Microtubule Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. (Gene Ontology, GO_0005874)
External Link http://amigo.geneontology.org/amigo/term/GO:0005874
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Genes

286 proteins localized to the Microtubule cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
FAM161B family with sequence similarity 161, member B 5.0
KATNAL2 katanin p60 subunit A-like 2 5.0
KIF14 kinesin family member 14 5.0
KLHL22 kelch-like family member 22 5.0
KLHL21 kelch-like family member 21 5.0
SCTR secretin receptor 5.0
CCT2 chaperonin containing TCP1, subunit 2 (beta) 5.0
CEP295 centrosomal protein 295kDa 5.0
NPPC natriuretic peptide C 5.0
KIF11 kinesin family member 11 5.0
KATNAL1 katanin p60 subunit A-like 1 5.0
FAM161A family with sequence similarity 161, member A 5.0
SRPRB signal recognition particle receptor, B subunit 5.0
CFAP20 cilia and flagella associated protein 20 5.0
TCP1 t-complex 1 5.0
TTL tubulin tyrosine ligase 5.0
TUBB4B tubulin, beta 4B class IVb 5.0
TUBB4A tubulin, beta 4A class IVa 5.0
NME7 NME/NM23 family member 7 5.0
ENKD1 enkurin domain containing 1 5.0
SERP1 stress-associated endoplasmic reticulum protein 1 5.0
DLG1 discs, large homolog 1 (Drosophila) 5.0
BOD1 biorientation of chromosomes in cell division 1 5.0
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.0
CLTC clathrin, heavy chain (Hc) 5.0
EFHB EF-hand domain family, member B 5.0
SAXO1 stabilizer of axonemal microtubules 1 5.0
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 5.0
KATNB1 katanin p80 (WD repeat containing) subunit B 1 5.0
CUL3 cullin 3 5.0
TCP11L1 t-complex 11, testis-specific-like 1 5.0
CDK5RAP2 CDK5 regulatory subunit associated protein 2 5.0
MAP9 microtubule-associated protein 9 5.0
REEP2 receptor accessory protein 2 5.0
CIMIP2B ciliary microtubule inner protein 2B 5.0
DNM2 dynamin 2 5.0
DNM1L dynamin 1-like 5.0
NDRG1 N-myc downstream regulated 1 5.0
PARP4 poly (ADP-ribose) polymerase family, member 4 5.0
RADIL Ras association and DIL domains 5.0
SOGA1 suppressor of glucose, autophagy associated 1 5.0
NUMA1 nuclear mitotic apparatus protein 1 5.0
HAUS2 HAUS augmin-like complex, subunit 2 5.0
MID2 midline 2 5.0
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 5.0
TMEM214 transmembrane protein 214 5.0
SHTN1 shootin 1 5.0
MTA1 metastasis associated 1 5.0
CSNK1D casein kinase 1, delta 5.0
SIRT2 sirtuin 2 5.0
CCT8 chaperonin containing TCP1, subunit 8 (theta) 5.0
HAUS1 HAUS augmin-like complex, subunit 1 5.0
SNPH syntaphilin 5.0
HAUS5 HAUS augmin-like complex, subunit 5 5.0
HAUS4 HAUS augmin-like complex, subunit 4 5.0
HAUS7 HAUS augmin-like complex, subunit 7 5.0
HAUS6 HAUS augmin-like complex, subunit 6 5.0
HAUS3 HAUS augmin-like complex, subunit 3 5.0
MNS1 meiosis-specific nuclear structural 1 5.0
BIRC5 baculoviral IAP repeat containing 5 5.0
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 5.0
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 5.0
CCT7 chaperonin containing TCP1, subunit 7 (eta) 5.0
CCT4 chaperonin containing TCP1, subunit 4 (delta) 5.0
MACF1 microtubule-actin crosslinking factor 1 5.0
MTCL1 microtubule crosslinking factor 1 5.0
MAP2K2 mitogen-activated protein kinase kinase 2 5.0
FAM110A family with sequence similarity 110, member A 5.0
CFAP53 cilia and flagella associated protein 53 5.0
SPAG5 sperm associated antigen 5 5.0
SPAG8 sperm associated antigen 8 5.0
ZNF804A zinc finger protein 804A 5.0
TUBG2 tubulin, gamma 2 5.0
CEP57 centrosomal protein 57kDa 5.0
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 5.0
EML3 echinoderm microtubule associated protein like 3 5.0
EML1 echinoderm microtubule associated protein like 1 5.0
EML4 echinoderm microtubule associated protein like 4 5.0
TUBB6 tubulin, beta 6 class V 5.0
TUBB3 tubulin, beta 3 class III 5.0
LRPPRC leucine-rich pentatricopeptide repeat containing 5.0
MPG N-methylpurine-DNA glycosylase 5.0
CENPE centromere protein E, 312kDa 5.0
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 5.0
SELENOS selenoprotein S 5.0
SEPTIN9 septin 9 5.0
SPACA9 sperm acrosome associated 9 5.0
DCXR dicarbonyl/L-xylulose reductase 5.0
RIBC2 RIB43A domain with coiled-coils 2 5.0
CFAP126 cilia and flagella associated protein 126 5.0
CFAP77 cilia and flagella associated protein 77 5.0
TUBA1A tubulin, alpha 1a 5.0
GRAMD2B GRAM domain containing 2B 5.0
NCKAP5L NCK-associated protein 5-like 5.0
CAMSAP1 calmodulin regulated spectrin-associated protein 1 5.0
CEP162 centrosomal protein 162kDa 5.0
TUBGCP3 tubulin, gamma complex associated protein 3 5.0
MAP6 microtubule-associated protein 6 5.0
SPEF1 sperm flagellar 1 5.0
KNTC1 kinetochore associated 1 5.0
DCTN1 dynactin 1 5.0
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 5.0
ARL3 ADP-ribosylation factor-like 3 5.0
TUBA1B tubulin, alpha 1b 5.0
CFAP210 cilia and flagella associated protein 210 5.0
CIMAP1D CIMAP1 family member D 5.0
CIMIP2C ciliary microtubule inner protein 2C 5.0
BEX4 brain expressed, X-linked 4 5.0
CFAP144 cilia and flagella associated protein 144 5.0
DRC4 dynein regulatory complex subunit 4 5.0
CALM1 calmodulin 1 (phosphorylase kinase, delta) 5.0
CALM3 calmodulin 3 (phosphorylase kinase, delta) 5.0
CALM2 calmodulin 2 (phosphorylase kinase, delta) 5.0
MAP10 microtubule-associated protein 10 5.0
CFAP161 cilia and flagella associated protein 161 5.0
MATCAP1 microtubule associated tyrosine carboxypeptidase 1 5.0
MARK4 MAP/microtubule affinity-regulating kinase 4 5.0
CLMP CXADR-like membrane protein 5.0
ZW10 zw10 kinetochore protein 5.0
SKA2 spindle and kinetochore associated complex subunit 2 5.0
SKA3 spindle and kinetochore associated complex subunit 3 5.0
SKA1 spindle and kinetochore associated complex subunit 1 5.0
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 5.0
PACRG PARK2 co-regulated 5.0
MAP3K11 mitogen-activated protein kinase kinase kinase 11 5.0
CDK1 cyclin-dependent kinase 1 5.0
HID1 HID1 domain containing 5.0
HDAC6 histone deacetylase 6 5.0
CFAP52 cilia and flagella associated protein 52 5.0
IQGAP1 IQ motif containing GTPase activating protein 1 5.0
IQGAP2 IQ motif containing GTPase activating protein 2 5.0
KIF9 kinesin family member 9 5.0
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 5.0
CCDC66 coiled-coil domain containing 66 5.0
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 5.0
GTSE1 G-2 and S-phase expressed 1 5.0
BCL10 B-cell CLL/lymphoma 10 5.0
CCSAP centriole, cilia and spindle-associated protein 5.0
CCDC57 coiled-coil domain containing 57 5.0
CFAP45 cilia and flagella associated protein 45 5.0
TUBB2A tubulin, beta 2A class IIa 5.0
TUBB2B tubulin, beta 2B class IIb 5.0
EFHC1 EF-hand domain (C-terminal) containing 1 5.0
EFHC2 EF-hand domain (C-terminal) containing 2 5.0
TUBA4A tubulin, alpha 4a 5.0
ENKUR enkurin, TRPC channel interacting protein 5.0
CAPN6 calpain 6 5.0
TEKT4 tektin 4 5.0
TEKT2 tektin 2 (testicular) 5.0
TEKT3 tektin 3 5.0
TEKT1 tektin 1 5.0
DST dystonin 5.0
RMDN1 regulator of microtubule dynamics 1 5.0
RMDN3 regulator of microtubule dynamics 3 5.0
RMDN2 regulator of microtubule dynamics 2 5.0
TPT1 tumor protein, translationally-controlled 1 5.0
TRIM54 tripartite motif containing 54 5.0
TRIM55 tripartite motif containing 55 5.0
TBCE tubulin folding cofactor E 4.0
ARHGAP18 Rho GTPase activating protein 18 4.0
AKNA AT-hook transcription factor 4.0
TUBGCP2 tubulin, gamma complex associated protein 2 4.0
DPP9 dipeptidyl-peptidase 9 4.0
FSD1 fibronectin type III and SPRY domain containing 1 4.0
RAB3D RAB3D, member RAS oncogene family 4.0
SAA2 serum amyloid A2 4.0
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 4.0
RNF103-CHMP3 RNF103-CHMP3 readthrough 4.0
SPRY2 sprouty homolog 2 (Drosophila) 4.0
CASP1 caspase 1, apoptosis-related cysteine peptidase 4.0
CLIP2 CAP-GLY domain containing linker protein 2 4.0
CHMP1B charged multivesicular body protein 1B 4.0
RNF4 ring finger protein 4 4.0
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 4.0
DYNLT1 dynein, light chain, Tctex-type 1 4.0
CLASP1 cytoplasmic linker associated protein 1 4.0
CHMP1A charged multivesicular body protein 1A 4.0
TBCC tubulin folding cofactor C 4.0
MAP4 microtubule-associated protein 4 4.0
FGF13 fibroblast growth factor 13 4.0
PRC1 protein regulator of cytokinesis 1 4.0
BCAS3 breast carcinoma amplified sequence 3 4.0
CRHBP corticotropin releasing hormone binding protein 4.0
SARM1 sterile alpha and TIR motif containing 1 4.0
SVIL supervillin 4.0
FHDC1 FH2 domain containing 1 4.0
MEFV Mediterranean fever 4.0
ARL6 ADP-ribosylation factor-like 6 4.0
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 4.0
PYCARD PYD and CARD domain containing 4.0
CHMP4C charged multivesicular body protein 4C 4.0
CHMP4B charged multivesicular body protein 4B 4.0
TTLL1 tubulin tyrosine ligase-like family member 1 4.0
ZWILCH zwilch kinetochore protein 4.0
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 4.0
CHMP2A charged multivesicular body protein 2A 4.0
CHMP5 charged multivesicular body protein 5 4.0
MAP1S microtubule-associated protein 1S 4.0
CHMP2B charged multivesicular body protein 2B 4.0
KIF4A kinesin family member 4A 4.0
CHMP7 charged multivesicular body protein 7 4.0
TBCD tubulin folding cofactor D 4.0
CHMP6 charged multivesicular body protein 6 4.0
MAP6D1 MAP6 domain containing 1 3.0
KIF21A kinesin family member 21A 3.0
FBXW11 F-box and WD repeat domain containing 11 3.0
METAP1 methionyl aminopeptidase 1 3.0
TUBA4B tubulin, alpha 4b 3.0
KIF6 kinesin family member 6 3.0
KIF7 kinesin family member 7 3.0
KIF21B kinesin family member 21B 3.0
TUBB tubulin, beta class I 3.0
DNM1 dynamin 1 3.0
TUBA8 tubulin, alpha 8 3.0
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 3.0
KIF5A kinesin family member 5A 3.0
KIFC2 kinesin family member C2 3.0
KIF3A kinesin family member 3A 3.0
DNM3 dynamin 3 3.0
TUBA1C tubulin, alpha 1c 3.0
TOGARAM2 TOG array regulator of axonemal microtubules 2 3.0
MAP1B microtubule-associated protein 1B 3.0
TUBB8B tubulin beta 8B 3.0
IFT70A intraflagellar transport 70A 3.0
KIFC1 kinesin family member C1 3.0
KIF13B kinesin family member 13B 3.0
KIF13A kinesin family member 13A 3.0
KIF5B kinesin family member 5B 3.0
KIF5C kinesin family member 5C 3.0
KIF3C kinesin family member 3C 3.0
KIF3B kinesin family member 3B 3.0
TOGARAM1 TOG array regulator of axonemal microtubules 1 3.0
DCDC2C doublecortin domain containing 2C 3.0
DCDC2B doublecortin domain containing 2B 3.0
KIF16B kinesin family member 16B 3.0
IFT70B intraflagellar transport 70B 3.0
HAUS8 HAUS augmin-like complex, subunit 8 3.0
TUBG1 tubulin, gamma 1 3.0
SAXO2 stabilizer of axonemal microtubules 2 3.0
CLASP2 cytoplasmic linker associated protein 2 3.0
KIF1C kinesin family member 1C 3.0
KIF1B kinesin family member 1B 3.0
KIF1A kinesin family member 1A 3.0
DCDC2 doublecortin domain containing 2 3.0
KIF19 kinesin family member 19 3.0
KIF12 kinesin family member 12 3.0
KIF17 kinesin family member 17 3.0
TUBB8 tubulin, beta 8 class VIII 3.0
KIF2C kinesin family member 2C 3.0
KIF25 kinesin family member 25 3.0
KIF20A kinesin family member 20A 3.0
KIF20B kinesin family member 20B 3.0
MX1 MX dynamin-like GTPase 1 3.0
MX2 MX dynamin-like GTPase 2 3.0
TUBD1 tubulin, delta 1 3.0
KIF22 kinesin family member 22 3.0
KIF23 kinesin family member 23 3.0
KIF27 kinesin family member 27 3.0
KIF24 kinesin family member 24 3.0
MED12 mediator complex subunit 12 3.0
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 3.0
KIF15 kinesin family member 15 3.0
DISC1 disrupted in schizophrenia 1 3.0
TBCB tubulin folding cofactor B 3.0
TUBA3C tubulin, alpha 3c 3.0
TUBA3E tubulin, alpha 3e 3.0
TUBA3D tubulin, alpha 3d 3.0
KIF2B kinesin family member 2B 3.0
CLIP3 CAP-GLY domain containing linker protein 3 3.0
CLIP1 CAP-GLY domain containing linker protein 1 3.0
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.0
AURKC aurora kinase C 3.0
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 3.0
TUBE1 tubulin, epsilon 1 3.0
TUBAL3 tubulin, alpha-like 3 3.0
KIF18B kinesin family member 18B 3.0
SYBU syntabulin (syntaxin-interacting) 3.0
KIF18A kinesin family member 18A 3.0
NCKAP5 NCK-associated protein 5 3.0
REEP4 receptor accessory protein 4 3.0
MAPRE1 microtubule-associated protein, RP/EB family, member 1 3.0
MAPRE3 microtubule-associated protein, RP/EB family, member 3 3.0
MAPRE2 microtubule-associated protein, RP/EB family, member 2 3.0
REEP3 receptor accessory protein 3 3.0
REEP1 receptor accessory protein 1 3.0
AURKB aurora kinase B 3.0