMPR2 guanosine monophosphate reductase 2 0.586
RXFP1 relaxin/insulin-like family peptide receptor 1 0.584
RNF133 ring finger protein 133 0.583
MT1HL1 metallothionein 1H-like 1 0.581
POFUT1 protein O-fucosyltransferase 1 0.58
ITGAV integrin, alpha V 0.579
TRIM48 tripartite motif containing 48 0.579
RAB8A RAB8A, member RAS oncogene family 0.577
AKAP12 A kinase (PRKA) anchor protein 12 0.575
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.574
SHH sonic hedgehog 0.573
OTUD7B OTU deubiquitinase 7B 0.573
TUBB2A tubulin, beta 2A class IIa 0.573
LPAR1 lysophosphatidic acid receptor 1 0.572
ZFAND4 zinc finger, AN1-type domain 4 0.572
ARFIP1 ADP-ribosylation factor interacting protein 1 0.571
F7 coagulation factor VII (serum prothrombin conversion accelerator) 0.57
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.569
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 0.569
TMEM97 transmembrane protein 97 0.569
RAB13 RAB13, member RAS oncogene family 0.566
CD8A CD8a molecule 0.566
ZNF677 zinc finger protein 677 0.565
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.565
TPM2 tropomyosin 2 (beta) 0.563
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.562
LONRF1 LON peptidase N-terminal domain and ring finger 1 0.562
CCL19 chemokine (C-C motif) ligand 19 0.561
APP amyloid beta (A4) precursor protein 0.561
HSPG2 heparan sulfate proteoglycan 2 0.559
ARL16 ADP-ribosylation factor-like 16 0.559
RPS25 ribosomal protein S25 0.559
CCSER2 coiled-coil serine-rich protein 2 0.559
AIF1 allograft inflammatory factor 1 0.556
EPS8L2 EPS8-like 2 0.556
GDNF glial cell derived neurotrophic factor 0.555
CARMIL2 capping protein regulator and myosin 1 linker 2 0.555
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.555
F11R F11 receptor 0.555
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 0.554
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.554
ARHGAP11A Rho GTPase activating protein 11A 0.549
MSX2 msh homeobox 2 0.548
CD34 CD34 molecule 0.546
MYH13 myosin, heavy chain 13, skeletal muscle 0.546
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.546
MFAP3 microfibrillar-associated protein 3 0.544
CCDC177 coiled-coil domain containing 177 0.544
MYLK3 myosin light chain kinase 3 0.544
ERBB3 erb-b2 receptor tyrosine kinase 3 0.544
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.544
PGK1 phosphoglycerate kinase 1 0.543
OPHN1 oligophrenin 1 0.539
COMP cartilage oligomeric matrix protein 0.538
TMEM92 transmembrane protein 92 0.538
RASAL2 RAS protein activator like 2 0.538
SDK1 sidekick cell adhesion molecule 1 0.537
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.537
RTN4RL2 reticulon 4 receptor-like 2 0.536
TPD52L3 tumor protein D52-like 3 0.535
HSPB1 heat shock 27kDa protein 1 0.535
NECTIN1 nectin cell adhesion molecule 1 0.534
EEA1 early endosome antigen 1 0.531
ARF5 ADP-ribosylation factor 5 0.529
TSC2 tuberous sclerosis 2 0.529
AFDN afadin, adherens junction formation factor 0.528
EFHD1 EF-hand domain family, member D1 0.527
TGFA transforming growth factor, alpha 0.526
YAP1 Yes-associated protein 1 0.526
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.526
IFNG interferon, gamma 0.526
FAM220A family with sequence similarity 220, member A 0.523
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.522
TWF1 twinfilin actin binding protein 1 0.521
GDI2 GDP dissociation inhibitor 2 0.521
RAB28 RAB28, member RAS oncogene family 0.52
STARD8 StAR-related lipid transfer (START) domain containing 8 0.518
CLIP2 CAP-GLY domain containing linker protein 2 0.517
MYO5C myosin VC 0.517
FOXI2 forkhead box I2 0.515
DOCK9 dedicator of cytokinesis 9 0.515
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3 0.513
RNF150 ring finger protein 150 0.513
NRG1 neuregulin 1 0.51
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 0.51
BUB1B-PAK6 BUB1B-PAK6 readthrough 0.51
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.509
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 0.509
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B 0.508
DPYSL3 dihydropyrimidinase-like 3 0.507
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.507
CORO1A coronin, actin binding protein, 1A 0.506
NDEL1 nudE neurodevelopment protein 1-like 1 0.506
CCL2 chemokine (C-C motif) ligand 2 0.506
VEGFC vascular endothelial growth factor C 0.505
NKX1-2 NK1 homeobox 2 0.502
S1PR2 sphingosine-1-phosphate receptor 2 0.502
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.502
NOD1 nucleotide-binding oligomerization domain containing 1 0.501
DAAM2 dishevelled associated activator of morphogenesis 2 0.501
UBOX5 U-box domain containing 5 0.501
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog 0.5